I-TASSER results

I-TASSER results for job id Rv3910

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (1184 residues)
MRPSPGEVPTASQRQPELSDAALVSHSWAMAFATLISRITGFARIVLLAAILGAALASSF
SVANQLPNLVAALVLEATFTAIFVPVLARAEQDDPDGGAAFVRRLVTLATTLLLGATTLS
VLAAPLLVRLMLGTNPQVNEPLTTAFAYLLLPQVLVYGLSSVFMAILNTRNVFGPPAWAP
VVNNVVAIATLAVYLAVPGELSVDPVRMGNAKLLVLGIGTTAGVFAQTAVLLVAIRREHI
SLRPLWGIDQRLKRFGAMAAAMVLYVLISQLGLVVGNRIASTAAASGPAIYNYTWLVLML
PFGMIGVTVLTVVMPRLSRNAAADDTPAVLADLSLATRLTMITLIPTVAFMTVGGPAIGS
ALFAYGNFGDVDAGYLGAAIALSAFTLIPYALVLLQLRVFYAREQPWTPITIIVVITGVK
ILGSLLAPHITGDPQLVAAYLGLANGLGFLAGTIVGYYILRRALRPDGGQLIGVGEARTV
LVTVAASLLAGLLAHVADRLLGLSELTAHAGSVGSLLRLSVLALIMLPILAAVTLCARVP
EARAALDAVRARIRSRRLKTGPQTQNVLDQSSRPGPVTYPERRRLAPPRGKSVVHEPIRR
RPPEQVARAGRAKGPEVIDRPSENASFGAASGAELPRPVADELQLDAPAGRDPGPVSRPH
PSDLQNGDLPADAARGPIAFDALREPDRESSAPPDDVQLVPGARIANGRYRLLIFHGGVP
PLQFWQALDTALDRQVALTFVDPQGVLPDDVLQETLSRTLRLSRIDKPGVARVLDVVHTR
AGGLVVAEWIRGGSLQEVADTSPSPVGAIRAMQSLAAAADAAHRAGVALSIDHPSRVRVS
IDGDVVLAYPATMPDANPQDDIRGIGASLYALLVNRWPLPEAGVRSGLAPAERDTAGQPI
EPADIDRDIPFQISAVAARSVQGDGGIRSASTLLNLMQQATAVADRTEVLGPIDEAPVSA
APRTSAPNSETYTRRRRNLLIGIGAGAAVLMVALLVLASVLSRIFGDVSGGLNKDELGLN
APTASTSAASSAPPGSVVKPTKVTVFSPDGGADNPGEADLAIDGNPATSWKTDIYTDPVP
FPSFKNGVGLMLQLPQATVVGTVAIDVASTGTKVEIRSASTPTPATLEDTAVLTSATALR
PGHNTISVEAAAPTSNLLVWISTLGTTDGKSQADISEITIYAAS

