I-TASSER results

Input Sequence in FASTA format

>protein (232 residues)
MHLMIPAEYISNVIYEGPRADSLYAADQRLRQLADSVRTTAESLNTTLDELHENWKGSSS
EWMADAALRYLDWLSKHSRQILRTARVIESLVMAYEETLLRVVPPATIANNREEVRRLIA
SNVAGGKHSSNRRPRGTIRAVPGRKYPSNGPLSKLDPICAIEAAPMAGAAADPQERVGPR
GRRGLAGQQQCRGRPGPSLRCSHDTPRFQMNQAFHTMVNMLLTCFACQEKPR

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 \| \| \| \| \| \| \| \| \| \| \| MHLMIPAEYISNVIYEGPRADSLYAADQRLRQLADSVRTTAESLNTTLDELHENWKGSSSEWMADAALRYLDWLSKHSRQILRTARVIESLVMAYEETLLRVVPPATIANNREEVRRLIASNVAGGKHSSNRRPRGTIRAVPGRKYPSNGPLSKLDPICAIEAAPMAGAAADPQERVGPRGRRGLAGQQQCRGRPGPSLRCSHDTPRFQMNQAFHTMVNMLLTCFACQEKPR
Prediction	CCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
Conf.Score	9888985566554567999588999999999999999999999999999874788788999999999999999999999999999999999999999998699999999999999999998547887579999999999999988766777765588777888888888888766667654567765556667888876788887545677899999999887643577889
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 \| \| \| \| \| \| \| \| \| \| \| MHLMIPAEYISNVIYEGPRADSLYAADQRLRQLADSVRTTAESLNTTLDELHENWKGSSSEWMADAALRYLDWLSKHSRQILRTARVIESLVMAYEETLLRVVPPATIANNREEVRRLIASNVAGGKHSSNRRPRGTIRAVPGRKYPSNGPLSKLDPICAIEAAPMAGAAADPQERVGPRGRRGLAGQQQCRGRPGPSLRCSHDTPRFQMNQAFHTMVNMLLTCFACQEKPR
Prediction	7334311020002033221110022013103300440230031022001203441312002101300320231023003304410330420010132034332423312311431120212210011132433322312213111211232234134244354344444444356432444554444555454445331524674241424400310021001001035558
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
MHLMIPAEYISNVIYEGPRADSLYAADQRLRQLADSVRTTAESLNTTLDELHENWKGSSSEWMADAALRYLDWLSKHSRQILRTARVIESLVMAYEETLLRVVPPATIANNREEVRRLIASNVAGGKHSSNRRPRGTIRAVPGRKYPSNGPLSKLDPICAIEAAPMAGAAADPQERVGPRGRRGLAGQQQCRGRPGPSLRCSHDTPRFQMNQAFHTMVNMLLTCFACQEKPR

2g38B

0.26

0.19

0.75

2.17

MUSTER

AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLMDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLR---VSDALSKLTPWKAPPPIA--------------------------------------------------------

2g38B

0.27

0.19

0.71

2.32

dPPAS

AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLMDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLRTPWKAPPPIA-------------------------------------------------------------------

2g38B

0.27

0.19

0.71

3.62

wdPPAS

AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLMDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRL-TPWKAPPPIA-------------------------------------------------------------------

2g38B

0.26

0.19

0.74

2.70

wMUSTER

-FEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLMDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLR---VSDALSKLTPWKAPPPIA--------------------------------------------------------

2g38B

0.27

0.19

0.71

4.53

wPPAS

AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLMDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRL-TPWKAPPPIA-------------------------------------------------------------------

2g38B

0.27

0.19

0.71

5.78

dPPAS2

AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLMDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLRTPWKAPPPIA-------------------------------------------------------------------

2g38B

0.27

0.19

0.71

3.33

PPAS

AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLMDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRL-TPWKAPPPIA-------------------------------------------------------------------

2g38B

0.27

0.19

0.71

4.22

Env-PPAS

AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLMDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLRTPWKAPPPIA-------------------------------------------------------------------

