Threading Zmax Znorm MUSTER 4.46 0.77 dPPAS 8.37 0.90 wdPPAS 13.06 1.40 wMUSTER 5.30 0.91 wPPAS 7.04 1.01 dPPAS2 10.04 0.96 PPAS 6.22 0.89 Env-PPAS 6.97 0.87 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=7291) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.24 0.45+-0.14 12.0+-4.4 3660 0.110 model2 -3.33 1413 0.037 model3 -3.28 1762 0.039 model4 -3.63 957 0.027 model5 -3.78 183 0.024 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).