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 500 520 540 560 580 600 620 640 660 680 700 720 740 760 780 800 820 840 860 880 900 920 940 960 980 1000 1020 1040 1060 1080 1100 1120 1140 1160 1180 \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| MRPSPGEVPTASQRQPELSDAALVSHSWAMAFATLISRITGFARIVLLAAILGAALASSFSVANQLPNLVAALVLEATFTAIFVPVLARAEQDDPDGGAAFVRRLVTLATTLLLGATTLSVLAAPLLVRLMLGTNPQVNEPLTTAFAYLLLPQVLVYGLSSVFMAILNTRNVFGPPAWAPVVNNVVAIATLAVYLAVPGELSVDPVRMGNAKLLVLGIGTTAGVFAQTAVLLVAIRREHISLRPLWGIDQRLKRFGAMAAAMVLYVLISQLGLVVGNRIASTAAASGPAIYNYTWLVLMLPFGMIGVTVLTVVMPRLSRNAAADDTPAVLADLSLATRLTMITLIPTVAFMTVGGPAIGSALFAYGNFGDVDAGYLGAAIALSAFTLIPYALVLLQLRVFYAREQPWTPITIIVVITGVKILGSLLAPHITGDPQLVAAYLGLANGLGFLAGTIVGYYILRRALRPDGGQLIGVGEARTVLVTVAASLLAGLLAHVADRLLGLSELTAHAGSVGSLLRLSVLALIMLPILAAVTLCARVPEARAALDAVRARIRSRRLKTGPQTQNVLDQSSRPGPVTYPERRRLAPPRGKSVVHEPIRRRPPEQVARAGRAKGPEVIDRPSENASFGAASGAELPRPVADELQLDAPAGRDPGPVSRPHPSDLQNGDLPADAARGPIAFDALREPDRESSAPPDDVQLVPGARIANGRYRLLIFHGGVPPLQFWQALDTALDRQVALTFVDPQGVLPDDVLQETLSRTLRLSRIDKPGVARVLDVVHTRAGGLVVAEWIRGGSLQEVADTSPSPVGAIRAMQSLAAAADAAHRAGVALSIDHPSRVRVSIDGDVVLAYPATMPDANPQDDIRGIGASLYALLVNRWPLPEAGVRSGLAPAERDTAGQPIEPADIDRDIPFQISAVAARSVQGDGGIRSASTLLNLMQQATAVADRTEVLGPIDEAPVSAAPRTSAPNSETYTRRRRNLLIGIGAGAAVLMVALLVLASVLSRIFGDVSGGLNKDELGLNAPTASTSAASSAPPGSVVKPTKVTVFSPDGGADNPGEADLAIDGNPATSWKTDIYTDPVPFPSFKNGVGLMLQLPQATVVGTVAIDVASTGTKVEIRSASTPTPATLEDTAVLTSATALRPGHNTISVEAAAPTSNLLVWISTLGTTDGKSQADISEITIYAAS
Prediction	CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHCCCCCCEEEEEEEEEHCCCEEEEEEHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEHCCEEEEEEEHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEHCCCCCCCEEHCCCCEEEEEHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHCCCCEEEEEEEEEHCCCCCEEEEEHCCCCCCCCCCCCCEHCCCCHCCCCEEEEEHCCCCCCCEEEEEHCCCCCCCCCCEEEEEEEEEEHCC
Conf.Score	99889999888777766566569999999999999999999999999999996799999999999999999999999999999999999998686899999999999999999999999999999999986389986799999999999999999999999999999986875677899999999999999999986577677876667755778899999999999999999999989866666788889999999999999999999999999999997578768999999999999999999999999999999999987879999999999999999999999999999999999999985899999999999999999999999999999999998865646899999999999999999999875787589999999999999999999999999986777876546889999999999999999999999999755555665559999999999999999999999999998999999999999985678888888777666788887777776677888777776666767788777777777778877888888888888888888888888887778888888888888887777788888887778888888889888888888888777765568758986553788876898767765587589999858888888999999999999985579866778888886897999987679987999998699999999999999999999999895445688774898589869997455578888566799999999999985888899998877654546788888986776788877899999999767889887689998887755677888777888888888888888888888777777665445789999999999999998865567888888888888899888888888888887777665565888999885555765689999987776667888998888886999996898578999999789997899997788999988766655456555787689995789887589999858999999874799999999769
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 500 520 540 560 580 600 620 640 660 680 700 720 740 760 780 800 820 840 860 880 900 920 940 960 980 1000 1020 1040 1060 1080 1100 1120 1140 1160 1180 \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| MRPSPGEVPTASQRQPELSDAALVSHSWAMAFATLISRITGFARIVLLAAILGAALASSFSVANQLPNLVAALVLEATFTAIFVPVLARAEQDDPDGGAAFVRRLVTLATTLLLGATTLSVLAAPLLVRLMLGTNPQVNEPLTTAFAYLLLPQVLVYGLSSVFMAILNTRNVFGPPAWAPVVNNVVAIATLAVYLAVPGELSVDPVRMGNAKLLVLGIGTTAGVFAQTAVLLVAIRREHISLRPLWGIDQRLKRFGAMAAAMVLYVLISQLGLVVGNRIASTAAASGPAIYNYTWLVLMLPFGMIGVTVLTVVMPRLSRNAAADDTPAVLADLSLATRLTMITLIPTVAFMTVGGPAIGSALFAYGNFGDVDAGYLGAAIALSAFTLIPYALVLLQLRVFYAREQPWTPITIIVVITGVKILGSLLAPHITGDPQLVAAYLGLANGLGFLAGTIVGYYILRRALRPDGGQLIGVGEARTVLVTVAASLLAGLLAHVADRLLGLSELTAHAGSVGSLLRLSVLALIMLPILAAVTLCARVPEARAALDAVRARIRSRRLKTGPQTQNVLDQSSRPGPVTYPERRRLAPPRGKSVVHEPIRRRPPEQVARAGRAKGPEVIDRPSENASFGAASGAELPRPVADELQLDAPAGRDPGPVSRPHPSDLQNGDLPADAARGPIAFDALREPDRESSAPPDDVQLVPGARIANGRYRLLIFHGGVPPLQFWQALDTALDRQVALTFVDPQGVLPDDVLQETLSRTLRLSRIDKPGVARVLDVVHTRAGGLVVAEWIRGGSLQEVADTSPSPVGAIRAMQSLAAAADAAHRAGVALSIDHPSRVRVSIDGDVVLAYPATMPDANPQDDIRGIGASLYALLVNRWPLPEAGVRSGLAPAERDTAGQPIEPADIDRDIPFQISAVAARSVQGDGGIRSASTLLNLMQQATAVADRTEVLGPIDEAPVSAAPRTSAPNSETYTRRRRNLLIGIGAGAAVLMVALLVLASVLSRIFGDVSGGLNKDELGLNAPTASTSAASSAPPGSVVKPTKVTVFSPDGGADNPGEADLAIDGNPATSWKTDIYTDPVPFPSFKNGVGLMLQLPQATVVGTVAIDVASTGTKVEIRSASTPTPATLEDTAVLTSATALRPGHNTISVEAAAPTSNLLVWISTLGTTDGKSQADISEITIYAAS
Prediction	64464464455555566443320000011101212211211121011100010000000011011101101211101110000000002025634630230011001120121022112011201211000001145311300010011021112111210110000001100000021012202011101111001112222212312210000001011100100211010001213220101030142001000011111101211010011000001100000000000010000101011010000000010031015632630240012000000010122011010102100000011010134002000100111010111102100000000011000000100010001010001100000112100000000000000100000011000010132202101210010000000001000000110000000010012000001000100001101110110020010310230031011102222243334444444444444424344444244443342124223324244244344142442244444444444444444444444434343244444444434424544444443433443443423442444444444434234234224230102220141010000102033060300000020622424400430240033103041100000000023440000000004144033006431303200300220030021013110000101111010144020000000102534121000000000000000010123442200020014226441140440244013202400230045534414242023104212212311211322432123222322424234342222211111000000001011110000000111243434454444442444444444443442142451431415254444541432244534141214313442424412300001030544340230203043430301010042454443544443244342445424141565450300000002005464413030130414358
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380                 400                 420                 440                 460                 480                 500                 520                 540                 560                 580                 600                 620                 640                 660                 680                 700                 720                 740                 760                 780                 800                 820                 840                 860                 880                 900                 920                 940                 960                 980                1000                1020                1040                1060                1080                1100                1120                1140                1160                1180

