I-TASSER results

I-TASSER results for job id Rv3920c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (187 residues)
MADADTTDFDVDAEAPGGGVREDTATDADEADDQEERLVAEGEIAGDYLEELLDVLDFDG
DIDLDVEGNRAVVSIDGSDDLNKLVGRGGEVLDALQELTRLAVHQKTGVRSRLMLDIARW
RRRRREELAALADEVARRVAETGDREELVPMTPFERKIVHDAVAAVPGVHSESEGVEPER
RVVVLRD

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 \| \| \| \| \| \| \| \| \| MADADTTDFDVDAEAPGGGVREDTATDADEADDQEERLVAEGEIAGDYLEELLDVLDFDGDIDLDVEGNRAVVSIDGSDDLNKLVGRGGEVLDALQELTRLAVHQKTGVRSRLMLDIARWRRRRREELAALADEVARRVAETGDREELVPMTPFERKIVHDAVAAVPGVHSESEGVEPERRVVVLRD
Prediction	CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHCCEEEEEEHCCCCCEEEHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEHCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHCCCCHHHHHHHHHHHHHCCCCEEEEHCCCCCEEEEEHCC
Conf.Score	9877777776655667766555566666666655777766999999999999999899679999997999999996788764676789758999999999999985698579999855689999999999999999999997985995899989999999999979996899977899868999769
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 \| \| \| \| \| \| \| \| \| MADADTTDFDVDAEAPGGGVREDTATDADEADDQEERLVAEGEIAGDYLEELLDVLDFDGDIDLDVEGNRAVVSIDGSDDLNKLVGRGGEVLDALQELTRLAVHQKTGVRSRLMLDIARWRRRRREELAALADEVARRVAETGDREELVPMTPFERKIVHDAVAAVPGVHSESEGVEPERRVVVLRD
Prediction	8655736657366655665455655665665565465355426303500440064160604041436764020303357511200045363140003002200244376312010104403553263035104500530364544240453344102100310472770413043654412000348
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180

                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHCCEEEEEEHCCCCCEEEHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEHCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHCCCCHHHHHHHHHHHHHCCCCEEEEHCCCCCEEEEEHCC
MADADTTDFDVDAEAPGGGVREDTATDADEADDQEERLVAEGEIAGDYLEELLDVLDFDGDIDLDVEGNRAVVSIDGSDDLNKLVGRGGEVLDALQELTRLAVHQKTGVRSRLMLDIARWRRRRREELAALADEVARRVAETGDREELVPMTPFERKIVHDAVAAVPGVHSESEGVEPERRVVVLRD

3gkuA

0.29

0.28

0.97

2.71

MUSTER

LIELQTTSDKLTYEIVEKGSAGFIG--SKPAIIRAKRKETLQDKAIEFLEQVFDANAVDISVEYNE-TEKENVNLKGDDGI--LIGKRGQTLDSLQYLVSLVVNKSSSDYIRVKLDTENYRERRKETLETLAKNIAYKVKRTKRSVSLEPN-PYERRIIHAALQNDKYVVTRSDGEEPFRHVIISLK

3gkuA

0.29

0.28

0.97

3.42

dPPAS

LIELQTTSDKLTYEIVEKGSAGFIGSKP--AIIRAKRKETLQDKAIEFLEQVFDANAVDISVEYNETEK-ENVNLKGDDGI--LIGKRGQTLDSLQYLVSLVVNKSSSDYIRVKLDTENYRERRKETLETLAKNIAYKVKRTKRSVSLEPN-PYERRIIHAALQNDKYVVTRSDGEEPFRHVIISLK

3gkuA

0.29

0.28

0.97

4.43

wdPPAS

LIELQTTSDKLTYEIVEKGSAGFIG--SKPAIIRAKRKETLQDKAIEFLEQVFDANAVDISVEYNE-TEKENVNLKG--DDGILIGKRGQTLDSLQYLVSLVVNKSSSDYIRVKLDTENYRERRKETLETLAKNIAYKVKRTKRSVSLEPN-PYERRIIHAALQNDKYVVTRSDGEEPFRHVIISLK

3gkuA

0.29

0.28

0.97

3.30

wMUSTER

LIELQTTSDKLTYEIVEKGSAGFIG--SKPAIIRAKRKETLQDKAIEFLEQVFDANAVDISVEYNE-TEKENVNLKGDDG--ILIGKRGQTLDSLQYLVSLVVNKSSSDYIRVKLDTENYRERRKETLETLAKNIAYKVKRTKRSVSLEPN-PYERRIIHAALQNDKYVVTRSDGEEPFRHVIISLK

