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I-TASSER results for job id Rv3335c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

 Input Sequence in FASTA format
 Predicted Secondary Structure
 Predicted Solvent Accessibility
 Predicted Normalized B-facotr
 Top 10 threading templates used by I-TASSER
 Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)
 Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)
 Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)
  Ligand binding sites

Rank C-score Cluster
size		 PDB
Hit		 Lig
Name		 Download
Complex		 Ligand Binding Site Residues
10.09 4 2ycwA 2CV Rep, Mult 203,206,228,229,230,233,237
20.05 2 3pyrI MG Rep, Mult 91,94
30.05 2 2w0fC HX0 Rep, Mult 234,235,265,269
40.05 2 4or2B FM9 Rep, Mult 97,109,113,187,192,195,196,199,203,233,236,237,240,244,251,252,255,258,262
50.05 2 2y01B 2CV Rep, Mult 55,283
60.05 2 3sjqC PHU Rep, Mult 39,42
70.02 1 2y03A Y01 Rep, Mult 114,117,153,154,157
80.02 1 2ycxB SOG Rep, Mult 121,125,157,198
90.02 1 2h2sA SEK Rep, Mult 243,245,267
100.02 1 2y00B Y01 Rep, Mult 78,82,85,144,148,151,155
110.02 1 2y00A 2CV Rep, Mult 252,257,261
120.02 1 2y03B Y01 Rep, Mult 200,204,205,208
130.02 1 2y03B Y01 Rep, Mult 122,125,143,146,147,150
140.02 1 2y04B 2CV Rep, Mult 54,55

Download the all possible binding ligands and detailed prediction summary.
Download the templates clustering results.
(a)C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)Cluster size is the total number of templates in a cluster.
(c)Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column.
Mult is the complex structures with all potential binding ligands in the cluster.

  Enzyme Commission (EC) numbers and active sites

RankCscoreECPDB
Hit		TM-scoreRMSDaIDENaCovEC NumberActive Site Residues
10.0601qleA0.4705.200.0450.6781.9.3.1NA
20.0601tj7A0.4494.800.0680.6194.3.2.1NA
30.0601b8fA0.4405.670.0420.6894.3.1.3NA
40.0602wpnB0.4305.650.0500.6501.12.7.2NA
50.0601w27A0.4375.950.0520.7094.3.1.24NA
60.0601vdkA0.4425.440.0710.6504.2.1.2NA
70.0602occN0.4734.900.0490.6541.9.3.1232,265
80.0601yisA0.4334.810.0460.6234.3.2.2NA
90.0603d4sA0.6304.200.1090.8343.2.1.1783,202,229
100.0601yfmA0.4425.230.0760.6544.2.1.2NA
110.0603gtdA0.4495.130.0770.6404.2.1.2NA
120.0603gzhA0.4385.210.0610.6504.3.2.2238
130.0601eulA0.4546.340.0580.7823.6.3.8NA
140.0601yfeA0.4355.360.0630.6404.2.1.2NA
150.0603no9A0.4365.380.0830.6544.2.1.262,86,274
160.0602frvD0.4345.740.0600.6711.12.2.185,94
170.0601fftA0.5045.900.0990.8131.10.3.-NA
180.0601mo7A0.2395.870.0810.3883.6.3.9NA
190.0601jswB0.4684.800.0680.6544.3.1.1NA

(a)CscoreEC is the confidence score for the EC number prediction. CscoreEC values range in between [0-1];
where a higher score indicates a more reliable EC number prediction.
(b)TM-score is a measure of global structural similarity between query and template protein.
(c)RMSDa is the RMSD between residues that are structurally aligned by TM-align.
(d)IDENa is the percentage sequence identity in the structurally aligned region.
(e)Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided
by length of the query protein.

