I-TASSER results

Input Sequence in FASTA format

>protein (176 residues)
MHPMIPAEYISNIIYEGPGADSLFFASGQLRELAYSVETTAESLEDELDELDENWKGSSS
DLLADAVERYLQWLSKHSSQLKHAAWVINGLANAYNDTRRKVVPPEEIAANREERRRLIA
SNVAGVNTPAIADLDAQYDQYRARNVAVMNAYVSWTRSALSDLPRWREPPQIYRGG

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 \| \| \| \| \| \| \| \| MHPMIPAEYISNIIYEGPGADSLFFASGQLRELAYSVETTAESLEDELDELDENWKGSSSDLLADAVERYLQWLSKHSSQLKHAAWVINGLANAYNDTRRKVVPPEEIAANREERRRLIASNVAGVNTPAIADLDAQYDQYRARNVAVMNAYVSWTRSALSDLPRWREPPQIYRGG
Prediction	CCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
Conf.Score	98889856666555579995899999999999999999999999999999867787789999999999999999999999999999999999999999996999688888999999999977676647999999999999999999999999888888877588899999889999
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 \| \| \| \| \| \| \| \| MHPMIPAEYISNIIYEGPGADSLFFASGQLRELAYSVETTAESLEDELDELDENWKGSSSDLLADAVERYLQWLSKHSSQLKHAAWVINGLANAYNDTRRKVVPPEEIAANREERRRLIASNVAGVNTPAIADLDAQYDQYRARNVAVMNAYVSWTRSALSDLPRWREPPQIYRGG
Prediction	73343221201020332223210330032034104412310321331012034413321022014204412420241044044213304210213330333224344034124211312222133121231242344244244311310331232123234434534433654688
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160

                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
MHPMIPAEYISNIIYEGPGADSLFFASGQLRELAYSVETTAESLEDELDELDENWKGSSSDLLADAVERYLQWLSKHSSQLKHAAWVINGLANAYNDTRRKVVPPEEIAANREERRRLIASNVAGVNTPAIADLDAQYDQYRARNVAVMNAYVSWTRSALSDLPRWREPPQIYRGG

2g38B

0.33

0.32

0.98

2.86

MUSTER

AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLMDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLRVSDALSKLTPWKAPPPIA---

2g38B

0.33

0.32

0.98

2.60

dPPAS

AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLMDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLRVSDALSKLTPWKAPPPIA---

2g38B

0.33

0.32

0.98

4.08

wdPPAS

AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLMDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLRVSDALSKLTPWKAPPPIA---

2g38B

0.33

0.32

0.98

3.43

wMUSTER

-FEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLMDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLRVSDALSKLTPWKAPPPIA---

2g38B

0.33

0.32

0.98

5.56

wPPAS

AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLMDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLRVSDALSKLTPWKAPPPIA---

2g38B

0.33

0.32

0.98

5.32

dPPAS2

AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLMDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLRVSDALSKLTPWKAPPPIA---

2g38B

0.33

0.32

0.98

4.40

PPAS

AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLMDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLRVSDALSKLTPWKAPPPIA---

2g38B

0.33

0.32

0.98

7.54

Env-PPAS

AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSLMDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLRVSDALSKLTPWKAPPPIA---

4ke2A

0.13

1.00

0.86

MUSTER

IDPAARAAAAAAASKAAVTAADAAAAAATIAASAASVAAATAADDAAASIATINAASAAAKSIAAAAAMAAKDTAAAAASAAAAAVASAAKALEVKAAYAAATTANTAAAAAAATATTAAAAAAAKATIDNAAAAKAAAVATAVSDAAATAATAAAVAAATLEAAAAKAAATAVSA

4ke2A

0.10

0.98

0.85

dPPAS

--MNIDPAARAAAAAAASKAAVTAADAAAAAATIAASAASVAAATAADDAAASI--ATINAASAAAKSIAAAAAMAAKDTAAAAASAAAAAVASAAKALETINVKAAYAAATTANTAAAAAAATATTAAAAAAAKATIDNAAAAKAAAVATAVSDAAATAATAAAVAAATLEAAAA

