I-TASSER results

I-TASSER results for job id Rv3577

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (288 residues)
MPTARSDAPLSVTWMGVATLLVDDGSSALMTDGYFSRPGLARVAAGKVSPSAERVDGCLA
RANVSRLTAVIPVHTHIDHAMDSALVADRTGAQLVGGESAANVGRGYGLPEESLVVAVPG
EPIQLGAFDVTLVESHHCPPDRFPGVISAPLTPPVKASAYRCGEAWSTLVHHRPSGRRLL
IQDSAGFVSGALAGYRADAAYLSVGQLGLQPPSYLLEYWTETVRTVGVRRVILIHWDDFF
RPLSKPLRALPYAADDLDLSIRILDELAAQDGVALQMPTVWRREDPWM

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 280 \| \| \| \| \| \| \| \| \| \| \| \| \| \| MPTARSDAPLSVTWMGVATLLVDDGSSALMTDGYFSRPGLARVAAGKVSPSAERVDGCLARANVSRLTAVIPVHTHIDHAMDSALVADRTGAQLVGGESAANVGRGYGLPEESLVVAVPGEPIQLGAFDVTLVESHHCPPDRFPGVISAPLTPPVKASAYRCGEAWSTLVHHRPSGRRLLIQDSAGFVSGALAGYRADAAYLSVGQLGLQPPSYLLEYWTETVRTVGVRRVILIHWDDFFRPLSKPLRALPYAADDLDLSIRILDELAAQDGVALQMPTVWRREDPWM
Prediction	CCCCCCCCCEEEEEEHCCEEEEEHCCEEEEHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCEEEHCCCCCCCCCCHHHHHHHCCCEEEHCHHHHHHHHHHCCCCCCEEEHCCCEEEEHCCEEEEEEHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEHCCCCCEEEEHCCCCCCCHHHCCCCCCEEEHCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEHCCCCCCCCCCCCCHHHHHHHHHHHCCCEEHCCCCCCCCCCCCCCCCCCCCCCCCC
Conf.Score	999999997799999555999999998999889999998876667778888767787777676899989998899988888789999856998997857999999989985556887798899998899999985578888888876667777766667667765789999958996999967999986565687888788777777788877999999999999899989986889887876577899999999879974554555555676555788876677899
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 280 \| \| \| \| \| \| \| \| \| \| \| \| \| \| MPTARSDAPLSVTWMGVATLLVDDGSSALMTDGYFSRPGLARVAAGKVSPSAERVDGCLARANVSRLTAVIPVHTHIDHAMDSALVADRTGAQLVGGESAANVGRGYGLPEESLVVAVPGEPIQLGAFDVTLVESHHCPPDRFPGVISAPLTPPVKASAYRCGEAWSTLVHHRPSGRRLLIQDSAGFVSGALAGYRADAAYLSVGQLGLQPPSYLLEYWTETVRTVGVRRVILIHWDDFFRPLSKPLRALPYAADDLDLSIRILDELAAQDGVALQMPTVWRREDPWM
Prediction	634545745030101010000022464332010000223334221441324443254214466055010000000020123204301642703000142003103524056530340444341504604230000200133313121423333213022133120000002325642000000001014342363501000000011123322121410130042050520220525102300441053035006527231420452366451414324302444227
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCCEEEEEEHCCEEEEEHCCEEEEHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCEEEHCCCCCCCCCCHHHHHHHCCCEEEHCHHHHHHHHHHCCCCCCEEEHCCCEEEEHCCEEEEEEHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEHCCCCCEEEEHCCCCCCCHHHCCCCCCEEEHCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEHCCCCCCCCCCCCCHHHHHHHHHHHCCCEEHCCCCCCCCCCCCCCCCCCCCCCCCC
MPTARSDAPLSVTWMGVATLLVDDGSSALMTDGYFSRPGLARVAAGKVSPSAERVDGCLARANVSRLTAVIPVHTHIDHAMDSALVADRTGAQLVGGESAANVGRGYGLPEESLVVAVPGEPIQLGAFDVTLVESHHCPPDRFPGVISAPLTPPVKASAYRCGEAWSTLVHHRPSGRRLLIQDSAGFVSGALAGYRADAAYLSVGQLGLQPPSYLLEYWTETVRTVGVRRVILIHWDDFFRPLSKPLRALPYAADDLDLSIRILDELAAQDGVALQMPTVWRREDPWM

3x2xA

0.13

0.10

0.78

2.64

MUSTER

--------GMKVTFLGHAVVLIEG-KKNIIIDPFISGNPVC----------------PVKLEGLPKIDYILVTAGHGDHLGDAVEIAKKNDATVISNYEICHYLGKKGV---KTHAMHIGGSYLFDFGRVKMTPAVHGSGILDGDS-MIYGGNP------------SGFLITIEGKKIYHAGDTGLTREMELLAENVDVAFLPIGGNF----VMDVEDAVRAAVMIKPKKVVPMHYGTWEL-IFADVELFKKKVEEKGVECVILEPGESLEL----------------

