I-TASSER results

Input Sequence in FASTA format

>protein (191 residues)
MAMNLLHRRHCSSAGWEKAVANQLLPWALQHVELGPRTLEIGPGYGATLQALLGLTASLT
AVEVDNSMVERLNRRYGQRARIIRGDGTQTGLPDDHFTSVVCFTMLHHVASAQLQDQLFA
EAYRVLQPGGVFAGSDGVPSLPFRLIHIADTYTPIAPADLPGRLRAVGFTDIHVDVAGAR
LRWRATKPVAA

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 \| \| \| \| \| \| \| \| \| MAMNLLHRRHCSSAGWEKAVANQLLPWALQHVELGPRTLEIGPGYGATLQALLGLTASLTAVEVDNSMVERLNRRYGQRARIIRGDGTQTGLPDDHFTSVVCFTMLHHVASAQLQDQLFAEAYRVLQPGGVFAGSDGVPSLPFRLIHIADTYTPIAPADLPGRLRAVGFTDIHVDVAGARLRWRATKPVAA
Prediction	CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEHCCCCCHHHHHHHHHCCEEEEHCCCHHHHHHHHHHCCCCCEEEHCCHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEHCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEEEEHCCEEEEEEEHCCCC
Conf.Score	98558889875775899999999999999879999858998789988999999889979998599999999999769995999968666999988633566777888678857789999999998589949999977999875444346766679999999999998995799997588899999857899
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 \| \| \| \| \| \| \| \| \| MAMNLLHRRHCSSAGWEKAVANQLLPWALQHVELGPRTLEIGPGYGATLQALLGLTASLTAVEVDNSMVERLNRRYGQRARIIRGDGTQTGLPDDHFTSVVCFTMLHHVASAQLQDQLFAEAYRVLQPGGVFAGSDGVPSLPFRLIHIADTYTPIAPADLPGRLRAVGFTDIHVDVAGARLRWRATKPVAA
Prediction	65144024212554301420053014202650653540430142013003301631040100221350043027525740311201035041446120000000000102337325300310220533411000001134342322433421341337303510570425404243443321010212468
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180

                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEHCCCCCHHHHHHHHHCCEEEEHCCCHHHHHHHHHHCCCCCEEEHCCHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEHCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEEEEHCCEEEEEEEHCCCC
MAMNLLHRRHCSSAGWEKAVANQLLPWALQHVELGPRTLEIGPGYGATLQALLGLTASLTAVEVDNSMVERLNRRYGQRARIIRGDGTQTGLPDDHFTSVVCFTMLHHVASAQLQDQLFAEAYRVLQPGGVFAGSDGVPSLPFRLIHIADTYTPIAPADLPGRLRAVGFTDIHVDVAGARLRWRATKPVAA

3ou2A

0.19

0.18

0.97

2.19

MUSTER

LSYRARASEYDATVPYMDSAAPAALERLRAG-NIRGDVLELASGTGYWTRHLSGLADRVTALDGSAEMIAEAGRHGLDNVEFRQQDLFDWTP-DRQWDAVFFAHWLAHVPD-DRFEAFWESVRSAVAPGGVVEFVDVTDHEVAVRRTLQDGKVFRSPAELTERLTALGWSCSVDEVHPGFLYATCRPPR--

3ou2A

0.18

0.98

3.01

dPPAS

SYYRARASEYDATFVPYMDSAAPAALERLRAGNIRGDVLELASGTGYWTRHLSGLADRVTALDGSAEMIAEAGRHGLDNVEFRQQDLFDWTP-DRQWDAVFFAHWLAHVPD-DRFEAFWESVRSAVAPGGVVEFVDVTDHEVAVRRTLQDGKVFRSPAELTERLTALGWSCSVDEVHPGFLYATCRPGPR-

3ou2A

0.19

0.18

0.98

2.62

wdPPAS

SYYRARASEYDATFVPYMDSAAPAALERLRAGNIRGDVLELASGTGYWTRHLSGLADRVTALDGSAEMIAEAGRHGLDNVEFRQQDLFDWTP-DRQWDAVFFAHWLAHVPD-DRFEAFWESVRSAVAPGGVVEFVDVTDHEVAVRRTLQDGKVFRSPAELTERLTALGWSCSVDEVHPGFLYATCRPPR--

3ou2A

0.19

0.18

0.97

2.50

wMUSTER

LSYRARASEYDATVPYMDSAAPAALERLRA-GNIRGDVLELASGTGYWTRHLSGLADRVTALDGSAEMIAEAGRHGLDNVEFRQQDLFDWTP-DRQWDAVFFAHWLAHVPD-DRFEAFWESVRSAVAPGGVVEFVDVTDHEVAVRRTLQDGKVFRSPAELTERLTALGWSCSVDEVHPGFLYATCRPPR--