  Gene Ontology (GO) terms

Homologous GO templates in PDB 
RankCscoreGOTM-scoreRMSDaIDENaCovPDB HitAssociated GO Terms
00.240.6264.030.120.823oduA GO:0000187 GO:0001618 GO:0001666 GO:0001764 GO:0002064 GO:0002407 GO:0003779 GO:0004871 GO:0004930 GO:0004950 GO:0005737 GO:0005764 GO:0005768 GO:0005769 GO:0005770 GO:0005886 GO:0006915 GO:0006935 GO:0006954 GO:0007165 GO:0007186 GO:0007204 GO:0008038 GO:0008144 GO:0009615 GO:0009986 GO:0015026 GO:0016020 GO:0016021 GO:0016023 GO:0016032 GO:0016477 GO:0016494 GO:0019064 GO:0019722 GO:0019955 GO:0022029 GO:0030054 GO:0030260 GO:0030334 GO:0031252 GO:0031410 GO:0031625 GO:0032027 GO:0043067 GO:0043130 GO:0043217 GO:0048714 GO:0050920 GO:0051924 GO:0060048 GO:0070062 GO:0070098 GO:0071345
10.240.7422.950.070.855cgcA GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0005737 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0007205 GO:0007206 GO:0007216 GO:0007268 GO:0007612 GO:0007626 GO:0008066 GO:0008152 GO:0009253 GO:0014069 GO:0016020 GO:0016021 GO:0016787 GO:0016798 GO:0016998 GO:0019076 GO:0019835 GO:0030430 GO:0042742 GO:0043005 GO:0048169 GO:0050890 GO:0051966 GO:0070062
20.230.6404.120.050.834grvA GO:0001659 GO:0003085 GO:0003254 GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0005737 GO:0005739 GO:0005783 GO:0005794 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0007218 GO:0007612 GO:0008152 GO:0008344 GO:0009253 GO:0009898 GO:0009986 GO:0014049 GO:0014054 GO:0016020 GO:0016021 GO:0016492 GO:0016787 GO:0016798 GO:0016998 GO:0019076 GO:0019835 GO:0030424 GO:0030425 GO:0030430 GO:0032280 GO:0033993 GO:0042742 GO:0042803 GO:0043025 GO:0043065 GO:0043066 GO:0043195 GO:0043197 GO:0043198 GO:0043204 GO:0043576 GO:0043679 GO:0044309 GO:0045121 GO:0045202 GO:0046982 GO:0047485 GO:0050965 GO:0051280 GO:0051281 GO:0051930 GO:0060732 GO:0070779 GO:0071545 GO:0090238 GO:0097151 GO:0098900 GO:1990123 GO:2001259
30.220.7582.700.060.864or2B GO:0000186 GO:0000187 GO:0004871 GO:0004930 GO:0005506 GO:0005634 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0007205 GO:0007216 GO:0007268 GO:0007626 GO:0008066 GO:0009055 GO:0014069 GO:0016020 GO:0016021 GO:0019233 GO:0020037 GO:0022900 GO:0030425 GO:0038037 GO:0038038 GO:0038042 GO:0042597 GO:0043005 GO:0043408 GO:0046872 GO:0051482 GO:0051930 GO:0051966 GO:0055114 GO:0071257
40.200.6604.050.050.854xesA GO:0001659 GO:0003085 GO:0003254 GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0005737 GO:0005739 GO:0005783 GO:0005794 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0007218 GO:0007612 GO:0008152 GO:0008344 GO:0009253 GO:0009898 GO:0009986 GO:0014049 GO:0014054 GO:0016020 GO:0016021 GO:0016492 GO:0016787 GO:0016798 GO:0016998 GO:0019076 GO:0019835 GO:0030424 GO:0030425 GO:0030430 GO:0032280 GO:0033993 GO:0042742 GO:0042803 GO:0043025 GO:0043065 GO:0043066 GO:0043195 GO:0043197 GO:0043198 GO:0043204 GO:0043576 GO:0043679 GO:0044309 GO:0045121 GO:0045202 GO:0046982 GO:0047485 GO:0050965 GO:0051280 GO:0051281 GO:0051930 GO:0060732 GO:0070779 GO:0071545 GO:0090238 GO:0097151 GO:0098900 GO:1990123 GO:2001259
