I-TASSER results

Input Sequence in FASTA format

>protein (99 residues)
MEKMSHDPIAADIGTQVSDNALHGVTAGSTALTSVTGLVPAGADEVSAQAATAFTSEGIQ
LLASNASAQDQLHRAGEAVQDVARTYSQIDDGAAGVFAE

Predicted Secondary Structure

Sequence	20 40 60 80 \| \| \| \| MEKMSHDPIAADIGTQVSDNALHGVTAGSTALTSVTGLVPAGADEVSAQAATAFTSEGIQLLASNASAQDQLHRAGEAVQDVARTYSQIDDGAAGVFAE
Prediction	CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHEHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
Conf.Score	988767755777899998876654445654344444445788578899999999999999999999999999999899999999899876655555459
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 \| \| \| \| MEKMSHDPIAADIGTQVSDNALHGVTAGSTALTSVTGLVPAGADEVSAQAATAFTSEGIQLLASNASAQDQLHRAGEAVQDVARTYSQIDDGAAGVFAE
Prediction	855364542134123312532343243443333303223333354133311331244224313344334530453353135125325424553343348
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80

                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHEHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
MEKMSHDPIAADIGTQVSDNALHGVTAGSTALTSVTGLVPAGADEVSAQAATAFTSEGIQLLASNASAQDQLHRAGEAVQDVARTYSQIDDGAAGVFAE

4ke2A

0.17

0.16

0.97

0.79

MUSTER

---MNIDPAARAAAAAAASKAAVTAADAAAAAATIAASAASVAAATAADDAAASIATINAASAAAKSIAAAAAMAAKDTAAAAASAAAAAVASAAKALE

2g38C

0.20

0.15

0.77

0.62

dPPAS

------PEALTVAATEVRRIRDRAIQSDAQVAPMTTAVRPPAADLVSEKAATFLVEYARKYRQTIAAAAVVLEEFAHALTTG-----------------

2g38C

0.21

0.16

0.76

0.79

wdPPAS

-------PALTVAATEVRRIRDRAIQSDAQVAPMTTAVRPPAADLVSEKAATFLVEYARKYRQTIAAAAVVLEEFAHALTTG-----------------

4ke2A

0.16

1.00

0.72

wMUSTER

MAAKDTAAAAASAAAAAVASAAKALETINVKAAYAAATTANTAAAAAAATATTAAAAAAAKATIDNAAAAKAAAVATAVSDAAATAATAAAVAAATLEA

1wa8B

0.17

0.15

0.88

0.84

wPPAS

MTEQQWN-AASAIQGNVTSIHSLLDE----GKQSLTKLAAAGS------GSEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMFA-

2g38C

0.21

0.16

0.76

0.71

dPPAS2

-------PALTVAATEVRRIRDRAIQSDAQVAPMTTAVRPPAADLVSEKAATFLVEYARKYRQTIAAAAVVLEEFAHALTTG-----------------

1wa8B

0.17

0.15

0.88

0.84

PPAS

MTEQQWN-AASAIQGNVTSIHSLLDE----GKQSLTKLAAAGS------GSEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMFA-

3gvmA

0.16

0.14

0.91

0.89

Env-PPAS

MSQIKLTPEELRSSAQKYTAGSQQV---TEVLNLLTQEQ----AVIDENTFDSFEAQFNELSPKITEFAQLLEDINQQLLKVADIIEQTDADIASQI--

5c21A

0.04

1.00

0.67

MUSTER

LTALGAEADTLKTQSSLLQTRLEQTRYQILSRSIELNKLPELSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTILARINRYENLSRVEKSR

3k5bG

0.11

1.00

0.61

dPPAS

GLIKSLAEKEKQLLERLEAAKKEAEERVKRAEAEAKALLEEAEAKAKALEAQYRERERAETEALLARYRERAEAEAKAVREKAARLDEAVALVLKEVLP

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-1.21

Estimated TM-score = 0.56±0.15

Estimated RMSD = 6.4±3.9Å

Download Model 2

C-score=-3.57

Download Model 3

C-score=-3.78

Download Model 4

C-score=-4.41

Download Model 5

C-score=-3.87

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	3k29A	0.815	2.10	0.061	0.970
2	3na7A1	0.806	2.20	0.030	0.980
3	3ok8A	0.780	2.47	0.061	0.970
4	4mh6A	0.774	2.09	0.052	0.960
5	4wheA	0.774	2.40	0.101	1.000
6	2ch7A	0.773	2.22	0.082	0.970
7	1qu7A	0.766	2.22	0.061	0.960
8	3g61A	0.765	2.34	0.083	0.960
9	1ciiA2	0.764	2.16	0.112	0.960
10	3ajwA	0.764	2.29	0.071	0.980

