Threading Zmax Znorm MUSTER 5.10 0.88 dPPAS 8.82 0.95 wdPPAS 9.73 1.05 wMUSTER 6.04 1.04 wPPAS 7.74 1.11 dPPAS2 12.06 1.15 PPAS 7.45 1.06 Env-PPAS 6.47 0.81 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=20200) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -4.61 0.24+-0.07 14.9+-3.5 1664 0.010 model2 -4.74 1582 0.009 model3 -4.71 1283 0.009 model4 -5.00 1196 0.007 model5 -5.00 1138 0.006 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).