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I-TASSER results for job id Rv3843c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

 Input Sequence in FASTA format
 Predicted Secondary Structure
 Predicted Solvent Accessibility
 Predicted Normalized B-facotr
 Top 10 threading templates used by I-TASSER
 Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)
 Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)


 Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)


  Ligand binding sites

Rank C-score Cluster
size
PDB
Hit
Lig
Name
Download
Complex
Ligand Binding Site Residues
10.06 4 1lv3A ZN Rep, Mult 5,8,22,25
20.06 4 2y00B 2CV Rep, Mult 261,265,278,281,285,288
30.04 3 3fyeD HEA Rep, Mult 219,223
40.04 3 4ntjA CLR Rep, Mult 191,256,259,260,263
50.03 2 4ezcA BGC Rep, Mult 250,251
60.03 2 2y00B Y01 Rep, Mult 176,177,180,181,184
70.03 2 3fyiA DMU Rep, Mult 243,247,297,301
80.03 2 2y00A 2CV Rep, Mult 285,292,296
90.01 1 2ycxB SOG Rep, Mult 166,170,177,178,182
100.01 1 2ycyB SOG Rep, Mult 188,191,218,256,257,260
110.01 1 1brrC ARC Rep, Mult 261,284,288
120.01 1 2ycxA SOG Rep, Mult 188,249,252,253,256,257
130.01 1 2axtI CLA Rep, Mult 187,191,198
140.01 1 4bmoA FMN Rep, Mult 123,126,300
150.01 1 1zavA III Rep, Mult 300,307
160.01 1 1rwtB CLA Rep, Mult 186,189
170.01 1 2y00B 2CV Rep, Mult 251,254,298
180.01 1 3oe6A OLC Rep, Mult 184,187,188,191,219
190.01 1 3s7bA BU3 Rep, Mult 24,42
200.01 1 2ycxB SOG Rep, Mult 188,191,192,195,218

Download the all possible binding ligands and detailed prediction summary.
Download the templates clustering results.
(a)C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)Cluster size is the total number of templates in a cluster.
(c)Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column.
Mult is the complex structures with all potential binding ligands in the cluster.

  Enzyme Commission (EC) numbers and active sites

RankCscoreECPDB
Hit
TM-scoreRMSDaIDENaCovEC NumberActive Site Residues
10.0603ee4A0.3764.950.0580.5121.17.4.1NA
20.0601n1hA0.3866.770.0400.6642.7.7.48182
30.0603g61A0.4126.070.0610.6113.6.3.44NA
40.0601yfmA0.3795.960.0430.5854.2.1.2NA
50.0601h0hA0.3867.170.0270.6841.2.1.2NA
60.0601syyA0.3865.420.0290.5531.17.4.1NA
70.0602b3xA0.3096.890.0540.5474.2.1.3NA
80.0601biqB0.4035.300.0550.5671.17.4.1NA
90.0602ow6A0.3946.110.0390.6143.2.1.114238
100.0601jnrA0.4036.430.0520.6611.8.99.2NA
110.0605acnA0.3696.690.0430.6264.2.1.3NA
120.0601t3tA0.3796.870.0530.6556.3.5.3NA
130.0602o8rA0.3746.850.0590.6552.7.4.1186,299
140.0603bkkA0.3836.810.0510.6583.4.15.1NA
150.0602aj4A0.3846.520.0420.6492.7.1.6NA
160.0602iukA0.4126.520.0400.6811.13.11.12NA
170.0601mhyB0.3746.320.0330.5911.14.13.25185
180.0603e04D0.3826.230.0630.6024.2.1.2296
190.0603dy5A0.3886.760.0470.6551.13.11.40,4.2.1.92NA

(a)CscoreEC is the confidence score for the EC number prediction. CscoreEC values range in between [0-1];
where a higher score indicates a more reliable EC number prediction.
(b)TM-score is a measure of global structural similarity between query and template protein.
(c)RMSDa is the RMSD between residues that are structurally aligned by TM-align.
(d)IDENa is the percentage sequence identity in the structurally aligned region.
(e)Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided
by length of the query protein.

