Threading Zmax Znorm MUSTER 4.38 0.76 dPPAS 7.40 0.80 wdPPAS 8.04 0.86 wMUSTER 5.29 0.91 wPPAS 6.30 0.90 dPPAS2 12.00 1.14 PPAS 6.19 0.88 Env-PPAS 5.79 0.72 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=18549) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.84 0.39+-0.13 11.3+-4.5 6653 0.067 model2 -3.32 3076 0.041 model3 -3.44 3055 0.037 model4 -5.00 490 0.005 model5 -4.12 1677 0.019 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).