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I-TASSER results for job id Rv3748

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

 Input Sequence in FASTA format
 Predicted Secondary Structure
 Predicted Solvent Accessibility
 Predicted Normalized B-facotr
 Top 10 threading templates used by I-TASSER
 Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)
 Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)
 Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)
  Ligand binding sites

Rank C-score Cluster
size		 PDB
Hit		 Lig
Name		 Download
Complex		 Ligand Binding Site Residues
10.06 3 2qkiA III Rep, Mult 2,40,41,42,43,71,74,89,90
20.06 3 4qh1A BXA Rep, Mult 18,20,43,80,85
30.04 2 4kdvA CA Rep, Mult 31,118
40.04 2 1xf1A CA Rep, Mult 10,12,15,19
50.04 2 2acoA VCA Rep, Mult 34,95,96
60.02 1 2atpB III Rep, Mult 18,19,45,109
70.02 1 3dr2B CA Rep, Mult 5,6,23
80.02 1 2qfpB NDG Rep, Mult 1,8,11,15
90.02 1 3ig8A MG Rep, Mult 37,91
100.02 1 1d7bA HEM Rep, Mult 62,65
110.02 1 1kejA CO Rep, Mult 50,56
120.02 1 3pddA CA Rep, Mult 19,112
130.02 1 1llrD UUU Rep, Mult 98,99
140.02 1 1wmdA CA Rep, Mult 71,73,75,78,79
150.02 1 3pyrV MG Rep, Mult 13,23
160.02 1 5hpmC CY3 Rep, Mult 26,115
170.02 1 1h3wM BMA Rep, Mult 24,26,41,43,87
180.02 1 1mcoH GUP Rep, Mult 19,24,25,114
190.02 1 2w4yA CA Rep, Mult 45,50

Download the all possible binding ligands and detailed prediction summary.
Download the templates clustering results.
(a)C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)Cluster size is the total number of templates in a cluster.
(c)Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column.
Mult is the complex structures with all potential binding ligands in the cluster.

  Enzyme Commission (EC) numbers and active sites

RankCscoreECPDB
Hit		TM-scoreRMSDaIDENaCovEC NumberActive Site Residues
10.1242dleA0.5103.110.1220.7063.1.3.4824,89,94
20.0662djmA0.5543.160.0730.8073.2.1.3110
30.0662bk8A0.5172.870.0600.6892.7.11.1NA
40.0662eo1A0.4973.480.0660.7062.7.11.1NA
50.0662gg1A0.4973.470.1240.6982.7.7.48,3.4.21.9142,54
60.0662rq8A0.5202.700.0360.6892.7.11.130,90
70.0601ogpA0.5953.750.0730.8741.8.3.1NA
80.0601yq2A0.5463.680.1270.8403.2.1.23NA
90.0602je8B0.5733.650.0730.8573.2.1.25NA
100.0601soxA0.5903.790.0890.8821.8.3.1NA
110.0601eurA0.3345.010.0720.6553.2.1.18NA
120.0601g0dA0.5633.540.0460.8072.3.2.13NA
130.0602biiA0.5673.970.0890.8991.7.1.3110
140.0601eutA0.5573.590.0960.8403.2.1.18NA
150.0601wmrA0.5423.000.0440.7563.2.1.5733,97
160.0601j0hA0.5782.870.1630.7653.2.1.135NA
170.0602amuA0.5463.440.0900.7981.15.1.2NA
180.0601izjA0.6102.910.1070.7983.2.1.135,3.2.1.1NA
190.0601xzwB0.5843.600.0750.8573.1.3.2NA
200.0601bglA0.5953.710.0880.8913.2.1.23NA
210.0601ea9C0.5692.860.1400.7653.2.1.54NA
220.0601zv5A0.5233.300.1100.7653.2.1.1721,23,72
230.0601eusA0.3375.020.0740.6643.2.1.18NA
240.0603gm8A0.5523.700.0870.8403.2.1.-NA
250.0603fn9C0.5854.010.1230.9083.2.1.2382

(a)CscoreEC is the confidence score for the EC number prediction. CscoreEC values range in between [0-1];
where a higher score indicates a more reliable EC number prediction.
(b)TM-score is a measure of global structural similarity between query and template protein.
(c)RMSDa is the RMSD between residues that are structurally aligned by TM-align.
(d)IDENa is the percentage sequence identity in the structurally aligned region.
(e)Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided
by length of the query protein.