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.08	36	3is7K	HEM	Rep, Mult	25,28,29,32,59,63,66,67,69,70
2	0.08	33	1gu4A	NUC	Rep, Mult	47,48,51,52,54,55,56
3	0.08	36	3u3fD	III	Rep, Mult	22,25,26,28,29,62,65,66,69,72,73
4	0.07	30	4mbeE	III	Rep, Mult	55,58,59,62,63,65,66,69
5	0.07	29	2h7hB	NUC	Rep, Mult	51,52,55,56,58,59,62,63
6	0.06	24	1gu5B	NUC	Rep, Mult	50,51,54,55,57,58,59,61
7	0.04	19	4de6A	ACD	Rep, Mult	21,69,70,73,77
8	0.04	18	1czqA	III	Rep, Mult	75,78,81,85,86
9	0.04	16	2fjcA	FE	Rep, Mult	81,85
10	0.03	11	3wuvD	III	Rep, Mult	61,65,68,71,72,75
11	0.00	1	2psdA	IMD	Rep, Mult	12,35
12	0.00	2	1tygC	PO4	Rep, Mult	13,41,42,61,65,66
13	0.00	1	1i490	III	Rep, Mult	9,13,16,20,23,26,27,30,33,34,41,54,57,61,75
14	0.00	1	1ujw1	III	Rep, Mult	18,22,23,70,71,72,73,74,76,77,79,80,81,85
15	0.00	1	1s4eB	ADP	Rep, Mult	5,41,42,43,46,47,48,51
16	0.00	2	1mneA	POP	Rep, Mult	29,30,31,34,35,36
17	0.00	1	1wuuA	MG	Rep, Mult	45,47
18	0.00	1	1i4d1	III	Rep, Mult	12,15,18,19,22,23,25,26,27,29,30,69,72,76,79,80
19	0.00	1	3l26B	MG	Rep, Mult	38,40,42

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.249	3e7kH	0.489	1.69	0.018	0.556	2.7.11.1	79,84,88
2	0.222	1urfA	0.535	2.84	0.026	0.748	2.7.11.13	17,69,81
3	0.192	1z56A	0.514	1.38	0.014	0.576	6.5.1.1	NA
4	0.173	1wt6B	0.525	1.38	0.085	0.576	2.7.11.1	78
5	0.164	1cxzB	0.579	2.39	0.068	0.727	2.7.11.13	31
6	0.153	2h8nA	0.520	1.40	0.081	0.566	3.5.1.98	78
7	0.150	1vp7B	0.515	2.23	0.040	0.636	3.1.11.6	21,74,76
8	0.146	1joyA	0.452	2.55	0.097	0.606	2.7.13.3	25,30,32
9	0.123	2w5jA	0.520	3.20	0.132	0.737	3.6.3.14	NA
10	0.100	1wu0A	0.523	2.85	0.069	0.717	3.6.3.14	NA
11	0.060	3d4sA	0.593	3.15	0.051	0.869	3.2.1.17	NA
12	0.060	2e9fB	0.647	2.56	0.095	0.818	4.3.2.1	30
13	0.060	2dq3A	0.667	3.06	0.073	0.939	6.1.1.11	24,28
14	0.060	1w07B	0.614	3.15	0.083	0.869	1.3.3.6	NA
15	0.060	3g61A	0.765	2.34	0.083	0.960	3.6.3.44	NA
16	0.060	1wleB	0.626	3.28	0.053	0.899	6.1.1.11	36,57
17	0.060	1u7lA	0.688	2.84	0.102	0.960	3.6.3.14	12,18
18	0.060	1b8fA	0.637	2.51	0.055	0.849	4.3.1.3	NA
19	0.060	1vdkA	0.596	3.31	0.072	0.889	4.2.1.2	NA
20	0.060	2b5uA	0.715	3.03	0.071	1.000	3.1.-.-	NA
21	0.060	1yisA	0.658	2.98	0.075	0.879	4.3.2.2	NA
22	0.060	2fonB	0.612	3.24	0.103	0.869	1.3.3.6	NA
23	0.060	1j3uA	0.603	2.84	0.022	0.788	4.3.1.1	30
24	0.060	1q5nA	0.620	3.46	0.074	0.889	5.5.1.2	66
25	0.060	1clqA	0.620	3.40	0.071	0.919	2.7.7.7	38,52
26	0.060	3errA	0.610	3.64	0.071	0.970	6.1.1.11	NA
27	0.060	3no9A	0.604	2.68	0.044	0.768	4.2.1.2	28,65
28	0.060	1eiyA	0.624	2.66	0.073	0.818	6.1.1.20	NA
29	0.060	3gtdA	0.597	3.01	0.033	0.788	4.2.1.2	29