  Gene Ontology (GO) terms

Homologous GO templates in PDB 
RankCscoreGOTM-scoreRMSDaIDENaCovPDB HitAssociated GO Terms
00.080.4294.970.090.591f88B GO:0000139 GO:0001750 GO:0001917 GO:0004871 GO:0004930 GO:0005085 GO:0005794 GO:0005886 GO:0005887 GO:0005911 GO:0006468 GO:0007165 GO:0007186 GO:0007601 GO:0007602 GO:0007603 GO:0008020 GO:0009416 GO:0009583 GO:0009881 GO:0016020 GO:0016021 GO:0016038 GO:0016056 GO:0018298 GO:0022400 GO:0042622 GO:0043547 GO:0045494 GO:0046872 GO:0050896 GO:0050953 GO:0060041 GO:0060342 GO:0071482 GO:0097381
10.070.5125.590.070.784n4wA GO:0000122 GO:0001503 GO:0001570 GO:0001649 GO:0001701 GO:0001708 GO:0001755 GO:0001947 GO:0002052 GO:0002053 GO:0003007 GO:0003140 GO:0003323 GO:0004871 GO:0004888 GO:0004930 GO:0005113 GO:0005506 GO:0005737 GO:0005794 GO:0005886 GO:0005901 GO:0005929 GO:0007165 GO:0007166 GO:0007186 GO:0007224 GO:0007228 GO:0007275 GO:0007368 GO:0007371 GO:0007389 GO:0007417 GO:0007494 GO:0008144 GO:0008284 GO:0009055 GO:0009952 GO:0009953 GO:0010468 GO:0010628 GO:0010629 GO:0016020 GO:0016021 GO:0017147 GO:0020037 GO:0021542 GO:0021696 GO:0021794 GO:0021904 GO:0021910 GO:0021938 GO:0021953 GO:0021987 GO:0022900 GO:0030666 GO:0030857 GO:0031069 GO:0034504 GO:0035264 GO:0035567 GO:0040018 GO:0042307 GO:0042475 GO:0042597 GO:0042813 GO:0042995 GO:0043066 GO:0043231 GO:0043392 GO:0045880 GO:0045892 GO:0045893 GO:0045944 GO:0046622 GO:0046872 GO:0048143 GO:0048468 GO:0048565 GO:0048568 GO:0048589 GO:0048741 GO:0048853 GO:0048873 GO:0050679 GO:0050821 GO:0051451 GO:0051799 GO:0060070 GO:0060170 GO:0060248 GO:0060413 GO:0060644 GO:0060684 GO:0061053 GO:0061113 GO:0070062 GO:0070986 GO:0071397 GO:0072001 GO:0072285 GO:0072372 GO:0090190 GO:0097542 GO:2000036 GO:2000826
20.070.4655.540.070.684qimA GO:0000122 GO:0001503 GO:0001570 GO:0001649 GO:0001701 GO:0001708 GO:0001755 GO:0001947 GO:0002052 GO:0002053 GO:0003007 GO:0003140 GO:0003323 GO:0004871 GO:0004888 GO:0004930 GO:0005113 GO:0005506 GO:0005737 GO:0005794 GO:0005886 GO:0005901 GO:0005929 GO:0007165 GO:0007166 GO:0007186 GO:0007224 GO:0007228 GO:0007275 GO:0007368 GO:0007371 GO:0007389 GO:0007417 GO:0007494 GO:0008144 GO:0008284 GO:0009055 GO:0009952 GO:0009953 GO:0010468 GO:0010628 GO:0010629 GO:0016020 GO:0016021 GO:0017147 GO:0020037 GO:0021542 GO:0021696 GO:0021794 GO:0021904 GO:0021910 GO:0021938 GO:0021953 GO:0021987 GO:0022900 GO:0030666 GO:0030857 GO:0031069 GO:0034504 GO:0035264 GO:0035567 GO:0040018 GO:0042307 GO:0042475 GO:0042597 GO:0042813 GO:0042995 GO:0043066 GO:0043231 GO:0043392 GO:0045880 GO:0045892 GO:0045893 GO:0045944 GO:0046622 GO:0046872 GO:0048143 GO:0048468 GO:0048565 GO:0048568 GO:0048589 GO:0048741 GO:0048853 GO:0048873 GO:0050679 GO:0050821 GO:0051451 GO:0051799 GO:0055114 GO:0060070 GO:0060170 GO:0060248 GO:0060413 GO:0060644 GO:0060684 GO:0061053 GO:0061113 GO:0070062 GO:0070986 GO:0071397 GO:0072001 GO:0072285 GO:0072372 GO:0090190 GO:0097542 GO:2000036 GO:2000826