3gkuA

0.29

0.28

0.97

4.51

wPPAS

LIELQTTSDKLTYEIVEKGSAGFIG--SKPAIIRAKRKETLQDKAIEFLEQVFDANAVDISVEYNE-TEKENVNLKGDD--GILIGKRGQTLDSLQYLVSLVVNKSSSDYIRVKLDTENYRERRKETLETLAKNIAYKVKRTKRSVSLEPN-PYERRIIHAALQNDKYVVTRSDGEEPFRHVIISLK

3gkuA

0.29

0.28

0.97

11.11

dPPAS2

LIELQTTSDKLTYEIVEKGSAGFIGSKP--AIIRAKRKETLQDKAIEFLEQVFDANAVDISVEYNETEK-ENVNLKGDDGI--LIGKRGQTLDSLQYLVSLVVNKSSSDYIRVKLDTENYRERRKETLETLAKNIAYKVKRTKRSVSLEPN-PYERRIIHAALQNDKYVVTRSDGEEPFRHVIISLK

3gkuA

0.29

0.28

0.97

3.69

PPAS

LIELQTTSDKLTYEIVEKGSAGFIG--SKPAIIRAKRKETLQDKAIEFLEQVFDANAVDISVEYNE-TEKENVNLKGDDGI--LIGKRGQTLDSLQYLVSLVVNKSSSDYIRVKLDTENYRERRKETLETLAKNIAYKVKRTKRSVSLEPN-PYERRIIHAALQNDKYVVTRSDGEEPFRHVIISLK

3gkuA

0.29

0.28

0.97

4.59

Env-PPAS

LIELQTTSDKLTYEIVEKGSAGFIG--SKPAIIRAKRKETLQDKAIEFLEQVFDANAVDISVEYNE-TEKENVNLKGDDGI--LIGKRGQTLDSLQYLVSLVVNKSSSDYIRVKLDTENYRERRKETLETLAKNIAYKVKRTKRSVSLEPN-PYERRIIHAALQNDKYVVTRSDGEEPFRHVIISLK

2pt7G

0.15

0.12

0.76

1.28

MUSTER

----------------------------------------KLHEIKQELKDLFSHLPYKNKVEVSLYEPGVLLIDIDGEDSALLIGEKGYRYKALSYLLFNWIHPTYG--YSIRLEISTFLQNQEKVMDTQLQSVIMTVHEVGK-GQMKAPDGVLTYIALKKLRKANKYVSIKTNLNDEKYIVIN--

2pt7G

0.15

0.12

0.76

1.52

dPPAS

----------------------------------------KLHEIKQELKDLFSHLPYKNKVEVSLYEPGVLLIDIDGEDSALLIGEKGYRYKALSYLLFNWIHPTYG--YSIRLEISTFLQNQEKVMDTQLQSVIMTVHEVGK-GQMKAPDGVLTYIALKKLRKANKYVSIKTNLNDEKYIVIN--

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 4 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=1.24

Estimated TM-score = 0.89±0.07

Estimated RMSD = 2.8±2.0Å

Download Model 2

C-score=-2.50

Download Model 3

C-score=-2.86

Download Model 4

C-score=-4.45

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	3gkuA	0.922	1.25	0.293	0.968
2	3swhA	0.494	4.95	0.068	0.759
3	4ap2B	0.487	4.61	0.065	0.743
4	5b86A	0.487	5.34	0.093	0.818
5	4rl5A	0.471	4.93	0.064	0.781
6	1t3tA	0.471	5.73	0.092	0.861
7	3p8cB	0.468	5.20	0.045	0.786
8	2wzkA	0.466	4.76	0.085	0.727
9	2pftA	0.466	5.33	0.039	0.807
10	2hyeC1	0.465	4.86	0.038	0.733

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.10	5	2xquA	CVM	Rep, Mult	124,128
2	0.04	2	1b7yB	MG	Rep, Mult	57,58,80,83,84
3	0.04	2	3e5uC	3C4	Rep, Mult	128,131,132
4	0.04	2	2iefB	NUC	Rep, Mult	175,180
5	0.04	2	1smyF	MG	Rep, Mult	123,177,180
6	0.04	2	1l9nB	CA	Rep, Mult	159,160,172
7	0.04	2	5ccgC	CA	Rep, Mult	133,136
8	0.02	1	3d1lA	MPR	Rep, Mult	131,150
9	0.02	1	1k9zA	ZN	Rep, Mult	51,127
10	0.02	1	3qnfA	UUU	Rep, Mult	147,172,173,183
11	0.02	1	3i8gF	MG	Rep, Mult	87,88
12	0.02	1	2xquC	CVM	Rep, Mult	136,139
13	0.02	1	3ow7A	CU1	Rep, Mult	96,151
14	0.02	1	2a68P	MG	Rep, Mult	127,130
15	0.02	1	1ggyB	YB	Rep, Mult	86,90,123,127
16	0.02	1	3perB	PO4	Rep, Mult	50,63,95,98,114

