I-TASSER results

I-TASSER results for job id Rv3466

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (222 residues)
MGSGSRERIVEVFDALDAELDRLDEVSFEVLTTPERLRSLERLECLVRRLPAVGHALINQ
LDAQASEEELGGTLCCALANRLRITKPDAARRIADAADLGPRRALTGEPLAPQLTATATA
QRQGLIGEAHVKVIRALFRPPARRGGCVHPPGRRSRPGRQSRSISSRRAGPLRPAGHGLA
TPRRRPHRHRTRPQTRHHPEQPAIRRHVTAKWLPDPPSAGHL

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 \| \| \| \| \| \| \| \| \| \| \| MGSGSRERIVEVFDALDAELDRLDEVSFEVLTTPERLRSLERLECLVRRLPAVGHALINQLDAQASEEELGGTLCCALANRLRITKPDAARRIADAADLGPRRALTGEPLAPQLTATATAQRQGLIGEAHVKVIRALFRPPARRGGCVHPPGRRSRPGRQSRSISSRRAGPLRPAGHGLATPRRRPHRHRTRPQTRHHPEQPAIRRHVTAKWLPDPPSAGHL
Prediction	CCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
Conf.Score	998876899999999999999999698656997999999999999999989988999999886566554588799999999799978999999999998764468898889878899999998999999999999998565557755565677777789999999999998699999998889998747677667788667799999988756788888889
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 \| \| \| \| \| \| \| \| \| \| \| MGSGSRERIVEVFDALDAELDRLDEVSFEVLTTPERLRSLERLECLVRRLPAVGHALINQLDAQASEEELGGTLCCALANRLRITKPDAARRIADAADLGPRRALTGEPLAPQLTATATAQRQGLIGEAHVKVIRALFRPPARRGGCVHPPGRRSRPGRQSRSISSRRAGPLRPAGHGLATPRRRPHRHRTRPQTRHHPEQPAIRRHVTAKWLPDPPSAGHL
Prediction	864453640340043034014303703164034620140044124022314114240033035463355232301400131130345514321430462053321645403342340141144340355004002400520561354243653454345504520430143033425445565545554444466453263221242021411343474557
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
MGSGSRERIVEVFDALDAELDRLDEVSFEVLTTPERLRSLERLECLVRRLPAVGHALINQLDAQASEEELGGTLCCALANRLRITKPDAARRIADAADLGPRRALTGEPLAPQLTATATAQRQGLIGEAHVKVIRALFRPPARRGGCVHPPGRRSRPGRQSRSISSRRAGPLRPAGHGLATPRRRPHRHRTRPQTRHHPEQPAIRRHVTAKWLPDPPSAGHL

3b6aA

0.12

0.11

0.95

1.11

dPPAS2

MAPLTQDRIVVTALGILDAEG-LDALSMRRLAQELKTGHASLYAHVGNRDELLDLVFDIVLTEVEVPEPEPGRWAEQVKEMCR-SLRRMFLAHRDLARIAIDRVPLGPNGMVGMERTMNLLRSGGLHDELAAYGGDLLSTFVTAEALEQSSRQGREQAGVFADQLHGYLKSLPAT----SFPNLVHLAGPITSLDSD-RRFELGLEIIIAGLLAGEAA----

2hxoA

0.17

0.14

0.86

1.05

dPPAS2

---------LSRERIVGAAVELLDTVGERGLTFRALAERLATITGKAELLGAATDAVVTAAVT-AGPTGAADSPQDAVRAVALGLWDATEAHPWLATQLATQLSRTWGTVAPRIFESLGRQVQAGVPEAHWFTASSALHY-------ILGAAGQNAANDEFLDTVSTAWEGLDPD----AYPFTRAVADQVRGHDDR-EQFLAGITLVLTGITP--------

3b6aA

0.12

0.95

0.90

MUSTER

MAPLTQDRIVVTALGILDAE--LDALSMRRLAQELKTGHASLYAHVGNRDELLDLVFDIVLTEVEVPEPEPGRWAEQVKEMCR-SLRRMFLAHRDLARIAIDRVPLGPNGMVGMERTMNLLRSGGLHDELAAYGGDLLSTFVTAEALEQSSRQGREQAGVFADQLHGYLKSLPAT----SFPNLVHLAGPITSLDSD-RRFELGLEIIIAGLLAGAGEAA--