3x2xA

0.13

0.10

0.78

4.76

dPPAS

--------GMKVTFLGHAVVLIEG-KKNIIIDPFISGNPVC----------------PVKLEGLPKIDYILVTAGHGDHLGDAVEIAKKNDATVISNYEICHYLGKKGV---KTHAMHIGGSYLFDFGRVKMTPAVHGSGILDGDSMIYGGNP-------------SGFLITIEGKKIYHAGDTGLTREMELLAENVDVAFLPIGGNF----VMDVEDAVRAAVMIKPKKVVPMHYGTWEL-IFADVELFKKKVEEKGVECVILEPGESLEL----------------

3x2xA

0.14

0.11

0.78

4.71

wdPPAS

--------GMKVTFLGHAVVLIE--KKNIIIDPFISGNPVC----------------PVKLEGLPKIDYILVTAGHGDHLGDAVEIAKKNDATVISNYEICHYLGKKGV---KTHAMHIGGSYLFDFGRVKMTPAVHGSGILDGDS-MIYGGNP------------SGFLITI-EGKKIYHAGDTGLTEMELLAEEVDVAFLPIGGNF----VMDVEDAVRAAVMIKPKKVVPMHYGTWEL-IFADVELFKKKVEEKGVECVILEPGESLEL----------------

4qn9A

0.18

0.16

0.88

2.85

wMUSTER

EEAGVREAGLRVTWLGHATVMVEMDELIFLTDPIFSSRASPSQYMGP----KRFRRSPCTISELPPIDAVLISHNHYDHLDSVIALNERNELRWFVPLGLLDWMQKCGC--ENVIELDWWEENCVPGVTFVFTPSQHWCKRTLMD---------------DNKVLWGSWSVLGPWNRFFFAGDTGYCPAFEEIGGPFDLAAIPIGAYEPRYQHVDPEEAVRIHTDVQTKKSMAIHWGTFNEHYLEPPVKLNEALERYGLNFFVLKHGESRYLNN--------------

3x2xA

0.14

0.10

0.76

4.20

wPPAS

--------GMKVTFLGHAVVLIE--KKNIIIDPFISGNPVC----------------PVKLEGLPKIDYILVTAGHGDHLGDAVEIAKKNDATVISNYEICHYLGKKGV---KTHAMHIGGSYLFDFGRVKMTPAVHGSGI--LD---------------GDSMIYSGFLITI-EGKKIYHAGDTGTREMELLAEEVDVAFLPIGGNF----VMDVEDAVRAAVMIKPKKVVPMHYGTWEL-IFADVELFKKKVEEKGVECVILEPGESLEL----------------

3x2xA

0.13

0.10

0.78

9.21

dPPAS2

--------GMKVTFLGHAVVLIEG-KKNIIIDPFISGNPVC----------------PVKLEGLPKIDYILVTAGHGDHLGDAVEIAKKNDATVISNYEICHYLGKKGV---KTHAMHIGGSYLFDFGRVKMTPAVHGSGILDGDSMIYGGNP-------------SGFLITIEGKKIYHAGDTGLTREMELLAENVDVAFLPIGGNF----VMDVEDAVRAAVMIKPKKVVPMHYGTWEL-IFADVELFKKKVEEKGVECVILEPGESLEL----------------

3x2xA

0.13

0.10

0.77

3.71

PPAS

--------GMKVTFLGHAVVLIEG-KKNIIIDPFISGNPVC----------------PVKLEGLPKIDYILVTAGHGDHLGDAVEIAKKNDATVISNYEICHYLGKKGV---KTHAMHIGGSYLFDFGRVKMTPAVHGSGIL------------------GDSMIYSGFLITIEGKKIYHAGDTGLTREMELLAEEVDVAFLPIGGNF----VMDVEDAVRAAVMIKPKKVVPMHYGTWEL-IFADVELFKKKVEEKGVECVILEPGESLEL----------------

3x2xA

0.13

0.10

0.78

5.28

Env-PPAS

--------GMKVTFLGHAVVLIEG-KKNIIIDPFISGNPVC----------------PVKLEGLPKIDYILVTAGHGDHLGDAVEIAKKNDATVISNYEICHYLGKKGV---KTHAMHIGGSYLFDFGRVKMTPAVHGSGILDGDSMIYGGN-------------PSGFLITIEGKKIYHAGDTGLTREMELLAEEVDVAFLPIGGNF----VMDVEDAVRAAVMIKPKKVVPMHYGTWEL-IFADVELFKKKVEEKGVECVILEPGESLEL----------------

