I-TASSER results

Input Sequence in FASTA format

>protein (166 residues)
MPKLSAGVLLYRARAGVVDVLLAHPGGPFWAGKDDGAWSIPKGEYTGGEDPWLAARREFS
EEIGLCVPDGPRIDFGSLKQSGGKVVTVFGVRADLDITDARSSTFELDWPKGSGKMRKFP
EVDRVSWFPVARARTKLLKGQRGFLDRLMAHPAVAGLSEGPESLPR

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 \| \| \| \| \| \| \| \| MPKLSAGVLLYRARAGVVDVLLAHPGGPFWAGKDDGAWSIPKGEYTGGEDPWLAARREFSEEIGLCVPDGPRIDFGSLKQSGGKVVTVFGVRADLDITDARSSTFELDWPKGSGKMRKFPEVDRVSWFPVARARTKLLKGQRGFLDRLMAHPAVAGLSEGPESLPR
Prediction	CCEEEEEEEEEHCCCCEEEEEEEEHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEHCCCCEEEEEEEEEHCCCCCEEEEEEEEEEHCCCCCCCCCCHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
Conf.Score	9758999999956799689999985787667788998667776789999999999999999989855665788779998689879999999865776556789999987688887778856766435999999986885589999999998666576666455589
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 \| \| \| \| \| \| \| \| MPKLSAGVLLYRARAGVVDVLLAHPGGPFWAGKDDGAWSIPKGEYTGGEDPWLAARREFSEEIGLCVPDGPRIDFGSLKQSGGKVVTVFGVRADLDITDARSSTFELDWPKGSGKMRKFPEVDRVSWFPVARARTKLLKGQRGFLDRLMAHPAVAGLSEGPESLPR
Prediction	7442000000014476311000013444334444432021244424661412300210030114030443321412314244443220001313343342432212031255655345362033124031630362035542400430272255433463565368
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160

                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCEEEEEEEEEHCCCCEEEEEEEEHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEHCCCCEEEEEEEEEHCCCCCEEEEEEEEEEHCCCCCCCCCCHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
MPKLSAGVLLYRARAGVVDVLLAHPGGPFWAGKDDGAWSIPKGEYTGGEDPWLAARREFSEEIGLCVPDGPRIDFGSLKQSGGKVVTVFGVRADLDITDARSSTFELDWPKGSGKMRKFPEVDRVSWFPVARARTKLLKGQRGFLDRLMAHPAVAGLSEGPESLPR

1ktgA

0.22

0.18

0.82

2.47

MUSTER

V-VKAAGLVIYRKLAGKIEFLLLQA------SYPPHHWTPPKGHVDPGEDEWQAAIRETKEEANITKEQLTIHEDCHETLFYEAK------------GKPKSVKYWLAKLNNPDDVQLSHEHQNWKWCELEDAIKIAYAEMGSLLRKFSAFLAGF-----------

1ktgA

0.22

0.18

0.82

2.92

dPPAS

-VVKAAGLVIYRKLAGKIEFLLLQA------SYPPHHWTPPKGHVDPGEDEWQAAIRETKEEANITKEQLTIHEDCHETLFYEAK------------GKPKSVKYWLAKLNNPDDVQLSHEHQNWKWCELEDAIKIAYAEMGSLLRKFSAFLAGF-----------

1ktgA

0.21

0.17

0.81

3.41

wdPPAS

-VVKAAGLVIYRKLAGKIEFLLLQA------SYPPHHWTPPKGHVDPGEDEWQAAIRETKEEANITKEQLTIHEDCHETLFYEA------------GKPKSVKYWLAKLNNPD-DVQLSHEHQNWKWCELEDAIKIAYAEMGSLLRKFSAFLAGF-----------