4ke2A

0.11

0.09

0.84

0.88

MUSTER

-------------MNI---DPAARAAAAAAASKAAVTAADAAAAAATIAASAAS---VAAATAADDAAASIATINAASAAAKSIAAAAAMAAKDTAAAAAS-AAAAAVASAAKALET--------INVKAAYAAATTANTAAAAAAATATTAAAAAAAKATIDNAAAAKAAAVATAVSDAAATAATAAAVAAATLEAA---AAKAAATAVSAAAAAAAAAIAFAAA----P-

4ke2A

0.12

0.10

0.84

0.97

dPPAS

---------------MNIDPAARAAAAAAASKAAVTAADAAAAAATIAASAASVAAATAADDAAASIATINAASAAAKSIAAAAAMAAKDTAAAAASAAAAAVASAAKALETINVKAAYAAATTANTAAAAAAATATTAAAAAAAKATIDNAAAAKAAAVATAVSDAAATAATAAAVAAATLEAAAAKAA----------------ATAVSAAAAAAAAAIAFAAAP-----

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-1.52

Estimated TM-score = 0.53±0.15

Estimated RMSD = 9.0±4.6Å

Download Model 2

C-score=-1.78

Download Model 3

C-score=-3.42

Download Model 4

C-score=-3.10

Download Model 5

C-score=-3.29

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	2g38B	0.709	1.49	0.249	0.746
2	5c1fA	0.615	4.93	0.066	0.957
3	4dylA1	0.615	4.87	0.050	0.922
4	2eflA	0.612	4.50	0.070	0.901
5	4nqiA	0.606	4.24	0.064	0.828
6	4wpcA	0.601	4.60	0.085	0.866
7	3g9gA	0.598	4.27	0.078	0.841
8	2d4cB	0.592	3.83	0.057	0.797
9	5ebzA	0.588	4.32	0.061	0.845
10	4hpqC	0.586	4.08	0.054	0.802

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.08	3	5ebzD	5LS	Rep, Mult	70,74,182
2	0.06	2	1mz9B	VDY	Rep, Mult	30,33,37
3	0.06	2	1nf4A	FE2	Rep, Mult	37,74,77,174
4	0.03	1	2vs0B	ZN	Rep, Mult	35,82
5	0.03	1	1hjbA	NUC	Rep, Mult	69,70,73,74,76,77,80
6	0.03	1	1i4d1	III	Rep, Mult	35,38,41,42,45,46,48,49,50,52,53,68,71,75,78,79
7	0.03	1	2j9tA	BO3	Rep, Mult	97,98,101,148,149,152
8	0.03	1	1wdz0	III	Rep, Mult	17,22,26,29,30,33,36,37,39,40,43,46,47,50,51,56,57,60,63,66,67,70,74,88,166,167,168,185
9	0.03	1	2gdcA	III	Rep, Mult	14,19,22,23,26,27,30,33,77,170
10	0.03	1	1zww0	III	Rep, Mult	19,22,23,25,26,29,33,36,39,46,47,50,53,63,170,171,174,175,178,179,181,182,185,186,188,189,193,196,197
11	0.03	1	4j4qA	BOG	Rep, Mult	112,138,141
12	0.03	1	3o02B	JN3	Rep, Mult	90,94,148,151,152,155
13	0.03	1	2g38B	MN	Rep, Mult	139,142,143
14	0.03	1	2g381	III	Rep, Mult	2,13,14,16,17,18,19,22,23,26,29,30,32,33,36,37,39,40,43,44,47,51,55,63,70,73,81,84,88,95,152,153,156,158,161,166

