Threading Zmax Znorm MUSTER 5.09 0.88 dPPAS 6.40 0.69 wdPPAS 8.21 0.88 wMUSTER 6.03 1.04 wPPAS 8.62 1.23 dPPAS2 12.11 1.15 PPAS 6.74 0.96 Env-PPAS 5.94 0.74 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=19554) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.92 0.38+-0.13 10.7+-4.6 5630 0.057 model2 -3.29 2827 0.039 model3 -3.90 1842 0.021 model4 -4.24 1364 0.015 model5 -3.88 1300 0.022 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).