I-TASSER results

Input Sequence in FASTA format

>protein (220 residues)
MSDEIDPDWPAPAYQPSDDVDTTPPAPGGSWPTAWLVALVVLACVAAAVVAYAGMHRVRP
GANQAAPATTSAPARPTSPASQVGPCGPDEATAVRAALAQLAPDSKTGRPWNSTPEDSNY
DPCADLSAVLVTVQDATNSSPDQALMFHRGTFVGTATPRAYPFTNLIGPASTNDIVVLSY
RTRQSCDGCQDGILTIVGFAWRGDHVQILDSLPELFDAPP

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 \| \| \| \| \| \| \| \| \| \| \| MSDEIDPDWPAPAYQPSDDVDTTPPAPGGSWPTAWLVALVVLACVAAAVVAYAGMHRVRPGANQAAPATTSAPARPTSPASQVGPCGPDEATAVRAALAQLAPDSKTGRPWNSTPEDSNYDPCADLSAVLVTVQDATNSSPDQALMFHRGTFVGTATPRAYPFTNLIGPASTNDIVVLSYRTRQSCDGCQDGILTIVGFAWRGDHVQILDSLPELFDAPP
Prediction	CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHEEEHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHCCCCCCCCEEEEEEHCCEEHCCCCCCCCCCCCCEHCCCCCCEEEEEEHCCCCCCCCCCCCCEEEEEEEHCCEEEEHCCCCCCCCCCC
Conf.Score	9988999999887789998888999999988765444444444456788888888899999999999999999999999999899999986999999986799999999887777789998887768999996588999877999987997757788998888655555678968999985688888888888668999998998999668998888999
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 \| \| \| \| \| \| \| \| \| \| \| MSDEIDPDWPAPAYQPSDDVDTTPPAPGGSWPTAWLVALVVLACVAAAVVAYAGMHRVRPGANQAAPATTSAPARPTSPASQVGPCGPDEATAVRAALAQLAPDSKTGRPWNSTPEDSNYDPCADLSAVLVTVQDATNSSPDQALMFHRGTFVGTATPRAYPFTNLIGPASTNDIVVLSYRTRQSCDGCQDGILTIVGFAWRGDHVQILDSLPELFDAPP
Prediction	8656254723333343565475444445433221221001111112333333443644535455445554644664655754654246543530352045144546554424343554424412301001031545674332000001544213243642333342444444430000204336456324652304020304664043425126436558
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHEEEHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHCCCCCCCCEEEEEEHCCEEHCCCCCCCCCCCCCEHCCCCCCEEEEEEHCCCCCCCCCCCCCEEEEEEEHCCEEEEHCCCCCCCCCCC
MSDEIDPDWPAPAYQPSDDVDTTPPAPGGSWPTAWLVALVVLACVAAAVVAYAGMHRVRPGANQAAPATTSAPARPTSPASQVGPCGPDEATAVRAALAQLAPDSKTGRPWNSTPEDSNYDPCADLSAVLVTVQDATNSSPDQALMFHRGTFVGTATPRAYPFTNLIGPASTNDIVVLSYRTRQSCDGCQDGILTIVGFAWRGDHVQILDSLPELFDAPP

1mv3A

0.16

0.13

0.82

1.20

wPPAS

-----DG---SPAATPEIRVNEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRVQAQ-HD---YTATDTDE-----------KAGDVVLV---PFQNPEEQDEG--------WLMGVKELEKCFP------P

1mv3A

0.12

0.10

0.82

1.59

dPPAS2

-----DG---SPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLP--------------AVVVETFPATV---------NGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTD---------ELQLKAGDVVLVIPFQNPEEQDE

1mv3A

0.15

0.12

0.81

1.23

PPAS

-----DG---SPAATPEIRVNHEPEPAGGATPGA----------TLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTT-------PSQPAEASEVAGGTQPAAGAQEPGET------AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHYTATDTD----------ELQLKAGDVVLVIPFQNPEEQDE