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	1serB	0.363	4.64	0.068	0.522	6.1.1.11	101,139
2	0.060	2e9fB	0.436	4.42	0.069	0.608	4.3.2.1	NA
3	0.060	1z0hB	0.226	5.81	0.083	0.371	3.4.24.69	NA
4	0.060	3e04D	0.447	4.43	0.065	0.612	4.2.1.2	87,94
5	0.060	3ixzA	0.427	5.43	0.033	0.685	3.6.3.10	NA
6	0.060	3gtdA	0.446	4.45	0.062	0.616	4.2.1.2	127
7	0.060	1k62B	0.437	4.13	0.061	0.591	4.3.2.1	127
8	0.060	1y2mB	0.468	5.45	0.067	0.750	4.3.1.24	NA
9	0.060	1tj7A	0.436	4.04	0.055	0.582	4.3.2.1	121,127
10	0.060	2o6yA	0.438	5.08	0.083	0.651	4.3.1.-	NA
11	0.060	1yfmA	0.450	4.40	0.051	0.616	4.2.1.2	NA
12	0.060	1i0aA	0.447	4.08	0.045	0.595	4.3.2.1	NA
13	0.060	3b8eA	0.384	5.78	0.037	0.664	3.6.3.9	NA
14	0.060	1dcnB	0.435	4.03	0.050	0.586	4.3.2.1	NA
15	0.060	2pfmA	0.442	4.20	0.045	0.591	4.3.2.2	127
16	0.060	1mo7A	0.190	5.84	0.036	0.323	3.6.3.9	NA
17	0.060	1yfeA	0.444	4.50	0.067	0.629	4.2.1.2	121,127
18	0.060	1jswB	0.427	4.68	0.060	0.612	4.3.1.1	121,127
19	0.060	3b8eC	0.425	5.85	0.031	0.733	3.6.3.9	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.29	0.702	1.56	0.25	0.75	4kxrB	GO:0005576 GO:0009405 GO:0009986
1	0.17	0.598	4.27	0.08	0.84	3g9gA	GO:0000144 GO:0000147 GO:0001400 GO:0004857 GO:0005934 GO:0005935 GO:0006897 GO:0007049 GO:0032185 GO:0042802 GO:0043086 GO:0061645
2	0.17	0.628	4.34	0.05	0.88	4nqiD	GO:0000281 GO:0000331 GO:0001891 GO:0005885 GO:0005905 GO:0006909 GO:0007009 GO:0009992 GO:0010324 GO:0031150 GO:0035091 GO:0042803 GO:0045335 GO:0046847 GO:0071476 GO:0072583
3	0.16	0.532	5.47	0.05	0.88	3syvC	GO:0005654 GO:0005737 GO:0005768 GO:0005802 GO:0005886 GO:0006897 GO:0008092 GO:0008289 GO:0016020 GO:0019855 GO:0045806 GO:0051044 GO:0051926 GO:0070062 GO:0097320
4	0.16	0.614	4.85	0.05	0.92	4dylA	GO:0000166 GO:0001578 GO:0004672 GO:0004713 GO:0004715 GO:0005524 GO:0005737 GO:0005794 GO:0005829 GO:0005856 GO:0005886 GO:0005925 GO:0006468 GO:0006935 GO:0007173 GO:0007275 GO:0008017 GO:0008283 GO:0008289 GO:0008360 GO:0010976 GO:0015630 GO:0016020 GO:0016023 GO:0016301 GO:0016310 GO:0016740 GO:0018108 GO:0030054 GO:0030155 GO:0031116 GO:0031234 GO:0031410 GO:0034987 GO:0035091 GO:0038083 GO:0042127 GO:0043304 GO:0045087 GO:0045595 GO:0045639 GO:0046777 GO:0051297 GO:0060627 GO:2000145 GO:2000251
5	0.16	0.490	5.53	0.07	0.83	4wpeA	GO:0000142 GO:0000144 GO:0000281 GO:0000917 GO:0005737 GO:0005856 GO:0005935 GO:0007049 GO:0007067 GO:0008092 GO:0044697 GO:0051301 GO:0090339
6	0.16	0.519	5.44	0.08	0.85	3i2wB	GO:0000281 GO:0005543 GO:0005768 GO:0005829 GO:0005886 GO:0007053 GO:0007112 GO:0007269 GO:0008289 GO:0030100 GO:0030496 GO:0032154 GO:0036090 GO:0045211 GO:0045887 GO:0048488 GO:0061024 GO:0071212
7	0.15	0.527	5.49	0.05	0.87	3m3wB	GO:0005654 GO:0005737 GO:0005768 GO:0005802 GO:0005886 GO:0006897 GO:0008092 GO:0008289 GO:0016020 GO:0019855 GO:0045806 GO:0051044 GO:0051926 GO:0070062 GO:0097320
8	0.14	0.588	4.89	0.07	0.89	2efkA	GO:0001891 GO:0005086 GO:0005096 GO:0005654 GO:0005737 GO:0005764 GO:0005794 GO:0005802 GO:0005829 GO:0005856 GO:0005886 GO:0005938 GO:0006897 GO:0007154 GO:0007165 GO:0008289 GO:0016020 GO:0016192 GO:0030036 GO:0042802 GO:0042995 GO:0043231 GO:0043547 GO:0048471 GO:0051056 GO:0070062