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Sec.Str
Seq

CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHCCCCCCEEEEEEEEEHCCCEEEEEEHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEHCCEEEEEEEHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEHCCCCCCCEEHCCCCEEEEEHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHCCCCEEEEEEEEEHCCCCCEEEEEHCCCCCCCCCCCCCEHCCCCHCCCCEEEEEHCCCCCCCEEEEEHCCCCCCCCCCEEEEEEEEEEHCC
MRPSPGEVPTASQRQPELSDAALVSHSWAMAFATLISRITGFARIVLLAAILGAALASSFSVANQLPNLVAALVLEATFTAIFVPVLARAEQDDPDGGAAFVRRLVTLATTLLLGATTLSVLAAPLLVRLMLGTNPQVNEPLTTAFAYLLLPQVLVYGLSSVFMAILNTRNVFGPPAWAPVVNNVVAIATLAVYLAVPGELSVDPVRMGNAKLLVLGIGTTAGVFAQTAVLLVAIRREHISLRPLWGIDQRLKRFGAMAAAMVLYVLISQLGLVVGNRIASTAAASGPAIYNYTWLVLMLPFGMIGVTVLTVVMPRLSRNAAADDTPAVLADLSLATRLTMITLIPTVAFMTVGGPAIGSALFAYGNFGDVDAGYLGAAIALSAFTLIPYALVLLQLRVFYAREQPWTPITIIVVITGVKILGSLLAPHITGDPQLVAAYLGLANGLGFLAGTIVGYYILRRALRPDGGQLIGVGEARTVLVTVAASLLAGLLAHVADRLLGLSELTAHAGSVGSLLRLSVLALIMLPILAAVTLCARVPEARAALDAVRARIRSRRLKTGPQTQNVLDQSSRPGPVTYPERRRLAPPRGKSVVHEPIRRRPPEQVARAGRAKGPEVIDRPSENASFGAASGAELPRPVADELQLDAPAGRDPGPVSRPHPSDLQNGDLPADAARGPIAFDALREPDRESSAPPDDVQLVPGARIANGRYRLLIFHGGVPPLQFWQALDTALDRQVALTFVDPQGVLPDDVLQETLSRTLRLSRIDKPGVARVLDVVHTRAGGLVVAEWIRGGSLQEVADTSPSPVGAIRAMQSLAAAADAAHRAGVALSIDHPSRVRVSIDGDVVLAYPATMPDANPQDDIRGIGASLYALLVNRWPLPEAGVRSGLAPAERDTAGQPIEPADIDRDIPFQISAVAARSVQGDGGIRSASTLLNLMQQATAVADRTEVLGPIDEAPVSAAPRTSAPNSETYTRRRRNLLIGIGAGAAVLMVALLVLASVLSRIFGDVSGGLNKDELGLNAPTASTSAASSAPPGSVVKPTKVTVFSPDGGADNPGEADLAIDGNPATSWKTDIYTDPVPFPSFKNGVGLMLQLPQATVVGTVAIDVASTGTKVEIRSASTPTPATLEDTAVLTSATALRPGHNTISVEAAAPTSNLLVWISTLGTTDGKSQADISEITIYAAS

