Threading Zmax Znorm MUSTER 6.00 1.03 dPPAS 16.54 1.78 wdPPAS 22.62 2.43 wMUSTER 7.45 1.28 wPPAS 13.49 1.93 dPPAS2 23.80 2.27 PPAS 9.39 1.34 Env-PPAS 14.13 1.77 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=20200) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -1.06 0.58+-0.14 8.8+-4.6 13763 0.200 model2 -3.55 731 0.017 model3 -2.55 2841 0.045 model4 -2.16 4320 0.067 model5 -3.65 971 0.015 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).