  Gene Ontology (GO) terms

Homologous GO templates in PDB 
RankCscoreGOTM-scoreRMSDaIDENaCovPDB HitAssociated GO Terms
00.250.5592.820.170.723cnkA GO:0001664 GO:0001948 GO:0002576 GO:0003779 GO:0004871 GO:0005576 GO:0005634 GO:0005730 GO:0005737 GO:0005829 GO:0005856 GO:0005884 GO:0005886 GO:0005911 GO:0005913 GO:0005925 GO:0005938 GO:0007195 GO:0008134 GO:0015629 GO:0016020 GO:0016479 GO:0017048 GO:0017160 GO:0019900 GO:0030030 GO:0030168 GO:0030334 GO:0030863 GO:0031012 GO:0031267 GO:0031523 GO:0031532 GO:0031852 GO:0031941 GO:0032403 GO:0034329 GO:0034394 GO:0034988 GO:0042177 GO:0042384 GO:0042789 GO:0042803 GO:0042993 GO:0043025 GO:0043066 GO:0043113 GO:0043123 GO:0043198 GO:0043234 GO:0043433 GO:0044319 GO:0044822 GO:0045184 GO:0046332 GO:0048365 GO:0048471 GO:0050821 GO:0051015 GO:0051020 GO:0051220 GO:0051764 GO:0070062 GO:0070527 GO:0071526 GO:0090307 GO:0097440 GO:0098641 GO:1900026 GO:2001046
10.190.5782.810.170.762dmbA GO:0001725 GO:0003334 GO:0003382 GO:0003779 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005903 GO:0005913 GO:0005925 GO:0005938 GO:0007016 GO:0007165 GO:0007275 GO:0007517 GO:0007519 GO:0015629 GO:0016021 GO:0030018 GO:0030036 GO:0030154 GO:0031012 GO:0042802 GO:0044822 GO:0070062 GO:0098609 GO:0098641
20.190.5842.790.120.762diaA GO:0001725 GO:0003334 GO:0003382 GO:0003779 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005903 GO:0005913 GO:0005925 GO:0005938 GO:0007016 GO:0007165 GO:0007275 GO:0007517 GO:0007519 GO:0015629 GO:0016021 GO:0030018 GO:0030036 GO:0030154 GO:0031012 GO:0042802 GO:0044822 GO:0070062 GO:0098609 GO:0098641
30.160.5902.530.120.752dj4A GO:0001725 GO:0003334 GO:0003382 GO:0003779 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005903 GO:0005913 GO:0005925 GO:0005938 GO:0007016 GO:0007165 GO:0007275 GO:0007517 GO:0007519 GO:0015629 GO:0016021 GO:0030018 GO:0030036 GO:0030154 GO:0031012 GO:0042802 GO:0044822 GO:0070062 GO:0098609 GO:0098641
40.140.5732.910.140.762e9jA GO:0001725 GO:0003334 GO:0003382 GO:0003779 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005903 GO:0005913 GO:0005925 GO:0005938 GO:0007016 GO:0007165 GO:0007275 GO:0007517 GO:0007519 GO:0015629 GO:0016021 GO:0030018 GO:0030036 GO:0030154 GO:0031012 GO:0042802 GO:0044822 GO:0070062 GO:0098609 GO:0098641
50.130.5772.960.100.762ds4A GO:0005622 GO:0005634 GO:0005654 GO:0005737 GO:0008270 GO:0045171 GO:0046872 GO:0060348
60.100.6512.810.100.872eefA GO:0000164 GO:0004721 GO:0005975 GO:0005977 GO:0005979 GO:0005981 GO:0006470 GO:0019888 GO:0019899 GO:0042587 GO:0043231 GO:0050790
70.090.5772.670.110.752d7mA GO:0003779 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005925 GO:0008092 GO:0016020 GO:0016528 GO:0030018 GO:0030506 GO:0034329 GO:0042383 GO:0043034 GO:0048747 GO:0051015
80.080.6373.500.060.933p2dA GO:0002092 GO:0005634 GO:0005737 GO:0005886 GO:0005905 GO:0006810 GO:0007165 GO:0009968 GO:0015031 GO:0016020 GO:0016023 GO:0030139 GO:0031410