5ijoJ

0.10

0.09

0.94

1.48

MUSTER

HWRRLLEGLSYYKPPSPSSAEKVKANSPLKELGLRISKFLEEQSVQLLQCYLQEDYRGTRQSQALILKIADYYYEERTCILRCVLHLLTYFQDERHPYRVEYADKLEKELVSKYRQQFEELYKTEAPTWETHGNLMTERQVSRWFVQCLREQSMLLEIIFLYYAYF-------------EMAPSDLLVLTKMFKEQGFGSRQTNRLVDETMDPFVDRIGYFSALILVEGMDIESLHKCALDDRRELHQFAQDGLICQDMDCLMLTFGDIPHHAPVLLAWALLR--HTLNPEETSSVVRKIGGTAIQLNVFQYLTRLLQSLASGGNDCTTSTACMCVYGLLSFVLTSLTLGNQQDIIDTACEVLADPLFWGTEPTSGLGIILDSVCGMFPLSPLLQLLRALVSGKSTAKKVYSFLDKMFYNELYRRQTPKLLYPLGGQTNLRIPQGTVGQVMSWTLFTCEIEMLLHVVSTADVIQH-------CQRVKPIIDLVHKVISTDLSIADCLLPITSRIYMLLQRLTTVISPPVDVIASCVNCLTVLAARPAKVWTDLRHTGFLPFVAHMNAGGYGNLLMNSEQPQGEYGVTIAFLRLITTLVKGQLGSTQSQGLVPCVMFVLKEMLPSYHKWRYNSHGVGCLILELIHAILNLCHETDLHSSHTPSLQFLCICSLAYTEAGQTVINIMGIGVDTIDMVMAAGQGQGQLLI-------------------KTVKLAFSVTNNVIRLKPPSNVVSPLEQALSQHG------AGNNLIAVLAKYIYPALPRLAI-----QLLKRLATVAPM-NDAAAIRDAFLTRLQSKIE-------DMRIKVMITQPGLIELFLNLVNCLRLGSMKCTLLLILLRQW--KRELGSVQQLMSAFITVLQMKEMKVSDIPQYSQLVLNVCETLQEEVIALFHRDQRDGVCVLGLHLAKELCEVDEDGDSLQVTRRLPILPTLLTTLEVSLRMKQNLHFTEATLHLLLTLARTQQGATAVAGAGPLLSVYQLSTNGTAQTPSASRKSLDAPSWPGVYRLSMSLMEQLLKTLRYNFLPEALD-QERTLQCLNAVRTVQSLACLDHTVGFILQLSNFMKEWHLMRDIQVNLGYLCQACTSLLHSRKMLQHYLQNKNGDGLPSAVAQRVQRTEASEQ-----QALHTV----QYGLLKILSKTLA

3otvA

1.00

0.21

1.25

dPPAS

------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQLVPGARIANGRYRLLIFHGGVPPLQFWQALDTALDRQVALTFVDPQGVLPDDVLQETLSRTLRLSRIDKPGVARVLDVVHTRAGGLVVAEWIRGGSLQEVADTSPSPVGAIRAMQSLAAAADAAHRAGVALSIDHPSRVRVSIDGDVVLAYPATMPDANPQDDIRGIGASLYALLVNRWPLPEAGVRSGLAPAERDTAGQPIEPADIDRDIPFQISAVAARSVQGDGGIRSASTLLNLMQQATAVADRTEVL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

3otvA

1.00

0.21

2.27

wdPPAS

------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQLVPGARIANGRYRLLIFHGGVPPLQFWQALDTALDRQVALTFVDPQGVLPDDVLQETLSRTLRLSRIDKPGVARVLDVVHTRAGGLVVAEWIRGGSLQEVADTSPSPVGAIRAMQSLAAAADAAHRAGVALSIDHPSRVRVSIDGDVVLAYPATMPDANPQDDIRGIGASLYALLVNRWPLPEAGVRSGLAPAERDTAGQPIEPADIDRDIPFQISAVAARSVQGDGGIRSASTLLNLMQQATAVADRTEVL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