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=1.26

Estimated TM-score = 0.89±0.07

Estimated RMSD = 2.6±2.0Å

Download Model 2

C-score=-2.41

Download Model 3

C-score=-2.32

Download Model 4

C-score=-2.87

Download Model 5

C-score=-3.98

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	2g38B	0.960	0.80	0.329	0.983
2	4xwpA	0.756	2.04	0.145	0.852
3	4wpeA	0.712	3.33	0.071	0.938
4	4e40A	0.708	3.39	0.051	0.926
5	2d4cB	0.699	3.52	0.058	0.960
6	4nqiA	0.691	3.68	0.098	0.955
7	4iw0A	0.691	3.40	0.082	0.949
8	5ebzA	0.680	3.83	0.047	0.960
9	4dylA1	0.678	3.69	0.054	0.943
10	3ok8A	0.672	3.93	0.075	0.960

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.07	2	2g381	III	Rep, Mult	2,13,14,16,17,18,19,22,23,26,29,30,32,33,36,37,39,40,43,44,47,51,55,63,70,73,81,84,88,95,152,153,156,160,163,164,166,167,169,170,172
2	0.06	2	4n7kL	LDA	Rep, Mult	29,30,88
3	0.06	2	1i4d0	III	Rep, Mult	19,22,25,29,32,33,39,40,43,76,77,80,84,141,145,146,149,150,152,153,157,160,161
4	0.06	2	3r2lA	FE	Rep, Mult	37,74,77
5	0.06	2	1hjbA	NUC	Rep, Mult	69,70,73,74,76,77,80
6	0.06	2	4ll7A	DY	Rep, Mult	112,115
7	0.04	1	2g38B	MN	Rep, Mult	147,150,151
8	0.03	1	1y66B	DIO	Rep, Mult	149,152,156
9	0.03	1	3nozX	PLL	Rep, Mult	48,64,68,71
10	0.03	1	2vs0B	ZN	Rep, Mult	35,82
11	0.03	1	4zzbA	XE	Rep, Mult	108,138,141,142
12	0.03	1	2gdcA	III	Rep, Mult	11,17,20,22,23,26,29,81,152