90.080.6313.000.090.863gc3A GO:0000785 GO:0001934 GO:0002031 GO:0002092 GO:0005096 GO:0005159 GO:0005622 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0005886 GO:0005905 GO:0006351 GO:0006355 GO:0006366 GO:0006810 GO:0006915 GO:0007165 GO:0007602 GO:0008134 GO:0008277 GO:0009968 GO:0015031 GO:0016020 GO:0016023 GO:0016567 GO:0031143 GO:0031397 GO:0031410 GO:0031434 GO:0031625 GO:0031701 GO:0032088 GO:0032092 GO:0032715 GO:0032717 GO:0033138 GO:0035025 GO:0035066 GO:0035774 GO:0042995 GO:0043027 GO:0043149 GO:0043154 GO:0043161 GO:0043547 GO:0044212 GO:0045944 GO:0070374 GO:0090240
100.080.5672.820.110.743rghA GO:0001664 GO:0001948 GO:0002576 GO:0003779 GO:0004871 GO:0005576 GO:0005634 GO:0005730 GO:0005737 GO:0005829 GO:0005856 GO:0005884 GO:0005886 GO:0005911 GO:0005913 GO:0005925 GO:0005938 GO:0007195 GO:0008134 GO:0015629 GO:0016020 GO:0016479 GO:0017048 GO:0017160 GO:0019900 GO:0030030 GO:0030168 GO:0030334 GO:0030863 GO:0031012 GO:0031267 GO:0031523 GO:0031532 GO:0031852 GO:0031941 GO:0032403 GO:0034329 GO:0034394 GO:0034988 GO:0042177 GO:0042384 GO:0042789 GO:0042803 GO:0042993 GO:0043025 GO:0043066 GO:0043113 GO:0043123 GO:0043198 GO:0043234 GO:0043433 GO:0044319 GO:0044822 GO:0045184 GO:0046332 GO:0048365 GO:0048471 GO:0050821 GO:0051015 GO:0051020 GO:0051220 GO:0051764 GO:0070062 GO:0070527 GO:0071526 GO:0090307 GO:0097440 GO:0098641 GO:1900026 GO:2001046
110.070.5902.780.120.764umgA GO:0004842 GO:0005622 GO:0005737 GO:0007275 GO:0007276 GO:0008270 GO:0009957 GO:0040034 GO:0042787 GO:0044268 GO:0045138 GO:0045604 GO:0046872
120.070.6143.710.110.942wtrB GO:0000785 GO:0001934 GO:0002031 GO:0002092 GO:0005096 GO:0005159 GO:0005622 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0005886 GO:0005905 GO:0006351 GO:0006355 GO:0006366 GO:0006810 GO:0006915 GO:0007165 GO:0007602 GO:0008134 GO:0008277 GO:0009968 GO:0015031 GO:0016020 GO:0016023 GO:0016567 GO:0031143 GO:0031397 GO:0031410 GO:0031434 GO:0031625 GO:0031701 GO:0032088 GO:0032092 GO:0032715 GO:0032717 GO:0033138 GO:0035025 GO:0035066 GO:0035774 GO:0042995 GO:0043027 GO:0043149 GO:0043154 GO:0043161 GO:0043547 GO:0044212 GO:0045944 GO:0070374 GO:0090240
130.070.5692.850.110.741v05A GO:0003779 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005925 GO:0008092 GO:0016020 GO:0016528 GO:0030018 GO:0030506 GO:0034329 GO:0042383 GO:0043034 GO:0048747 GO:0051015
140.070.6373.290.070.894jqiA GO:0000187 GO:0000785 GO:0001664 GO:0001933 GO:0001934 GO:0002031 GO:0002032 GO:0002092 GO:0005096 GO:0005159 GO:0005622 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0005886 GO:0005905 GO:0006351 GO:0006355 GO:0006366 GO:0006810 GO:0006897 GO:0006915 GO:0007165 GO:0007186 GO:0007188 GO:0007602 GO:0008134 GO:0008277 GO:0009968 GO:0014069 GO:0015031 GO:0016020 GO:0016023 GO:0016323 GO:0016567 GO:0019233 GO:0030276 GO:0030331 GO:0030817 GO:0030820 GO:0031143 GO:0031397 GO:0031398 GO:0031410 GO:0031434 GO:0031625 GO:0031691 GO:0031692 GO:0031701 GO:0031762 GO:0031896 GO:0032088 GO:0032092 GO:0032715 GO:0032717 GO:0033138 GO:0034260 GO:0034393 GO:0035025 GO:0035066 GO:0035612 GO:0035615 GO:0035774 GO:0042493 GO:0042699 GO:0042995 GO:0043027 GO:0043149 GO:0043154 GO:0043161 GO:0043197 GO:0043280 GO:0043547 GO:0044212 GO:0044325 GO:0045211 GO:0045309 GO:0045944 GO:0050975 GO:0051219 GO:0070373 GO:0070374 GO:0090240
