I-TASSER results

Input Sequence in FASTA format

>protein (308 residues)
MTGPPPSLPERIRTDEADVLMLPDGRALAYLEWGDSTGYPAFYFHGTPSSRLEGAFADGA
ARRTGFRLIAIDRPGYGRSTFQAGRNFRDWPADVCALADAFELEEFGVVGHSGAGPHLFA
CGAVIPRTRLAFVGALGPWGPLATPDIMRSLNAADRCYARLARSGPRLFGALFAPLGWCA
KYTPGLFSTLLAAAVPAADKHLLSDERFGRHLRAIQLEAFRQGSRGAAYESFLQFRPWGF
DLAEVAVPTHIWLGDRDSFVPRAMGEYLQRAIPHVDLHWAHGKGHFNIEDWDAILAACAL
DIGKRRGG

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| MTGPPPSLPERIRTDEADVLMLPDGRALAYLEWGDSTGYPAFYFHGTPSSRLEGAFADGAARRTGFRLIAIDRPGYGRSTFQAGRNFRDWPADVCALADAFELEEFGVVGHSGAGPHLFACGAVIPRTRLAFVGALGPWGPLATPDIMRSLNAADRCYARLARSGPRLFGALFAPLGWCAKYTPGLFSTLLAAAVPAADKHLLSDERFGRHLRAIQLEAFRQGSRGAAYESFLQFRPWGFDLAEVAVPTHIWLGDRDSFVPRAMGEYLQRAIPHVDLHWAHGKGHFNIEDWDAILAACALDIGKRRGG
Prediction	CCCCCCCCCCCCCCCCCCEEEHCCCCEEEEEEHCCCCCCEEEEHCCCCCCCCHHHHHHHHHHHHCCEEEEHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEHCCHHHHHHHHHHHCCCCEEEEEEEHCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEEHCCCCCCCHHHHHHHHHHCCCCEEEEHCCCCCCCHHHHHHHHHHHHHHHHHHHCC
Conf.Score	99999988888888888789968985999999789999879998899998556899999999989989995899999999999999999999999999998999879999886799999999987986478999876888887775555566457889998866578899988666544557878999998875555555554678999999999999999867899999999868788876658998799985899878999999999989997999969998875554579999999999997779
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| MTGPPPSLPERIRTDEADVLMLPDGRALAYLEWGDSTGYPAFYFHGTPSSRLEGAFADGAARRTGFRLIAIDRPGYGRSTFQAGRNFRDWPADVCALADAFELEEFGVVGHSGAGPHLFACGAVIPRTRLAFVGALGPWGPLATPDIMRSLNAADRCYARLARSGPRLFGALFAPLGWCAKYTPGLFSTLLAAAVPAADKHLLSDERFGRHLRAIQLEAFRQGSRGAAYESFLQFRPWGFDLAEVAVPTHIWLGDRDSFVPRAMGEYLQRAIPHVDLHWAHGKGHFNIEDWDAILAACALDIGKRRGG
Prediction	87464263454354554320304310200012233771200000000000230042024203714000000000010103444622132003001200421715400000001000000000231343000000000001113234214414223302220143123002211322332242223103311332124234421334202410341133012210200022012103504330550300000000350210216104300610360311202401200122124101300340066478
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCCCCCCCCCCCEEEHCCCCEEEEEEHCCCCCCEEEEHCCCCCCCCHHHHHHHHHHHHCCEEEEHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEHCCHHHHHHHHHHHCCCCEEEEEEEHCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEEHCCCCCCCHHHHHHHHHHCCCCEEEEHCCCCCCCHHHHHHHHHHHHHHHHHHHCC
MTGPPPSLPERIRTDEADVLMLPDGRALAYLEWGDSTGYPAFYFHGTPSSRLEGAFADGAARRTGFRLIAIDRPGYGRSTFQAGRNFRDWPADVCALADAFELEEFGVVGHSGAGPHLFACGAVIPRTRLAFVGALGPWGPLATPDIMRSLNAADRCYARLARSGPRLFGALFAPLGWCAKYTPGLFSTLLAAAVPAADKHLLSDERFGRHLRAIQLEAFRQGSRGAAYESFLQFRPWGFDLAEVAVPTHIWLGDRDSFVPRAMGEYLQRAIPHVDLHWAHGKGHFNIEDWDAILAACALDIGKRRGG