30.070.4585.850.110.684yayA GO:0001558 GO:0001596 GO:0001822 GO:0002018 GO:0002034 GO:0003081 GO:0004871 GO:0004930 GO:0004945 GO:0005506 GO:0005622 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0007200 GO:0007204 GO:0007266 GO:0009055 GO:0010744 GO:0010873 GO:0016020 GO:0016021 GO:0019229 GO:0019722 GO:0020037 GO:0022900 GO:0031711 GO:0032270 GO:0032430 GO:0033864 GO:0034374 GO:0035813 GO:0038166 GO:0042127 GO:0042312 GO:0042597 GO:0046872 GO:0046982 GO:0050727 GO:0050729 GO:0051482 GO:0055114 GO:0060326 GO:0086097 GO:2000379
40.070.4595.340.060.662ziyA GO:0004871 GO:0004930 GO:0007165 GO:0007186 GO:0007601 GO:0007602 GO:0009881 GO:0016020 GO:0016021 GO:0018298 GO:0050896
50.070.4455.350.090.635dhhB GO:0001626 GO:0001934 GO:0004871 GO:0004930 GO:0004985 GO:0005506 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0007193 GO:0007204 GO:0007218 GO:0007268 GO:0007600 GO:0007610 GO:0008022 GO:0009055 GO:0016020 GO:0016021 GO:0016023 GO:0019233 GO:0020037 GO:0022900 GO:0030817 GO:0030818 GO:0031410 GO:0032355 GO:0035810 GO:0038003 GO:0042597 GO:0042755 GO:0042923 GO:0043005 GO:0044849 GO:0045776 GO:0046872 GO:0051930 GO:0060454 GO:1901386 GO:1904058 GO:1904059
60.070.4325.320.070.614xnwC GO:0001934 GO:0001973 GO:0004871 GO:0004872 GO:0004930 GO:0005506 GO:0005524 GO:0005739 GO:0005829 GO:0005886 GO:0005887 GO:0007165 GO:0007166 GO:0007186 GO:0007193 GO:0007200 GO:0007204 GO:0007568 GO:0007596 GO:0007599 GO:0008347 GO:0009055 GO:0009612 GO:0009986 GO:0010469 GO:0010700 GO:0016020 GO:0016021 GO:0016323 GO:0016324 GO:0019233 GO:0023019 GO:0030168 GO:0030425 GO:0031686 GO:0032962 GO:0035589 GO:0042060 GO:0042312 GO:0042755 GO:0043270 GO:0043531 GO:0044297 GO:0045028 GO:0045031 GO:0045032 GO:0045211 GO:0045944 GO:0046872 GO:0046887 GO:0046982 GO:0051100 GO:0055114 GO:0060406 GO:0070374 GO:0070848 GO:0071407 GO:0072659 GO:0090075 GO:0097110 GO:0097481
70.070.4555.250.090.645dgyA GO:0000139 GO:0001523 GO:0001750 GO:0001917 GO:0002046 GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0005794 GO:0005886 GO:0005887 GO:0005911 GO:0006468 GO:0007165 GO:0007186 GO:0007601 GO:0007602 GO:0007603 GO:0008020 GO:0008152 GO:0009253 GO:0009416 GO:0009583 GO:0009585 GO:0009881 GO:0016020 GO:0016021 GO:0016038 GO:0016056 GO:0016787 GO:0016798 GO:0016918 GO:0016998 GO:0018298 GO:0019076 GO:0019835 GO:0022400 GO:0030430 GO:0030507 GO:0030660 GO:0030867 GO:0042622 GO:0042742 GO:0045494 GO:0046872 GO:0050896 GO:0050953 GO:0051219 GO:0060041 GO:0060170 GO:0060342 GO:0071482 GO:0097381
80.070.4535.020.080.634bwbA GO:0001659 GO:0003085 GO:0003254 GO:0004871 GO:0004930 GO:0005737 GO:0005739 GO:0005783 GO:0005794 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0007218 GO:0007612 GO:0008344 GO:0009898 GO:0009986 GO:0014049 GO:0014054 GO:0016020 GO:0016021 GO:0016492 GO:0030424 GO:0030425 GO:0032280 GO:0033993 GO:0042803 GO:0043025 GO:0043065 GO:0043066 GO:0043195 GO:0043197 GO:0043198 GO:0043204 GO:0043576 GO:0043679 GO:0044309 GO:0045121 GO:0045202 GO:0046982 GO:0047485 GO:0050965 GO:0051280 GO:0051281 GO:0051930 GO:0060732 GO:0070779 GO:0071545 GO:0090238 GO:0097151 GO:0098900 GO:1990123 GO:2001259
90.070.4385.910.060.664or2B GO:0000186 GO:0000187 GO:0004871 GO:0004930 GO:0005506 GO:0005634 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0007205 GO:0007216 GO:0007268 GO:0007626 GO:0008066 GO:0009055 GO:0014069 GO:0016020 GO:0016021 GO:0019233 GO:0020037 GO:0022900 GO:0030425 GO:0038037 GO:0038038 GO:0038042 GO:0042597 GO:0043005 GO:0043408 GO:0046872 GO:0051482 GO:0051930 GO:0051966 GO:0055114 GO:0071257