50.180.6503.870.060.844l6rA GO:0004871 GO:0004888 GO:0004930 GO:0004967 GO:0005085 GO:0005506 GO:0005768 GO:0005886 GO:0005887 GO:0006091 GO:0006887 GO:0007165 GO:0007166 GO:0007186 GO:0007188 GO:0007189 GO:0007584 GO:0008217 GO:0009055 GO:0009755 GO:0016020 GO:0016021 GO:0017046 GO:0020037 GO:0022900 GO:0042593 GO:0042594 GO:0042597 GO:0043547 GO:0046872 GO:0055114 GO:0070873 GO:0071377
60.160.6503.690.040.824pxzA GO:0001609 GO:0001621 GO:0001973 GO:0004871 GO:0004930 GO:0005085 GO:0005506 GO:0005622 GO:0005739 GO:0005886 GO:0005887 GO:0005901 GO:0006930 GO:0007165 GO:0007186 GO:0007188 GO:0007193 GO:0007596 GO:0007599 GO:0008347 GO:0009055 GO:0009897 GO:0009925 GO:0009986 GO:0010700 GO:0016020 GO:0016021 GO:0020037 GO:0022900 GO:0030030 GO:0030168 GO:0031224 GO:0035589 GO:0042597 GO:0043270 GO:0043491 GO:0043547 GO:0045028 GO:0045596 GO:0046872 GO:0051924 GO:0055114 GO:0070527 GO:0070588 GO:0071318 GO:0071407 GO:0071805 GO:1904139
70.160.6404.090.100.844n6hA GO:0000060 GO:0004871 GO:0004930 GO:0004985 GO:0005506 GO:0005737 GO:0005886 GO:0005887 GO:0006955 GO:0007165 GO:0007186 GO:0007187 GO:0007193 GO:0007200 GO:0007218 GO:0007268 GO:0008344 GO:0009055 GO:0010629 GO:0016020 GO:0016021 GO:0019233 GO:0020037 GO:0022900 GO:0031226 GO:0031982 GO:0032460 GO:0032590 GO:0032793 GO:0033138 GO:0038003 GO:0038046 GO:0042597 GO:0042755 GO:0042923 GO:0043005 GO:0043679 GO:0045121 GO:0045211 GO:0046872 GO:0051881 GO:0051924 GO:0051930 GO:0055114 GO:0071363 GO:0071456 GO:0097237
80.160.6423.990.060.844ib4A GO:0001755 GO:0001819 GO:0001938 GO:0001965 GO:0002031 GO:0003007 GO:0003300 GO:0004871 GO:0004930 GO:0004993 GO:0005096 GO:0005506 GO:0005737 GO:0005886 GO:0005887 GO:0006182 GO:0006874 GO:0006939 GO:0007165 GO:0007186 GO:0007202 GO:0007205 GO:0007210 GO:0007507 GO:0007610 GO:0008144 GO:0008284 GO:0009055 GO:0010507 GO:0010513 GO:0014033 GO:0014065 GO:0014827 GO:0016020 GO:0016021 GO:0016310 GO:0019722 GO:0020037 GO:0022900 GO:0030054 GO:0030425 GO:0034220 GO:0035733 GO:0042310 GO:0042493 GO:0042597 GO:0043005 GO:0043025 GO:0043066 GO:0043123 GO:0043406 GO:0043547 GO:0043647 GO:0045202 GO:0046872 GO:0048598 GO:0050715 GO:0050795 GO:0051000 GO:0051209 GO:0051378 GO:0051781 GO:0055114 GO:0060548 GO:0070371 GO:0070374 GO:0070528 GO:0071418 GO:0071502 GO:1904015
90.150.6523.920.080.845dsgB GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0005085 GO:0005737 GO:0005886 GO:0005887 GO:0007165 GO:0007166 GO:0007186 GO:0007197 GO:0007207 GO:0007213 GO:0007271 GO:0008152 GO:0008283 GO:0009253 GO:0010033 GO:0014069 GO:0016020 GO:0016021 GO:0016787 GO:0016798 GO:0016907 GO:0016998 GO:0019076 GO:0019835 GO:0030054 GO:0030430 GO:0032279 GO:0040012 GO:0042383 GO:0042742 GO:0043025 GO:0043547 GO:0043679 GO:0045202 GO:0045211
