Threading Zmax Znorm MUSTER 3.83 0.66 dPPAS 8.24 0.89 wdPPAS 7.83 0.84 wMUSTER 3.94 0.68 wPPAS 4.59 0.66 dPPAS2 18.03 1.72 PPAS 4.88 0.70 Env-PPAS 6.61 0.83 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=12033) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.22 0.45+-0.15 11.6+-4.5 7538 0.125 model2 -3.28 2375 0.043 model3 -4.70 559 0.010 model4 -5.00 240 0.007 model5 -3.34 1897 0.041 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).