3rpcA

0.13

0.11

0.85

2.26

MUSTER

--------ATQYTHIRNATGKLTIKNTTFLIDPFLAPKDTYPGFEGTFNYQQRPVDLPLSDDLLSNVTAVVVTHTHLDHWDDTAINSIPKSLPIFVNTADKELITSQGFI--DVRII--FESLEFNGITLRKTGGSHGTVEYANPVLAPLAG-------------DAGVIFEAADETVYLVGDTVWTSDVEKALFDPNVIINTGYAQILGFSIIGTKDIGRVVRKPEA-KIIAVH-DTVNH-TATSRKDVRKFIKGNNIHVAVPEDGETITL----------------

3rpcA

0.14

0.12

0.85

4.17

dPPAS

--------ATQYTHIRNATGKLTIKNTTFLIDPFLAPKDTYPGFEGTFNYQQRPVDLPLSDDLLSNVTAVVVTHTHLDHWDDTAINSIPKSLPIFVNTADKELITSQGFID----VRIIFESLEFNGITLRKTGGSHGTVEYANPVLAPLAG-------------DAGVIFEAADEPTVYLGDTVWTSDVEKALLRFDPVIINTGYLGFEDSIIGTKDIGRVVRKPEA-KIIAVHDT--VNHTATSRKDVRKFIKGNNIEVAVPEDGETITL----------------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=0.46

Estimated TM-score = 0.78±0.10

Estimated RMSD = 5.1±3.3Å

Download Model 2

C-score=-1.98

Download Model 3

C-score=-1.22

Download Model 4

C-score=-2.79

Download Model 5

C-score=-2.93

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	3bv6B	0.801	3.26	0.143	0.948
2	4qn9A	0.769	2.80	0.167	0.875
3	3x2xA	0.737	1.61	0.129	0.781
4	3rpcA	0.727	2.80	0.137	0.830
5	5a0tA	0.697	3.47	0.138	0.837
6	4jo0A	0.691	2.78	0.131	0.792
7	4xwtA	0.679	3.59	0.113	0.826
8	3zq4A	0.676	3.52	0.118	0.823
9	2ycbA	0.672	3.12	0.135	0.785
10	3bk1A	0.669	3.55	0.127	0.816

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.49	45	3x2zA	NI	Rep, Mult	78,79,183,235
2	0.35	41	3zq4A	ZN	Rep, Mult	74,76,137,183

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.091	1y44A	0.636	3.06	0.121	0.747	3.1.26.11	NA
2	0.067	2fk6A	0.647	3.11	0.118	0.764	3.1.26.11	NA
3	0.060	2dkfA	0.624	3.14	0.147	0.733	3.1.-.-	110
4	0.060	1ycfA	0.459	4.11	0.076	0.587	1.7.99.7	NA
5	0.060	1e1eB	0.452	6.10	0.053	0.743	3.2.1.21	NA
6	0.060	2uz9A	0.465	5.88	0.059	0.747	3.5.4.3	NA
7	0.060	2cbnA	0.637	3.15	0.128	0.757	3.1.26.11	19,76,78
8	0.060	2qedA	0.464	4.65	0.074	0.625	3.1.2.6	NA
9	0.060	2gmnA	0.458	5.01	0.115	0.646	3.5.2.6	78
10	0.060	3dhaA	0.497	3.62	0.103	0.625	3.1.1.-	NA
11	0.060	1l9yA	0.458	4.28	0.108	0.597	3.5.2.6	78
12	0.060	2i9uA	0.466	6.06	0.042	0.767	3.5.4.3	134
13	0.060	1wdpA	0.457	6.03	0.042	0.733	3.2.1.2	NA
14	0.060	1veoA	0.461	5.78	0.043	0.715	3.2.1.2	86,102
15	0.060	1dwaM	0.457	5.97	0.060	0.722	3.2.1.147	NA
16	0.060	1xm8A	0.468	4.61	0.102	0.628	3.1.2.6	78
17	0.060	2pbgA	0.459	5.52	0.058	0.691	3.2.1.85	NA
18	0.060	3b9eA	0.458	5.57	0.069	0.701	3.2.1.14	NA
19	0.060	2q01C	0.480	5.88	0.065	0.778	5.3.1.12	237
20	0.060	1p9eA	0.485	4.11	0.135	0.625	3.1.8.1	NA
21	0.060	2i7vA	0.661	3.23	0.118	0.781	3.1.27.-	78