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	1g8mA	0.408	5.33	0.068	0.690	3.5.4.10,2.1.2.3	NA
2	0.060	1gk8A	0.429	4.91	0.070	0.674	4.1.1.39	NA
3	0.060	1bxnA	0.415	4.88	0.075	0.652	4.1.1.39	NA
4	0.060	2d69A	0.418	4.78	0.050	0.647	4.1.1.39	NA
5	0.060	1t3tA	0.471	5.73	0.092	0.861	6.3.5.3	NA
6	0.060	1l9mB	0.439	5.67	0.051	0.770	2.3.2.13	NA
7	0.060	3ciaA	0.429	5.63	0.017	0.770	3.4.11.-	127
8	0.060	2agsA	0.408	5.80	0.041	0.759	3.2.1.18	83
9	0.060	2vdcF	0.426	4.58	0.043	0.642	1.4.1.13	46
10	0.060	1s0kA	0.364	5.56	0.071	0.642	3.2.1.18	NA
11	0.060	2g25A	0.413	5.70	0.054	0.738	1.2.4.1	NA
12	0.060	9rubA	0.412	4.95	0.038	0.658	4.1.1.39	NA
13	0.060	3ebgA	0.415	5.34	0.041	0.706	3.4.11.-	NA
14	0.060	2gtqA	0.410	6.02	0.049	0.781	3.4.11.2	NA
15	0.060	1gehA	0.407	5.08	0.076	0.652	4.1.1.39	NA
16	0.060	1bxnE	0.415	4.88	0.075	0.652	4.1.1.39	77
17	0.060	2dqmA	0.415	5.70	0.051	0.759	3.4.11.2	NA
18	0.060	3h09B	0.409	5.39	0.038	0.695	3.4.21.72	87
19	0.060	1gehC	0.407	5.08	0.076	0.652	4.1.1.39	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.58	0.946	1.10	0.29	0.98	3gkuA	GO:0003676
1	0.07	0.494	4.90	0.08	0.76	3swhB	GO:0000149 GO:0005737 GO:0005886 GO:0006887 GO:0007268 GO:0007269 GO:0016020 GO:0016082 GO:0017075 GO:0019904 GO:0019992 GO:0030054 GO:0030154 GO:0030507 GO:0035556 GO:0042734 GO:0042803 GO:0043005 GO:0043195 GO:0043234 GO:0045202 GO:0046872 GO:0046982 GO:0047485 GO:0060076 GO:0060291
2	0.07	0.487	4.61	0.07	0.74	4ap2B	GO:0000082 GO:0000122 GO:0000139 GO:0000165 GO:0000209 GO:0000278 GO:0000902 GO:0001701 GO:0001831 GO:0004842 GO:0005634 GO:0005654 GO:0005737 GO:0005794 GO:0005827 GO:0005829 GO:0006357 GO:0006511 GO:0006513 GO:0006810 GO:0006888 GO:0007050 GO:0007080 GO:0007229 GO:0007369 GO:0008054 GO:0008284 GO:0016020 GO:0016055 GO:0016192 GO:0016477 GO:0016567 GO:0017145 GO:0030030 GO:0030332 GO:0031208 GO:0031461 GO:0031463 GO:0031625 GO:0032467 GO:0035024 GO:0040016 GO:0042787 GO:0042803 GO:0043149 GO:0043161 GO:0044346 GO:0045842 GO:0046982 GO:0048208 GO:0061630 GO:0070062 GO:0072576 GO:0090090 GO:0097193
3	0.07	0.406	5.38	0.05	0.69	4rl5A	GO:0000145 GO:0005576 GO:0005618 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0006810 GO:0006887 GO:0009524 GO:0016020
4	0.07	0.466	5.33	0.04	0.81	2pftA	GO:0000145 GO:0005737 GO:0005815 GO:0005829 GO:0005886 GO:0006810 GO:0006887 GO:0015031 GO:0016020 GO:0032584 GO:0034451 GO:0061024 GO:2000535
5	0.07	0.497	4.84	0.06	0.80	4rl5B	GO:0000145 GO:0005576 GO:0005618 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0006810 GO:0006887 GO:0009524 GO:0016020
6	0.07	0.429	5.62	0.05	0.76	2hs3A	GO:0000166 GO:0000287 GO:0004642 GO:0005524 GO:0005737 GO:0006164 GO:0006189 GO:0006541 GO:0009156 GO:0016874 GO:0046872
7	0.07	0.469	4.78	0.09	0.73	4jghD	GO:0000082 GO:0004842 GO:0004872 GO:0005262 GO:0005829 GO:0006511 GO:0007050 GO:0008283 GO:0008285 GO:0016032 GO:0016567 GO:0031461 GO:0031466 GO:0031625 GO:0038128 GO:0042787 GO:0061630 GO:0070588 GO:0097193