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	1f1oA	0.473	3.41	0.056	0.619	4.3.2.2	NA
2	0.060	2np0A	0.454	5.11	0.100	0.784	3.4.24.69	NA
3	0.060	2o6yA	0.480	4.32	0.042	0.693	4.3.1.-	NA
4	0.060	3g61A	0.568	4.72	0.029	0.875	3.6.3.44	NA
5	0.060	1j3uA	0.532	3.93	0.046	0.744	4.3.1.1	NA
6	0.060	3btaA	0.520	4.50	0.054	0.812	3.4.24.69	107
7	0.060	3i9wA	0.615	3.58	0.023	0.847	2.7.13.3	31,33,78
8	0.060	1jswB	0.492	3.63	0.048	0.670	4.3.1.1	NA
9	0.060	2dq3A	0.480	3.39	0.078	0.653	6.1.1.11	NA
10	0.060	2pfdB	0.487	3.47	0.054	0.648	2.1.2.5,4.3.1.4	62
11	0.060	2fenD	0.505	3.68	0.069	0.682	5.5.1.2	NA
12	0.060	2pfmA	0.484	3.61	0.042	0.642	4.3.2.2	NA
13	0.060	1c3cA	0.491	3.73	0.042	0.648	4.3.2.2	NA
14	0.060	1k7wD	0.491	3.71	0.076	0.659	4.3.2.1	41
15	0.060	1i0aA	0.448	3.92	0.080	0.636	4.3.2.1	NA
16	0.060	1z0hB	0.247	5.80	0.008	0.455	3.4.24.69	NA
17	0.060	1y2mB	0.475	4.27	0.056	0.733	4.3.1.24	NA
18	0.060	1mhsA	0.483	4.81	0.082	0.744	3.6.3.6	NA
19	0.060	1eulA	0.457	4.98	0.020	0.733	3.6.3.8	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.43	0.919	1.39	0.33	0.98	4kxrB	GO:0005576 GO:0009405 GO:0009986
1	0.23	0.762	2.29	0.15	0.89	3j83A	GO:0005576 GO:0009405 GO:0044315
2	0.23	0.567	4.89	0.06	0.94	4wpeA	GO:0000142 GO:0000144 GO:0000281 GO:0000917 GO:0005737 GO:0005856 GO:0005935 GO:0007049 GO:0007067 GO:0008092 GO:0044697 GO:0051301 GO:0090339
3	0.19	0.705	3.56	0.10	0.98	4nqiD	GO:0000281 GO:0000331 GO:0001891 GO:0005885 GO:0005905 GO:0006909 GO:0007009 GO:0009992 GO:0010324 GO:0031150 GO:0035091 GO:0042803 GO:0045335 GO:0046847 GO:0071476 GO:0072583
4	0.19	0.620	4.28	0.09	0.97	2d1lA	GO:0001701 GO:0002230 GO:0003779 GO:0003785 GO:0005102 GO:0005737 GO:0005856 GO:0005912 GO:0007009 GO:0007015 GO:0007399 GO:0007517 GO:0010960 GO:0015629 GO:0030036 GO:0030041 GO:0030282 GO:0032233 GO:0034334 GO:0042802 GO:0050680 GO:0051015 GO:0061333 GO:0071498 GO:0072001 GO:0072102 GO:0072160 GO:0098792 GO:2001013
5	0.19	0.718	3.36	0.09	0.96	1y2oA	GO:0001726 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005913 GO:0007009 GO:0007409 GO:0008022 GO:0008093 GO:0008286 GO:0008360 GO:0009617 GO:0014069 GO:0015629 GO:0016020 GO:0016358 GO:0030141 GO:0030165 GO:0030175 GO:0030838 GO:0032956 GO:0038096 GO:0042802 GO:0042995 GO:0043005 GO:0043025 GO:0043197 GO:0048010 GO:0048167 GO:0051017 GO:0051764 GO:0061003 GO:0070062 GO:0070064 GO:0097481 GO:0098609 GO:0098641 GO:2000251
6	0.15	0.763	1.92	0.14	0.86	4xxxA	GO:0005576 GO:0009405 GO:0044315
7	0.13	0.690	3.53	0.08	0.94	5jdoA	GO:0016020 GO:0016021
8	0.10	0.699	3.52	0.06	0.96	2d4cB	GO:0000139 GO:0002090 GO:0005737 GO:0005829 GO:0005886 GO:0006897 GO:0007018 GO:0007165 GO:0007417 GO:0008289 GO:0016020 GO:0019886 GO:0030669 GO:0042059 GO:0042802 GO:0048488 GO:0070062
9	0.10	0.523	4.81	0.08	0.89	5c1fA	GO:0001786 GO:0005547 GO:0005737 GO:0005826 GO:0005829 GO:0005856 GO:0007049 GO:0007067 GO:0051301 GO:0070273 GO:1903475
10	0.09	0.542	4.93	0.07	0.94	2z0vA	GO:0005737 GO:0005768 GO:0005769 GO:0006897 GO:0007165 GO:0007417 GO:0008289 GO:0016020 GO:0031901 GO:0042802 GO:0070062
11	0.09	0.691	3.40	0.08	0.95	4iw0A	GO:0000166 GO:0002218 GO:0002376 GO:0003676 GO:0004672 GO:0004674 GO:0005524 GO:0005737 GO:0005829 GO:0006468 GO:0006954 GO:0007249 GO:0009615 GO:0010008 GO:0010629 GO:0016032 GO:0016301 GO:0016310 GO:0016740 GO:0018105 GO:0032480 GO:0032481 GO:0032606 GO:0032727 GO:0032728 GO:0033138 GO:0035666 GO:0043123 GO:0044565 GO:0045087 GO:0045359 GO:0045944 GO:0050830 GO:0051219 GO:0051607 GO:1901214 GO:1904417
12	0.09	0.659	4.24	0.09	0.98	4iwoA	GO:0000166 GO:0002218 GO:0002376 GO:0003676 GO:0004672 GO:0004674 GO:0005524 GO:0005737 GO:0005829 GO:0006468 GO:0006954 GO:0007249 GO:0009615 GO:0010008 GO:0010629 GO:0016032 GO:0016301 GO:0016310 GO:0016740 GO:0018105 GO:0032480 GO:0032481 GO:0032606 GO:0032727 GO:0032728 GO:0033138 GO:0035666 GO:0043123 GO:0044565 GO:0045087 GO:0045359 GO:0045944 GO:0050830 GO:0051219 GO:0051607 GO:1901214 GO:1904417
13	0.08	0.649	3.76	0.09	0.92	4kikB	GO:0000166 GO:0002223 GO:0003009 GO:0004672 GO:0004674 GO:0005524 GO:0005634 GO:0005737 GO:0005829 GO:0006468 GO:0006954 GO:0007249 GO:0007252 GO:0008284 GO:0008384 GO:0008385 GO:0009615 GO:0009636 GO:0009898 GO:0010803 GO:0010976 GO:0016020 GO:0016301 GO:0016310 GO:0016740 GO:0019901 GO:0030866 GO:0031175 GO:0032496 GO:0033209 GO:0035509 GO:0035631 GO:0035666 GO:0038095 GO:0042325 GO:0042493 GO:0042501 GO:0042803 GO:0043066 GO:0043123 GO:0043231 GO:0045087 GO:0045121 GO:0045893 GO:0045944 GO:0046982 GO:0050852 GO:0051092 GO:0051403 GO:0070423 GO:0070498 GO:0070542 GO:0071356 GO:0090002 GO:0097110 GO:1901216 GO:1903140 GO:1903347
14	0.07	0.602	4.33	0.07	0.89	3qa8A	GO:0004672 GO:0005524 GO:0005622 GO:0006468 GO:0007252 GO:0008384
15	0.07	0.498	4.24	0.09	0.74	3qa8G	GO:0004672 GO:0005524 GO:0005622 GO:0006468 GO:0007252 GO:0008384
16	0.06	0.425	4.52	0.03	0.64	3hztA	GO:0000166 GO:0004672 GO:0004674 GO:0005509 GO:0005524 GO:0006468 GO:0016301 GO:0016310 GO:0046872
17	0.06	0.351	5.57	0.04	0.63	4btfA	GO:0000166 GO:0004672 GO:0005524 GO:0005737 GO:0005886 GO:0006468 GO:0012501 GO:0016020 GO:0019901 GO:0032403 GO:0070207 GO:0070266
18	0.06	0.342	4.91	0.06	0.55	4d9uA	GO:0000166 GO:0000287 GO:0001501 GO:0002224 GO:0004672 GO:0004674 GO:0005524 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0006468 GO:0006915 GO:0007049 GO:0007165 GO:0007417 GO:0016301 GO:0016310 GO:0016740 GO:0019901 GO:0030307 GO:0032496 GO:0035556 GO:0043027 GO:0043066 GO:0043154 GO:0043555 GO:0043620 GO:0045597 GO:0045944 GO:0046872

