Threading Zmax Znorm MUSTER 5.92 1.02 dPPAS 9.90 1.06 wdPPAS 7.90 0.85 wMUSTER 6.39 1.10 wPPAS 6.67 0.95 dPPAS2 15.37 1.46 PPAS 6.25 0.89 Env-PPAS 8.51 1.06 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=19554) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -1.38 0.54+-0.15 5.4+-3.5 13678 0.240 model2 -3.04 2567 0.046 model3 -3.58 1007 0.026 model4 -2.57 3811 0.073 model5 -4.24 590 0.014 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).