150.070.6163.660.070.941sujA GO:0007165
160.070.5612.850.120.742eedA GO:0001725 GO:0003334 GO:0003382 GO:0003779 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005903 GO:0005913 GO:0005925 GO:0005938 GO:0007016 GO:0007165 GO:0007275 GO:0007517 GO:0007519 GO:0015629 GO:0016021 GO:0030018 GO:0030036 GO:0030154 GO:0031012 GO:0042802 GO:0044822 GO:0070062 GO:0098609 GO:0098641
170.070.5752.690.150.752d7pA GO:0003779 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005925 GO:0008092 GO:0016020 GO:0016528 GO:0030018 GO:0030506 GO:0034329 GO:0042383 GO:0043034 GO:0048747 GO:0051015
180.070.5773.880.050.904b5zA GO:0005576 GO:0005618 GO:0007155 GO:0009405 GO:0016020
190.070.6123.450.100.892m83A GO:0005975 GO:0005977 GO:0016020 GO:0016021
200.070.5662.550.120.742eebA GO:0001725 GO:0003334 GO:0003382 GO:0003779 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005903 GO:0005913 GO:0005925 GO:0005938 GO:0007016 GO:0007165 GO:0007275 GO:0007517 GO:0007519 GO:0015629 GO:0016021 GO:0030018 GO:0030036 GO:0030154 GO:0031012 GO:0042802 GO:0044822 GO:0070062 GO:0098609 GO:0098641
210.070.6223.420.050.921cf1C GO:0001750 GO:0001917 GO:0002046 GO:0005829 GO:0007165 GO:0007601 GO:0022400 GO:0050896 GO:0051219
220.070.5532.870.100.732dicA GO:0001725 GO:0003334 GO:0003382 GO:0003779 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005903 GO:0005913 GO:0005925 GO:0005938 GO:0007016 GO:0007165 GO:0007275 GO:0007517 GO:0007519 GO:0015629 GO:0016021 GO:0030018 GO:0030036 GO:0030154 GO:0031012 GO:0042802 GO:0044822 GO:0070062 GO:0098609 GO:0098641
230.070.5353.030.110.722k3tA GO:0001664 GO:0001948 GO:0002576 GO:0003779 GO:0004871 GO:0005576 GO:0005634 GO:0005730 GO:0005737 GO:0005829 GO:0005856 GO:0005884 GO:0005886 GO:0005911 GO:0005913 GO:0005925 GO:0005938 GO:0007195 GO:0008134 GO:0015629 GO:0016020 GO:0016479 GO:0017048 GO:0017160 GO:0019900 GO:0030030 GO:0030168 GO:0030334 GO:0030863 GO:0031012 GO:0031267 GO:0031523 GO:0031532 GO:0031852 GO:0031941 GO:0032403 GO:0034329 GO:0034394 GO:0034988 GO:0042177 GO:0042384 GO:0042789 GO:0042803 GO:0042993 GO:0043025 GO:0043066 GO:0043113 GO:0043123 GO:0043198 GO:0043234 GO:0043433 GO:0044319 GO:0044822 GO:0045184 GO:0046332 GO:0048365 GO:0048471 GO:0050821 GO:0051015 GO:0051020 GO:0051220 GO:0051764 GO:0070062 GO:0070527 GO:0071526 GO:0090307 GO:0097440 GO:0098641 GO:1900026 GO:2001046
240.070.5854.100.070.912ralA GO:0005576 GO:0005618 GO:0007155 GO:0009405 GO:0016020 GO:0046872
250.070.5834.060.070.911r17A GO:0005576 GO:0005618 GO:0007155 GO:0009405 GO:0016020 GO:0046872
