I-TASSER results

Input Sequence in FASTA format

>protein (217 residues)
MAIANPAEPGAAGRHHQPRGDRKPRAWRQCGPQNGPRRSQAITPEPGAAGRHHQPRGDRK
PRAWRQCGPQNGPRRSQAITPEPGAAGRHHQPRGDRKPRAWRQCGPQNGPRRSQAITPEP
GAAGRHHQPRGDRKPRAWRQCGPQNGPRRSQAITPEPGAAGRHHQPRGDRKPRAWRQCGP
QNGPRRSQAITPEPGAAGRHWLDQRPVVPDGVGKSDS

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 \| \| \| \| \| \| \| \| \| \| MAIANPAEPGAAGRHHQPRGDRKPRAWRQCGPQNGPRRSQAITPEPGAAGRHHQPRGDRKPRAWRQCGPQNGPRRSQAITPEPGAAGRHHQPRGDRKPRAWRQCGPQNGPRRSQAITPEPGAAGRHHQPRGDRKPRAWRQCGPQNGPRRSQAITPEPGAAGRHHQPRGDRKPRAWRQCGPQNGPRRSQAITPEPGAAGRHWLDQRPVVPDGVGKSDS
Prediction	CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
Conf.Score	9989999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999989999999
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 \| \| \| \| \| \| \| \| \| \| MAIANPAEPGAAGRHHQPRGDRKPRAWRQCGPQNGPRRSQAITPEPGAAGRHHQPRGDRKPRAWRQCGPQNGPRRSQAITPEPGAAGRHHQPRGDRKPRAWRQCGPQNGPRRSQAITPEPGAAGRHHQPRGDRKPRAWRQCGPQNGPRRSQAITPEPGAAGRHHQPRGDRKPRAWRQCGPQNGPRRSQAITPEPGAAGRHWLDQRPVVPDGVGKSDS
Prediction	7460644764461674537366346447446466355447446365156266465566456465475447624635734637614616646563762562474664763463664563752572564655774554664755574456347446466155266465646634635646647634636645637514634634776444376436688
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MAIANPAEPGAAGRHHQPRGDRKPRAWRQCGPQNGPRRSQAITPEPGAAGRHHQPRGDRKPRAWRQCGPQNGPRRSQAITPEPGAAGRHHQPRGDRKPRAWRQCGPQNGPRRSQAITPEPGAAGRHHQPRGDRKPRAWRQCGPQNGPRRSQAITPEPGAAGRHHQPRGDRKPRAWRQCGPQNGPRRSQAITPEPGAAGRHWLDQRPVVPDGVGKSDS

2i13A

0.19

0.13

0.69

2.21

MUSTER

-----FSRSDHLAEHQRTH---KPYKCPECGKSFSDKKDL----------RHQRTHTGEKPYKCPECGKSFS---------QRANLRAHQRTHTGEKPYACPECGKSFSQLAHLR---------AHQRTHTGEKPYKCPECGKSFSREDN---------LHTHQRTHTGEKPYKCPECGKSFSRRDALNV------HQRTH----------------

3boiA

0.12

0.05

0.37

5.20

dPPAS

-----------------------CKGADGAHGVNGCPGTAGAAGSVGGPGCDGGHGGNGGNGNPGCAGGVGGAGGASGGTGVGGRGGKGG-SGTPKGADGAPGAP----------------------------------------------------------------------------------------------------------------

3boiA

0.23

0.09

0.37

5.19

wdPPAS

-----------------------------CKGADGAHGVNGCPGTAGAAGSVGGPGCD-------------GGHGGNGGNGNPGCAGGVGGAGGASGGTGVGGRGGKGGSGTPKGADGAPGAP----------------------------------------------------------------------------------------------