Consensus prediction of GO terms

Molecular Function	GO:0042802	GO:0005543	GO:0046983	GO:0032403
GO-Score	0.39	0.39	0.39	0.38
Biological Processes	GO:0009405	GO:0009306	GO:0071806	GO:1902410	GO:0000280	GO:0090337	GO:0032232	GO:0090529	GO:0055082	GO:0006971	GO:0031154	GO:0030031	GO:0030104	GO:0006884	GO:0006898	GO:0071470	GO:0016236	GO:0043009	GO:0072080	GO:0051495	GO:0061333	GO:0032835	GO:0072507	GO:0034331	GO:0031214	GO:0050678	GO:0034332	GO:0061061	GO:0034405	GO:0008154	GO:0001503	GO:0035850	GO:0008285	GO:0050691	GO:0051258	GO:0044089	GO:0055065	GO:0007009
GO-Score	0.57	0.46	0.46	0.46	0.46	0.46	0.46	0.46	0.39	0.39	0.39	0.39	0.39	0.39	0.39	0.39	0.38	0.38	0.38	0.38	0.38	0.38	0.38	0.38	0.38	0.38	0.38	0.38	0.38	0.38	0.38	0.38	0.38	0.38	0.38	0.38	0.38	0.34
Cellular Component	GO:0005576	GO:0032161	GO:0043234	GO:0005826	GO:0000399	GO:0005940	GO:0009986	GO:0098589	GO:0005773	GO:0044459	GO:0012505	GO:0030139	GO:0070161
GO-Score	0.57	0.46	0.46	0.46	0.46	0.46	0.43	0.39	0.39	0.39	0.39	0.39	0.38

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv3425

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]