2xivA

0.16

0.12

0.74

0.97

wPPAS

--GLWDPTLPIPANIPGDPIAVVNQVLGISATSAQVTANGRKFLEQLGILQPTDTGITNAPAGSAQGRIPRVYGRQ-------------ASEYVIRRGSQIGNAAGPSKGIDSGAGTVGFD-CSGLLYS-IKLP-PSSQRRGDVIFYHVTIYLGNGAPDV------------GLKVRV-------APVRTAGTPYVVRY-Y-------------------

5gaoE

0.16

0.14

0.89

1.47

dPPAS2

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA-------AAAAAAAAAAAA---------AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA---------AAAAAAAAAAAAAA

5gaoE

0.15

1.00

1.16

PPAS

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAARAAAAAAAAAAAAAAAAAAAAAAAAAA

4ufqA

0.12

0.11

0.90

1.20

dPPAS2

----ATTTFDGPVAAERFSADTTLEAAFLKTTSETNHAATIYQAGTSGDGAALNVISDNPGTSAYLSGTETARGTLKITHRGYADGSDKDAAALS-----LDLRVAGTAAQGIYVTATNGPTKGNL----IALRNNTGL--DDFVVKGTGIGVGIDRAAPRAQVHIVQRGDALASVRIGNAATVPTSVDSSGGGGALLWRGSNGTVTTIAPA--------

4ufqA

0.11

0.10

0.92

1.13

PPAS

----ATTTFDGPVAAERFSADTTLEAAFLKTTSETNHAATIYQAGTSGDGAALNVISDNPGTSAYLSGTETARGTLKITHRGYADGSDKDAAALS-----LDLRVAGTAAQGIYVTATNGPTKGNL----IALRNNTGLDDFVV-RIGVGIDRA---ATPRAQVHIVQRGDALAALLVEGSVRIGNAATVPTSVDSSALYASGGALLWRGSNGTVTTIAP

3jbmA

0.14

0.10

0.73

1.11

dPPAS2

MSRISQAVLPAGTGTDGYVVVDATIVPDLLPRLGHAARIFQRYAVETLEFEIQPMCPANTGGGYVAGFLPDPTDNDHTFDALQATRGAVVAKWWESRT--VRPQYTRTLLWTSSGKEQRLTSPGRL--ILLCVGNNTDVVNVSVLC--------RWSVRLSVPSLETPEETTA-----------------------------------------------

5c2vC

0.10

0.94

1.04

dPPAS2

FKSELDAAWSLQGSYERGQTTGLIWDLGDEGWGSWKNTKYIRGGRYLPPFRHEGFTGHPDEIVGATSSLDRVCGRDPGFVFRSENFSPMRLEALICYIRALEFTGSPFRNADGSLTEDPKVGCLE----CHPGDPMDPRALFSDAQTHD---VGTGRVGVNGFRSTPGKVFNISALEAGEDPYGVESNTPIIGL-------DLVKEFDTPTLRDIYASGT

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-4.66

Estimated TM-score = 0.23±0.07

Estimated RMSD = 17.1±2.7Å

Download Model 2

C-score=-5.00

Download Model 3

C-score=-5.00

Download Model 4

C-score=-5.00

Download Model 5

C-score=-5.00

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	1mv3A	0.665	3.25	0.128	0.818
2	2w6dA	0.301	5.65	0.000	0.500
3	3og2A	0.300	4.92	0.029	0.464
4	1tg7A	0.292	5.24	0.021	0.464
5	4y21A	0.291	4.86	0.060	0.450
6	3k07A	0.291	5.56	0.030	0.477
7	4tkoB	0.289	5.36	0.024	0.459
8	1ciiA	0.288	5.27	0.022	0.450
9	3ibjA	0.285	5.48	0.048	0.464
10	5hy7A	0.285	5.29	0.031	0.455

