I-TASSER results

Input Sequence in FASTA format

>protein (172 residues)
MSKIDRKNGVPSTLTTIPLADPHAGPAEPSIGDLIKDATTQMSTLVRAEVELARAEITRD
VKKGLTGSVFFISSLVVGFYSTFFFFFFVAELLDTWIWRWVAFLLVFAIMVVVTAVLALL
GFLKVRRIRGPRQTIASVKETRTALTPGHDKTPVTPKPVTSDRATPVDPSGW

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 \| \| \| \| \| \| \| \| MSKIDRKNGVPSTLTTIPLADPHAGPAEPSIGDLIKDATTQMSTLVRAEVELARAEITRDVKKGLTGSVFFISSLVVGFYSTFFFFFFVAELLDTWIWRWVAFLLVFAIMVVVTAVLALLGFLKVRRIRGPRQTIASVKETRTALTPGHDKTPVTPKPVTSDRATPVDPSGW
Prediction	CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
Conf.Score	9988998889988888899888999889999999999999999999999999999999999998868999999999999999999999999999999999999999999999999999999999987899999999999999998756677777667777778889999999
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 \| \| \| \| \| \| \| \| MSKIDRKNGVPSTLTTIPLADPHAGPAEPSIGDLIKDATTQMSTLVRAEVELARAEITRDVKKGLTGSVFFISSLVVGFYSTFFFFFFVAELLDTWIWRWVAFLLVFAIMVVVTAVLALLGFLKVRRIRGPRQTIASVKETRTALTPGHDKTPVTPKPVTSDRATPVDPSGW
Prediction	7555557553445345343444656486430140043027303510440152034303640441021001112123323333333332323233332333212222233333313202320243057254255215304512530464466554565454565544544757
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160

                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
MSKIDRKNGVPSTLTTIPLADPHAGPAEPSIGDLIKDATTQMSTLVRAEVELARAEITRDVKKGLTGSVFFISSLVVGFYSTFFFFFFVAELLDTWIWRWVAFLLVFAIMVVVTAVLALLGFLKVRRIRGPRQTIASVKETRTALTPGHDKTPVTPKPVTSDRATPVDPSGW

5an8A

0.08

1.00

0.71

MUSTER

LSRKFTEWCYGPVRVSLYDLASVDSWEENSVLEIIAFHSRSPHRHRMVVLEPLNKLLQAKWDRLIPRFCFNFLCYLVYMLIFTAVAYHQPALGNSMLLLGHILILLGGVYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQALLTVLSQVLCFLAIEWYLPLLVSSLVLGW

5cwdA

0.07

0.96

0.69

dPPAS

-------TKEDARSTCEKAARKAAESNDEEVAKQAAKDCLEVAKQAGMPTKEAARSFCEAAARAAAESNDEEVAKIAAKACLEVAKQAPTKEAARSFCEAAARAAAESNDEEVAKIAAKACLEVAKQAGMPTKEAARSFCEAAKRAAKESNDEEVEKIAKKACKEVAKQAGM

2lp4A1

0.09

0.08

0.83

0.76

wdPPAS

MSMDISD-----------------------YQTFFDEADELLADMEQHLLDLVP---AEQLNAIFRAAHSIKGGAGTFFTILQETTHLMENLLDEARR--LNTDIINLFLETKDIMQEQLDAYKNSEEPDAASFEYICNALRQLALEAKGETPSAVTRLSVVAKSEPQDEQ-

2uxwA

0.13

0.12

0.88

0.72

wMUSTER

LSGLGSALKNPFG-SGLSLSGLVHPE--SRSGELAVRALEQFATVVEAKLIKHKKGIVNE-----QFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEKMLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVER-------------GGVVTSNPLGF

5id3A

0.11

0.08

0.71

0.88

wPPAS

-------------MAALSVDEYKLSR-EKKLLLQLENAETLL-----APLHDAKRKIEQEAEAHTDRVAWAGFAASGVQTGLFARLTWWEY--------WPVTYFATYSTVAATFGYYLYTQQSFRRAQK-VTEVDELRNQLKRLRDPLE----------------------

5cwdA

0.07

0.96

0.98

dPPAS2

-------TKEDARSTCEKAARKAAESNDEEVAKQAAKDCLEVAKQAGMPTKEAARSFCEAAARAAAESNDEEVAKIAAKACLEVAKQAPTKEAARSFCEAAARAAAESNDEEVAKIAAKACLEVAKQAGMPEAARSFCEAAKRAAKESNDEEVEKIAKKACKEVAKQAGMPW

