I-TASSER results

I-TASSER results for job id Rv3603c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (303 residues)
MERFDGLRPARLKVGIISAGRVGTALGVALQRADHVVVACSAISHASRRRAQRRLPDTPV
LPPLDVAASAELLLLAVTDSELAGLVSGLAATSAVRPQTIVAHTSGANGIGILAPLAQQG
CIPLAIHPAMTFTGSDEDISRLPDTCFGITAADDVGYAIGQSLVLEMGGEPFCVREDARI
LYHAALAHASNHIVTVLADALEALRAALSGGELLGQQTVDDQPGGIVERIVGPLARAALE
NTLQRGQAALTGPVARGDAAAVADHLAALADVDAALAQAYRINALRTAQRAHAPADVVEV
LTA

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| MERFDGLRPARLKVGIISAGRVGTALGVALQRADHVVVACSAISHASRRRAQRRLPDTPVLPPLDVAASAELLLLAVTDSELAGLVSGLAATSAVRPQTIVAHTSGANGIGILAPLAQQGCIPLAIHPAMTFTGSDEDISRLPDTCFGITAADDVGYAIGQSLVLEMGGEPFCVREDARILYHAALAHASNHIVTVLADALEALRAALSGGELLGQQTVDDQPGGIVERIVGPLARAALENTLQRGQAALTGPVARGDAAAVADHLAALADVDAALAQAYRINALRTAQRAHAPADVVEVLTA
Prediction	CCCCCCCCCCCCEEEEHCCCHHHHHHHHHHHHHCCEEEEEHCCCHHHHHHHHHHCCCEEHCCHHHHHHCCCEEEEHCCHHHHHHHHHHHHHCCCCCCCEEEEHCCCCCCHHHHHHHHHHCCEEEEEHCCCCCCCCHHHHHHCCCCEEEEHCCCHHHHHHHHHHHHHHCCCEEEHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHC
Conf.Score	998888888886899987987899999999998996999968999999999998598885999999865989999768789999999998667788996999879998689999999989968998467778887678887589889997799999999999999999958996877879999999999999999999999999998887654555554566555699999999999999999858556866654485999999999999758899999999999999997888668998869
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| MERFDGLRPARLKVGIISAGRVGTALGVALQRADHVVVACSAISHASRRRAQRRLPDTPVLPPLDVAASAELLLLAVTDSELAGLVSGLAATSAVRPQTIVAHTSGANGIGILAPLAQQGCIPLAIHPAMTFTGSDEDISRLPDTCFGITAADDVGYAIGQSLVLEMGGEPFCVREDARILYHAALAHASNHIVTVLADALEALRAALSGGELLGQQTVDDQPGGIVERIVGPLARAALENTLQRGQAALTGPVARGDAAAVADHLAALADVDAALAQAYRINALRTAQRAHAPADVVEVLTA
Prediction	756376353240100000023002000310262403000012134500440163044231230440054020000003262034005402735414420000000222324004403733020000000100234441054044000000033640251033005403441240367313200000000010110001101300330234443244443442434213400230043005303732450010103231260044015204732540250032004300632446531340168
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCCCCCEEEEHCCCHHHHHHHHHHHHHCCEEEEEHCCCHHHHHHHHHHCCCEEHCCHHHHHHCCCEEEEHCCHHHHHHHHHHHHHCCCCCCCEEEEHCCCCCCHHHHHHHHHHCCEEEEEHCCCCCCCCHHHHHHCCCCEEEEHCCCHHHHHHHHHHHHHHCCCEEEHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHC
MERFDGLRPARLKVGIISAGRVGTALGVALQRADHVVVACSAISHASRRRAQRRLPDTPVLPPLDVAASAELLLLAVTDSELAGLVSGLAATSAVRPQTIVAHTSGANGIGILAPLAQQGCIPLAIHPAMTFTGSDEDISRLPDTCFGITAADDVGYAIGQSLVLEMGGEPFCVREDARILYHAALAHASNHIVTVLADALEALRAALSGGELLGQQTVDDQPGGIVERIVGPLARAALENTLQRGQAALTGPVARGDAAAVADHLAALADVDAALAQAYRINALRTAQRAHAPADVVEVLTA

3d1lB

0.19

0.16

0.82

1.69

MUSTER

IED--------TPIVLIGAGNLATNLAKALYRKGFRIVQVYSRTEESARELAQKVEAEYTTDLAEVNPYAKLYIVSLKDSAFAELLQGIVEG---KREEALVHTAGSIPNVWEGHV----PHYGVFYPQTFSKQREVD---FKEIPFFIEASSTEDAAFLKAIASTLSNRVYDADSEQRKSLHLAAVFTCNFTNHYALAAELLKKY--LPFD------------------VLPLIDETARKVHELEPTAQTGPAIRYDENVIGNHLRLADDPA---QRLYELLSRSIHER-------------