1ktgA

0.21

0.17

0.81

3.12

wMUSTER

--VKAAGLVIYRKLAGKIEFLLLQA------SYPPHHWTPPKGHVDPGEDEWQAAIRETKEEANITKEQLTIHEDCHETLFYEAK-----------GKPKSVKYWLAKLNN-PDDVQLSHEHQNWKWCELEDAIKIAYAEMGSLLRKFSAFLAGF-----------

1ktgA

0.21

0.17

0.81

3.67

wPPAS

V-VKAAGLVIYRKLAGKIEFLLLQA------SYPPHHWTPPKGHVDPGEDEWQAAIRETKEEANITKEQLTIHEDCHETLFYEA------------GKPKSVKYWLAKLNNPD-DVQLSHEHQNWKWCELEDAIKIADAEMGSLLRKFSAFLAGF-----------

1ktgA

0.23

0.19

0.82

4.36

dPPAS2

-VVKAAGLVIYRKLAGKIEFLLLQA------SYPPHHWTPPKGHVDPGEDEWQAAIRETKEEANITKEQ---------LTIHEDCHETLFYEAKG---KPKSVKYWLAKLNNPDDVQLSHEHQNWKWCELEDAIKIAYAEMGSLLRKFSAFLAGF-----------

1ktgA

0.22

0.18

0.82

3.24

PPAS

V-VKAAGLVIYRKLAGKIEFLLLQA------SYPPHHWTPPKGHVDPGEDEWQAAIRETKEEANITKEQLTIHEDCHETLFYEAK------------GKPKSVKYWLAKLNNPDDVQLSHEHQNWKWCELEDAIKIADAEMGSLLRKFSAFLAGF-----------

4ilqA

0.19

0.16

0.85

3.09

Env-PPAS

THEYSFGVIPIRFDRSTLKACFICH-------TDGKHWGFPKGHAEEKEGPQEAAERELVEETGL-----GIVNFFPKI----FVENYSFNDKEEIFVRKEVTYFLAEV--KGEVHADPDEICDVQWLSFQEGLRLLNPEIRNIVTEADKFVQSYLFAS-------

1xscA

0.17

0.14

0.85

2.41

MUSTER

MALRACGLIIFRRCLNAIEFLLLQA------SDGIHHWTPPKGHVEPGEDDLETALRATQEEAGIEAGQLTIIEGFKRELNYVA-----------RNKPKTVIYWLAEVKDYDVEIRLSHEHQAYRWLGLEEACQLAQKEMKAALQEGHQFLCSIEAL--------

1xscA

0.16

0.14

0.85

2.81

dPPAS

MALRACGLIIFRRDNNAIEFLLLQA------SDGIHHWTPPKGHVEPGEDDLETALRATQEEAGIEAGQL-----------TIIEGFKRELNYVARNKPKTVIYWLAEVKDYDVEIRLSHEHQAYRWLGLEEACQLAQKEMKAALQEGHQFLCSIEAL--------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-0.13

Estimated TM-score = 0.70±0.12

Estimated RMSD = 5.2±3.4Å

Download Model 2

C-score=-1.93

Download Model 3

C-score=-2.71

Download Model 4

C-score=-1.10

Download Model 5

C-score=-2.81

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	1ktgA	0.785	1.29	0.206	0.819
2	1xscA	0.772	1.79	0.177	0.849
3	5cfiA	0.750	1.81	0.162	0.819
4	3sonA	0.716	2.70	0.154	0.855
5	3fjyB	0.714	2.94	0.164	0.849
6	2fmlA	0.704	3.07	0.128	0.868
7	4ilqA	0.697	2.51	0.179	0.813
8	2o1cA	0.695	2.57	0.203	0.825
9	2kdwA	0.687	3.21	0.141	0.868
10	3gz6A	0.684	3.21	0.153	0.868