5cwdA

0.07

0.95

1.04

PPAS

-------TKEDARSTCEKAARKAAESNDEEVAKQAAKDCLEVAKQAGMPTKEAARSFCEAAARAAAESNDEEVAKIAAKACLEVAKQA-TKEAARSFCEAAARAAAESNDEEVAKIAAKACLEVAKQAGMPEAARSFCEAAKRAAKESNDEEVEKIAKKACKEVAKQAGMPW

3j1zP1

0.10

0.09

0.98

0.64

Env-PPAS

MTQTSQYDFWVKLASRASVATALTWLYSGSAS-MLASLTDSFADTLASIINFIAIRYAIVGHGKAEPLAALAQSAFIMGSAFLLLFYGGERLLNSPVENATLGVVVSVVAIVLTLALVLLQKRALAATNSTVVEADSLHYKSDLF---LNAAVLLALVLSQYGWWWADGQAF

5fvmA

0.08

1.00

0.71

MUSTER

LADLGKAHPQALVYPLTVAIKSDSVSRQRAALSIIDKMRMHSPKLVNQAELVSDELIRVAVLWHELWYEGLEDASRQFFGNTEKMFATLEPLHEMLKRISFQNSFGRDLNDAYEWVLNYKRTKDINNLNQAWDIYYNVFRRISRKLPQLQTLDLQHVSPKAAKDLELAVPGT

5cwqA2

0.07

0.05

0.70

0.67

dPPAS

----------------------------------SEEAERASEKAQRVLEEARKVSEEAREQGDDEVLALALIAIALAVLALAEVACCRGNKEEAERAYEDARRVEEEARKVKESAEEQGDSEVKRLAEEAEQLAREARRHVQECRGGWLEHHH------------------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-2.36

Estimated TM-score = 0.44±0.14

Estimated RMSD = 10.3±4.6Å

Download Model 2

C-score=-3.70

Download Model 3

C-score=-4.10

Download Model 4

C-score=-2.41

Download Model 5

C-score=-4.15

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	5cwdA	0.883	1.47	0.067	0.948
2	5cwbA	0.678	3.34	0.095	0.919
3	3l6aA	0.648	2.89	0.057	0.820
4	3juiA	0.644	3.47	0.045	0.884
5	1paqA	0.624	2.99	0.057	0.814
6	2zu6E1	0.624	2.76	0.066	0.785
7	3feyA1	0.621	3.85	0.038	0.878
8	4c0dA	0.619	4.55	0.072	0.948
9	3tj1A	0.611	4.01	0.025	0.884
10	5t8vA	0.609	3.93	0.055	0.861

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.12	6	1jkeA	ZN	Rep, Mult	56,60
2	0.06	3	3nk1X	GP7	Rep, Mult	23,39,84,85,88,105,116,117,120
3	0.06	3	2b2jA	XE	Rep, Mult	49,52,53
4	0.04	2	3g2wB	III	Rep, Mult	71,72,75,78,79,116,119,123
5	0.04	2	3pevB	IHP	Rep, Mult	63,67,104,107,108
6	0.04	2	4xgcC	III	Rep, Mult	54,55
7	0.02	1	3rovB	III	Rep, Mult	45,46
8	0.02	1	2p9xC	ZN	Rep, Mult	49,124
9	0.02	1	4ryoA	MPG	Rep, Mult	97,113,120
10	0.02	1	1h2u0	III	Rep, Mult	105,109,110,139
11	0.02	1	2wsc4	CLA	Rep, Mult	103,107
12	0.02	1	3cr3A	MG	Rep, Mult	21,33
13	0.02	1	2wse2	CLA	Rep, Mult	71,72