1u6gC

0.11

0.10

0.86

1.45

wMUSTER

MT---SSDKTELQKDSIKLDDDSERKVVKMILKLLED----GEVQNLAVKCLGPLVS-EYQVETIVDTLCTNMLS--QLRDISSIGLKTVIGEPSALAANVCKKITGRLTSAIVSVQLEALDIMADMLSRQGGLLVNFHPSILTCLLPQLTLAVRKRTIIALGHLVMSCFVDLIEHLLSELSKNDTYIQCIAAISRQAGHRIGEYLEVDDDELREYCIQAFESFVRRVYPHVSTIINICLKY-LTYDMSWKVRRAAAKCLDAVVSMLPEFYKTVSPALISRFKERKADVFHAYLSLLKQTPLTMLQSQV-PNIVKALHKQMKEKSVKTRQCCFNMLTELVNVL--PGALHIPVLVPGIIFSLNDKSS--IDALSCLYVILCNHSPQVFHPHVQALVPPVVACVGDPFYKITSEALLVTQQLVKVIRATPYI--KDLFTCTIKRLIDQEVKERAISCMGQIICNLGDN-LGSDLPNTLQIFLERLKNEITRLTTVKALTLIAGSPLKIDLRPVLGEGVPILASFL--RALKLGTLSALDIKNYAAMIDAVLDELPPLISESDMHVSQMAISFLTTLAKVYPSSLSKISGSILNELIGLVRSPLLQGGALSAMLDFFQALVVTGTNNLGYMDLLRMLTGPVYSQTHKQSYYSIAKCVAALTRACPKEGPAVVGQFIQD-----------------VKNSRSTDSIRLLALL--SLGEVG--------HHIDLSGQLELKSVILEAFSSPSEEVKSAASYALGSISVGNLPEYLPFV--------------------LQEITSQPKRQYLLLHSLKEIISSASVVGLKPYV------ENI------ALLLK---HCECAE--EGTRNVVAECLGKLTLI------DPETLLPRLKGYLISG-----------SSYARSSVVTAVKFTISDHPQPIDPLLKNCI------GDFLKTLEDPD------------------LNVRRVALVTFNSAAHNKPSLIRDLLDTVLPHLYNETKVRKELIRE--------------VEMGPFKHTVD------DGLDIRKAAFE-----CMYTDSCLDRLDIFEFLNHVG----LKDHYDIKMLTFLM--------LVRLSTLCPSAVLQLDRLVETTKVKANSVKQEFEKQDEKRSAMRAVAALLTPEAEKSPLMSEF-ISSNP

3otvA

1.00

0.21

2.47

wPPAS

------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQLVPGARIANGRYRLLIFHGGVPPLQFWQALDTALDRQVALTFVDPQGVLPDDVLQETLSRTLRLSRIDKPGVARVLDVVHTRAGGLVVAEWIRGGSLQEVADTSPSPVGAIRAMQSLAAAADAAHRAGVALSIDHPSRVRVSIDGDVVLAYPATMPDANPQDDIRGIGASLYALLVNRWPLPEAGVRSGLAPAERDTAGQPIEPADIDRDIPFQISAVAARSVQGDGGIRSASTLLNLMQQATAVADRTEVL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

3otvA

1.00

0.21

2.65

dPPAS2

------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQLVPGARIANGRYRLLIFHGGVPPLQFWQALDTALDRQVALTFVDPQGVLPDDVLQETLSRTLRLSRIDKPGVARVLDVVHTRAGGLVVAEWIRGGSLQEVADTSPSPVGAIRAMQSLAAAADAAHRAGVALSIDHPSRVRVSIDGDVVLAYPATMPDANPQDDIRGIGASLYALLVNRWPLPEAGVRSGLAPAERDTAGQPIEPADIDRDIPFQISAVAARSVQGDGGIRSASTLLNLMQQATAVADRTEVL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

3otvA

1.00

0.21

1.99

PPAS

------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQLVPGARIANGRYRLLIFHGGVPPLQFWQALDTALDRQVALTFVDPQGVLPDDVLQETLSRTLRLSRIDKPGVARVLDVVHTRAGGLVVAEWIRGGSLQEVADTSPSPVGAIRAMQSLAAAADAAHRAGVALSIDHPSRVRVSIDGDVVLAYPATMPDANPQDDIRGIGASLYALLVNRWPLPEAGVRSGLAPAERDTAGQPIEPADIDRDIPFQISAVAARSVQGDGGIRSASTLLNLMQQATAVADRTEVL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