9	0.13	0.559	5.21	0.06	0.90	4bneA	GO:0005737 GO:0005768 GO:0005769 GO:0005802 GO:0005829 GO:0005856 GO:0005886 GO:0005901 GO:0005925 GO:0006897 GO:0008092 GO:0008289 GO:0016020 GO:0030036 GO:0030054 GO:0030100 GO:0030659 GO:0031410 GO:0032587 GO:0042995 GO:0045806 GO:0055038 GO:0070300 GO:0070836 GO:0097320
10	0.13	0.507	5.74	0.08	0.88	2v0oA	GO:0001786 GO:0005546 GO:0005886 GO:0005905 GO:0006897 GO:0010324 GO:0016020 GO:0030136 GO:0035091 GO:0048268 GO:0072583 GO:0072659
11	0.12	0.623	4.58	0.06	0.92	2eflA	GO:0005086 GO:0005737 GO:0005764 GO:0005802 GO:0005856 GO:0005886 GO:0005905 GO:0005938 GO:0006897 GO:0008289 GO:0016020 GO:0016023 GO:0016192 GO:0031410 GO:0042802 GO:0043547
12	0.11	0.533	5.39	0.05	0.88	3q0kD	GO:0005215 GO:0005654 GO:0005737 GO:0005768 GO:0005769 GO:0005829 GO:0005856 GO:0005886 GO:0005901 GO:0005911 GO:0005913 GO:0005925 GO:0006897 GO:0008092 GO:0008289 GO:0016020 GO:0019898 GO:0030036 GO:0030100 GO:0030659 GO:0031410 GO:0032587 GO:0036010 GO:0042802 GO:0042995 GO:0043231 GO:0045806 GO:0048858 GO:0055038 GO:0070062 GO:0070300 GO:0070836 GO:0072584 GO:0097320 GO:0098609 GO:0098641
13	0.11	0.522	5.30	0.07	0.83	3i2wA	GO:0000281 GO:0005543 GO:0005768 GO:0005829 GO:0005886 GO:0007053 GO:0007112 GO:0007269 GO:0008289 GO:0030100 GO:0030496 GO:0032154 GO:0036090 GO:0045211 GO:0045887 GO:0048488 GO:0061024 GO:0071212
14	0.10	0.529	5.32	0.06	0.86	3syvB	GO:0005654 GO:0005737 GO:0005768 GO:0005802 GO:0005886 GO:0006897 GO:0008092 GO:0008289 GO:0016020 GO:0019855 GO:0045806 GO:0051044 GO:0051926 GO:0070062 GO:0097320
15	0.09	0.515	5.21	0.08	0.82	2d1lA	GO:0001701 GO:0002230 GO:0003779 GO:0003785 GO:0005102 GO:0005737 GO:0005856 GO:0005912 GO:0007009 GO:0007015 GO:0007399 GO:0007517 GO:0010960 GO:0015629 GO:0030036 GO:0030041 GO:0030282 GO:0032233 GO:0034334 GO:0042802 GO:0050680 GO:0051015 GO:0061333 GO:0071498 GO:0072001 GO:0072102 GO:0072160 GO:0098792 GO:2001013
16	0.08	0.630	4.22	0.06	0.90	1y2oA	GO:0001726 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005913 GO:0007009 GO:0007409 GO:0008022 GO:0008093 GO:0008286 GO:0008360 GO:0009617 GO:0014069 GO:0015629 GO:0016020 GO:0016358 GO:0030141 GO:0030165 GO:0030175 GO:0030838 GO:0032956 GO:0038096 GO:0042802 GO:0042995 GO:0043005 GO:0043025 GO:0043197 GO:0048010 GO:0048167 GO:0051017 GO:0051764 GO:0061003 GO:0070062 GO:0070064 GO:0097481 GO:0098609 GO:0098641 GO:2000251
17	0.07	0.615	4.93	0.07	0.96	5c1fA	GO:0001786 GO:0005547 GO:0005737 GO:0005826 GO:0005829 GO:0005856 GO:0007049 GO:0007067 GO:0051301 GO:0070273 GO:1903475
18	0.06	0.328	4.40	0.05	0.47	5chxA	GO:0000146 GO:0000166 GO:0000793 GO:0001725 GO:0002026 GO:0002027 GO:0003009 GO:0003677 GO:0003774 GO:0003779 GO:0005516 GO:0005524 GO:0005634 GO:0005654 GO:0005737 GO:0005813 GO:0005829 GO:0005859 GO:0005958 GO:0006281 GO:0006302 GO:0006303 GO:0006310 GO:0006936 GO:0006941 GO:0006974 GO:0007512 GO:0008022 GO:0010165 GO:0014728 GO:0014883 GO:0016459 GO:0016874 GO:0016887 GO:0016925 GO:0030016 GO:0030017 GO:0030018 GO:0030049 GO:0030054 GO:0030898 GO:0031449 GO:0032807 GO:0032982 GO:0042803 GO:0046034 GO:0046982 GO:0051103 GO:0051351 GO:0055010 GO:0060048 GO:0070419 GO:0071285 GO:0075713