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	1bwkA	0.559	4.43	0.053	0.849	1.6.99.1	NA
2	0.060	1qoxM	0.564	4.57	0.083	0.872	3.2.1.21	104
3	0.060	1gonA	0.559	4.79	0.083	0.872	3.2.1.21	NA
4	0.060	3cmjA	0.560	4.84	0.070	0.878	3.2.1.21	NA
5	0.060	1hizA	0.549	4.47	0.027	0.831	3.2.1.8	140
6	0.060	2z1sA	0.566	4.47	0.058	0.855	3.2.1.21	130
7	0.060	1wcgA	0.571	4.52	0.073	0.855	3.2.1.147	NA
8	0.060	1us2A	0.552	4.47	0.034	0.837	3.2.1.8	NA
9	0.060	1gowA	0.562	4.71	0.069	0.889	3.2.1.23	NA
10	0.060	2pbgA	0.571	4.47	0.071	0.861	3.2.1.85	NA
11	0.060	1px8A	0.573	4.35	0.040	0.837	3.2.1.37	NA
12	0.060	1ujkB	0.482	4.13	0.102	0.727	3.4.23.46	63
13	0.060	2jieA	0.566	4.48	0.045	0.855	3.2.1.21	NA
14	0.060	1cbgA	0.572	4.43	0.066	0.843	3.2.1.21	NA
15	0.060	1dwaM	0.573	4.58	0.071	0.855	3.2.1.147	NA
16	0.060	1bgaA	0.573	4.53	0.083	0.866	3.2.1.21	NA
17	0.060	1vffA	0.548	4.64	0.073	0.849	3.2.1.21	NA
18	0.060	2bs9E	0.575	4.30	0.047	0.837	3.2.1.37	36
19	0.060	3hfwA	0.573	4.12	0.053	0.837	3.2.2.19	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.23	0.621	3.85	0.04	0.88	3feyA	GO:0000184 GO:0000339 GO:0000398 GO:0003723 GO:0005634 GO:0005654 GO:0005737 GO:0005739 GO:0005829 GO:0005845 GO:0005846 GO:0006366 GO:0006368 GO:0006369 GO:0006370 GO:0006397 GO:0006405 GO:0006406 GO:0006417 GO:0006446 GO:0006810 GO:0008334 GO:0008380 GO:0008543 GO:0010467 GO:0016070 GO:0030307 GO:0030529 GO:0031047 GO:0031124 GO:0031442 GO:0034518 GO:0042795 GO:0044822 GO:0045292 GO:0051028 GO:0051168 GO:0098789 GO:1900363
1	0.22	0.656	3.53	0.05	0.91	3juiA	GO:0001541 GO:0003743 GO:0005085 GO:0005634 GO:0005737 GO:0005829 GO:0005851 GO:0006412 GO:0006413 GO:0006417 GO:0007568 GO:0009408 GO:0009749 GO:0014002 GO:0014003 GO:0031369 GO:0032057 GO:0034976 GO:0035690 GO:0042552 GO:0043434 GO:0043547 GO:0045948 GO:0048708
2	0.19	0.650	2.95	0.06	0.84	1paqA	GO:0003743 GO:0005085 GO:0005851 GO:0006412 GO:0006413 GO:0006417 GO:0006446 GO:0009058 GO:0016779 GO:0032045 GO:0043547
3	0.17	0.648	2.89	0.06	0.82	3l6aA	GO:0003723 GO:0003743 GO:0005829 GO:0005913 GO:0006412 GO:0006413 GO:0006417 GO:0006446 GO:0007050 GO:0008135 GO:0008219 GO:0016020 GO:0016281 GO:0044822 GO:0098609 GO:0098641
4	0.12	0.645	2.77	0.04	0.80	2zu6B	GO:0003723 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0006915 GO:0007569 GO:0034393 GO:0043066 GO:0043508 GO:0045786 GO:0045892 GO:0051246 GO:1904761
5	0.11	0.564	3.83	0.06	0.81	1ug3A	GO:0000184 GO:0000289 GO:0001662 GO:0003723 GO:0003743 GO:0005737 GO:0005829 GO:0005913 GO:0006412 GO:0006413 GO:0006417 GO:0006446 GO:0008135 GO:0008190 GO:0016020 GO:0016032 GO:0016281 GO:0043488 GO:0044822 GO:0045666 GO:0098609 GO:0098641
6	0.08	0.562	2.81	0.05	0.70	2iosA	GO:0003723 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0006915 GO:0007569 GO:0034393 GO:0043066 GO:0043508 GO:0045892 GO:0051246 GO:1904761
7	0.07	0.620	3.55	0.05	0.85	2fulA	GO:0000166 GO:0001732 GO:0003743 GO:0005092 GO:0005096 GO:0005525 GO:0006412 GO:0006413 GO:0006446 GO:0022627 GO:0031369 GO:0033290 GO:0042256 GO:0043547 GO:0043614 GO:0045947 GO:0050790
8	0.07	0.600	4.00	0.03	0.87	2fulE	GO:0000166 GO:0001732 GO:0003743 GO:0005092 GO:0005096 GO:0005525 GO:0006412 GO:0006413 GO:0006446 GO:0022627 GO:0031369 GO:0033290 GO:0042256 GO:0043547 GO:0043614 GO:0045947 GO:0050790
9	0.07	0.604	3.79	0.06	0.87	2iu1A	GO:0000166 GO:0003743 GO:0003924 GO:0005525 GO:0005634 GO:0005737 GO:0005829 GO:0005886 GO:0005913 GO:0006412 GO:0006413 GO:0006446 GO:0008135 GO:0044822 GO:0098609 GO:0098641
10	0.07	0.534	5.02	0.07	0.85	4d0jA	GO:0000272 GO:0004553 GO:0005975 GO:0008152 GO:0008422 GO:0016787 GO:0016798 GO:0030245 GO:0102483
11	0.07	0.615	4.09	0.04	0.89	1h2uA	GO:0000184 GO:0000339 GO:0000398 GO:0003723 GO:0005634 GO:0005654 GO:0005737 GO:0005739 GO:0005829 GO:0005845 GO:0005846 GO:0006366 GO:0006368 GO:0006369 GO:0006370 GO:0006397 GO:0006405 GO:0006406 GO:0006417 GO:0006446 GO:0006810 GO:0008334 GO:0008380 GO:0008543 GO:0010467 GO:0016070 GO:0030307 GO:0030529 GO:0031047 GO:0031124 GO:0031442 GO:0034518 GO:0042795 GO:0044822 GO:0045292 GO:0051028 GO:0051168 GO:0098789 GO:1900363
12	0.06	0.469	4.70	0.06	0.72	1xdmB	GO:0001889 GO:0003824 GO:0004332 GO:0005634 GO:0005737 GO:0005764 GO:0005815 GO:0005829 GO:0005856 GO:0005886 GO:0006000 GO:0006094 GO:0006096 GO:0006116 GO:0008092 GO:0009743 GO:0009750 GO:0010043 GO:0014070 GO:0016829 GO:0030388 GO:0030867 GO:0030868 GO:0031210 GO:0031668 GO:0032781 GO:0032869 GO:0034451 GO:0042493 GO:0042594 GO:0042802 GO:0043200 GO:0043231 GO:0043434 GO:0046688 GO:0048471 GO:0051117 GO:0051384 GO:0051591 GO:0061609 GO:0061621 GO:0061624 GO:0070061 GO:0070062 GO:0070072 GO:0070741
13	0.06	0.476	4.27	0.06	0.72	2xn0A	GO:0003824 GO:0004553 GO:0004557 GO:0005975 GO:0008152 GO:0016787 GO:0016798 GO:0052692
14	0.06	0.405	4.52	0.08	0.62	1ujpA	GO:0000162 GO:0003824 GO:0004834 GO:0006568 GO:0008152 GO:0008652 GO:0009073 GO:0016829
15	0.06	0.382	5.39	0.07	0.66	3wpnA	GO:0000166 GO:0000922 GO:0003777 GO:0005524 GO:0005737 GO:0005819 GO:0005829 GO:0005856 GO:0005871 GO:0005874 GO:0005876 GO:0006890 GO:0007018 GO:0007049 GO:0007051 GO:0007052 GO:0007059 GO:0007067 GO:0007100 GO:0008017 GO:0008574 GO:0016020 GO:0019886 GO:0019901 GO:0032403 GO:0046602 GO:0051225 GO:0051301 GO:0090307
16	0.06	0.388	5.20	0.07	0.67	1v4vA	GO:0008761 GO:0016853
17	0.06	0.401	5.05	0.06	0.67	2mbgA	GO:0005096 GO:0005829 GO:0006810 GO:0006897 GO:0006935 GO:0007165 GO:0007264 GO:0016020 GO:0016887 GO:0017160 GO:0022857 GO:0043087 GO:0043492 GO:0043547 GO:0048365 GO:0051056 GO:0055085
18	0.06	0.397	4.80	0.01	0.64	2yxlA	GO:0003723 GO:0006364 GO:0008168 GO:0008757 GO:0032259