100.140.6573.800.060.844yayA GO:0001558 GO:0001596 GO:0001822 GO:0002018 GO:0002034 GO:0003081 GO:0004871 GO:0004930 GO:0004945 GO:0005506 GO:0005622 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0007200 GO:0007204 GO:0007266 GO:0009055 GO:0010744 GO:0010873 GO:0016020 GO:0016021 GO:0019229 GO:0019722 GO:0020037 GO:0022900 GO:0031711 GO:0032270 GO:0032430 GO:0033864 GO:0034374 GO:0035813 GO:0038166 GO:0042127 GO:0042312 GO:0042597 GO:0046872 GO:0046982 GO:0050727 GO:0050729 GO:0051482 GO:0055114 GO:0060326 GO:0086097 GO:2000379
110.120.6433.840.060.834u15B GO:0003056 GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0005886 GO:0005887 GO:0006939 GO:0007165 GO:0007186 GO:0007197 GO:0007207 GO:0007213 GO:0007271 GO:0007586 GO:0008144 GO:0008152 GO:0009253 GO:0016020 GO:0016021 GO:0016323 GO:0016787 GO:0016798 GO:0016907 GO:0016998 GO:0019229 GO:0019835 GO:0030054 GO:0030425 GO:0032279 GO:0042166 GO:0042742 GO:0043679 GO:0045202 GO:0045211 GO:0045987 GO:0046541
120.080.6333.660.080.813rzeA GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0004969 GO:0005654 GO:0005737 GO:0005886 GO:0005887 GO:0006954 GO:0007165 GO:0007186 GO:0007200 GO:0007613 GO:0008152 GO:0008542 GO:0009253 GO:0016020 GO:0016021 GO:0016787 GO:0016798 GO:0016998 GO:0019076 GO:0019229 GO:0019835 GO:0030430 GO:0032962 GO:0042742 GO:0043114 GO:0045907 GO:0048016 GO:0048167 GO:0048245 GO:0050804 GO:0071420
130.080.6394.010.100.834iarA GO:0002031 GO:0004871 GO:0004930 GO:0004993 GO:0005506 GO:0005737 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0007187 GO:0007198 GO:0007205 GO:0007268 GO:0007610 GO:0007631 GO:0008144 GO:0009055 GO:0014059 GO:0014063 GO:0016020 GO:0016021 GO:0020037 GO:0022900 GO:0030818 GO:0032229 GO:0035690 GO:0042220 GO:0042310 GO:0042493 GO:0042597 GO:0042756 GO:0045471 GO:0046849 GO:0046872 GO:0050795 GO:0051378 GO:0051385 GO:0051967 GO:0055114 GO:0071312 GO:0071502
140.080.6523.790.060.835ee7A GO:0003796 GO:0003824 GO:0004871 GO:0004888 GO:0004930 GO:0004967 GO:0005085 GO:0005768 GO:0005886 GO:0005887 GO:0006091 GO:0006887 GO:0007165 GO:0007166 GO:0007186 GO:0007188 GO:0007189 GO:0007584 GO:0008152 GO:0008217 GO:0009253 GO:0009755 GO:0016020 GO:0016021 GO:0016787 GO:0016798 GO:0016998 GO:0017046 GO:0019076 GO:0019835 GO:0030430 GO:0042593 GO:0042594 GO:0042742 GO:0043547 GO:0070873 GO:0071377
150.080.6473.940.090.833emlA GO:0001609 GO:0001973 GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0005886 GO:0005887 GO:0006171 GO:0006909 GO:0006915 GO:0006954 GO:0006968 GO:0007165 GO:0007186 GO:0007188 GO:0007267 GO:0007417 GO:0007596 GO:0007600 GO:0008015 GO:0008152 GO:0009253 GO:0010579 GO:0016020 GO:0016021 GO:0016787 GO:0016798 GO:0016998 GO:0019076 GO:0019835 GO:0019899 GO:0030430 GO:0042742 GO:0042802 GO:0044267
