I-TASSER results

I-TASSER results for job id Rv3839

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (258 residues)
MPPLTSLAPTTAERIRSACARAGGALLVVEREDPVPVPIHHLLYDGSFAVAVPVDRGEVS
GSQALLELTDYAPLPVREPVRSLVWIRGCLHQIPPAELVETLDLIATDNPNPALLQVETP
RPGPADAAETRYTMQRLEIESVVVTDATGAEPVTVADLLAARPDPFCEIESTLLWHLATA
HDDVVARLVSRLPAPLRRGQIRPLGLDRYGVRFRIEARDGDRDIRLPFHKPVDDMTGLSQ
AIRVLMGCPFRNGLRARR

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 \| \| \| \| \| \| \| \| \| \| \| \| MPPLTSLAPTTAERIRSACARAGGALLVVEREDPVPVPIHHLLYDGSFAVAVPVDRGEVSGSQALLELTDYAPLPVREPVRSLVWIRGCLHQIPPAELVETLDLIATDNPNPALLQVETPRPGPADAAETRYTMQRLEIESVVVTDATGAEPVTVADLLAARPDPFCEIESTLLWHLATAHDDVVARLVSRLPAPLRRGQIRPLGLDRYGVRFRIEARDGDRDIRLPFHKPVDDMTGLSQAIRVLMGCPFRNGLRARR
Prediction	CCCCCCCCCCHHHHHHHHHHHCCCEEEEHCCCCCCCCCCEEHCCCCCEEEEHCCCCCCCCCCCCCEEEEEHCCCCCCCCCCEEEEEEEEEEHCCHHHHHHHHHHHHHHCCCCCCHCCCCCCCCCCCCCCCCEEEEEEEEEEEEEHCCCCEEEHCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHCCCCEEEEEHCCCCEEEEHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
Conf.Score	998888999888999999997796799966899876664787589987999758887767876555666556888888865689999988878978999999999998898644345676555544566666899999989999868756887899877599985578999999999988799999999997888887757999875788589999589758999757866899999999999999755555787889
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 \| \| \| \| \| \| \| \| \| \| \| \| MPPLTSLAPTTAERIRSACARAGGALLVVEREDPVPVPIHHLLYDGSFAVAVPVDRGEVSGSQALLELTDYAPLPVREPVRSLVWIRGCLHQIPPAELVETLDLIATDNPNPALLQVETPRPGPADAAETRYTMQRLEIESVVVTDATGAEPVTVADLLAARPDPFCEIESTLLWHLATAHDDVVARLVSRLPAPLRRGQIRPLGLDRYGVRFRIEARDGDRDIRLPFHKPVDDMTGLSQAIRVLMGCPFRNGLRARR
Prediction	755365641330110100033133010003354333221110145231100002434445514131301423425244202000102020441567424411441146324531141243333433352321001102033020212323330426304514221015204400520364125103300530445165430200000110000103267332301020343064374025102300210337446658
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCCCHHHHHHHHHHHCCCEEEEHCCCCCCCCCCEEHCCCCCEEEEHCCCCCCCCCCCCCEEEEEHCCCCCCCCCCEEEEEEEEEEHCCHHHHHHHHHHHHHHCCCCCCHCCCCCCCCCCCCCCCCEEEEEEEEEEEEEHCCCCEEEHCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHCCCCEEEEEHCCCCEEEEHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
MPPLTSLAPTTAERIRSACARAGGALLVVEREDPVPVPIHHLLYDGSFAVAVPVDRGEVSGSQALLELTDYAPLPVREPVRSLVWIRGCLHQIPPAELVETLDLIATDNPNPALLQVETPRPGPADAAETRYTMQRLEIESVVVTDATGAEPVTVADLLAARPDPFCEIESTLLWHLATAHDDVVARLVSRLPAPLRRGQIRPLGLDRYGVRFRIEARDGDRDIRLPFHKPVDDMTGLSQAIRVLMGCPFRNGLRARR

5bncA

0.17

0.16

0.93

2.28

MUSTER

LTPVAVVRPSAAEEARTIAASTNVGTLATLTTEGDASFVTYGLLGGAPVLCVSDMAEHGRNLAHDASIAIVAPSAESDPASARVTLAGVAERPEGDELAAARAAHLDAVAA-----------AKYYIDYSDFSVWVLRVQRVRWVGGYRMDSTTGEAYAAAEADPVTPRAAGAIAHLNADHADSLLAMARNLGGYPDTGEAVCTGADRYGLDLRVTTERGVAYTRVGYAAPISSFDQLRAATVELAQRAKQS------