260.070.5933.040.150.792dibA GO:0001725 GO:0003334 GO:0003382 GO:0003779 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005903 GO:0005913 GO:0005925 GO:0005938 GO:0007016 GO:0007165 GO:0007275 GO:0007517 GO:0007519 GO:0015629 GO:0016021 GO:0030018 GO:0030036 GO:0030154 GO:0031012 GO:0042802 GO:0044822 GO:0070062 GO:0098609 GO:0098641
270.070.5362.850.100.722ee6A GO:0001725 GO:0003334 GO:0003382 GO:0003779 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005903 GO:0005913 GO:0005925 GO:0005938 GO:0007016 GO:0007165 GO:0007275 GO:0007517 GO:0007519 GO:0015629 GO:0016021 GO:0030018 GO:0030036 GO:0030154 GO:0031012 GO:0042802 GO:0044822 GO:0070062 GO:0098609 GO:0098641
280.070.5504.170.070.884mboA GO:0005576 GO:0005618 GO:0007155 GO:0009986 GO:0030260 GO:1990254
290.070.5572.990.050.794bfnA GO:0003824 GO:0004339 GO:0005976
300.070.5243.050.100.722eeaA GO:0001725 GO:0003334 GO:0003382 GO:0003779 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005903 GO:0005913 GO:0005925 GO:0005938 GO:0007016 GO:0007165 GO:0007275 GO:0007517 GO:0007519 GO:0015629 GO:0016021 GO:0030018 GO:0030036 GO:0030154 GO:0031012 GO:0042802 GO:0044822 GO:0070062 GO:0098609 GO:0098641
310.070.5592.810.130.732di8A GO:0001725 GO:0003334 GO:0003382 GO:0003779 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005903 GO:0005913 GO:0005925 GO:0005938 GO:0007016 GO:0007165 GO:0007275 GO:0007517 GO:0007519 GO:0015629 GO:0016021 GO:0030018 GO:0030036 GO:0030154 GO:0031012 GO:0042802 GO:0044822 GO:0070062 GO:0098609 GO:0098641
320.070.5363.170.090.742d7oA GO:0003779 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005925 GO:0008092 GO:0016020 GO:0016528 GO:0030018 GO:0030506 GO:0034329 GO:0042383 GO:0043034 GO:0048747 GO:0051015
330.070.5573.510.060.843gd1E GO:0000785 GO:0001934 GO:0002031 GO:0002092 GO:0005096 GO:0005159 GO:0005622 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0005886 GO:0005905 GO:0006351 GO:0006355 GO:0006366 GO:0006810 GO:0006915 GO:0007165 GO:0007602 GO:0008134 GO:0008277 GO:0009968 GO:0015031 GO:0016020 GO:0016023 GO:0016567 GO:0031143 GO:0031397 GO:0031410 GO:0031434 GO:0031625 GO:0031701 GO:0032088 GO:0032092 GO:0032715 GO:0032717 GO:0033138 GO:0035025 GO:0035066 GO:0035774 GO:0042995 GO:0043027 GO:0043149 GO:0043154 GO:0043161 GO:0043547 GO:0044212 GO:0045944 GO:0070374 GO:0090240
340.070.5012.920.100.682e9iA GO:0001725 GO:0003334 GO:0003382 GO:0003779 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005903 GO:0005913 GO:0005925 GO:0005938 GO:0007016 GO:0007165 GO:0007275 GO:0007517 GO:0007519 GO:0015629 GO:0016021 GO:0030018 GO:0030036 GO:0030154 GO:0031012 GO:0042802 GO:0044822 GO:0070062 GO:0098609 GO:0098641
350.070.5144.110.060.822xtlB GO:0005618 GO:0016020 GO:0016021
360.070.5993.850.050.943au0A GO:0005576 GO:0005618 GO:0007155 GO:0009405 GO:0016020
370.070.4933.710.060.763irpX GO:0005576 GO:0005618 GO:0007155 GO:0009405 GO:0016020
380.070.6143.750.090.914jdzB GO:0005576 GO:0005618 GO:0007155 GO:0016020 GO:0016021
390.070.5713.970.040.914mbrA GO:0005576 GO:0005618 GO:0007155