1zoiA

0.17

0.15

0.89

2.24

MUSTER

-----------------SYVTTKDGVQIFYKDWGPRDAPVIHFHHGWPLSADDWDAQLLFFLAHGYRVVAHDRRGHGRSSQVWDHDMDHYADDVAAVVAHLGIQGAVHVGHSTGGGEVVRYMARHPEDKVAKAVLIAAVPPLMVQTPGNPGGLPKSVFDGFQAQVASNRAQFYRDVPAGP-------------FYGYNRPGVEASEGIIGNWWRQGMIGSAKAHYDGIVAFSQT--DFTEDLKGIQQPVLVMHGDDDQIVPYENGVLSAKLLPNGALKTYKGYPHGMPTTHADVINADLLAFIRS---

1zoiA

0.18

0.16

0.89

2.18

dPPAS

-----------------SYVTTKDGVQIFYKDWGPRDAPVIHFHHGWPLSADDWDAQLLFFLAHGYRVVAHDRRGHGRSSVWDGHDMDHYADDVAAVVAHLGIQGAVHVGHSTGGGEVVRYMARHPEDKVAKAVLIAAVPPLMVQTPGNPGGLPKSVFDGFQAQVASNRAQFYRDVPAGPF-------------YGYNRPGVEASEGIIGNWWRQGMIGSAKAHYDGIVAFSQT--DFTEDLKGIQQPVLVMHGDDDQIVPYENGVLSAKLLPNGALKTYKGYPHGMPTTHADVINADLLAFIRS---

1zoiA

0.18

0.16

0.89

2.58

wdPPAS

-----------------SYVTTKDGVQIFYKDWGPRDAPVIHFHHGWPLSADDWDAQLLFFLAHGYRVVAHDRRGHGRSSQVWGHDMDHYADDVAAVVAHLGIQGAVHVGHSTGGGEVVRYMARHPEDKVAKAVLIAAVPPLMVQTPGNPGGLPKSVFDGFQAQVASNRAQFYRDVPAGPFYG-------------YNRPGVEASEGIIGNWWRQGMIGSAKAHYDGIVAFSQT--DFTEDLKGIQQPVLVMHGDDDQIVPYENGVLSAKLLPNGALKTYKGYPHGMPTTHADVINADLLAFIRS---

1zoiA

0.18

0.16

0.88

2.77

wMUSTER

------------------YVTTKDGVQIFYKDWGPRDAPVIHFHHGWPLSADDWDAQLLFFLAHGYRVVAHDRRGHGRSSQVWDHDMDHYADDVAAVVAHLGIQGAVHVGHSTGGGEVVRYMARHPEDKVAKAVLIAAVPPLMVQTPGNPGGLPKSVFDGFQAQVASNRAQFYRDVPAGPFYG-------------YNRPGVEASEGIIGNWWRQGMIGSAKAHYDGIVAFSQT--DFTEDLKGIQQPVLVMHGDDDQIVPYENGVLSAKLLPNGALKTYKGYPHGMPTTHADVINADLLAFIRS---

1zoiA

0.18

0.16

0.88

2.96

wPPAS

-----------------SYVTTKDGVQIFYKDWGPRDAPVIHFHHGWPLSADDWDAQLLFFLAHGYRVVAHDRRGHGRSSQVWGHDMDHYADDVAAVVAHLGIQGAVHVGHSTGGGEVVRYMARHPEDKVAKAVLIAAVPPLMVQTPGNPGGLPKSVFDGFQAQVASNRAQFYRDVPAGP--------------FYGYNRP--GVEASEGIIGNWWRQGMIGSAKAHYDGIVAFSQDFTEDLKGIQQPVLVMHGDDDQIVPYENGVLSAKLLPNGALKTYKGYPHGMPTTHADVINADLLAFIRS---