Consensus prediction of GO terms

Molecular Function	GO:0030234	GO:0046983	GO:0008200	GO:0005246	GO:0015631	GO:0032559	GO:0035639	GO:0004672	GO:0005102	GO:0032550	GO:0035091
GO-Score	0.34	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.30
Biological Processes	GO:0051704	GO:0050790	GO:0044092	GO:0044396	GO:0030866	GO:0061640	GO:0044802	GO:0006884	GO:0055082	GO:0030104	GO:0006898	GO:0071470	GO:1903047	GO:0030031	GO:0006971	GO:0010256	GO:0031154	GO:0051043	GO:0030100	GO:0045732	GO:0031331	GO:0043271	GO:0051924	GO:0045862	GO:0051129	GO:0038127	GO:0033006	GO:0031113	GO:0032386	GO:0042221	GO:0031112	GO:0002886	GO:0045666	GO:2000249	GO:0022604	GO:0010975	GO:0051270	GO:0018108	GO:0042330	GO:0043300	GO:0006952	GO:0032273	GO:0031346	GO:0031023	GO:0008283	GO:0040012	GO:0046777	GO:1903708	GO:0043303	GO:0045637	GO:0048870	GO:0007155
GO-Score	0.57	0.34	0.34	0.34	0.34	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33
Cellular Component	GO:0005940	GO:0005937	GO:0032161	GO:0044463	GO:0000399	GO:0005773	GO:0015629	GO:0030139	GO:0043234	GO:0098589	GO:1903561	GO:0098791	GO:0031981	GO:0005924	GO:0009898	GO:0019897
GO-Score	0.34	0.34	0.34	0.34	0.34	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33	0.33

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv3426

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]