Threading Zmax Znorm MUSTER 4.10 0.71 dPPAS 8.16 0.88 wdPPAS 7.62 0.82 wMUSTER 4.41 0.76 wPPAS 5.26 0.75 dPPAS2 10.50 1.00 PPAS 6.15 0.88 Env-PPAS 6.44 0.81 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=20200) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.21 0.45+-0.15 8.9+-4.6 13822 0.134 model2 -1.98 12829 0.167 model3 -4.50 1257 0.013 model4 -3.04 6024 0.058 model5 -5.00 602 0.006 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).