3ou2A

0.19

0.18

0.98

2.59

wPPAS

LSYRARASEYDATFVPYMDSAAPAALERLRAGNIRGDVLELASGTGYWTRHLSGLADRVTALDGSAEMIAEAGRHGLDNVEFRQQDLFDWTP-DRQWDAVFFAHWLAHVPD-DRFEAFWESVRSAVAPGGVVEFVDVTDHEVAVRRTLQDGKVFRSPAELTERLTALGWSCSVDEVHPGFLYATCRPPR--

3ou2A

0.19

0.18

0.98

3.25

dPPAS2

SYYRARASEYDATFVPYMDSAAPAALERLRAGNIRGDVLELASGTGYWTRHLSGLADRVTALDGSAEMIAEAGRHGLDNVEFRQQDLFDWTP-DRQWDAVFFAHWLAHVPD-DRFEAFWESVRSAVAPGGVVEFVDVTDHEVAVRRTLQDGKVFRSPAELTERLTALGWSCSVDEVHPGFLYATCRPPR--

3ou2A

0.19

0.18

0.98

2.40

PPAS

LSYRARASEYDATFVPYMDSAAPAALERLRAGNIRGDVLELASGTGYWTRHLSGLADRVTALDGSAEMIAEAGRHGLDNVEFRQQDLFDWTP-DRQWDAVFFAHWLAHVPD-DRFEAFWESVRSAVAPGGVVEFVDVTDHEVAVRRTLQDGKVFRSPAELTERLTALGWSCSVDEVHPGFLYATCRPPR--

3ou2A

0.19

0.18

0.98

2.56

Env-PPAS

LSYRARASEYDATFVPYMDSAAPAALERLRAGNIRGDVLELASGTGYWTRHLSGLADRVTALDGSAEMIAEAGRHGLDNVEFRQQDLFDWTP-DRQWDAVFFAHWLAHVPD-DRFEAFWESVRSAVAPGGVVEFVDVTDHEVAVRRTLQDGKVFRSPAELTERLTALGWSCSVDEVHPGFLYATCRPPR--

3dh0B

0.16

0.15

0.94

2.19

MUSTER

FDPSKIKKLDDPSRLELFD-PEKVLKEFG--LKEGMTVLDVGTGAGFYLPYLSKMVGKVYAIDVQEEMVNYAWEKVNKNVEVLKSEENKIPLPDNTVDFIFMAFTFHELSE---PLKFLEELKRVAKPFAYLAIIDWKKEERD---KGPPPEEVYSEWEVGLILEDAGIRVGRVVEVGKYCFGVYAMIV--

3hnrA

0.16

0.15

0.93

2.77

dPPAS

------------DIQYKEVFAHYEDILEDVVNKSFGNVLEFGVGTGNLTNKLLLAGRTVYGIEPSREMRMIAKEKLPKEFSITEGDFLSFEV-PTSIDTIVSTYAFHHLTD-DEKNVAIAKYSQLLNKGGKIVFADTIFADFHQLANDLQTEYYTRIPVMQTIFENNGFHVTFTRLNHFVWVMEATKQLEH

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 3 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=0.60

Estimated TM-score = 0.79±0.09

Estimated RMSD = 4.0±2.7Å

Download Model 2

C-score=-2.52

Download Model 3

C-score=-2.40

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	3ou2A	0.885	1.93	0.176	0.974
2	4iv0A	0.834	2.40	0.151	0.969
3	1wznA	0.834	2.46	0.135	0.963
4	2iipA	0.831	2.41	0.140	0.974
5	5thyA	0.827	2.67	0.140	0.974
6	3uj6A	0.825	2.32	0.176	0.953
7	4pneA	0.824	2.27	0.215	0.942
8	2avnA	0.822	2.08	0.158	0.927
9	2ex4A	0.822	2.34	0.121	0.953
10	2a14A	0.821	2.57	0.123	0.979

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.55	100	3ou7A	SAM	Rep, Mult	3,10,14,42,43,44,63,64,65,68,85,86,87,88,103,104,105,108
2	0.03	7	4er6A	AW2	Rep, Mult	28,40,42,43,44,48,63,64,65,85,86,87,101,104,109,133,134,182
3	0.00	1	1ri1A	GTG	Rep, Mult	21,22,25,50,51,75,180
4	0.00	1	3ou7D	2HE	Rep, Mult	3,6,13,14,108,152
5	0.00	1	3dtnA	CA	Rep, Mult	66,84
6	0.00	1	3ujdA	PC	Rep, Mult	6,104,137,146,150,152
7	0.00	1	3i9fA	ZN	Rep, Mult	71,74