100.070.4554.630.080.602ydvA GO:0001609 GO:0001973 GO:0004871 GO:0004930 GO:0005886 GO:0005887 GO:0006171 GO:0006909 GO:0006915 GO:0006954 GO:0006968 GO:0007165 GO:0007186 GO:0007188 GO:0007267 GO:0007417 GO:0007596 GO:0007600 GO:0008015 GO:0010579 GO:0016020 GO:0016021 GO:0019899 GO:0042802 GO:0044267
110.070.4505.140.070.624n6hA GO:0000060 GO:0004871 GO:0004930 GO:0004985 GO:0005506 GO:0005737 GO:0005886 GO:0005887 GO:0006955 GO:0007165 GO:0007186 GO:0007187 GO:0007193 GO:0007200 GO:0007218 GO:0007268 GO:0008344 GO:0009055 GO:0010629 GO:0016020 GO:0016021 GO:0019233 GO:0020037 GO:0022900 GO:0031226 GO:0031982 GO:0032460 GO:0032590 GO:0032793 GO:0033138 GO:0038003 GO:0038046 GO:0042597 GO:0042755 GO:0042923 GO:0043005 GO:0043679 GO:0045121 GO:0045211 GO:0046872 GO:0051881 GO:0051924 GO:0051930 GO:0055114 GO:0071363 GO:0071456 GO:0097237
120.060.4335.520.070.634ldeA GO:0001666 GO:0001889 GO:0001965 GO:0001993 GO:0002024 GO:0002025 GO:0002028 GO:0002032 GO:0002086 GO:0003059 GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0004935 GO:0004941 GO:0005634 GO:0005737 GO:0005764 GO:0005768 GO:0005769 GO:0005886 GO:0005887 GO:0005901 GO:0006898 GO:0006940 GO:0007165 GO:0007166 GO:0007171 GO:0007186 GO:0007188 GO:0007189 GO:0007190 GO:0007267 GO:0007565 GO:0007568 GO:0008144 GO:0008152 GO:0008179 GO:0008284 GO:0008306 GO:0008333 GO:0009253 GO:0009409 GO:0010765 GO:0015459 GO:0016020 GO:0016021 GO:0016324 GO:0016525 GO:0016787 GO:0016798 GO:0016998 GO:0019076 GO:0019835 GO:0019899 GO:0030279 GO:0030424 GO:0030425 GO:0030430 GO:0030501 GO:0031398 GO:0031649 GO:0031713 GO:0032403 GO:0032570 GO:0032781 GO:0032809 GO:0033574 GO:0035240 GO:0035249 GO:0035255 GO:0035811 GO:0040015 GO:0042060 GO:0042312 GO:0042383 GO:0042742 GO:0042803 GO:0043065 GO:0043197 GO:0043231 GO:0043235 GO:0043268 GO:0043410 GO:0043627 GO:0044849 GO:0045453 GO:0045823 GO:0045909 GO:0045944 GO:0045986 GO:0048633 GO:0050728 GO:0050873 GO:0051379 GO:0051380 GO:0051924 GO:0051930 GO:0060079 GO:0071456 GO:0071548 GO:0071867 GO:0071880 GO:0090331 GO:0097421 GO:1901098 GO:1904504 GO:1904925
130.060.4354.820.050.594l6rA GO:0004871 GO:0004888 GO:0004930 GO:0004967 GO:0005085 GO:0005506 GO:0005768 GO:0005886 GO:0005887 GO:0006091 GO:0006887 GO:0007165 GO:0007166 GO:0007186 GO:0007188 GO:0007189 GO:0007584 GO:0008217 GO:0009055 GO:0009755 GO:0016020 GO:0016021 GO:0017046 GO:0020037 GO:0022900 GO:0042593 GO:0042594 GO:0042597 GO:0043547 GO:0046872 GO:0055114 GO:0070873 GO:0071377
140.060.4405.010.110.615c1mA GO:0001965 GO:0002438 GO:0004871 GO:0004930 GO:0004979 GO:0004985 GO:0005245 GO:0005737 GO:0005829 GO:0005886 GO:0005887 GO:0005925 GO:0007165 GO:0007186 GO:0007191 GO:0007193 GO:0007194 GO:0007200 GO:0007204 GO:0007218 GO:0007268 GO:0007626 GO:0008022 GO:0009314 GO:0016020 GO:0016021 GO:0019233 GO:0019904 GO:0030425 GO:0030818 GO:0031005 GO:0031635 GO:0031681 GO:0032094 GO:0032100 GO:0032496 GO:0032590 GO:0032839 GO:0033554 GO:0038003 GO:0038047 GO:0042060 GO:0042220 GO:0042383 GO:0042755 GO:0042923 GO:0043005 GO:0043204 GO:0043278 GO:0043950 GO:0043951 GO:0044849 GO:0045019 GO:0045121 GO:0045429 GO:0045471 GO:0048149 GO:0050769 GO:0051481 GO:0051930 GO:0060079 GO:0061358 GO:0070374 GO:0070588 GO:0070848 GO:0071315 GO:0098794 GO:2000310