160.080.6284.170.080.834dklA GO:0001965 GO:0002438 GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0004979 GO:0004985 GO:0005245 GO:0005737 GO:0005829 GO:0005886 GO:0005887 GO:0005925 GO:0007165 GO:0007186 GO:0007191 GO:0007193 GO:0007194 GO:0007200 GO:0007204 GO:0007218 GO:0007268 GO:0007626 GO:0008022 GO:0008152 GO:0009253 GO:0009314 GO:0016020 GO:0016021 GO:0016787 GO:0016798 GO:0016998 GO:0019076 GO:0019233 GO:0019835 GO:0019904 GO:0030425 GO:0030430 GO:0030818 GO:0031005 GO:0031635 GO:0031681 GO:0032094 GO:0032100 GO:0032496 GO:0032590 GO:0032839 GO:0033554 GO:0038003 GO:0038047 GO:0042060 GO:0042220 GO:0042383 GO:0042742 GO:0042755 GO:0042923 GO:0043005 GO:0043204 GO:0043278 GO:0043950 GO:0043951 GO:0044849 GO:0045019 GO:0045121 GO:0045429 GO:0045471 GO:0048149 GO:0050769 GO:0051481 GO:0051930 GO:0060079 GO:0061358 GO:0070374 GO:0070588 GO:0070848 GO:0071315 GO:0098794 GO:2000310
170.080.6314.040.070.824qimA GO:0000122 GO:0001503 GO:0001570 GO:0001649 GO:0001701 GO:0001708 GO:0001755 GO:0001947 GO:0002052 GO:0002053 GO:0003007 GO:0003140 GO:0003323 GO:0004871 GO:0004888 GO:0004930 GO:0005113 GO:0005506 GO:0005737 GO:0005794 GO:0005886 GO:0005901 GO:0005929 GO:0007165 GO:0007166 GO:0007186 GO:0007224 GO:0007228 GO:0007275 GO:0007368 GO:0007371 GO:0007389 GO:0007417 GO:0007494 GO:0008144 GO:0008284 GO:0009055 GO:0009952 GO:0009953 GO:0010468 GO:0010628 GO:0010629 GO:0016020 GO:0016021 GO:0017147 GO:0020037 GO:0021542 GO:0021696 GO:0021794 GO:0021904 GO:0021910 GO:0021938 GO:0021953 GO:0021987 GO:0022900 GO:0030666 GO:0030857 GO:0031069 GO:0034504 GO:0035264 GO:0035567 GO:0040018 GO:0042307 GO:0042475 GO:0042597 GO:0042813 GO:0042995 GO:0043066 GO:0043231 GO:0043392 GO:0045880 GO:0045892 GO:0045893 GO:0045944 GO:0046622 GO:0046872 GO:0048143 GO:0048468 GO:0048565 GO:0048568 GO:0048589 GO:0048741 GO:0048853 GO:0048873 GO:0050679 GO:0050821 GO:0051451 GO:0051799 GO:0055114 GO:0060070 GO:0060170 GO:0060248 GO:0060413 GO:0060644 GO:0060684 GO:0061053 GO:0061113 GO:0070062 GO:0070986 GO:0071397 GO:0072001 GO:0072285 GO:0072372 GO:0090190 GO:0097542 GO:2000036 GO:2000826
180.080.6274.220.090.834djhB GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0004985 GO:0005886 GO:0005887 GO:0006955 GO:0007165 GO:0007186 GO:0007193 GO:0007200 GO:0007218 GO:0007268 GO:0007600 GO:0007610 GO:0007626 GO:0008152 GO:0009253 GO:0009314 GO:0016020 GO:0016021 GO:0016787 GO:0016798 GO:0016998 GO:0019076 GO:0019233 GO:0019835 GO:0030425 GO:0030430 GO:0031635 GO:0032868 GO:0033603 GO:0033685 GO:0038003 GO:0038048 GO:0040017 GO:0042220 GO:0042711 GO:0042742 GO:0042755 GO:0042923 GO:0043005 GO:0043025 GO:0043204 GO:0043278 GO:0043627 GO:0043679 GO:0044849 GO:0045202 GO:0045471 GO:0046877 GO:0048148 GO:0050951 GO:0051607 GO:0051930 GO:0071222 GO:1900745 GO:1901381 GO:1903715 GO:1903937 GO:1990708 GO:2000505


