Threading Zmax Znorm MUSTER 7.42 1.28 dPPAS 9.98 1.07 wdPPAS 8.59 0.92 wMUSTER 7.03 1.21 wPPAS 9.12 1.30 dPPAS2 13.28 1.26 PPAS 11.71 1.67 Env-PPAS 9.43 1.18 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=5955) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.66 0.41+-0.14 15.8+-3.2 1338 0.056 model2 -2.74 933 0.052 model3 -2.59 510 0.061 model4 -3.81 471 0.018 model5 -3.81 375 0.018 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).