3b6aA

0.12

0.11

0.96

0.81

dPPAS

MAPLTQDRIVVTALGILDAEG-LDALSMRRLAQELKTGHASLYAHVGNRDELLDLVFDIVLTEVEVPEPEPGRWAEQVKEMCR-SLRRMFLAHRDLARIAIDRVPLGPNGMVGMERTMNLLRSGGLHDELAAYGGDLLSTFVTAEALEQSSRQGREQAGVFADQLHGYLKSLPAT-SFPNLVHLAGPITSLDSDRRFELGLEIIIAGLLAGAGEAA------

3b6aA

0.12

0.11

0.95

0.72

wdPPAS

MAPLTQDRIVVTALGILDAEG-LDALSMRRLAQELHASLYAHVGNRDELLDLVFDIVLTEV---EVPEPEPGRWAEQVKEMCR-SLRRMFLAHRDLARIAIDRVPLGPNGMVGMERTMNLLRSGGLHDELAAYGGDLLSTFVTAEALEQSSRQGREQAGVFADQLHGYLKSLPAT-SFPNLVHLAGPITSLDSDRRFELGLEIIIAGLLAGAGEAA------

3b6aA

0.14

0.13

0.91

0.82

wMUSTER

APLTQDRIVVTALGILDAELDAL---SMRRLGHASLYAHVGN------RDELLDLVFDIVLTEVEVPEPEPGRWAEQVKEMCR-SLRRMFLAHRDLARIAIDRVPLGPNGMVGMERTMNLLRSGGLHDELAAYGGDLLSTF--VTAEALEQSSRREQAGVFADQLHGYLKSLPAT----SFPNLVHLAGPITSLDSD-RRFELGLEIIIAGLLAGEAA----

3b6aA

0.12

0.10

0.89

0.83

wPPAS

MAPLTQ------DRIVVTALGILDAEGLDALSMRRLAQEL-GHASLYAHVG--RDELLDLVFDIEVPEPEPGRWAEQVKEMCR-SLRRMFLA--LARIAIDRVPLGPNGMV-GMERTMNLLRSGGLHDELAAYGGDLLST---VTAEALEQSSRQEQAGVFADQLHGYLKSLPAT----SFPNLVHLAGPITSLDSD-RRFELGLEIIIAGLLAGEAA----

5cwcA

0.12

0.11

0.86

1.00

dPPAS2

---SEKEELRERLVKICVENAKRKGDDTEE-AREAAREAFELVREAAERAGIDSSEVLELAIRLIKECVENAQREGYDISEACRAAAEAFKRVAEAAKRAGITSSEVLELALIKECVENAQREGYDISEACRAAAEAFKRVAEAAKGITSSETLKRAIEEIRKRVEEAQRE------GNDISEACRQA---------AEEFRKKAEELKRR-----------

3b6aA

0.11

0.95

1.00

PPAS

MAPLTQDRIVVTALGILDAE--LDALSMRRLAQELKTGHASLYAHVGNRDELLDLVFDIVLTEVEVPEPEPGRWAEQVKEMCRSLRRMFLAHRDLARIAIDRVPLGPNGMV-GMERTMNLLRSGGLHDELAAYGGDLLSTFVTAEALEQSSRQGREQAGVFADQLHGYLKSLPAT----SFPNLVHLAGPITSLDSD-RRFELGLEIIIAGLLAGEAA----

1ad3A1

0.13

0.12

0.87

0.75

Env-PPAS

--------------SISDTVKRAREA-FNSGKTRSLQFRIQQLEALQRMINENLKSISGALAS-----DLGKNEWTSYYEEVAHVLEELDTTIKELPDWADEPVAKTRQTQQDIQPMVGAVAAGEVSGHMADLLATLIP--QYMDQNLGVPETTELLTAVGKIVMAAAAKHLTPGFGGV------GNSGMGAYHGKKSFETFSHRRSCLVKLLNEEAHKARY

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-0.61

Estimated TM-score = 0.64±0.13

Estimated RMSD = 6.9±4.1Å

Download Model 2

C-score=-3.63

Download Model 3

C-score=-4.70

Download Model 4

C-score=-4.63

Download Model 5

C-score=-5.00

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	3b6aA	0.883	1.78	0.123	0.955
2	2y2zA	0.789	2.83	0.094	0.955
3	3bqyA	0.754	2.50	0.118	0.878
4	2vprA	0.743	2.55	0.062	0.869
5	2o7oA	0.740	3.10	0.079	0.905
6	2hxiB	0.737	2.53	0.114	0.869
7	3zqiA	0.733	3.03	0.091	0.887
8	2hxoA	0.726	3.07	0.141	0.892
9	2g7gA	0.703	2.97	0.115	0.865
10	2g7lA	0.697	3.09	0.127	0.860