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.63	68	2a8pA	MN	Rep, Mult	42,43,58,62,121
2	0.07	12	5ansA	RX8	Rep, Mult	5,6,7,25,39,40,42,43,82,100,138,140,141
3	0.04	8	2a8sA	GTP	Rep, Mult	7,25,40,42,43,44,58,61,62,102,121,140,141,144
4	0.02	4	3shdI	MN	Rep, Mult	57,58,61
5	0.02	3	2qjtB	MN	Rep, Mult	44,57,58
6	0.01	1	2o1cC	PPV	Rep, Mult	42,43,44,58,92
7	0.01	2	1ktgA	AMP	Rep, Mult	37,42,102,139
8	0.01	3	1sz3B	GNP	Rep, Mult	3,5,42,43,44,98,100,102
9	0.01	2	1ktgA	MG	Rep, Mult	19,129
10	0.00	1	4s2yA	NUC	Rep, Mult	3,25,34,37,42,43,44,58,62,82,100,121

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.342	2q9pA	0.615	2.53	0.225	0.723	3.6.1.52	9,58,62
2	0.095	2w4eA	0.599	3.06	0.163	0.759	3.6.1.13	12
3	0.067	1v8mA	0.601	3.28	0.231	0.765	3.6.1.13	NA
4	0.067	2yvmA	0.625	3.01	0.193	0.795	3.6.1.-	NA
5	0.067	1hx3B	0.642	3.53	0.135	0.843	5.3.3.2	62
6	0.066	1mqwA	0.624	3.28	0.173	0.801	3.6.1.13	NA
7	0.066	2dsbA	0.594	3.58	0.146	0.789	3.6.1.13	146
8	0.060	1u60C	0.428	4.75	0.059	0.717	3.5.1.2	23,25,28
9	0.060	1q33A	0.670	2.79	0.154	0.813	3.6.1.13	48,58,61
10	0.060	2a96B	0.409	4.99	0.045	0.675	3.1.3.2	NA
11	0.060	1zs6B	0.404	4.23	0.056	0.621	2.7.4.6	NA
12	0.060	1viqA	0.658	2.75	0.200	0.807	3.6.1.13	58,61,64,124
13	0.060	1viuB	0.599	3.23	0.145	0.765	3.6.1.-	NA
14	0.060	2wj2A	0.418	5.19	0.048	0.747	3.5.1.99	39
15	0.060	1hbmA	0.414	5.23	0.040	0.723	2.8.4.1	NA
16	0.060	3hyqA	0.635	3.03	0.139	0.801	5.3.3.2	62
17	0.060	1b7bA	0.433	4.83	0.034	0.717	2.7.2.2	NA
18	0.060	2r5wB	0.671	2.59	0.127	0.807	2.7.7.1	38,138
19	0.060	2pnyA	0.662	3.17	0.105	0.843	5.3.3.2	64
20	0.060	3czdA	0.436	4.71	0.056	0.717	3.5.1.2	64
21	0.060	1zs6A	0.406	4.41	0.055	0.632	2.7.4.6	NA
22	0.060	2e9yA	0.420	5.04	0.048	0.717	2.7.2.2	NA
23	0.060	1e6vA	0.421	5.21	0.040	0.729	2.8.4.1	NA
24	0.060	2j0lA	0.297	5.05	0.036	0.494	2.7.10.2	19
25	0.060	1f3yA	0.658	3.06	0.200	0.813	3.6.1.17	58,62,105
26	0.060	1xsbA	0.772	1.99	0.170	0.849	3.6.1.17	42,62