8	0.07	0.453	4.73	0.04	0.70	4a0kA	GO:0000082 GO:0000715 GO:0000717 GO:0001701 GO:0005654 GO:0006281 GO:0006283 GO:0006293 GO:0006294 GO:0006295 GO:0006296 GO:0006511 GO:0006974 GO:0007050 GO:0008284 GO:0008285 GO:0016032 GO:0016567 GO:0030097 GO:0030853 GO:0031461 GO:0031464 GO:0031625 GO:0033683 GO:0035019 GO:0042769 GO:0042787 GO:0043161 GO:0051246 GO:0061630 GO:0070911 GO:0080008 GO:0097193 GO:1900087 GO:2000001 GO:2000819
9	0.07	0.445	4.75	0.02	0.68	4a0lE	GO:0000715 GO:0000717 GO:0003684 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0006281 GO:0006283 GO:0006293 GO:0006294 GO:0006295 GO:0006296 GO:0006511 GO:0006974 GO:0007049 GO:0016567 GO:0031175 GO:0031461 GO:0031465 GO:0031625 GO:0033683 GO:0035518 GO:0042769 GO:0042787 GO:0045732 GO:0061630 GO:0070062 GO:0070911 GO:0070914 GO:1900087
10	0.07	0.466	4.76	0.09	0.73	2wzkA	GO:0006511 GO:0016567 GO:0021799 GO:0021942 GO:0031461 GO:0031466 GO:0031625 GO:0042787 GO:0046982 GO:0061630
11	0.06	0.456	5.23	0.07	0.74	1ldjA	GO:0000082 GO:0000086 GO:0000209 GO:0002223 GO:0004842 GO:0005654 GO:0005829 GO:0006511 GO:0006513 GO:0006915 GO:0007050 GO:0008283 GO:0008285 GO:0009887 GO:0016032 GO:0016055 GO:0016567 GO:0019005 GO:0031146 GO:0031461 GO:0031625 GO:0038061 GO:0038095 GO:0042787 GO:0043161 GO:0050852 GO:0051403 GO:0051437 GO:0061630 GO:0097193 GO:1990452
12	0.06	0.411	5.47	0.03	0.72	4y21A	GO:0000149 GO:0005737 GO:0005886 GO:0006887 GO:0007268 GO:0007269 GO:0016020 GO:0016082 GO:0017075 GO:0019904 GO:0019992 GO:0030054 GO:0030154 GO:0030507 GO:0035556 GO:0042734 GO:0042803 GO:0043005 GO:0043195 GO:0043234 GO:0045202 GO:0046872 GO:0046982 GO:0047485 GO:0060076 GO:0060291
13	0.06	0.378	5.82	0.04	0.69	5a5tC	GO:0001731 GO:0003723 GO:0003743 GO:0005737 GO:0005852 GO:0006412 GO:0006413 GO:0006446 GO:0016282 GO:0031369 GO:0033290 GO:0071541
14	0.06	0.506	5.31	0.09	0.86	2b7mB	GO:0000131 GO:0000145 GO:0001927 GO:0005546 GO:0005886 GO:0005933 GO:0005934 GO:0005935 GO:0006810 GO:0006887 GO:0006893 GO:0007266 GO:0015031 GO:0017049 GO:0030133 GO:0031410 GO:0051601 GO:0090522
15	0.06	0.446	5.50	0.03	0.76	2pfvA	GO:0000131 GO:0000145 GO:0001927 GO:0005546 GO:0005886 GO:0005933 GO:0005934 GO:0005935 GO:0006810 GO:0006887 GO:0006893 GO:0007266 GO:0015031 GO:0017049 GO:0030133 GO:0031410 GO:0051601 GO:0090522
16	0.06	0.390	5.88	0.11	0.71	1r9jB	GO:0003824 GO:0004802 GO:0008152 GO:0016740 GO:0046872
17	0.06	0.342	5.56	0.07	0.60	1f00I	GO:0007155 GO:0009279 GO:0009405 GO:0016020 GO:0016021
18	0.06	0.471	5.82	0.09	0.87	4lgyA	GO:0000166 GO:0004642 GO:0005524 GO:0005737 GO:0006164 GO:0006189 GO:0006541 GO:0009156 GO:0016874 GO:0046872

Consensus prediction of GO terms

Molecular Function	GO:0003676
GO-Score	0.58
Biological Processes	GO:0032940	GO:0016192
GO-Score	0.37	0.37
Cellular Component	GO:0071944	GO:0044444
GO-Score	0.37	0.37

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.