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.10	5	1izlD	PHO	Rep, Mult	93,94,97,98
2	0.06	3	5l8gK	CA	Rep, Mult	90,93
3	0.04	2	1dbnA	NAG	Rep, Mult	197,199,213
4	0.02	1	1yklA	DHB	Rep, Mult	84,85,202
5	0.02	1	3lo1A	PG0	Rep, Mult	123,152
6	0.02	1	3fbyC	CA	Rep, Mult	113,121,123,138,139,140,143
7	0.02	1	4gctB	NUC	Rep, Mult	91,95
8	0.02	1	2w6dA	GDP	Rep, Mult	100,101,102,126
9	0.02	1	2yi9A	MG	Rep, Mult	173,210
10	0.02	1	1yklG	DHB	Rep, Mult	84,85
11	0.02	1	1yklC	DHB	Rep, Mult	85,202
12	0.02	1	3fbyC	CA	Rep, Mult	200,202,204,206,213,217
13	0.02	1	2x8fA	CA	Rep, Mult	32,148
14	0.02	1	3kssA	CU1	Rep, Mult	100,126,128
15	0.02	1	2yiuC	SMA	Rep, Mult	123,148
16	0.02	1	1en7B	CA	Rep, Mult	87,90
17	0.02	1	3e1aO	NUC	Rep, Mult	74,75