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.414	3hnrA	0.765	2.82	0.166	0.900	2.1.1.-	107
2	0.241	2iftA	0.621	2.96	0.144	0.764	2.1.1.52	53,57
3	0.213	3lccA	0.772	2.73	0.135	0.927	2.1.1.-	42
4	0.142	3e05D	0.696	2.57	0.102	0.822	2.1.1.132	NA
5	0.120	2pxxA	0.779	2.52	0.180	0.900	3.4.24.71	46
6	0.119	2a14A	0.821	2.57	0.123	0.979	2.1.1.49	42,44
7	0.107	3grzB	0.699	2.52	0.124	0.811	2.1.1.-	48
8	0.100	3e05B	0.693	2.45	0.104	0.811	2.1.1.132	NA
9	0.095	1xxlA	0.761	2.02	0.206	0.859	2.1.1.-	107
10	0.094	1f38A	0.684	2.51	0.124	0.811	2.1.1.-	NA
11	0.092	3bwmA	0.699	3.14	0.133	0.859	2.1.1.6	NA
12	0.085	2cl5A	0.685	3.16	0.131	0.869	2.1.1.6	NA
13	0.082	3gdhA	0.689	2.78	0.080	0.822	2.1.1.-	NA
14	0.078	1pjzA	0.659	3.18	0.110	0.838	2.1.1.67	37,92
15	0.067	1nt2A	0.675	3.03	0.113	0.817	2.1.1.-	NA
16	0.060	2aovA	0.772	2.94	0.115	0.948	2.1.1.8	105
17	0.060	1wznA	0.834	2.46	0.135	0.963	2.1.1.-	NA
18	0.060	1kpgA	0.784	2.51	0.140	0.932	2.1.1.79	NA
19	0.060	1ri5A	0.759	2.74	0.132	0.911	2.1.1.56	NA
20	0.060	1ri1A	0.758	2.74	0.132	0.911	2.1.1.56	42
21	0.060	1kpiA	0.797	2.71	0.109	0.958	2.1.1.79	68
22	0.060	3c6kD	0.727	3.27	0.113	0.916	2.5.1.22	83,109
23	0.060	2o06A	0.740	3.35	0.117	0.937	2.5.1.16	42,44,85,118
24	0.060	1im8A	0.771	3.01	0.134	0.937	2.1.1.-	NA
25	0.060	3i58A	0.775	2.69	0.145	0.937	2.1.1.-	107
26	0.060	1tw2B	0.777	2.82	0.137	0.948	2.1.1.-	NA
27	0.060	1kyzE	0.773	2.84	0.106	0.942	2.1.1.68	47
28	0.060	1mjfA	0.726	3.16	0.153	0.916	2.5.1.16	42,63
29	0.060	3eppB	0.750	2.68	0.161	0.906	2.1.1.56	NA
30	0.060	3bwbA	0.734	3.18	0.181	0.921	2.5.1.16	5,41,44,104
31	0.060	3c6mD	0.735	3.18	0.126	0.911	2.5.1.22	28,183
32	0.060	2h11B	0.766	2.72	0.079	0.927	2.1.1.67	47
33	0.060	3bgdA	0.759	2.75	0.096	0.927	2.1.1.67	47
34	0.060	1kywC	0.769	2.90	0.117	0.942	2.1.1.68	107