3d1lB

0.19

0.16

0.83

1.78

dPPAS

-------SIEDTPIVLIGAGNLATNLAKALYRKGFRIVQVYSRTEESARELAQKVEAEYTTDLAEVNPYAKLYIVSLKDSAFAELLQGIVE---GKREEALVHTAGSIPNVWEGHV----PHYGVFYPQTFSKQREVD---FKEIPFFIEASSTEDAAFLKAIASTLSNRVYDADSEQRKSLHLAAVFTCNFTNHYALAAELLKKYNLPFD-------------------VLPLIDETARKVHELEPTAQTGPAIRYDENVIGNHLRLADDPA---QRLYELLSRSIHER-------------

3d1lB

0.19

0.16

0.83

2.27

wdPPAS

-------SIEDTPIVLIGAGNLATNLAKALYRKGFRIVQVYSRTEESARELAQKVEAEYTTDLAEVNPYAKLYIVSLKDSAFAELLQGIVEG---KREEALVHTAGSIPNVWEGHVPH----YGVFYPQTFSKQREVD---FKEIPFFIEASSTEDAAFLKAIASTLSNRVYDADSEQRKSLHLAAVFTCNFTNHYALAAELLKKY--LPFD------------------VLPLIDETARKVHELEPTAQTGPAIRYDENVIGNHLRLADDPA---QRLYELLSRSIHER-------------

3d1lB

0.19

0.16

0.82

2.10

wMUSTER

IED--------TPIVLIGAGNLATNLAKALYRKGFRIVQVYSRTEESARELAQKVEAEYTTDLAEVNPYAKLYIVSLKDSAFAELLQGIVEG---KREEALVHTAGSIPNVWEGHVPHY----GVFYPQTFSKQREVD---FKEIPFFIEASSTEDAAFLKAIASTLSNRVYDADSEQRKSLHLAAVFTCNFTNHYALAAELLKKY--LPFD------------------VLPLIDETARKVHELEPTAQTGPAIRYDENVIGNHLRLADDPA---QRLYELLSRSIHER-------------

3d1lB

0.19

0.16

0.82

2.93

wPPAS

IED--------TPIVLIGAGNLATNLAKALYRKGFRIVQVYSRTEESARELAQKVEAEYTTDLAEVNPYAKLYIVSLKDSAFAELLQGIVE---GKREEALVHTAGSIPNVWEGHVPHY----GVFYPQTFSKQREVD---FKEIPFFIEASSTEDAAFLKAIASTLSNRVYDADSEQRKSLHLAAVFTCNFTNHYALAAELLKKY--LPFD------------------VLPLIDETARKVHELEPTAQTGPAIRYDENVIGNHLRLADDPA---QRLYELLSRSIHER-------------

3d1lB

0.19

0.16

0.83

3.18

dPPAS2

-------SIEDTPIVLIGAGNLATNLAKALYRKGFRIVQVYSRTEESARELAQKVEAEYTTDLAEVNPYAKLYIVSLKDSAFAELLQGIVE---GKREEALVHTAGSIPNVWEGHV----PHYGVFYPQTFSKQREVD---FKEIPFFIEASSTEDAAFLKAIASTLSNRVYDADSEQRKSLHLAAVFTCNFTNHYALAAELLKKYNLPFD-------------------VLPLIDETARKVHELEPTAQTGPAIRYDENVIGNHLRLADDPA---QRLYELLSRSIHER-------------

3d1lB

0.19

0.16

0.83

2.73

PPAS

-------SIEDTPIVLIGAGNLATNLAKALYRKGFRIVQVYSRTEESARELAQKVEAEYTTDLAEVNPYAKLYIVSLKDSAFAELLQGIVE---GKREEALVHTAGSIPNVWEGHVPHY----GVFYPQTFSKQREVD---FKEIPFFIEASSTEDAAFLKAIASTLSNRVYDADSEQRKSLHLAAVFTCNFTNHYALAAELLKKY--LPFD------------------VLPLIDETARKVHELEPTAQTGPAIRYDENVIGNHLRLADDPA---QRLYELLSRSIHER-------------

