Threading Zmax Znorm MUSTER 4.89 0.84 dPPAS 7.35 0.79 wdPPAS 8.03 0.86 wMUSTER 5.93 1.02 wPPAS 9.21 1.31 dPPAS2 14.03 1.34 PPAS 7.16 1.02 Env-PPAS 6.60 0.83 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=20200) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -3.97 0.29+-0.09 16.1+-3.1 2896 0.019 model2 -3.10 2453 0.045 model3 -4.99 961 0.007 model4 -4.81 1292 0.008 model5 -5.00 692 0.004 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).