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.50	0.801	3.26	0.14	0.95	3bv6B	GO:0046872
1	0.40	0.744	2.81	0.13	0.85	3rpcA	GO:0046872
2	0.39	0.666	3.28	0.16	0.78	3af5A	GO:0003676 GO:0003723 GO:0046872
3	0.38	0.661	3.23	0.12	0.78	2i7vA	GO:0000398 GO:0003723 GO:0004518 GO:0004519 GO:0004521 GO:0005634 GO:0005654 GO:0005847 GO:0006369 GO:0006378 GO:0006379 GO:0006397 GO:0006398 GO:0006406 GO:0008409 GO:0016787 GO:0030529 GO:0031124 GO:0046872 GO:0090305 GO:0090502
4	0.37	0.643	3.17	0.12	0.76	1zkpA	GO:0046872
5	0.36	0.607	3.11	0.14	0.72	3g1pB	GO:0008081 GO:0016787 GO:0019700 GO:0030145 GO:0046872
6	0.33	0.647	3.06	0.12	0.76	1y44A	GO:0004518 GO:0004519 GO:0008033 GO:0008270 GO:0016787 GO:0016891 GO:0034414 GO:0042779 GO:0042781 GO:0046872 GO:0090502
7	0.31	0.771	2.82	0.17	0.88	4qn9B	GO:0001523 GO:0004620 GO:0005737 GO:0006629 GO:0008270 GO:0009395 GO:0016020 GO:0016042 GO:0016787 GO:0042622 GO:0046872 GO:0070062 GO:0070290
8	0.30	0.737	1.61	0.13	0.78	3x2xA	GO:0016787
9	0.30	0.668	3.09	0.16	0.78	2xr1B	GO:0003676 GO:0003723 GO:0046872
10	0.27	0.775	3.04	0.14	0.90	2wylA	GO:0005737 GO:0016787 GO:0019854 GO:0030145 GO:0035460 GO:0052689
11	0.27	0.634	2.65	0.14	0.71	3kl7A	GO:0016787 GO:0046872
12	0.13	0.645	4.58	0.07	0.87	2bibA	GO:0046872
13	0.12	0.697	3.47	0.14	0.84	5a0tA	GO:0003723 GO:0004518 GO:0004519 GO:0004521 GO:0004527 GO:0004534 GO:0005737 GO:0006364 GO:0006396 GO:0008270 GO:0016787 GO:0046872 GO:0090501 GO:0090502 GO:0090503
14	0.11	0.676	3.52	0.12	0.82	3zq4A	GO:0003723 GO:0004518 GO:0004519 GO:0004521 GO:0004527 GO:0004534 GO:0005737 GO:0006364 GO:0006396 GO:0006397 GO:0008270 GO:0016787 GO:0046872 GO:0090501 GO:0090502 GO:0090503
15	0.10	0.691	2.78	0.13	0.79	4jo0A	GO:0046872
16	0.10	0.565	2.93	0.13	0.65	1vjnA	GO:0016787
17	0.10	0.675	3.48	0.12	0.82	3t3oA	GO:0003723 GO:0004518 GO:0004519 GO:0004521 GO:0004527 GO:0004534 GO:0005737 GO:0006364 GO:0006396 GO:0008270 GO:0016787 GO:0046872 GO:0090501 GO:0090502 GO:0090503
18	0.09	0.682	3.44	0.11	0.82	4xwwA	GO:0003723 GO:0004518 GO:0004519 GO:0004521 GO:0004527 GO:0004534 GO:0005737 GO:0006364 GO:0006396 GO:0008270 GO:0016787 GO:0046872 GO:0090501 GO:0090502 GO:0090503
19	0.08	0.659	3.16	0.12	0.78	2i7tA	GO:0000398 GO:0003723 GO:0004518 GO:0004519 GO:0004521 GO:0005634 GO:0005654 GO:0005847 GO:0006369 GO:0006378 GO:0006379 GO:0006397 GO:0006398 GO:0006406 GO:0008409 GO:0016787 GO:0030529 GO:0031124 GO:0046872 GO:0090305 GO:0090502
20	0.08	0.672	3.14	0.14	0.78	2ycbB	GO:0003676 GO:0003723 GO:0046872
21	0.07	0.409	5.51	0.07	0.63	3a4yA	GO:0003723 GO:0004518 GO:0004519 GO:0005737 GO:0006364 GO:0016787 GO:0046872 GO:0090305

Consensus prediction of GO terms

Molecular Function	GO:0046872	GO:0003723	GO:0004521	GO:0008409
GO-Score	0.93	0.62	0.38	0.38
Biological Processes	GO:0006406	GO:0090502	GO:0006369	GO:0006379	GO:0006378	GO:0000398	GO:0006398
GO-Score	0.38	0.38	0.38	0.38	0.38	0.38	0.38
Cellular Component	GO:0030529	GO:0005847
GO-Score	0.38	0.38

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.