Consensus prediction of GO terms

Molecular Function	GO:0003743	GO:0016772	GO:0005085	GO:0044822	GO:0045296	GO:0098632
GO-Score	0.48	0.39	0.37	0.36	0.33	0.33
Biological Processes	GO:0031440	GO:0009452	GO:0071427	GO:0098787	GO:0045927	GO:0000377	GO:0006378	GO:0050685	GO:0006353	GO:0006354	GO:0051028	GO:0006405	GO:0001558	GO:0016458	GO:0009301	GO:0000956	GO:0007169	GO:0044344	GO:0008585	GO:0022602	GO:0045727	GO:0008366	GO:0009266	GO:0045947	GO:0021782	GO:0043558	GO:0009746	GO:1901652	GO:0042493	GO:0048709	GO:0009725	GO:0032055	GO:0048708	GO:0043547	GO:0022402	GO:0045786	GO:0007155
GO-Score	0.46	0.46	0.46	0.46	0.46	0.46	0.46	0.46	0.46	0.46	0.46	0.46	0.46	0.46	0.46	0.46	0.46	0.46	0.44	0.44	0.44	0.44	0.44	0.44	0.44	0.44	0.44	0.44	0.44	0.44	0.44	0.44	0.44	0.37	0.33	0.33	0.33
Cellular Component	GO:0005829	GO:0034518	GO:1990904	GO:0005851	GO:0005911	GO:0005912	GO:0005654
GO-Score	0.56	0.46	0.46	0.37	0.33	0.33	0.32

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv3669

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]