2i13A

0.22

0.13

0.62

2.35

wMUSTER

--------------------------------------------RSDHLAEHQRTH---KPYKCPECGKSFS---------DKKDLTRHQRTHTGEKPYKCPECGKSFSQRANL----------AHQRTHTGEKPYACPECGKSFSQLAH---------LRAHQRTHTGEKPYKCPECGKSFSREDN--------THQRTHTGEKPYKCPECGKSFS

3jacA1

0.14

0.13

0.99

3.15

wPPAS

---GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG

3boiA

0.12

0.05

0.37

6.96

dPPAS2

-----------------------CKGADGAHGVNGCPGTAGAAGSVGGPGCDGGHGGNGGNGNPGCAGGVGGAGGASGGTGVGGRGGKGG-SGTPKGADGAPGAP----------------------------------------------------------------------------------------------------------------

3jacA1

0.14

0.13

0.98

3.41

PPAS

---GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-GGGGGGGGGGGGGGGGGGGG-GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG

3jacA1

0.13

1.00

1.71

Env-PPAS

GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG

1tf6D

0.13

0.10

0.72

1.95

MUSTER

------------------PVVYKRYICSFCGAAYNKNWKLQA---------HLCKHTGEKPFPCKECEKGFT---------SLHHLTRHSLTHTGEKNFTCDGCDLRFTTKANMK---------KHFNRFHNIKICHFENCGKAFKKHNQ---------LKVHQFSHTQQLPYECPGCDKRFSLPSRL-------RHEKVHAGYPCKKDSFVGKTWT

3bogA

0.20

0.07

0.37

4.57

dPPAS

-----------------------------------------CKGADGAHG-VGCPGTAGAAGSVGGPG-CDGGHGGNGGNGNPGCAGGVGGAGGASGGTGVGGRGGKGGSGTPKGADGAPGAP----------------------------------------------------------------------------------------------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-3.72

Estimated TM-score = 0.31±0.10

Estimated RMSD = 14.5±3.7Å

Download Model 2

C-score=-3.87

Download Model 3

C-score=-3.99

Download Model 4

C-score=-4.09

Download Model 5

C-score=-4.10

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	2i13A	0.578	3.10	0.159	0.687
2	3ugmA	0.462	5.79	0.058	0.788
3	4yibA	0.442	5.76	0.041	0.770
4	5egbA	0.441	2.39	0.189	0.511
5	4f5cA	0.440	5.68	0.047	0.751
6	5apbA	0.435	5.62	0.010	0.747
7	5a22A	0.435	6.13	0.040	0.806
8	4n5cA	0.434	5.69	0.026	0.751
9	3sqgA1	0.434	5.85	0.051	0.760
10	1ry2A	0.433	6.11	0.005	0.797

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.11	6	1a1lA	NUC	Rep, Mult	60,69,71,82,85,88,89,92,106,108,109,110,113,126,129,147,150,162
2	0.10	5	2i13A	NUC	Rep, Mult	33,47,50,51,55,69,71,82,85,89,92,110,113,126,129,145,147,150,163,166,182,184
3	0.06	3	1p47A	NUC	Rep, Mult	60,70,82,85,88,89,106,108,109,110,113,126,129,143,145,147,150,162,163,166
4	0.04	2	1meyF	QNA	Rep, Mult	32,34,35,36,39,51,52,55,85,88,89,92,106,110,113,125,126,129
5	0.04	2	1aklA	CA	Rep, Mult	159,160,161,163,181,182
6	0.02	1	1c8fA	CA	Rep, Mult	88,91
7	0.02	1	1c9uA	CA	Rep, Mult	74,87,88,191
8	0.02	1	1cq1A	CA	Rep, Mult	55,68,69
9	0.02	1	1c9uB	CA	Rep, Mult	109,110,200
10	0.02	1	3fbyA	CA	Rep, Mult	72,74,82,84,87
11	0.02	1	1meyC	UUU	Rep, Mult	84,87,99,111,112,125
12	0.02	1	1cq1B	CA	Rep, Mult	68,69
13	0.02	1	2xgfC	CO3	Rep, Mult	130,131,132