3otvA

1.00

0.21

2.88

Env-PPAS

------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQLVPGARIANGRYRLLIFHGGVPPLQFWQALDTALDRQVALTFVDPQGVLPDDVLQETLSRTLRLSRIDKPGVARVLDVVHTRAGGLVVAEWIRGGSLQEVADTSPSPVGAIRAMQSLAAAADAAHRAGVALSIDHPSRVRVSIDGDVVLAYPATMPDANPQDDIRGIGASLYALLVNRWPLPEAGVRSGLAPAERDTAGQPIEPADIDRDIPFQISAVAARSVQGDGGIRSASTLLNLMQQATAVADRTEVL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

5dlqB

0.10

0.08

0.83

1.47

MUSTER

MAPPSMVSNEQRQHAEHKSKSPFAVCRHILETDYVLFQAATAIMEAVVREWVLLEKGSIESLRTFLLTYVLQKYVREQILLAVAVIVKRGSLDKSIDCKSIFHEVSQLISS-----PTVQTLACSILTALL-----SEFSNCKRVFQEEDLRQIFMLTVGVLQEFSRRENLS---AQMSSVFQRYLALANQVLSWNFLPPTESWREALLDSRVMELFFTVHRKIDMAQDSLQCLAQLASLHGPIFPDEGSQVDYLAHFIEGLLNTINEAVGISSIISNLITVFPRNVLTAIP-SELFSSFVNCLTHLTCSFGRSAALEEVLDKDDMVYMEAYDKLLESWLTLVRFFTQHAVQVFNSYIQCHLAAPDGTRNLTANGVASREDDRDQFSDQLASVGMLGRIAAEH---CMPLLTSLLEERVTRLHGQLQRHQQDNKMLDDLYEDIHWLILVTGYLLA---------DDTQGETPLIPPEIMEYSIKHSSEVDINTTLQILGSPGEKASSIPGYSRTDSVIRLLSAVLRVSEVESRAIRADLTHLPQMGKDIVWFLKRWAKTYLLVDEKLYDQISLPLSTAFGADTEGSQWIIGYLLQKVISNLSVWSSEQDLANDTVQLLVTLVERRERANLVIQCENWWNLAKQFASRSPPLNFLSSPVQRTGGFAHMDTETKQQYWTEVLQPLQQRFLRVINQENFQQMCQQEEVKQEITATLEALCG-----------------IAEATQIDNVAILFNFLMDFLNNCIGLMEVYKNTPETVNLIIE------VFVE------VAHKQICYLGESKAMHLYEACLTLLQVYSKNNLG---------RQRID---------VTAEEEQYQDLLLIMELLTNLLSKV--SAADVVLYGVNLILPLMSQDLLKFPTLCNQYYKLITFICEIFPEKIPQL-PEDLFKSLMYSLEL-----------------------------GMTSMSSEVCQLCLEALTPLALFLATRHFLKLVFDMLVLQNTEMTTAAGEAFYTLVCLYQAEYSELVE----TLLSSQQDPVIYQRLADATASSTPDRKQKMAFLKSLEMANVG---GLL---------------------------------------------------------------------------------------------

4z3nA

0.14

0.05

0.36

1.08

dPPAS

------------FTVAGMFDGSLYKLLLRMALPMFVGMLTQVTYAIADIFWLSHGIIAGVGLVFPVGMGLFAIANGIQIGMGSLLSRAIGMQ-RLDRAQRILSVGIIIALFFAIVITVLGYVYAQPLLRSL--GATKSIIGYATEFYYYSLLTVFSIMLIGVMMGLFQGAGKIMVIMKASLLGALVNIMLDPIMIFVFD-----------FGVKGVALASFLAQLSMVAYFIYTLM----------GSWKIYREFLSVGMAQMLMQLIIAVGIVIYNFFIVRLD-VNAMAAFTLTGRIDYFIITPMLAIATALLTVVGQNWGHGNVTRTLNAYWAAVALAFSIVLVLAVMHIVLAPWMYPLFTR----VVAVSDYAVLQTRIMALALPFVAISLLASEYYQAIGKPWYSVLLTLMRHVISVPVVYLLAIVLEMR---ITGVYFGAMSGTFVAALLAWRLL----------RLSPRLLRWNQEAV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-1.52