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.50	0.785	1.29	0.21	0.82	1ktgA	GO:0000166 GO:0004081 GO:0005524 GO:0006167 GO:0006172 GO:0006754 GO:0006915 GO:0008796 GO:0015967 GO:0016787 GO:0019693 GO:0043135
1	0.43	0.750	1.81	0.16	0.82	5cfiA	GO:0004081 GO:0008796 GO:0016787
2	0.42	0.622	2.98	0.18	0.78	3cngC	GO:0016787 GO:0046872
3	0.41	0.725	2.81	0.15	0.87	3sonA	GO:0016787
4	0.35	0.565	2.78	0.23	0.68	3smdA	GO:0016020 GO:0016021 GO:0016787
5	0.34	0.520	3.72	0.12	0.72	1mutA	GO:0000287 GO:0006260 GO:0006281 GO:0006974 GO:0008413 GO:0016787 GO:0030145 GO:0035539 GO:0044715 GO:0044716 GO:0046872 GO:0047693
6	0.33	0.695	2.57	0.20	0.83	2o1cA	GO:0000287 GO:0008828 GO:0016787 GO:0019177 GO:0046654 GO:0046656 GO:0046872
7	0.32	0.590	2.95	0.14	0.73	2b06A	GO:0016787
8	0.32	0.713	2.43	0.19	0.82	4mpoB	GO:0016787
9	0.31	0.643	2.79	0.22	0.77	5hzxA	GO:0006281 GO:0008413 GO:0016787
10	0.31	0.709	2.97	0.16	0.87	2kdvA	GO:0005737 GO:0006402 GO:0016787 GO:0016818 GO:0034353 GO:0046872 GO:0050779
11	0.31	0.600	2.76	0.15	0.74	4v14A	GO:0006281 GO:0008413 GO:0016787
12	0.30	0.671	2.59	0.13	0.81	2r5wB	GO:0000166 GO:0000309 GO:0003824 GO:0009058 GO:0016740 GO:0016779 GO:0016787 GO:0046872
13	0.30	0.637	3.02	0.18	0.78	3gg6A	GO:0000287 GO:0005829 GO:0009117 GO:0016787 GO:0034656 GO:0044715 GO:0044716 GO:0044717 GO:0046057 GO:0046067 GO:0046712 GO:0046872
14	0.30	0.640	2.85	0.17	0.81	2jvbA	GO:0000184 GO:0000290 GO:0000932 GO:0003682 GO:0003723 GO:0003729 GO:0005634 GO:0005737 GO:0006397 GO:0016787 GO:0030145 GO:0031087 GO:0034063 GO:0046872 GO:0050072 GO:0060261
15	0.28	0.561	3.00	0.20	0.69	3id9B	GO:0016787
16	0.26	0.585	3.30	0.17	0.77	4jzsA	GO:0016787 GO:0046872
17	0.26	0.618	2.66	0.15	0.74	2a6tB	GO:0000166 GO:0000287 GO:0000290 GO:0000340 GO:0000932 GO:0003723 GO:0003727 GO:0005524 GO:0005634 GO:0005737 GO:0005829 GO:0005845 GO:0006397 GO:0010494 GO:0016787 GO:0030145 GO:0031087 GO:0046872 GO:0050072 GO:0098745
18	0.26	0.580	3.15	0.15	0.74	3q91B	GO:0005737 GO:0005829 GO:0008768 GO:0016787 GO:0016818 GO:0018279 GO:0046872 GO:0047631 GO:0070062
19	0.25	0.586	3.47	0.14	0.77	3q91D	GO:0005737 GO:0005829 GO:0008768 GO:0016787 GO:0016818 GO:0018279 GO:0046872 GO:0047631 GO:0070062
20	0.25	0.641	2.91	0.16	0.79	2b0vA	GO:0016787
21	0.25	0.711	3.10	0.15	0.88	2fmlA	GO:0016787
22	0.25	0.627	3.10	0.16	0.78	3hhjB	GO:0006281 GO:0008413 GO:0016787
23	0.24	0.617	2.72	0.16	0.73	4s2vA	GO:0005737 GO:0006402 GO:0016787 GO:0016818 GO:0034353 GO:0046872 GO:0050779
24	0.24	0.618	3.11	0.17	0.77	4kyxA	GO:0016787