2i76A

0.18

0.15

0.81

3.21

Env-PPAS

-----------V-LNFVGTGTLTRFFLECL-----KIGYILSRSIDRARNLAEVYG----GKAATLEKHPEVVFVIVPDRYIKTVANHLN-----LGDAVLVHCSGFLSSEIFK-----KSGRASIHPNFSFLEKALE---KDQIVFGLEG-DERGLPIVKKIAEEISGKYFVIPSEKKKAYHLAAVIASNFPVALAYLSKRIYTLLGLDE----------------PELLIHTLKGVADNIKKRVECSLTGPVKRGDWQVVEEERREYEKIFGN-TVLYDEIVKLLREVAESERR-------

2i76A

0.18

0.15

0.81

1.64

MUSTER

------------VLNFVGTGTLTRFFLECL-----KIGYILSRSIDRARNLAEVYGG----KAATLEKHPEVVFVIVPDRYIKTVANHLN-----LGDAVLVHCSGFLSSEIFK-----KSGRASIHPNFSFLEKALE---KDQIVFGLEG-DERGLPIVKKIAEEISGKYFVIPSEKKKAYHLAAVIASNFPVALAYLSKRIYTLLGLDE----------------PELLIHTLKGVADNIKKRVECSLTGPVKRGDWQVVEEERREYEKIFGN-TVLYDEIVKLLREVAESERR-------

2i76A

0.18

0.15

0.81

1.68

dPPAS

------------VLNFVGTGTLTRFFLECL-----KIGYILSRSIDRARNLAEVYGGKAATL----EKHPEVVFVIVPDRYIKTVANHLN-----LGDAVLVHCSGFLSSEIFK-----KSGRASIHPNFSFLEKALE---KDQIVFGLEG-DERGLPIVKKIAEEISGKYFVIPSEKKKAYHLAAVIASNFPVALAYLSKRIYTLLGLDE----------------PELLIHTLKGVADNIKKRVECSLTGPVKRGDWQVVEEERREYEKIFGN-TVLYDEIVKLLREVAESERR-------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-0.35

Estimated TM-score = 0.67±0.13

Estimated RMSD = 7.0±4.1Å

Download Model 2

C-score=-0.69

Download Model 3

C-score=-1.73

Download Model 4

C-score=-2.05

Download Model 5

C-score=-3.02

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	3d1lB	0.796	1.35	0.199	0.828
2	3l6dB	0.656	4.35	0.109	0.871
3	4d3sA	0.650	4.27	0.111	0.865
4	4oqzA	0.649	4.13	0.116	0.848
5	1yrlA	0.647	4.75	0.105	0.875
6	4xdzA	0.642	4.26	0.110	0.832
7	3fr8B	0.639	4.94	0.098	0.894
8	4xdyA	0.637	4.16	0.087	0.819
9	3qhaA	0.637	3.88	0.143	0.828
10	4tskA	0.636	4.17	0.087	0.819

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.36	29	3plrA	NAI	Rep, Mult	18,20,21,22,42,43,44,47,76,77,78,105,106,128,130,132,183
2	0.06	5	2amfA	PRO	Rep, Mult	22,104,127,128,130
3	0.03	2	3d1lB	MPR	Rep, Mult	130,183,186,190,191
4	0.03	2	3d1lB	MPR	Rep, Mult	234,251,252
5	0.02	2	3fwnB	ATR	Rep, Mult	42,43,44,47,77,78,81,84
6	0.01	1	2gr9B	UUU	Rep, Mult	143,144,165,166,167,168
7	0.01	1	2i76A	NDP	Rep, Mult	251,256
8	0.01	1	1muuC	SUC	Rep, Mult	13,68,69,70,71,98,99
9	0.01	1	3d1lA	MPR	Rep, Mult	190,191

