Threading Zmax Znorm MUSTER 4.01 0.69 dPPAS 6.08 0.65 wdPPAS 5.15 0.55 wMUSTER 3.85 0.66 wPPAS 4.88 0.70 dPPAS2 12.17 1.16 PPAS 5.11 0.73 Env-PPAS 6.20 0.78 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=18549) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -3.32 0.35+-0.12 12.7+-4.3 4866 0.049 model2 -3.76 3164 0.032 model3 -3.80 2756 0.030 model4 -4.43 1291 0.016 model5 -4.25 1810 0.019 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).