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.15	14	3b6aE	ZCT	Rep, Mult	61,65,66,67,85,100,101,103,105,109,110,113,114,136,139
2	0.08	8	2ns8C	III	Rep, Mult	61,64,104,105,106,114,117,118,132,135,136,140
3	0.05	5	3zqlB	QNA	Rep, Mult	38,40,41,44,45
4	0.03	3	3b6cB	SDN	Rep, Mult	61,65,67,81,109,110,113,117,139
5	0.02	2	3lsjA	COA	Rep, Mult	78,124,209,210,213
6	0.02	2	2ns70	III	Rep, Mult	103,115,128,129,130,132,133,137,140,141,143,144,145,147,148,168,169,170,195,199,200,203,207,208,210,211,212,214
7	0.02	2	3angD	DCC	Rep, Mult	164,168,172,185,187,188
8	0.02	2	3lspA	QNA	Rep, Mult	27,28,29,33,40,43
9	0.01	1	3b6cA	SDN	Rep, Mult	113,116,117,120
10	0.01	1	1b48A	GSH	Rep, Mult	14,48
11	0.01	1	2wse1	CLA	Rep, Mult	104,107
12	0.01	1	3zqlA	QNA	Rep, Mult	27,28,29,39,40,43,47,48
13	0.01	1	3mi1B	FE	Rep, Mult	117,127
14	0.01	1	3l26B	MG	Rep, Mult	172,174,176
15	0.01	1	1bjyB	CTC	Rep, Mult	54,58,61
16	0.01	1	1vf2A	GTX	Rep, Mult	21,48
17	0.01	1	3c9iB	XE	Rep, Mult	78,82
18	0.01	1	3aqtA	RCO	Rep, Mult	74,77,78,81,119,120,124
19	0.01	1	3aqtB	RCO	Rep, Mult	66,78,81,82,85,116,117,120,139
20	0.01	1	3anpD	DCC	Rep, Mult	140,143,144,147,148

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	2yyjA	0.431	5.27	0.081	0.671	1.14.13.3	NA
2	0.060	1kwgA	0.429	6.09	0.070	0.793	3.2.1.23	NA
3	0.060	1e5dA	0.411	5.42	0.045	0.676	1.-.-.-	67,82
4	0.060	1fa9A	0.422	5.18	0.063	0.658	2.4.1.1	NA
5	0.060	2weiA	0.306	6.35	0.042	0.563	2.7.1.17	86,99
6	0.060	3ffzA	0.426	5.67	0.030	0.725	3.4.24.69	25
7	0.060	1n6bA	0.420	5.56	0.077	0.689	1.14.14.1	11
8	0.060	2i2xA	0.442	4.97	0.079	0.671	2.1.1.90	100
9	0.060	3m07A	0.422	5.61	0.074	0.721	3.2.1.141	87
10	0.060	3c6gB	0.422	5.23	0.036	0.671	1.14.13.15	78,85,137,142
11	0.060	3i3kA	0.421	5.13	0.036	0.644	1.14.13.70	NA
12	0.060	3juvA	0.418	5.22	0.045	0.658	1.14.13.70	78,85
13	0.060	3cf4A	0.427	5.09	0.060	0.671	1.2.99.2	84
14	0.060	2w0aA	0.371	6.07	0.064	0.676	1.14.13.70	NA
15	0.060	3ikmD	0.424	6.10	0.053	0.761	2.7.7.7	NA
16	0.060	1xc6A	0.440	5.79	0.039	0.766	3.2.1.23	54
17	0.060	1z11A	0.423	5.48	0.054	0.703	1.14.14.1	NA
18	0.060	2z1qB	0.418	5.21	0.082	0.676	1.3.99.3	NA
19	0.060	1og5B	0.423	5.56	0.059	0.694	1.14.13.48,1.14.13.49,1.14.13.80	78,134,142