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	3fwlA	0.245	5.98	0.044	0.427	2.4.1.129	NA
2	0.060	2z9uA	0.186	5.29	0.047	0.300	2.6.1.30	NA
3	0.060	1qssA	0.172	5.45	0.023	0.291	2.7.7.7	96
4	0.060	1eqrA	0.253	5.47	0.025	0.405	6.1.1.12	NA
5	0.060	2hzpA	0.246	5.43	0.026	0.400	3.7.1.3	NA
6	0.060	1cjyA	0.256	5.91	0.055	0.450	3.1.1.4,3.1.1.5	NA
7	0.060	2p0mB	0.243	5.64	0.034	0.418	1.13.11.33	NA
8	0.060	3iydC	0.244	5.60	0.015	0.414	2.7.7.6	128
9	0.060	1ea0A	0.177	4.80	0.000	0.273	1.4.1.13	NA
10	0.060	2vuaA	0.167	5.67	0.016	0.282	3.4.24.69	116,119
11	0.060	1ygeA	0.263	4.79	0.033	0.405	1.13.11.12	NA
12	0.060	2fyfA	0.258	5.54	0.026	0.432	2.6.1.52	NA
13	0.060	1ti2A	0.190	6.47	0.028	0.377	1.97.1.2	NA
14	0.060	2q3zA	0.251	5.11	0.035	0.400	2.3.2.13	NA
15	0.060	2iukA	0.237	5.83	0.029	0.418	1.13.11.12	NA
16	0.060	1bglA	0.254	6.06	0.060	0.450	3.2.1.23	NA
17	0.060	1xc6A	0.286	4.96	0.021	0.450	3.2.1.23	NA
18	0.060	1bgxT	0.240	5.46	0.032	0.414	2.7.7.7	NA
19	0.060	3b43A	0.251	5.53	0.038	0.423	2.7.11.1	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.09	0.665	3.25	0.13	0.82	1mv3A	GO:0005634 GO:0005737 GO:0006897 GO:0006997 GO:0007275 GO:0008283 GO:0015629 GO:0016020 GO:0016032 GO:0030018 GO:0030100 GO:0030154 GO:0030315 GO:0030424 GO:0031674 GO:0033268 GO:0042692 GO:0042802 GO:0043065 GO:0043194 GO:0045664 GO:0048156 GO:0048711 GO:0051015 GO:0060987 GO:0060988 GO:0070063 GO:0071156
1	0.06	0.170	5.37	0.03	0.28	2vgeA	GO:0000122 GO:0003215 GO:0003229 GO:0003714 GO:0005634 GO:0005654 GO:0005737 GO:0005913 GO:0006351 GO:0006355 GO:0006915 GO:0008134 GO:0009791 GO:0030054 GO:0031076 GO:0035264 GO:0042633 GO:0042802 GO:0045171 GO:0045597 GO:0048871 GO:0060048 GO:0098609 GO:0098641 GO:1901796
2	0.06	0.148	4.12	0.08	0.20	1wxuA	GO:0000268 GO:0001561 GO:0001764 GO:0001967 GO:0002230 GO:0005777 GO:0005778 GO:0005779 GO:0006810 GO:0007626 GO:0015031 GO:0016020 GO:0016021 GO:0016560 GO:0021795 GO:0043231 GO:0060152 GO:0098779 GO:0098792
3	0.06	0.119	4.08	0.06	0.17	2e5kA	GO:0004721 GO:0004725 GO:0005634 GO:0005737 GO:0006469 GO:0009968 GO:0016787 GO:0035335 GO:0045670 GO:0045671 GO:0045779 GO:0051279 GO:0090331
4	0.06	0.157	3.65	0.07	0.20	2ed0A	GO:0003677 GO:0005737 GO:0005829 GO:0005856 GO:0006928 GO:0007010 GO:0008093 GO:0008154 GO:0016032 GO:0016477 GO:0016601 GO:0017124 GO:0018108 GO:0019900 GO:0030027 GO:0030175 GO:0031209 GO:0031625 GO:0032403 GO:0042995 GO:0048365 GO:0070064 GO:2000601
5	0.06	0.118	5.00	0.06	0.20	1ug1A	GO:0005085 GO:0005089 GO:0005737 GO:0005794 GO:0005795 GO:0005856 GO:0030054 GO:0035023 GO:0035556 GO:0043547 GO:0045202
6	0.06	0.110	4.99	0.07	0.17	1pnjA	GO:0001678 GO:0001953 GO:0005068 GO:0005158 GO:0005159 GO:0005168 GO:0005634 GO:0005737 GO:0005801 GO:0005829 GO:0005911 GO:0005942 GO:0005943 GO:0006468 GO:0006810 GO:0007162 GO:0007165 GO:0008134 GO:0008286 GO:0008625 GO:0008630 GO:0014065 GO:0015031 GO:0016020 GO:0019903 GO:0030183 GO:0030335 GO:0032760 GO:0032869 GO:0033120 GO:0034644 GO:0034976 GO:0035014 GO:0036312 GO:0042993 GO:0043066 GO:0043125 GO:0043548 GO:0043551 GO:0043559 GO:0043560 GO:0045671 GO:0045944 GO:0046326 GO:0046854 GO:0046935 GO:0046982 GO:0048009 GO:0050821 GO:0051492 GO:0051531 GO:0060396 GO:0090003 GO:0090004 GO:1900103 GO:1990578 GO:2001275
7	0.06	0.157	3.77	0.06	0.21	1x2qA	GO:0005654 GO:0005737 GO:0005768 GO:0005829 GO:0006810 GO:0006886 GO:0006914 GO:0015031 GO:0016020 GO:0016197 GO:0031901 GO:0033565 GO:0036258 GO:0042059 GO:0043231