25	0.23	0.615	2.81	0.16	0.75	3fk9A	GO:0016787
26	0.23	0.663	2.06	0.26	0.75	1vc8A	GO:0000166 GO:0005524 GO:0016787 GO:0016818 GO:0046872
27	0.23	0.662	2.47	0.13	0.78	3dkuA	GO:0016787
28	0.22	0.630	2.81	0.18	0.75	4dywA	GO:0016787
29	0.22	0.620	2.54	0.17	0.75	3f13B	GO:0016787
30	0.21	0.662	2.72	0.17	0.80	3grnA	GO:0016787
31	0.21	0.659	2.53	0.21	0.78	1su2A	GO:0000166 GO:0005524 GO:0016787
32	0.21	0.629	3.07	0.18	0.79	2rrkA	GO:0006281 GO:0016787
33	0.21	0.644	3.18	0.16	0.81	5bonA	GO:0005829 GO:0006203 GO:0008413 GO:0016787 GO:0017110 GO:0034656 GO:0035539 GO:0046872
34	0.21	0.631	2.57	0.13	0.76	3h95A	GO:0005634 GO:0005737 GO:0005739 GO:0008083 GO:0016787
35	0.20	0.627	2.81	0.13	0.77	4hfqA	GO:0016787
36	0.19	0.574	3.35	0.16	0.74	3exqA	GO:0016787
37	0.19	0.625	3.12	0.16	0.79	3o61D	GO:0000287 GO:0016787 GO:0016818 GO:0046872 GO:0052751
38	0.19	0.635	3.03	0.14	0.80	3hyqA	GO:0004452 GO:0005737 GO:0008299 GO:0016787 GO:0016853 GO:0046872 GO:0050992
39	0.17	0.612	3.15	0.16	0.77	3q4iA	GO:0016787
40	0.16	0.720	2.93	0.16	0.86	3fjyB	GO:0016787
41	0.15	0.765	2.00	0.17	0.84	1xsaA	GO:0000166 GO:0000302 GO:0004081 GO:0005525 GO:0005739 GO:0005759 GO:0006139 GO:0006915 GO:0008796 GO:0008803 GO:0016787
42	0.14	0.636	2.89	0.15	0.78	3j9me	GO:0003735 GO:0005654 GO:0005739 GO:0005743 GO:0005762 GO:0005840 GO:0016787 GO:0030054 GO:0030529 GO:0070125 GO:0070126
43	0.14	0.596	2.46	0.12	0.71	3gwyB	GO:0016787
44	0.12	0.640	2.38	0.18	0.75	1nqzA	GO:0016787
45	0.10	0.658	3.06	0.20	0.81	1f3yA	GO:0000166 GO:0004081 GO:0005524 GO:0016787
46	0.09	0.678	2.77	0.14	0.83	2qkmB	GO:0000166 GO:0000287 GO:0000290 GO:0000340 GO:0000932 GO:0003723 GO:0003727 GO:0005524 GO:0005634 GO:0005737 GO:0005829 GO:0005845 GO:0006397 GO:0010494 GO:0016787 GO:0030145 GO:0031087 GO:0046872 GO:0050072 GO:0098745
47	0.09	0.663	2.34	0.25	0.77	3i7uC	GO:0000166 GO:0005524 GO:0016787
48	0.08	0.636	2.93	0.17	0.77	1k2eA	GO:0016787
49	0.07	0.583	3.11	0.13	0.75	2pqvB	GO:0016787
50	0.07	0.639	3.43	0.13	0.83	2b2kB	GO:0004452 GO:0005737 GO:0006974 GO:0008299 GO:0016787 GO:0016853 GO:0046872 GO:0050992
51	0.07	0.608	3.29	0.13	0.78	1vhzA	GO:0000287 GO:0005829 GO:0016787 GO:0019144 GO:0046872

Consensus prediction of GO terms

Molecular Function	GO:0004081	GO:0043135	GO:0005524	GO:0046872
GO-Score	0.71	0.50	0.50	0.42
Biological Processes	GO:0015967	GO:0006915	GO:0006172	GO:0006167	GO:0006754
GO-Score	0.50	0.50	0.50	0.50	0.50
Cellular Component	GO:0016021
GO-Score	0.35

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv3733c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]