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.36	0.883	1.78	0.12	0.95	3b6aA	GO:0003677 GO:0006351 GO:0006355 GO:0045892 GO:0046677
1	0.32	0.553	3.93	0.10	0.77	4ichA	GO:0003677 GO:0006351 GO:0006355
2	0.28	0.800	2.86	0.09	0.97	2y31A	GO:0003677 GO:0006351 GO:0006355 GO:0045892
3	0.28	0.747	2.49	0.11	0.88	2hxiB	GO:0003677 GO:0006351 GO:0006355 GO:0045892
4	0.27	0.700	3.60	0.08	0.91	3zqgA	GO:0003677 GO:0006351 GO:0006355 GO:0045892 GO:0046677 GO:0046872
5	0.25	0.770	2.50	0.11	0.90	3bqyA	GO:0003677 GO:0006351 GO:0006355 GO:0045892 GO:0046677
6	0.24	0.664	2.91	0.09	0.81	3zqfA	GO:0003677 GO:0006351 GO:0006355 GO:0045892 GO:0046677 GO:0046872
7	0.23	0.737	3.08	0.08	0.90	4auxA	GO:0003677 GO:0006351 GO:0006355 GO:0045892 GO:0046677 GO:0046872
8	0.22	0.734	3.06	0.14	0.90	2hxoA	GO:0003677 GO:0006351 GO:0006355 GO:0045892
9	0.22	0.732	3.21	0.06	0.93	1z0xA	GO:0003677 GO:0006351 GO:0006355 GO:0045892 GO:0046677
10	0.21	0.707	3.03	0.12	0.87	2g7lA	GO:0003677 GO:0006351 GO:0006355 GO:0045892
11	0.20	0.743	2.55	0.06	0.87	2vprA	GO:0003677 GO:0006351 GO:0006355 GO:0045892 GO:0046677 GO:0046872
12	0.18	0.596	3.60	0.12	0.78	3on2B	GO:0003677 GO:0006351 GO:0006355
13	0.18	0.562	2.77	0.11	0.68	3fiwA	GO:0003677 GO:0006351 GO:0006355 GO:0045892 GO:0046677
14	0.18	0.581	3.40	0.07	0.74	3bniA	GO:0003677 GO:0006351 GO:0006355
15	0.17	0.614	3.22	0.11	0.75	3bjbB	GO:0003677 GO:0006351 GO:0006355
16	0.17	0.589	3.49	0.14	0.77	2np5A	GO:0003677 GO:0006351 GO:0006355
17	0.16	0.528	4.06	0.07	0.73	2zcnD	GO:0003677 GO:0006351 GO:0006355
18	0.16	0.601	3.27	0.13	0.77	2f07A	GO:0003677 GO:0006351 GO:0006355
19	0.16	0.547	3.84	0.10	0.73	4za6A	GO:0003677
20	0.16	0.566	3.51	0.10	0.75	3he0C	GO:0003677 GO:0006351 GO:0006355
21	0.14	0.546	3.75	0.10	0.74	3g7rB	GO:0003677 GO:0003700 GO:0006351 GO:0006355
22	0.12	0.528	3.96	0.08	0.73	3vprA	GO:0003677 GO:0006351 GO:0006355 GO:0042802
23	0.11	0.545	3.91	0.07	0.73	4me9A	GO:0003677 GO:0006351 GO:0006355
24	0.11	0.554	3.38	0.10	0.71	4hkuA	GO:0003677 GO:0006351 GO:0006355
25	0.10	0.528	4.29	0.06	0.77	2wuiA	GO:0003677 GO:0006351 GO:0006355
26	0.09	0.527	4.10	0.07	0.73	3geuA	GO:0003677 GO:0006351 GO:0006355
27	0.08	0.631	2.90	0.12	0.77	1zk8A	GO:0003677 GO:0006351 GO:0006355
28	0.07	0.557	3.77	0.07	0.75	3qkxA	GO:0003677 GO:0006351 GO:0006355
29	0.07	0.553	3.28	0.08	0.71	2dg8B	GO:0003677 GO:0006351 GO:0006355
30	0.07	0.541	4.05	0.14	0.75	2genA	GO:0003677 GO:0003700 GO:0006351 GO:0006355
31	0.07	0.586	4.00	0.06	0.80	1t33A	GO:0003677 GO:0003700 GO:0006351 GO:0006355
32	0.07	0.538	3.90	0.13	0.74	2nx4A	GO:0003677 GO:0006351 GO:0006355
33	0.07	0.608	3.57	0.08	0.80	3c07A	GO:0003677 GO:0006351 GO:0006355
34	0.07	0.548	4.27	0.09	0.78	3vibC	GO:0003677 GO:0006351 GO:0006355
35	0.07	0.558	3.80	0.04	0.75	2hyjA	GO:0003677 GO:0003700 GO:0006351 GO:0006355

Consensus prediction of GO terms

Molecular Function	GO:0003677	GO:0043169
GO-Score	0.83	0.55
Biological Processes	GO:0045892	GO:0046677
GO-Score	0.76	0.53
Cellular Component
GO-Score

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.