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.36	0.503	1.46	0.06	0.56	1ysaC	GO:0000122 GO:0000790 GO:0000978 GO:0000981 GO:0001080 GO:0001084 GO:0001135 GO:0001190 GO:0001191 GO:0003677 GO:0003682 GO:0003700 GO:0005634 GO:0005667 GO:0006351 GO:0006355 GO:0006366 GO:0008652 GO:0010691 GO:0042802 GO:0043565 GO:0045899 GO:0060261 GO:1903833
1	0.29	0.504	1.24	0.13	0.56	1kqlA	GO:0000122 GO:0000790 GO:0000978 GO:0000981 GO:0001080 GO:0001084 GO:0001135 GO:0001190 GO:0001191 GO:0003677 GO:0003682 GO:0003700 GO:0005634 GO:0005667 GO:0006351 GO:0006355 GO:0006366 GO:0008652 GO:0010691 GO:0042802 GO:0043565 GO:0045899 GO:0060261 GO:1903833
2	0.28	0.460	1.51	0.13	0.51	1gk6A	GO:0000122 GO:0000790 GO:0000978 GO:0000981 GO:0001080 GO:0001084 GO:0001135 GO:0001190 GO:0001191 GO:0001948 GO:0003677 GO:0003682 GO:0003700 GO:0003725 GO:0005198 GO:0005200 GO:0005212 GO:0005634 GO:0005667 GO:0005737 GO:0005777 GO:0005829 GO:0005856 GO:0005882 GO:0005886 GO:0005925 GO:0006351 GO:0006355 GO:0006366 GO:0006928 GO:0008022 GO:0008652 GO:0010628 GO:0010691 GO:0010977 GO:0014002 GO:0016032 GO:0030049 GO:0031012 GO:0031252 GO:0042802 GO:0042995 GO:0043005 GO:0043565 GO:0045103 GO:0045109 GO:0045111 GO:0045899 GO:0060020 GO:0060261 GO:0060395 GO:0070062 GO:0070307 GO:0097110 GO:1903833 GO:1990254
3	0.26	0.750	2.35	0.07	0.96	3g67A	GO:0004871 GO:0007165 GO:0016020
4	0.24	0.672	2.00	0.04	0.81	3k29A	GO:0042802
5	0.23	0.774	2.40	0.10	1.00	4wheA	GO:0005543 GO:0005737 GO:0005829 GO:0005886 GO:0009271 GO:0009408 GO:0016020 GO:0031234 GO:0042802 GO:0043433 GO:0060187
6	0.22	0.712	2.61	0.11	0.95	2vrzA	GO:0005576 GO:0009405
7	0.17	0.780	2.23	0.04	0.98	1y2oA	GO:0001726 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005913 GO:0007009 GO:0007409 GO:0008022 GO:0008093 GO:0008286 GO:0008360 GO:0009617 GO:0014069 GO:0015629 GO:0016020 GO:0016358 GO:0030141 GO:0030165 GO:0030175 GO:0030838 GO:0032956 GO:0038096 GO:0042802 GO:0042995 GO:0043005 GO:0043025 GO:0043197 GO:0048010 GO:0048167 GO:0051017 GO:0051764 GO:0061003 GO:0070062 GO:0070064 GO:0097481 GO:0098609 GO:0098641 GO:2000251
8	0.16	0.780	2.47	0.06	0.97	3ok8A	GO:0005543 GO:0005829 GO:0005886 GO:0007009 GO:0008093 GO:0008286 GO:0008289 GO:0012506 GO:0015629 GO:0016020 GO:0030054 GO:0030659 GO:0030838 GO:0031410 GO:0044291 GO:0051017 GO:0051764 GO:0061024 GO:0071439 GO:2000251
9	0.16	0.713	2.38	0.08	0.96	3zx6A	GO:0004871 GO:0004888 GO:0005886 GO:0005887 GO:0006935 GO:0007165 GO:0016020 GO:0016021 GO:0043200 GO:0043424 GO:0046872 GO:0048870
10	0.14	0.773	2.22	0.08	0.97	2ch7A	GO:0004871 GO:0005886 GO:0006935 GO:0007165 GO:0016020 GO:0016021
11	0.14	0.583	2.78	0.01	0.78	1eboF	GO:0005576 GO:0016020 GO:0016021 GO:0016032 GO:0019012 GO:0019031 GO:0019062 GO:0020002 GO:0030683 GO:0033644 GO:0039502 GO:0039503 GO:0039587 GO:0039654 GO:0039663 GO:0046718 GO:0055036 GO:0075509 GO:0075512