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	1p8jA	0.405	5.78	0.064	0.710	3.4.21.75	NA
2	0.060	2qr5A	0.434	5.27	0.036	0.714	3.4.19.1	NA
3	0.060	1cjyA	0.413	6.26	0.031	0.783	3.1.1.4,3.1.1.5	NA
4	0.060	1t3tA	0.413	6.52	0.068	0.820	6.3.5.3	198
5	0.060	4kbpA	0.404	6.16	0.034	0.737	3.1.3.2	NA
6	0.060	1e1yA	0.422	6.11	0.039	0.774	2.4.1.1	NA
7	0.060	2zuwC	0.403	5.89	0.041	0.705	2.4.1.211	93,96
8	0.060	3fu7B	0.412	6.04	0.025	0.751	1.10.3.2	158,191
9	0.060	1kb0A	0.414	5.98	0.046	0.756	1.1.99.-	NA
10	0.060	3ig5A	0.405	5.65	0.021	0.696	6.3.2.2	NA
11	0.060	1ej6A	0.410	5.78	0.027	0.696	2.7.7.50	85
12	0.060	3ej6D	0.373	5.81	0.070	0.677	1.11.1.6	83,87
13	0.060	2qb7A	0.410	5.48	0.018	0.701	3.6.1.11	NA
14	0.060	1yiqA	0.423	5.75	0.036	0.737	1.1.99.-	NA
15	0.060	1z1wA	0.405	5.68	0.042	0.705	3.4.11.-	NA
16	0.060	2qt6A	0.407	6.08	0.035	0.747	1.10.3.2	NA
17	0.060	1ox4B	0.412	5.78	0.038	0.710	4.1.3.-	83
18	0.060	1kbpA	0.406	6.11	0.040	0.747	3.1.3.2	NA
19	0.060	1gw0A	0.409	6.03	0.030	0.742	1.10.3.2	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.23	0.526	3.15	0.17	0.64	2i13B	GO:0000977 GO:0003676 GO:0003677 GO:0003700 GO:0005634 GO:0006351 GO:0006355 GO:0007275 GO:0007283 GO:0030154 GO:0046872
1	0.14	0.578	3.10	0.16	0.69	2i13A	GO:0000977 GO:0003676 GO:0003677 GO:0003700 GO:0005634 GO:0006351 GO:0006355 GO:0007275 GO:0007283 GO:0030154 GO:0046872
2	0.07	0.360	1.89	0.19	0.39	1p47A	GO:0000122 GO:0000976 GO:0000977 GO:0000982 GO:0001077 GO:0003676 GO:0003677 GO:0003700 GO:0005634 GO:0005654 GO:0005737 GO:0006351 GO:0006355 GO:0006366 GO:0009749 GO:0030217 GO:0030509 GO:0032868 GO:0033233 GO:0035035 GO:0035914 GO:0042981 GO:0043565 GO:0044212 GO:0045893 GO:0045944 GO:0046872 GO:0061418 GO:0070498 GO:0071310 GO:0071480 GO:0071504 GO:0071506 GO:0072110 GO:0072303 GO:0090090
3	0.07	0.441	2.39	0.19	0.51	5egbA	GO:0003676 GO:0005622 GO:0005634 GO:0005654 GO:0005694 GO:0006311 GO:0006351 GO:0006355 GO:0008168 GO:0010845 GO:0016568 GO:0016740 GO:0018024 GO:0032259 GO:0034968 GO:0046872 GO:0051321
4	0.06	0.422	3.02	0.13	0.52	2gliA	GO:0000977 GO:0000978 GO:0001649 GO:0003676 GO:0003677 GO:0003682 GO:0003705 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0005929 GO:0005930 GO:0006351 GO:0006355 GO:0007224 GO:0007275 GO:0007283 GO:0007418 GO:0008017 GO:0008284 GO:0008589 GO:0009611 GO:0009913 GO:0009953 GO:0009954 GO:0021696 GO:0021938 GO:0021983 GO:0030154 GO:0030324 GO:0030335 GO:0043231 GO:0043565 GO:0044212 GO:0045667 GO:0045740 GO:0045880 GO:0045893 GO:0045944 GO:0046872 GO:0048546 GO:0060032 GO:0060070 GO:0072372 GO:0090090 GO:0097421 GO:0097542 GO:0097546 GO:2000345