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.43	0.814	2.20	0.20	0.92	1vlmA	GO:0005737 GO:0008152 GO:0008168 GO:0008757 GO:0032259
1	0.37	0.765	2.82	0.17	0.90	3hnrA	GO:0008152 GO:0008168 GO:0008757 GO:0016740 GO:0032259
2	0.34	0.834	2.46	0.14	0.96	1wznA
3	0.33	0.796	2.41	0.22	0.93	2gs9A	GO:0008152 GO:0008168 GO:0032259
4	0.33	0.790	2.48	0.21	0.92	3busA	GO:0008152 GO:0008168 GO:0016740 GO:0032259
5	0.33	0.780	2.94	0.13	0.95	3h2bB	GO:0008168 GO:0016740 GO:0032259
6	0.32	0.793	2.92	0.12	0.95	4necB	GO:0008168 GO:0016740 GO:0032259
7	0.32	0.818	2.34	0.15	0.96	4oqdC	GO:0008168 GO:0008757 GO:0016740 GO:0017000 GO:0032259 GO:0042803
8	0.31	0.771	2.48	0.16	0.91	4qtuB	GO:0000056 GO:0000447 GO:0005634 GO:0005730 GO:0005737 GO:0006364 GO:0008152 GO:0008168 GO:0008757 GO:0016435 GO:0016740 GO:0032259 GO:0070476
9	0.31	0.798	2.66	0.17	0.96	4qvgC	GO:0008168 GO:0008171 GO:0032259
10	0.30	0.818	2.44	0.16	0.96	4krhA	GO:0008152 GO:0008168 GO:0032259 GO:0046872 GO:0051536 GO:0051539
11	0.30	0.671	2.82	0.17	0.81	3fycA	GO:0000154 GO:0000179 GO:0003723 GO:0005737 GO:0006364 GO:0008168 GO:0008649 GO:0016433 GO:0016740 GO:0031167 GO:0032259
12	0.30	0.870	2.07	0.18	0.96	3ou7A	GO:0008168 GO:0016740 GO:0032259 GO:0046872 GO:0051536 GO:0051539
13	0.30	0.732	2.67	0.11	0.86	5cm2Z	GO:0000049 GO:0002098 GO:0005634 GO:0005737 GO:0005829 GO:0008152 GO:0008168 GO:0008198 GO:0016300 GO:0016706 GO:0030488 GO:0032259 GO:0055114
14	0.29	0.792	2.80	0.14	0.95	2o57A
15	0.29	0.756	2.96	0.19	0.91	3g2pA	GO:0046872 GO:0051536 GO:0051539
16	0.29	0.793	2.40	0.18	0.93	3e23A	GO:0008152 GO:0008168 GO:0032259 GO:0046872 GO:0051536 GO:0051539
17	0.28	0.763	2.00	0.21	0.86	2gluA	GO:0005737 GO:0008152 GO:0008168 GO:0008757 GO:0016740 GO:0032259
18	0.28	0.832	2.08	0.16	0.94	2avnA	GO:0008152 GO:0008168 GO:0016740 GO:0032259
19	0.27	0.802	2.30	0.15	0.92	3dh0B	GO:0005737 GO:0008757 GO:0032259 GO:0046872 GO:0051536 GO:0051539
20	0.27	0.843	2.66	0.12	0.99	4krgA	GO:0008152 GO:0008168 GO:0032259
21	0.27	0.792	2.71	0.18	0.95	1x19A	GO:0008168 GO:0008171 GO:0016740 GO:0032259 GO:0046872 GO:0051536 GO:0051539
22	0.26	0.799	2.90	0.14	0.96	1im8A	GO:0002098 GO:0005737 GO:0008757 GO:0016300 GO:0016740 GO:0016743 GO:0030488 GO:0032259 GO:1904047
23	0.26	0.822	2.27	0.21	0.94	4pneB	GO:0008152 GO:0008168 GO:0016740 GO:0032259
24	0.26	0.813	2.52	0.13	0.96	5je1A	GO:0008168 GO:0016740 GO:0032259
25	0.25	0.775	2.93	0.16	0.92	3dtnA	GO:0046872
26	0.25	0.818	2.27	0.13	0.95	1xtpA	GO:0005737 GO:0006480 GO:0008168
27	0.25	0.688	2.74	0.15	0.83	2p35A	GO:0005737 GO:0008168 GO:0016740 GO:0030798 GO:0032259
28	0.24	0.809	2.61	0.15	0.96	1ve3B	GO:0046872 GO:0051536 GO:0051539
29	0.24	0.764	2.01	0.21	0.85	1vl5A	GO:0008152 GO:0008168 GO:0016740 GO:0032259
30	0.24	0.769	2.88	0.16	0.93	3dlcA	GO:0008152 GO:0008168 GO:0016740 GO:0032259 GO:0046872 GO:0051536 GO:0051539
31	0.24	0.711	3.35	0.19	0.90	4rsrA	GO:0008168 GO:0016740 GO:0032259 GO:0046872 GO:0051536 GO:0051539
32	0.24	0.749	3.28	0.18	0.92	2yqzA	GO:0008152 GO:0008168 GO:0032259 GO:0046872 GO:0051536 GO:0051539