12	0.12	0.496	1.76	0.03	0.58	2npsD	GO:0000139 GO:0005484 GO:0005769 GO:0005794 GO:0005802 GO:0005829 GO:0005886 GO:0006810 GO:0006886 GO:0006906 GO:0007032 GO:0015031 GO:0016020 GO:0016021 GO:0016192 GO:0019905 GO:0030136 GO:0031201 GO:0032456 GO:0032588 GO:0032880 GO:0042147 GO:0043195 GO:0045335 GO:0048193 GO:0048278 GO:0048471 GO:0090161 GO:1903827
13	0.11	0.562	2.71	0.02	0.80	2oszA	GO:0005487 GO:0005634 GO:0005635 GO:0005643 GO:0006810 GO:0006913 GO:0008139 GO:0015031 GO:0016020 GO:0031965 GO:0042306 GO:0043234 GO:0051028 GO:0051260 GO:0051290 GO:0051291 GO:0070208
14	0.11	0.555	3.05	0.05	0.81	1envA	GO:0000122 GO:0000790 GO:0000978 GO:0000981 GO:0001080 GO:0001084 GO:0001135 GO:0001190 GO:0001191 GO:0002223 GO:0003677 GO:0003682 GO:0003700 GO:0005198 GO:0005634 GO:0005667 GO:0006351 GO:0006355 GO:0006366 GO:0008652 GO:0010691 GO:0016020 GO:0016021 GO:0016032 GO:0019012 GO:0019031 GO:0019062 GO:0019064 GO:0019082 GO:0020002 GO:0030683 GO:0033644 GO:0039654 GO:0039663 GO:0042802 GO:0043565 GO:0044174 GO:0044175 GO:0045899 GO:0046718 GO:0055036 GO:0060261 GO:0075509 GO:0075512 GO:1903833
15	0.08	0.477	2.24	0.06	0.59	4bl6C	GO:0003729 GO:0005737 GO:0005794 GO:0005829 GO:0005856 GO:0006810 GO:0007275 GO:0007293 GO:0007294 GO:0007309 GO:0007310 GO:0007312 GO:0007314 GO:0008103 GO:0008298 GO:0016325 GO:0017137 GO:0019233 GO:0030100 GO:0030154 GO:0030669 GO:0030727 GO:0032050 GO:0045502 GO:0048477 GO:0048488 GO:0050658 GO:0051028 GO:0070727 GO:2000302 GO:2000370
16	0.07	0.616	3.41	0.03	0.88	3v47C	GO:0005198 GO:0005576 GO:0009288 GO:0009420 GO:0071973
17	0.07	0.617	3.06	0.06	0.87	4uxvA	GO:0000921 GO:0005886 GO:0005940 GO:0007049 GO:0016020 GO:0016021 GO:0051301 GO:0051781
18	0.07	0.634	2.18	0.05	0.81	1qsdA	GO:0005737 GO:0005856 GO:0005874 GO:0007021 GO:0007023 GO:0015631 GO:0048487
19	0.07	0.525	2.25	0.04	0.67	2c2jA	GO:0005737 GO:0006879 GO:0006950 GO:0008199 GO:0016491 GO:0046872 GO:0055114
20	0.07	0.540	3.56	0.08	0.83	2jesA	GO:0019012 GO:0019028 GO:0019076 GO:0046718 GO:0046729
21	0.06	0.516	4.02	0.09	0.87	5a20A	GO:0019012 GO:0019028 GO:0019076 GO:0046718 GO:0046729
22	0.06	0.392	4.27	0.04	0.67	4k2nA	GO:0003824 GO:0008152
23	0.06	0.457	2.71	0.03	0.62	4ehiB	GO:0003824 GO:0003937 GO:0004643 GO:0006164 GO:0006189 GO:0008152 GO:0016740 GO:0016787

Consensus prediction of GO terms

Molecular Function	GO:0042802	GO:0000978	GO:0001084	GO:0003682	GO:0001190	GO:0001135	GO:0000981	GO:0097367	GO:0003723	GO:0019215	GO:0005198
GO-Score	0.75	0.67	0.67	0.67	0.67	0.67	0.67	0.55	0.55	0.55	0.55
Biological Processes	GO:0010691	GO:0008652	GO:0045899	GO:0001080	GO:1903833	GO:0044403	GO:0045665	GO:0002064	GO:0007178	GO:0033275	GO:0048708	GO:0045104	GO:0044764	GO:0031345	GO:0010975	GO:0070306	GO:0021782	GO:0006936
GO-Score	0.67	0.67	0.67	0.67	0.67	0.55	0.55	0.55	0.55	0.55	0.55	0.55	0.55	0.55	0.55	0.55	0.55	0.55
Cellular Component	GO:0000790	GO:0005667	GO:0005924	GO:0099513	GO:0042579	GO:0071944	GO:0097458	GO:0031988	GO:0042995	GO:1903561	GO:0016020
GO-Score	0.67	0.67	0.55	0.55	0.55	0.55	0.55	0.55	0.55	0.55	0.41

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv3872

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]