5bncA

0.17

0.16

0.93

3.25

dPPAS

TPVADVVRPSAAEEARTIAASTNVGTLATLTTEGDASFVTYGLLGGAPVLCVSDMAEHGRNLAHDPRASIAIVAPSAESDSARVTLAGVAERPEGDELAAARAAHLDAVAAAK-----------YYIDYSDFSVWVLRVQRVRWVGGYRMDSTTGEAYAAAEADPVTPRAAGAIAHLNADHADSLLAMARNLGGYPDTGEAVCTGADRYGLDLRVTTERGVAYTRVGYAAPISSFDQLRAATVELAQRAKQS------

5bncA

0.18

0.17

0.93

4.61

wdPPAS

VPPADVVRPSAAEEARTIAASTNVGTLATLTTEGDASFVTYGLLGGAPVLCVSDMAEHGRNLAHDPRASIAIVAPSAESASARVTLAGVAERPEGDELAAARAAHLDAVAAAKY-----------YIDYSDFSVWVLRVQRVRWVGGYGMDSTTGEAYAAAEADPVTPRAAGAIAHLNADHADSLLAMARNLGGYPDTGEAVCTGADRYGLDLRVTTERGVAYTRVGYAAPISSFDQLRAATVELAQRAKQS------

5bncA

0.17

0.16

0.93

2.90

wMUSTER

LTPVAVVRPSAAEEARTIAASTNVGTLATLTTEGDASFVTYGLLGGAPVLCVSDMAEHGRNLAHDPRASIAIVAPSAELASARVTLAGVAERPEGDELAAARAAHLDAVAA-----------AKYYIDYSDFSVWVLRVQRVRWVGGYRMDSTTGEAYAAAEADPVTPRAAGAIAHLNADHADSLLAMARNLGGYPDTGEAVCTGADRYGLDLRVTTERGVAYTRVGYAAPISSFDQLRAATVELAQRAKQS------

5bncA

0.18

0.17

0.93

4.52

wPPAS

VPPADVVRPSAAEEARTIAASTNVGTLATLTTEGDASFVTYGLLGGAPVLCVSDMAEHGRNLAHDPRASIAIVAPSAESASARVTLAGVAERPEGDELAAARAAHLDAVAAAKY-----------YIDYSDFSVWVLRVQRVRWVGGYGMDSTTGEAYAAAEADPVTPRAAGAIAHLNADHADSLLAMARNLGGYPDTGEAVCTGADRYGLDLRVTTERGVAYTRVGYAAPISSFDQLRAATVELAQRAKQS------

5bncA

0.17

0.16

0.93

7.31

dPPAS2

TPVADVVRPSAAEEARTIAASTNVGTLATLTTEGDASFVTYGLLGGAPVLCVSDMAEHGRNLAHDPRASIAIVAPSAESDSARVTLAGVAERPEGDELAAARAAHLDAVAAAK-----------YYIDYSDFSVWVLRVQRVRWVGGYRMDSTTGEAYAAAEADPVTPRAAGAIAHLNADHADSLLAMARNLGGYPDTGEAVCTGADRYGLDLRVTTERGVAYTRVGYAAPISSFDQLRAATVELAQRAKQS------

5bncA

0.17

0.16

0.93

3.71

PPAS

LTPADVVRPSAAEEARTIAASTNVGTLATLTTEGDASFVTYGLLGGAPVLCVSDMAEHGRNLAHDPRASIAIVAPSAESASARVTLAGVAERPEGDELAAARAAHLDAVAAAKY-----------YIDYSDFSVWVLRVQRVRWVGGYRMDSTTGEAYAAAEADPVTPRAAGAIAHLNADHADSLLAMARNLGGYPDTGEAVCTGADRYGLDLRVTTERGVAYTRVGYAAPISSFDQLRAATVELAQRAKQS------

5bncA

0.17

0.16

0.93

4.28

Env-PPAS

LTPVAVVRPSAAEEARTIAASTNVGTLATLTTEGDASFVTYGLLGGAPVLCVSDMAEHGRNLAHDPRASIAIVAPSAESASARVTLAGVAERPEGDELAAARAAHLDAVAAAKY-----------YIDYSDFSVWVLRVQRVRWVGGYRMDSTTGEAYAAAEADPVTPRAAGAIAHLNADHADSLLAMARNLGGYPDTGEAVCTGADRYGLDLRVTTERGVAYTRVGYAAPISSFDQLRAATVELAQRAKQS------

4n7rC

0.15

0.14

0.90

2.17

MUSTER

----STHKPFPAEVSRSIMELSSVGTLSTLTHDGWPLGVFAVDKDGTPVLCL------NRSVSPDKRSALHVQLEQCGLRTPQCTIQGSIGRPGDDTVLKRLSATWREKF---------------GEEVKEDSLYVVAVDRVLQMEDFMGIWVASSDYKNASPDPLRDIAEDIVNQINANNMEDIFRFCNVYDLDFVVSETKMIWMDRLGFDLRVWSPRGVYDVRIPFPMEVTDEKGAKSSFNGMSQLAWEVSYCPAD