5	0.06	0.370	2.82	0.12	0.44	2jp9A	GO:0000122 GO:0001077 GO:0001570 GO:0001657 GO:0001658 GO:0001822 GO:0003156 GO:0003676 GO:0003677 GO:0003700 GO:0003723 GO:0005634 GO:0005654 GO:0005730 GO:0005737 GO:0006351 GO:0006355 GO:0006357 GO:0006366 GO:0007281 GO:0007356 GO:0007507 GO:0007530 GO:0008270 GO:0008285 GO:0008380 GO:0008406 GO:0008584 GO:0009888 GO:0016607 GO:0017148 GO:0030308 GO:0030325 GO:0030539 GO:0030855 GO:0032835 GO:0032836 GO:0035802 GO:0043010 GO:0043065 GO:0043066 GO:0043565 GO:0044212 GO:0045892 GO:0045893 GO:0045944 GO:0046872 GO:0060231 GO:0060421 GO:0060539 GO:0060923 GO:0061032 GO:0070742 GO:0071320 GO:0071371 GO:0072075 GO:0072112 GO:0072166 GO:0072207 GO:0072284 GO:0072302 GO:2000020 GO:2000195 GO:2001076
6	0.06	0.376	5.74	0.03	0.65	4g9iA	GO:0003725 GO:0008270 GO:0016743 GO:0046872 GO:0046944
7	0.06	0.356	2.22	0.17	0.40	1g2dC	GO:0000122 GO:0000976 GO:0000977 GO:0000982 GO:0001077 GO:0003676 GO:0003677 GO:0003700 GO:0005634 GO:0005654 GO:0005737 GO:0006351 GO:0006355 GO:0006366 GO:0009749 GO:0030217 GO:0030509 GO:0032868 GO:0033233 GO:0035035 GO:0035914 GO:0042981 GO:0043565 GO:0044212 GO:0045893 GO:0045944 GO:0046872 GO:0061418 GO:0070498 GO:0071310 GO:0071480 GO:0071504 GO:0071506 GO:0072110 GO:0072303 GO:0090090
8	0.06	0.353	2.94	0.07	0.41	1tf6D	GO:0003676 GO:0003677 GO:0003723 GO:0005634 GO:0006351 GO:0006355 GO:0046872
9	0.06	0.355	1.90	0.19	0.39	1meyF
10	0.06	0.410	2.88	0.14	0.49	1ubdC	GO:0000122 GO:0000400 GO:0000724 GO:0001078 GO:0001158 GO:0003676 GO:0003677 GO:0003700 GO:0003713 GO:0003714 GO:0003723 GO:0005634 GO:0006281 GO:0006310 GO:0006351 GO:0006355 GO:0006357 GO:0006974 GO:0007283 GO:0008270 GO:0010225 GO:0010629 GO:0016363 GO:0030154 GO:0031011 GO:0034644 GO:0044212 GO:0046332 GO:0046872
11	0.06	0.337	2.04	0.16	0.38	2kmkA	GO:0000122 GO:0001078 GO:0003676 GO:0003677 GO:0005634 GO:0006351 GO:0006355 GO:0010956 GO:0010977 GO:0016363 GO:0016604 GO:0017053 GO:0030097 GO:0030099 GO:0034121 GO:0044212 GO:0045892 GO:0046872 GO:0050767 GO:0051569 GO:0070105 GO:0071222
12	0.06	0.351	6.52	0.05	0.70	3tsqA	GO:0003725 GO:0008270 GO:0016743 GO:0046872 GO:0046944