150.060.4184.960.090.563rzeA GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0004969 GO:0005654 GO:0005737 GO:0005886 GO:0005887 GO:0006954 GO:0007165 GO:0007186 GO:0007200 GO:0007613 GO:0008152 GO:0008542 GO:0009253 GO:0016020 GO:0016021 GO:0016787 GO:0016798 GO:0016998 GO:0019076 GO:0019229 GO:0019835 GO:0030430 GO:0032962 GO:0042742 GO:0043114 GO:0045907 GO:0048016 GO:0048167 GO:0048245 GO:0050804 GO:0071420
160.060.4314.680.090.574mqsA GO:0004871 GO:0004930 GO:0005886 GO:0005887 GO:0006940 GO:0007165 GO:0007186 GO:0007187 GO:0007188 GO:0007197 GO:0007207 GO:0007213 GO:0007271 GO:0007399 GO:0008016 GO:0008144 GO:0009615 GO:0016020 GO:0016021 GO:0016907 GO:0030054 GO:0030425 GO:0032279 GO:0032280 GO:0043025 GO:0043679 GO:0045202 GO:0045211
170.060.4525.150.080.634z34A GO:0000187 GO:0001965 GO:0004871 GO:0004930 GO:0005506 GO:0005543 GO:0005737 GO:0005768 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0007193 GO:0007202 GO:0007204 GO:0007420 GO:0008289 GO:0008360 GO:0009055 GO:0009986 GO:0010942 GO:0010977 GO:0014003 GO:0016020 GO:0016021 GO:0020037 GO:0021549 GO:0021554 GO:0022008 GO:0022038 GO:0022900 GO:0030139 GO:0030165 GO:0030818 GO:0032060 GO:0035025 GO:0035727 GO:0042552 GO:0042597 GO:0043005 GO:0043025 GO:0043065 GO:0043123 GO:0043197 GO:0043198 GO:0043410 GO:0046872 GO:0051482 GO:0051496 GO:0055114 GO:0060326 GO:0060999 GO:0070915 GO:0071453 GO:0071673 GO:1904566
180.060.4445.410.090.623v2yA GO:0001525 GO:0001664 GO:0001955 GO:0003245 GO:0003376 GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0005768 GO:0005829 GO:0005886 GO:0006935 GO:0007155 GO:0007165 GO:0007186 GO:0007193 GO:0007420 GO:0008152 GO:0008284 GO:0009253 GO:0009897 GO:0016020 GO:0016021 GO:0016477 GO:0016787 GO:0016798 GO:0016998 GO:0019076 GO:0019226 GO:0019835 GO:0030032 GO:0030155 GO:0030182 GO:0030335 GO:0030430 GO:0030500 GO:0031226 GO:0031532 GO:0038036 GO:0042742 GO:0043547 GO:0045121 GO:0045124 GO:0045446 GO:0045944 GO:0046625 GO:0048661 GO:0050927 GO:0051482 GO:0051497 GO:0061384 GO:0072678


Consensus prediction of GO terms
 
Molecular Function GO:0004888 GO:0046906 GO:0046914
GO-Score 0.59 0.37 0.37
Biological Processes GO:0007154 GO:0051716 GO:0044700 GO:0050794 GO:0006091 GO:0055114
GO-Score 0.59 0.59 0.59 0.59 0.37 0.37
Cellular Component GO:0071944 GO:0031224 GO:0012505 GO:0044444 GO:0043231
GO-Score 0.49 0.47 0.39 0.39 0.39

(a)CscoreGO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)TM-score is a measure of global structural similarity between query and template protein.
(c)RMSDa is the RMSD between residues that are structurally aligned by TM-align.
(d)IDENa is the percentage sequence identity in the structurally aligned region.
(e)Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on CscoreGO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]



Please cite the following articles when you use the I-TASSER server:
1. J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2. J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.