Estimated TM-score = 0.53±0.15

Estimated RMSD = 13.1±4.2Å

Download Model 2

C-score=-2.57

Download Model 3

C-score=-3.33

Download Model 4

C-score=-3.27

Download Model 5

C-score=-3.37

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	5ijoJ	0.870	3.36	0.087	0.933
2	4kf7A	0.640	2.84	0.093	0.672
3	5hb4B	0.501	7.40	0.069	0.676
4	4knhA	0.476	5.76	0.068	0.580
5	4ifqA	0.419	6.81	0.054	0.544
6	5ijnD	0.381	6.48	0.054	0.480
7	5dlqB	0.365	8.04	0.063	0.513
8	3gjxA	0.361	7.82	0.045	0.495
9	4i2wA	0.359	6.79	0.063	0.461
10	3m1iC	0.359	7.84	0.053	0.492

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.06	3	5sv1F	III	Rep, Mult	146,149,156
2	0.04	2	4y282	CLA	Rep, Mult	73,74
3	0.04	2	2bptA	III	Rep, Mult	105,108,109,112,113,181,184
4	0.04	2	4ogqB	2WM	Rep, Mult	142,146
5	0.04	2	5a43B	DMU	Rep, Mult	149,157
6	0.04	2	3bz1Z	CLA	Rep, Mult	121,125
7	0.02	1	3prqX	CLA	Rep, Mult	112,119
8	0.02	1	3pyr4	MG	Rep, Mult	67,68
9	0.02	1	1zoyC	EPH	Rep, Mult	39,42
10	0.02	1	2q5dB	III	Rep, Mult	86,89,164
11	0.02	1	1o6oA	III	Rep, Mult	67,70,71,75,137,140,143,144
12	0.02	1	4v1fA	BQ1	Rep, Mult	80,81,84
13	0.02	1	1brrC	ARC	Rep, Mult	336,358,362
14	0.02	1	3ounB	MN	Rep, Mult	730,733
15	0.02	1	2bnwB	NUC	Rep, Mult	34,38
16	0.02	1	3fdoA	MG	Rep, Mult	137,157
17	0.02	1	4fe1L	CLA	Rep, Mult	84,107
18	0.02	1	2g3vB	III	Rep, Mult	119,127,130
19	0.02	1	1o6pB	III	Rep, Mult	104,108,177,180,181