Consensus prediction of GO terms		 
Molecular Function GO:0003796 GO:0044389 GO:0032182 GO:0004950 GO:0017022 GO:0046914 GO:0046906 GO:0008066 GO:0042803 GO:0047485 GO:0046982 GO:0016492
GO-Score 0.53 0.48 0.48 0.48 0.48 0.44 0.44 0.41 0.38 0.38 0.38 0.38
Biological Processes GO:0016998 GO:0042742 GO:0009253 GO:0007612 GO:0019076 GO:0019835 GO:0051930 GO:0006941 GO:0021885 GO:0019932 GO:0036293 GO:0019221 GO:2000145 GO:0032101 GO:0048666 GO:0030855 GO:0008037 GO:0039663 GO:0060047 GO:0048713 GO:0030595 GO:0045687 GO:0042552 GO:0021537 GO:0007009 GO:0036336 GO:0007200 GO:0048168 GO:0006091 GO:0051602 GO:0071214 GO:0000187 GO:0051966 GO:0007216 GO:0007205 GO:1990123 GO:0003254 GO:0043576 GO:0007218 GO:0014049 GO:0051281 GO:0090238 GO:0043066 GO:0014054 GO:0051280 GO:0070779 GO:2001259 GO:0050965 GO:0008344 GO:0001659 GO:0043065 GO:0003085 GO:0071545 GO:0060732 GO:0033993 GO:0098900 GO:0097151
GO-Score 0.53 0.53 0.53 0.53 0.53 0.53 0.52 0.48 0.48 0.48 0.48 0.48 0.48 0.48 0.48 0.48 0.48 0.48 0.48 0.48 0.48 0.48 0.48 0.48 0.48 0.48 0.47 0.47 0.44 0.44 0.44 0.41 0.41 0.41 0.41 0.38 0.38 0.38 0.38 0.38 0.38 0.38 0.38 0.38 0.38 0.38 0.38 0.38 0.38 0.38 0.38 0.38 0.38 0.38 0.38 0.38 0.38
Cellular Component GO:0009986 GO:0030430 GO:0031410 GO:0000323 GO:0038037 GO:0070062 GO:0014069 GO:0045121 GO:0009898 GO:0032280 GO:0043197 GO:0005794 GO:0043204 GO:0005783 GO:0043195 GO:0043198 GO:0005739
GO-Score 0.53 0.53 0.48 0.48 0.44 0.42 0.41 0.38 0.38 0.38 0.38 0.38 0.38 0.38 0.38 0.38 0.38

(a)CscoreGO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)TM-score is a measure of global structural similarity between query and template protein.
(c)RMSDa is the RMSD between residues that are structurally aligned by TM-align.
(d)IDENa is the percentage sequence identity in the structurally aligned region.
(e)Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on CscoreGO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]


Please cite the following articles when you use the I-TASSER server:
1. J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2. J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.