33	0.23	0.680	3.15	0.14	0.84	3cggA	GO:0008168 GO:0016740 GO:0032259
34	0.23	0.721	2.77	0.18	0.85	3ccfB	GO:0008152 GO:0008168 GO:0016740 GO:0030798 GO:0032259
35	0.22	0.721	2.47	0.15	0.84	3egeA	GO:0008152 GO:0008168 GO:0032259
36	0.22	0.655	3.21	0.13	0.84	2kw5A	GO:0005737 GO:0008757 GO:0032259
37	0.22	0.772	2.73	0.14	0.93	3lccA	GO:0005886 GO:0006952 GO:0008168 GO:0008757 GO:0016740 GO:0018708 GO:0019762 GO:0032259
38	0.21	0.674	3.01	0.13	0.84	2xvaA	GO:0005737 GO:0005829 GO:0008168 GO:0008757 GO:0009636 GO:0016740 GO:0032259 GO:0046677 GO:0046690
39	0.21	0.614	3.23	0.17	0.77	3douA	GO:0001510 GO:0005737 GO:0006364 GO:0008168 GO:0008650 GO:0016740 GO:0031167 GO:0032259
40	0.21	0.795	2.43	0.14	0.93	4qdkA	GO:0005737 GO:0008168 GO:0008757 GO:0015979 GO:0015995 GO:0016740 GO:0032259 GO:0036068 GO:0046406
41	0.20	0.684	2.51	0.12	0.81	1f38A	GO:0006479 GO:0008168 GO:0008276 GO:0009236 GO:0016740 GO:0032259 GO:0046140
42	0.20	0.778	2.95	0.17	0.94	3kkzA	GO:0046872 GO:0051536 GO:0051539
43	0.19	0.778	2.96	0.17	0.94	3e7pA	GO:0046872 GO:0051536 GO:0051539
44	0.19	0.655	3.03	0.14	0.82	2i6gB	GO:0005737 GO:0008168 GO:0008757 GO:0016740 GO:0032259 GO:0046690
45	0.18	0.766	3.02	0.14	0.93	3f4kA	GO:0005737 GO:0008168 GO:0008757 GO:0016740 GO:0032259 GO:0046872 GO:0051536 GO:0051539
46	0.17	0.835	2.31	0.17	0.96	3uj7A	GO:0008168 GO:0016740 GO:0032259 GO:0046872 GO:0051536 GO:0051539
47	0.17	0.821	2.27	0.12	0.95	5cvdA	GO:0005634 GO:0005654 GO:0005737 GO:0006480 GO:0007051 GO:0007059 GO:0008168 GO:0008276 GO:0016740 GO:0018011 GO:0018012 GO:0018016 GO:0032259 GO:0035572 GO:0035573 GO:0071885
48	0.15	0.601	3.14	0.12	0.77	1yubA	GO:0000154 GO:0000179 GO:0003723 GO:0008168 GO:0008649 GO:0016740 GO:0031167 GO:0032259 GO:0046677 GO:0052910
49	0.13	0.657	3.20	0.17	0.83	4hg2B	GO:0008152 GO:0008168 GO:0016740 GO:0032259
50	0.12	0.809	2.52	0.14	0.95	1y8cA	GO:0008168 GO:0016740 GO:0032259
51	0.11	0.682	2.54	0.12	0.80	3i9fB	GO:0008152 GO:0008168 GO:0032259 GO:0046872
52	0.10	0.803	2.49	0.14	0.95	1kpgA	GO:0005737 GO:0005886 GO:0006629 GO:0008168 GO:0008610 GO:0008825 GO:0016740 GO:0032259 GO:0046500 GO:0071768
53	0.09	0.570	3.63	0.14	0.75	4dzrA	GO:0003676 GO:0006479 GO:0008168 GO:0008276 GO:0016740 GO:0018364 GO:0032259 GO:0036009 GO:0046872
54	0.07	0.720	2.83	0.14	0.86	1p91A	GO:0005737 GO:0006364 GO:0008168 GO:0008270 GO:0008989 GO:0016740 GO:0032259 GO:0046872 GO:0052911 GO:0070475
55	0.07	0.761	2.80	0.13	0.94	4rv9A	GO:0008168 GO:0016740 GO:0032259 GO:0046872 GO:0051536 GO:0051539
56	0.07	0.698	3.35	0.12	0.88	3hp7A	GO:0003723 GO:0008168 GO:0032259
57	0.07	0.570	3.13	0.16	0.69	4l7vA	GO:0004719 GO:0005737 GO:0006464 GO:0006479 GO:0008168 GO:0016740 GO:0030091 GO:0032259

Consensus prediction of GO terms

Molecular Function	GO:0008757
GO-Score	0.64
Biological Processes	GO:0032259
GO-Score	0.84
Cellular Component	GO:0005737
GO-Score	0.43

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv3832c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]