8	0.06	0.136	3.92	0.10	0.19	2ysqA	GO:0005085 GO:0005089 GO:0005737 GO:0005829 GO:0034220 GO:0035023 GO:0043065 GO:0043547 GO:0051056
9	0.06	0.141	6.04	0.03	0.25	4a63B	GO:0002039 GO:0005070 GO:0005634 GO:0005654 GO:0005737 GO:0005739 GO:0006915 GO:0007049 GO:0007165 GO:0017124 GO:0042802 GO:0042981 GO:0045786 GO:0048471 GO:0051059 GO:0072332 GO:1900119 GO:1900740 GO:1901216 GO:1901796
10	0.06	0.156	3.71	0.04	0.20	1udlA	GO:0005070 GO:0005089 GO:0005509 GO:0005737 GO:0005813 GO:0006897 GO:0009967 GO:0030154 GO:0035023 GO:0043547 GO:0046872 GO:0070062 GO:1903861
11	0.06	0.146	3.45	0.13	0.19	1ujyA	GO:0005085 GO:0005089 GO:0005096 GO:0005622 GO:0005829 GO:0006915 GO:0007254 GO:0030027 GO:0030032 GO:0035023 GO:0042995 GO:0043065 GO:0043547 GO:0051056
12	0.06	0.107	4.14	0.00	0.15	2ct3A	GO:0000122 GO:0005200 GO:0005634 GO:0005737 GO:0005829 GO:0005856 GO:0005925 GO:0006936 GO:0007015 GO:0007155 GO:0008134 GO:0017166 GO:0030054 GO:0031589 GO:0043410 GO:0051495 GO:0051496
13	0.06	0.147	3.57	0.11	0.20	2yunA	GO:0003677 GO:0005634 GO:0005737 GO:0005856 GO:0005886 GO:0006897 GO:0007165 GO:0016020 GO:0016023 GO:0030666 GO:0031410 GO:0045892 GO:0050999
14	0.06	0.153	3.49	0.07	0.20	2k9gA	GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005911 GO:0005925 GO:0006897 GO:0006915 GO:0007010 GO:0007267 GO:0008360 GO:0016020 GO:0016477 GO:0017124 GO:0030054 GO:0030139 GO:0030659 GO:0031410 GO:0042059 GO:0043005 GO:0045202
15	0.06	0.148	3.41	0.17	0.19	2jt4A	GO:0000147 GO:0003779 GO:0005634 GO:0005737 GO:0005768 GO:0005856 GO:0005886 GO:0005938 GO:0006897 GO:0008092 GO:0010008 GO:0016020 GO:0030041 GO:0030479 GO:0030674 GO:0042802 GO:0043130
16	0.06	0.145	3.50	0.05	0.19	2yuoA	GO:0005096 GO:0005622 GO:0005737 GO:0005829 GO:0005921 GO:0006886 GO:0007049 GO:0007050 GO:0012505 GO:0017137 GO:0030695 GO:0031338 GO:0032483 GO:0032486 GO:0045732 GO:0048227 GO:0090630
17	0.06	0.145	4.22	0.06	0.20	3nmzC	GO:0005085 GO:0005089 GO:0005737 GO:0005829 GO:0005886 GO:0016020 GO:0019904 GO:0030032 GO:0030676 GO:0032587 GO:0035023 GO:0035556 GO:0042995 GO:0043065 GO:0043547 GO:0046847 GO:0051056
18	0.06	0.103	3.68	0.08	0.14	2lj0A	GO:0001725 GO:0003779 GO:0005070 GO:0005158 GO:0005634 GO:0005654 GO:0005737 GO:0005813 GO:0005829 GO:0005856 GO:0005886 GO:0005899 GO:0005912 GO:0005913 GO:0005915 GO:0005924 GO:0005925 GO:0006810 GO:0006936 GO:0007015 GO:0007160 GO:0008092 GO:0008286 GO:0009967 GO:0015758 GO:0016020 GO:0016363 GO:0030054 GO:0032869 GO:0043149 GO:0045121 GO:0045725 GO:0046326 GO:0046889 GO:0048041 GO:0090004

Consensus prediction of GO terms

Molecular Function	GO:0042802	GO:0051015	GO:0070063	GO:0048156	GO:0031625	GO:0017124	GO:0098641	GO:0003714	GO:0004725	GO:0000268	GO:0008093	GO:0048365	GO:0008134	GO:0003677	GO:0070064	GO:0019900
GO-Score	0.14	0.09	0.09	0.09	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06
Biological Processes	GO:0006997	GO:0045664	GO:0048711	GO:0060988	GO:0008283	GO:0030100	GO:0042692	GO:0071156	GO:0043065	GO:0060152	GO:0045779	GO:0016601	GO:0009968	GO:0090331	GO:0035335	GO:0001967	GO:0003229	GO:2000601	GO:1901796	GO:0051279	GO:0060048	GO:0006469	GO:0035264	GO:0021795	GO:0001561	GO:0031076	GO:0009791	GO:0001764	GO:0098779	GO:0007626	GO:0000122	GO:0045671	GO:0098792	GO:0016560	GO:0042633	GO:0002230	GO:0018108	GO:0003215
GO-Score	0.09	0.09	0.09	0.09	0.09	0.09	0.09	0.09	0.09	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06
Cellular Component	GO:0043231
GO-Score	0.40

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv3483c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]