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.212	3gt0A	0.513	3.38	0.126	0.621	1.5.1.2	25,107,128,131
2	0.066	3dojA	0.555	4.14	0.073	0.713	1.1.1.79	NA
3	0.066	1np3A	0.600	4.76	0.110	0.812	1.1.1.86	NA
4	0.060	2o3jA	0.568	4.51	0.113	0.736	1.1.1.22	NA
5	0.060	3itkC	0.567	4.25	0.095	0.729	1.1.1.22	105
6	0.060	1mfzA	0.648	4.53	0.089	0.884	1.1.1.132	NA
7	0.060	3gg2A	0.590	3.53	0.109	0.726	1.1.1.22	115
8	0.060	1dliA	0.541	4.38	0.086	0.696	1.1.1.22	NA
9	0.060	2h78A	0.541	4.17	0.120	0.677	1.1.1.31	NA
10	0.060	1x0xA	0.555	4.33	0.099	0.736	1.1.1.8	NA
11	0.060	3ckyC	0.530	4.22	0.098	0.660	1.1.1.291	23,145,180,186
12	0.060	2jkvA	0.630	4.26	0.082	0.848	1.1.1.44	NA
13	0.060	1txgA	0.550	4.57	0.118	0.739	1.1.1.94	NA
14	0.060	1yj8A	0.546	4.63	0.088	0.739	1.1.1.8	NA
15	0.060	1pgjA	0.626	4.57	0.079	0.861	1.1.1.44	NA
16	0.060	2amfE	0.617	3.69	0.141	0.769	1.5.1.2	25,107,130,172,193
17	0.060	2i9pB	0.526	4.15	0.109	0.657	1.1.1.31	145,173
18	0.060	2f1kA	0.551	4.10	0.140	0.677	1.3.1.43	NA
19	0.060	1txgB	0.548	4.61	0.124	0.736	1.1.1.94	109
20	0.060	3h2zA	0.572	4.67	0.112	0.785	1.1.1.17	76,109,188
21	0.060	2izzB	0.621	3.82	0.116	0.792	1.5.1.2	NA
22	0.060	3khuB	0.569	4.30	0.099	0.733	1.1.1.22	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.51	0.811	1.38	0.20	0.84	3d1lB	GO:0055114
1	0.25	0.625	3.65	0.13	0.78	2i76A	GO:0000166 GO:0055114
2	0.24	0.662	4.06	0.10	0.86	4oqyB	GO:0000166 GO:0004616 GO:0016491 GO:0055114
3	0.20	0.638	4.53	0.08	0.88	3zgyD	GO:0000166 GO:0004616 GO:0016020 GO:0016021 GO:0016491 GO:0055114
4	0.20	0.667	4.31	0.10	0.88	3l6dB	GO:0004616 GO:0016491 GO:0055114
5	0.19	0.649	4.13	0.12	0.85	4oqzA	GO:0004616 GO:0016491 GO:0055114
6	0.18	0.597	4.81	0.11	0.84	5a9rA	GO:0004616 GO:0016491 GO:0055114
7	0.18	0.585	4.48	0.11	0.76	3gggD	GO:0000166 GO:0004665 GO:0006571 GO:0008977 GO:0055114 GO:0070403
8	0.15	0.605	4.79	0.09	0.85	3fwnA	GO:0004616 GO:0005829 GO:0006098 GO:0016491 GO:0019521 GO:0042802 GO:0042803 GO:0055114
9	0.07	0.551	4.20	0.10	0.70	4dllA	GO:0004616 GO:0008679 GO:0016491 GO:0051287 GO:0055114
10	0.07	0.598	4.82	0.08	0.83	2w90B
11	0.07	0.538	4.10	0.12	0.67	3obbA	GO:0000166 GO:0004616 GO:0006565 GO:0008442 GO:0009083 GO:0016491 GO:0016616 GO:0051287 GO:0051289 GO:0055114
12	0.07	0.561	4.00	0.10	0.71	3w6zA	GO:0000166 GO:0004616 GO:0016491 GO:0051287 GO:0055114
13	0.07	0.551	4.21	0.11	0.71	1vpdA	GO:0004616 GO:0008679 GO:0016491 GO:0046392 GO:0046487 GO:0051287 GO:0055114
14	0.07	0.554	3.99	0.09	0.71	2uyyA	GO:0003677 GO:0004616 GO:0005634 GO:0005654 GO:0005737 GO:0005794 GO:0016491 GO:0035064 GO:0051287 GO:0055114
15	0.07	0.555	4.14	0.07	0.71	3dojA	GO:0003858 GO:0004616 GO:0005737 GO:0005829 GO:0006979 GO:0016491 GO:0016616 GO:0030267 GO:0051287 GO:0055114
16	0.07	0.544	3.90	0.09	0.69	3pduA	GO:0000166 GO:0004616 GO:0016491 GO:0051287 GO:0055114
17	0.07	0.551	4.19	0.09	0.69	4gbjC	GO:0004616 GO:0016491 GO:0051287 GO:0055114
18	0.07	0.553	3.97	0.11	0.71	3k96A	GO:0004367 GO:0005737 GO:0005975 GO:0006072 GO:0006629 GO:0006650 GO:0008654 GO:0009331 GO:0016491 GO:0016616 GO:0036439 GO:0046167 GO:0046168 GO:0047952 GO:0051287 GO:0055114

Consensus prediction of GO terms

Molecular Function	GO:0000166	GO:0004616
GO-Score	0.55	0.52
Biological Processes	GO:0055114
GO-Score	0.82
Cellular Component	GO:0031224
GO-Score	0.33

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.