Threading Zmax Znorm MUSTER 5.98 1.03 dPPAS 8.90 0.96 wdPPAS 7.83 0.84 wMUSTER 6.30 1.09 wPPAS 5.19 0.74 dPPAS2 15.00 1.43 PPAS 6.33 0.90 Env-PPAS 7.38 0.92 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=11538) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -1.44 0.54+-0.15 6.0+-3.7 7844 0.239 model2 -3.05 1842 0.048 model3 -2.22 3040 0.110 model4 -2.58 2501 0.076 model5 -3.87 613 0.021 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).