4n7rC

0.15

0.14

0.90

2.99

dPPAS

----STHKPFPAEVSRSIMELSSVGTLSTLTHDGWPLGVFAVDKDGTPVLCLN------RSVSPDKRSALHVQLEQCGLRTPQCTIQGSIGRPGDDTVLKRLSATWREKF---------------GEEVKEDSLYVVAVDRVLQMEDFMGIWVASSDYKNASPDPLRDIAEDIVNQINANNMEDIFRFCNVYDLDFVVSETKMIWMDRLGFDLRVWSPRGVYDVRIPFPMEVTDEKGAKSSFNGMSQLAWEVEKSYCP

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=0.80

Estimated TM-score = 0.82±0.08

Estimated RMSD = 4.2±2.8Å

Download Model 2

C-score=-1.67

Download Model 3

C-score=-0.72

Download Model 4

C-score=-0.68

Download Model 5

C-score=0.59

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	5bncA	0.907	1.09	0.170	0.934
2	4n7rC	0.759	2.81	0.159	0.899
3	2arzA	0.540	3.63	0.083	0.663
4	3dnhA	0.521	3.46	0.104	0.628
5	1xhnA	0.501	2.27	0.124	0.550
6	3swjA	0.482	3.32	0.048	0.578
7	3gasA	0.481	3.17	0.086	0.578
8	2iabA	0.463	2.83	0.125	0.531
9	1nrgA	0.444	3.81	0.057	0.550
10	2a2jA	0.444	3.46	0.096	0.535

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.14	10	4qvbA	F42	Rep, Mult	31,36,39,40,51,52,56,57,58,61,132
2	0.06	4	4ybnB	FAD	Rep, Mult	73,81,83,84,85,87,143,145
3	0.06	4	3gasB	HEM	Rep, Mult	52,53,55,56,58,125,126,129,132
4	0.03	2	3swjA	HEM	Rep, Mult	173,176,181,184,246
5	0.03	2	2iab0	III	Rep, Mult	24,26,28,29,30,31,32,34,35,36,38,65,67,69,70,71,83,85,145
6	0.03	2	2ig6B	FMN	Rep, Mult	206,211,213
7	0.01	1	2gpjA	CA	Rep, Mult	176,180,181
8	0.01	1	2zhcA	MG	Rep, Mult	207,210
9	0.01	1	3rbxA	CA	Rep, Mult	46,97
10	0.01	1	3sahB	MG	Rep, Mult	30,164
11	0.01	1	2ou5A	FMN	Rep, Mult	71,85,87,143,145
12	0.01	1	1l0zA	BR	Rep, Mult	11,12,153
13	0.01	1	1dxeA	MG	Rep, Mult	138,157
14	0.01	1	2h1iC	CA	Rep, Mult	164,167
15	0.01	1	3lu2B	ZN	Rep, Mult	181,183
16	0.01	1	3dp2D	4BE	Rep, Mult	228,230
17	0.01	1	5bncB	MG	Rep, Mult	54,130,133
18	0.01	1	1p6bA	ZN	Rep, Mult	176,207

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	1jnwA	0.428	3.60	0.078	0.523	1.4.3.5	NA
2	0.060	1f7uA	0.395	5.87	0.040	0.651	6.1.1.19	176
3	0.060	1ci0A	0.436	3.69	0.047	0.535	1.4.3.5	NA
4	0.060	1qhoA	0.389	5.84	0.064	0.643	3.2.1.133	16
5	0.060	1ffyA	0.381	6.24	0.025	0.643	6.1.1.5	181
6	0.060	2vgkD	0.389	6.30	0.033	0.670	3.4.16.4	NA
7	0.060	1tz7A	0.402	5.84	0.054	0.659	2.4.1.25	NA
8	0.060	2aaaA	0.379	5.76	0.050	0.624	3.2.1.1	NA
9	0.060	1jxaA	0.403	5.94	0.087	0.678	2.6.1.16	NA
10	0.060	1a47A	0.380	6.02	0.042	0.636	2.4.1.19	16
11	0.060	3gm8A	0.380	6.64	0.033	0.705	3.2.1.-	13
12	0.060	1x1nA	0.404	5.61	0.056	0.643	2.4.1.25	NA
13	0.060	2vf4X	0.285	6.81	0.095	0.543	2.6.1.16	67
14	0.060	1cygA	0.382	5.80	0.078	0.639	2.4.1.19	69
15	0.060	1e1cA	0.383	6.02	0.047	0.636	5.4.99.2	181
16	0.060	1ug9A	0.394	6.19	0.053	0.694	3.2.1.70	NA
17	0.060	3c8zB	0.385	5.68	0.092	0.632	6.1.1.16	NA
18	0.060	1cgtA	0.385	5.93	0.039	0.643	2.4.1.19	NA
19	0.060	2taaA	0.382	5.77	0.056	0.632	3.2.1.1	198