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	2rd0A	0.248	9.20	0.047	0.383	2.7.1.153	NA
2	0.060	2gtqA	0.271	8.35	0.046	0.389	3.4.11.2	32,157
3	0.060	2dqmA	0.281	7.32	0.057	0.374	3.4.11.2	NA
4	0.060	1ea0A	0.259	9.80	0.050	0.414	1.4.1.13	NA
5	0.060	3b9jI	0.067	5.19	0.094	0.079	1.17.1.4,1.17.3.2	NA
6	0.060	3ebgA	0.281	7.73	0.052	0.384	3.4.11.-	NA
7	0.060	2x6fA	0.238	7.51	0.045	0.325	2.7.1.137,2.7.1.153,2.7.1.154	41,48
8	0.060	1fo4A	0.223	9.35	0.030	0.344	1.17.1.4	NA
9	0.060	2e1qA	0.226	9.71	0.046	0.358	1.17.3.2,1.17.1.4	NA
10	0.060	1t3tA	0.258	9.66	0.051	0.409	6.3.5.3	68
11	0.060	2zxqA	0.260	9.14	0.040	0.396	3.2.1.97	77
12	0.060	2q1fA	0.251	7.73	0.040	0.345	4.2.2.21	NA
13	0.060	2vdcA	0.257	9.75	0.031	0.413	1.4.1.13	NA
14	0.060	3b9jJ	0.118	6.48	0.051	0.152	1.17.1.4,1.17.3.2	70
15	0.060	2pdaA	0.240	9.39	0.044	0.368	1.2.7.1	13
16	0.060	2eabA	0.247	7.67	0.033	0.334	3.2.1.63	NA
17	0.060	3ffzA	0.257	9.38	0.033	0.398	3.4.24.69	129
18	0.060	3b9jC	0.164	8.38	0.039	0.236	1.17.3.2,1.17.1.4	NA
19	0.060	2vkzG	0.289	9.67	0.025	0.457	2.3.1.38,3.1.2.14	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.19	0.870	3.36	0.09	0.93	5ijoJ	GO:0005634 GO:0005635 GO:0005643 GO:0006405 GO:0006406 GO:0006409 GO:0006606 GO:0006810 GO:0007077 GO:0010827 GO:0015031 GO:0016020 GO:0016032 GO:0016925 GO:0017056 GO:0019083 GO:0031047 GO:0044611 GO:0051028 GO:0075733 GO:1900034
1	0.07	0.640	2.84	0.09	0.67	4kf7A	GO:0005643 GO:0006406 GO:0006606 GO:0006999 GO:0017056 GO:0031990 GO:0044611
2	0.07	0.501	7.40	0.07	0.68	5hb4B	GO:0005634 GO:0005643 GO:0006810 GO:0015031 GO:0051028
3	0.07	0.482	5.19	0.07	0.57	4knhB	GO:0005634 GO:0005643 GO:0006810 GO:0015031 GO:0051028
4	0.06	0.476	5.76	0.07	0.58	4knhA	GO:0005634 GO:0005643 GO:0006810 GO:0015031 GO:0051028
5	0.06	0.418	6.90	0.05	0.54	4ifqA	GO:0000059 GO:0005634 GO:0005643 GO:0006810 GO:0006999 GO:0015031 GO:0017056 GO:0044611 GO:0046822 GO:0051028
6	0.06	0.381	6.48	0.05	0.48	5ijnD	GO:0000059 GO:0005634 GO:0005635 GO:0005643 GO:0005654 GO:0005737 GO:0006406 GO:0006409 GO:0006810 GO:0006913 GO:0007077 GO:0010827 GO:0015031 GO:0016020 GO:0016032 GO:0016925 GO:0017056 GO:0019083 GO:0031047 GO:0031965 GO:0034399 GO:0044611 GO:0051028 GO:0051292 GO:0075733 GO:1900034
7	0.06	0.166	8.01	0.05	0.23	3qiaA	GO:0000166 GO:0004518 GO:0004519 GO:0005524 GO:0006314 GO:0006754 GO:0006810 GO:0006811 GO:0015991 GO:0015992 GO:0016539 GO:0016787 GO:0016820 GO:0033178 GO:0046034 GO:0090305
8	0.06	0.167	7.04	0.04	0.22	1k9xA	GO:0004180 GO:0004181 GO:0006508 GO:0008233 GO:0008237 GO:0016787 GO:0046872 GO:0050897
9	0.06	0.164	7.86	0.04	0.23	4dozA	GO:0000166 GO:0003723 GO:0005737 GO:0046872 GO:0051607
10	0.06	0.149	6.12	0.07	0.19	4eqfA	GO:0000268 GO:0005052 GO:0005737 GO:0005778 GO:0005829 GO:0016020 GO:0016560 GO:0030425 GO:0031267 GO:0042391 GO:0043235 GO:0043949 GO:0045185
11	0.06	0.157	6.95	0.04	0.21	1bagA	GO:0003824 GO:0004556 GO:0005576 GO:0005975 GO:0008152 GO:0016787 GO:0016798 GO:0043169 GO:0046872
12	0.06	0.142	4.75	0.07	0.16	4f7rD	GO:0019904
13	0.06	0.129	7.09	0.02	0.17	2ptxA	GO:0000015 GO:0000287 GO:0004634 GO:0006096 GO:0016829 GO:0046872
14	0.06	0.131	7.14	0.04	0.17	4hs7A	GO:0005363 GO:0015768
15	0.06	0.112	6.27	0.05	0.14	4q0mA	GO:0004067 GO:0006520
16	0.06	0.118	6.92	0.04	0.16	1w62A	GO:0005576 GO:0005737 GO:0007275 GO:0016020 GO:0016853 GO:0018112
17	0.06	0.133	5.97	0.07	0.16	2pmzC	GO:0003677 GO:0003899 GO:0006351 GO:0016740 GO:0016779
18	0.06	0.098	6.90	0.04	0.13	4wa8A	GO:0000287 GO:0003677 GO:0003824 GO:0004518 GO:0004519 GO:0004527 GO:0006260 GO:0006281 GO:0006974 GO:0008409 GO:0016787 GO:0016788 GO:0017108 GO:0043137 GO:0046872 GO:0090305

Consensus prediction of GO terms

Molecular Function	GO:0005198
GO-Score	0.49
Biological Processes	GO:0017038	GO:0044744	GO:0006405	GO:0071427	GO:1902593	GO:1902583	GO:0032446	GO:0019080	GO:0046794	GO:0051081	GO:0080135	GO:0051049	GO:0051031	GO:1903047	GO:0071431	GO:0032774	GO:0018205	GO:0015758	GO:0034605	GO:0016458	GO:0051028
GO-Score	0.49	0.49	0.49	0.49	0.49	0.38	0.38	0.38	0.38	0.38	0.38	0.38	0.38	0.38	0.38	0.38	0.38	0.38	0.38	0.38	0.34
Cellular Component	GO:0043234	GO:0005643
GO-Score	0.49	0.39

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.