Consensus prediction of GO terms		 
Molecular Function GO:0003779 GO:0098641 GO:0044822 GO:0042802 GO:0046983 GO:0097367 GO:0017048 GO:0034987 GO:0031628 GO:0032403
GO-Score 0.64 0.64 0.64 0.53 0.49 0.49 0.49 0.49 0.49 0.49
Biological Processes GO:0007519 GO:0003382 GO:0003334 GO:0007016 GO:2000145 GO:0042307 GO:0051090 GO:1902850 GO:0034330 GO:0045055 GO:0010927 GO:0051225 GO:0016477 GO:0006366 GO:0030168 GO:0044782 GO:0042981 GO:0045892 GO:0034109 GO:0007212 GO:2001044 GO:0051248 GO:0010770 GO:0042990 GO:0007015 GO:0090505 GO:0051668 GO:0006356 GO:0060271 GO:0072657 GO:0031647 GO:0010811 GO:0007193 GO:0030031 GO:0009895 GO:0043069 GO:1900024 GO:0009299 GO:0043122 GO:0044092 GO:0042176 GO:1902533
GO-Score 0.53 0.53 0.53 0.53 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49
Cellular Component GO:0005925 GO:0005886 GO:0031012 GO:0005829 GO:0005913 GO:0070062 GO:0001725 GO:0030018 GO:0016021 GO:0005903 GO:0044463 GO:0044427 GO:0044297 GO:0031981 GO:0005884 GO:0030425 GO:0044448 GO:0043234
GO-Score 0.64 0.64 0.64 0.64 0.64 0.64 0.53 0.53 0.53 0.53 0.49 0.49 0.49 0.49 0.49 0.49 0.49 0.49

(a)CscoreGO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)TM-score is a measure of global structural similarity between query and template protein.
(c)RMSDa is the RMSD between residues that are structurally aligned by TM-align.
(d)IDENa is the percentage sequence identity in the structurally aligned region.
(e)Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on CscoreGO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]


Please cite the following articles when you use the I-TASSER server:
1. J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2. J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.