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.40	0.759	2.81	0.16	0.90	4n7rC	GO:0006783 GO:0009507 GO:0009534 GO:0009536 GO:0009570 GO:0009767 GO:0009791 GO:0010181 GO:0015995 GO:0016491 GO:0033014 GO:0043234 GO:0043495 GO:0055114 GO:0070455
1	0.40	0.907	1.09	0.17	0.93	5bncA	GO:0010181 GO:0016491 GO:0055114
2	0.13	0.525	3.45	0.10	0.63	3dnhA	GO:0010181 GO:0016491 GO:0055114
3	0.10	0.515	2.14	0.13	0.56	1xhnA	GO:0003714 GO:0005576 GO:0005615 GO:0005667 GO:0006355 GO:0006357 GO:0007275 GO:0008134 GO:0008283 GO:0010181 GO:0016491 GO:0040008 GO:0055114 GO:0070062 GO:1903507
4	0.10	0.441	2.91	0.06	0.52	3tgvA	GO:0004733 GO:0010181 GO:0016491 GO:0042823 GO:0055114
5	0.09	0.540	3.63	0.08	0.66	2arzA	GO:0010181 GO:0016491 GO:0055114
6	0.09	0.428	2.99	0.10	0.50	4qvbB	GO:0004733 GO:0010181 GO:0016491 GO:0030170 GO:0042803 GO:0042816 GO:0042823 GO:0055114
7	0.06	0.451	2.89	0.07	0.52	1rfeA	GO:0004733 GO:0010181 GO:0016491 GO:0042823 GO:0055114
8	0.06	0.431	2.35	0.06	0.48	1vl7A	GO:0004733 GO:0010181 GO:0016491 GO:0042823 GO:0055114
9	0.06	0.265	6.33	0.04	0.48	4r1iA	GO:0015558 GO:0016020 GO:0016021 GO:1902604
10	0.06	0.249	5.93	0.04	0.41	3szmC	GO:0005654 GO:0005737 GO:0005815 GO:0005856 GO:0021987 GO:0042802 GO:0071850
11	0.06	0.256	6.26	0.05	0.45	3gn6C	GO:0046872
12	0.06	0.299	6.19	0.07	0.52	3aq0C	GO:0004659 GO:0005739 GO:0006744 GO:0008299 GO:0009507 GO:0009536 GO:0009793 GO:0016740 GO:0046872 GO:0050347 GO:0052924
13	0.06	0.267	6.33	0.04	0.47	1gpzA	GO:0002376 GO:0004252 GO:0005509 GO:0005576 GO:0006508 GO:0006955 GO:0006956 GO:0006958 GO:0008233 GO:0008236 GO:0016787 GO:0045087 GO:0070062 GO:0072562
14	0.06	0.212	5.94	0.03	0.36	3tu4K	GO:0000781 GO:0000784 GO:0001308 GO:0003677 GO:0003682 GO:0003690 GO:0003697 GO:0005634 GO:0005677 GO:0005720 GO:0005724 GO:0005730 GO:0006351 GO:0006355 GO:0030466 GO:0031491 GO:0031493 GO:0031507 GO:0042802 GO:0070481
15	0.06	0.233	5.15	0.09	0.36	1lj9A	GO:0003677 GO:0003700 GO:0006351 GO:0006355
16	0.06	0.235	5.78	0.06	0.38	2fvuB	GO:0000781 GO:0000784 GO:0001308 GO:0003677 GO:0003682 GO:0003690 GO:0003697 GO:0005634 GO:0005677 GO:0005720 GO:0005724 GO:0005730 GO:0006351 GO:0006355 GO:0030466 GO:0031491 GO:0031493 GO:0031507 GO:0042802 GO:0070481
17	0.06	0.212	4.84	0.07	0.30	3my2A	GO:0005886 GO:0005887 GO:0015221 GO:0015920 GO:0016020 GO:0016021 GO:0017089 GO:0030288 GO:0042802 GO:0043165 GO:0046836
18	0.06	0.157	4.29	0.03	0.21	4r2zA	GO:0005886 GO:0006810 GO:0015879 GO:0016020 GO:0030165 GO:0031526 GO:0034767 GO:0044070 GO:0070062 GO:0090002 GO:0090314

Consensus prediction of GO terms

Molecular Function	GO:0010181	GO:0016491	GO:0043495
GO-Score	0.75	0.75	0.40
Biological Processes	GO:0009791	GO:0009767	GO:0070455	GO:0015995
GO-Score	0.40	0.40	0.40	0.40
Cellular Component	GO:0009570	GO:0043234	GO:0009534
GO-Score	0.40	0.40	0.40

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.