13	0.06	0.350	3.59	0.09	0.44	2lt7A	GO:0003676 GO:0003677 GO:0005634 GO:0005654 GO:0005730 GO:0005737 GO:0005886 GO:0006351 GO:0006355 GO:0008327 GO:0016055 GO:0035556 GO:0043565 GO:0045892 GO:0046872
14	0.06	0.248	3.69	0.11	0.32	1x6hA	GO:0000122 GO:0000775 GO:0000793 GO:0000978 GO:0001078 GO:0001228 GO:0003676 GO:0003677 GO:0003682 GO:0003700 GO:0003714 GO:0005634 GO:0005654 GO:0005694 GO:0005730 GO:0006306 GO:0006349 GO:0006351 GO:0006355 GO:0006366 GO:0007059 GO:0008270 GO:0010216 GO:0010628 GO:0010629 GO:0016568 GO:0016584 GO:0031060 GO:0035065 GO:0040029 GO:0040030 GO:0043035 GO:0043565 GO:0044212 GO:0045892 GO:0045893 GO:0045944 GO:0046872 GO:0070602
15	0.06	0.233	2.20	0.14	0.26	1f2iG	GO:0000122 GO:0000976 GO:0000977 GO:0000982 GO:0001077 GO:0003676 GO:0003677 GO:0003700 GO:0005634 GO:0005654 GO:0005737 GO:0006351 GO:0006355 GO:0006366 GO:0009749 GO:0030217 GO:0030509 GO:0032868 GO:0033233 GO:0035035 GO:0035914 GO:0042981 GO:0043565 GO:0044212 GO:0045893 GO:0045944 GO:0046872 GO:0061418 GO:0070498 GO:0071310 GO:0071480 GO:0071504 GO:0071506 GO:0072110 GO:0072303 GO:0090090
16	0.06	0.213	4.78	0.04	0.33	2dlqA	GO:0003676 GO:0003677 GO:0005634 GO:0005654 GO:0005737 GO:0006351 GO:0006355 GO:0046872
17	0.06	0.246	2.42	0.18	0.28	4m9vC	GO:0000122 GO:0003676 GO:0003677 GO:0005622 GO:0005634 GO:0005720 GO:0006349 GO:0006351 GO:0006355 GO:0007275 GO:0043045 GO:0046872
18	0.06	0.234	2.13	0.14	0.26	1llmC	GO:0000122 GO:0000790 GO:0000976 GO:0000977 GO:0000978 GO:0000981 GO:0000982 GO:0001077 GO:0001080 GO:0001084 GO:0001135 GO:0001190 GO:0001191 GO:0003676 GO:0003677 GO:0003682 GO:0003700 GO:0005634 GO:0005654 GO:0005667 GO:0005737 GO:0006351 GO:0006355 GO:0006366 GO:0008652 GO:0009749 GO:0010691 GO:0030217 GO:0030509 GO:0032868 GO:0033233 GO:0035035 GO:0035914 GO:0042802 GO:0042981 GO:0043565 GO:0044212 GO:0045893 GO:0045899 GO:0045944 GO:0046872 GO:0060261 GO:0061418 GO:0070498 GO:0071310 GO:0071480 GO:0071504 GO:0071506 GO:0072110 GO:0072303 GO:0090090 GO:1903833

Consensus prediction of GO terms

Molecular Function	GO:0046872	GO:0000977	GO:0003700
GO-Score	0.47	0.42	0.39
Biological Processes	GO:0006355	GO:0030154	GO:0007275	GO:0007283
GO-Score	0.47	0.38	0.38	0.38
Cellular Component	GO:0031981
GO-Score	0.40

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv3611

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]