Threading Zmax Znorm MUSTER 5.49 0.95 dPPAS 6.85 0.74 wdPPAS 8.43 0.91 wMUSTER 6.53 1.13 wPPAS 11.33 1.62 dPPAS2 10.71 1.02 PPAS 10.68 1.53 Env-PPAS 8.50 1.06 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=6024) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.27 0.45+-0.14 12.5+-4.3 2259 0.093 model2 -2.16 753 0.103 model3 -3.62 753 0.024 model4 -3.24 702 0.035 model5 -4.51 192 0.010 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).