1zoiA

0.18

0.16

0.89

2.73

dPPAS2

-----------------SYVTTKDGVQIFYKDWGPRDAPVIHFHHGWPLSADDWDAQLLFFLAHGYRVVAHDRRGHGRSSVWDGHDMDHYADDVAAVVAHLGIQGAVHVGHSTGGGEVVRYMARHPEDKVAKAVLIAAVPPLMVQTPGNPGGLPKSVFDGFQAQVASNRAQFYRDVPAGPF-------------YGYNRPGVEASEGIIGNWWRQGMIGSAKAHYDGIVAFSQT--DFTEDLKGIQQPVLVMHGDDDQIVPYENGVLSAKLLPNGALKTYKGYPHGMPTTHADVINADLLAFIRS---

1zoiA

0.18

0.16

0.89

2.86

PPAS

-----------------SYVTTKDGVQIFYKDWGPRDAPVIHFHHGWPLSADDWDAQLLFFLAHGYRVVAHDRRGHGRSSVWDGHDMDHYADDVAAVVAHLGIQGAVHVGHSTGGGEVVRYMARHPEDKVAKAVLIAAVPPLMVQTPGNPGGLPKSVFDGFQAQVASNRAQFYRDVPAGPFYG-------------YNRPGVEASEGIIGNWWRQGMIGSAKAHYDGIVAFSQT--DFTEDLKGIQQPVLVMHGDDDQIVPYENGVLSAKLLPNGALKTYKGYPHGMPTTHADVINADLLAFIRS---

4rncA

0.17

0.15

0.89

2.91

Env-PPAS

--------------MSIREAVSVDGTSIVYRVTGNSAGTPLVLLHGWAQSSQCWGEQVLADLAADYRLIAVDLRGHGYSDAPESDDSANWAGDVAAVLAAEGVENAILLGWSYGGLVICDYLAAHGTGAVAGAVLVGAITSIGRGEKGGKVG--SAMRSAVPGAMSEDPREAIRALGAFGNA-------------------LTGPPEGKGAASQALFGYSLSTRPRVRAALFNRAVGHDELLRNLDIPVLVLHGTDDSVVDVSAGKHAEELIPKSQASYWVGCNHGPFVEDPTRFVSEVRTFISSLAG

1a88A

0.19

0.17

0.89

2.19

MUSTER

-----------------GTVTTSDGTNIFYKDWGPRDGLPVVFHHGWPLSADDWDNQMLFFLSHGYRVIAHDRRGHGRSDQPSTHDMDTYAADVAALTEALDLRGAVHIGHSTGGGEVARYVARAEPGRVAKAVLVSAVPPVMVKSDTNPDGLPLEVFDEFRAALAANRAQFYIDVPSGPF-------------YGFNREGATVSQGLIDHWWLQGMMGAANAHYECIAAFSET--DFTDDLKRIDVPVLVAHGTDDQVVPYAAAPKSAELLANATLKSYEGLPHGMLSTHPEVLNPDLLAFVKS---

1a88A

0.19

0.17

0.89

2.15

dPPAS

-----------------GTVTTSDGTNIFYKDWGPRDGLPVVFHHGWPLSADDWDNQMLFFLSHGYRVIAHDRRGHGRSDPSTGHDMDTYAADVAALTEALDLRGAVHIGHSTGGGEVARYVARAEPGRVAKAVLVSAVPPVMVKSDTNPDGLPLEVFDEFRAALAANRAQFYIDVPSGPF-------------YGFNREGATVSQGLIDHWWLQGMMGAANAHYECIAAFSET--DFTDDLKRIDVPVLVAHGTDDQVVPYDAAPKSAELLANATLKSYEGLPHGMLSTHPEVLNPDLLAFVKS---

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-0.66

Estimated TM-score = 0.63±0.14

Estimated RMSD = 7.7±4.3Å

Download Model 2

C-score=-1.58

Download Model 3

C-score=-1.37

Download Model 4

C-score=-1.08

Download Model 5

C-score=-1.88

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	1zoiA	0.846	1.47	0.176	0.886
2	1a88A	0.843	1.54	0.194	0.886
3	1a8sA	0.831	1.65	0.199	0.880
4	1a8qA	0.828	1.68	0.196	0.877
5	3hi4A	0.824	1.67	0.216	0.873
6	3vdxA	0.815	2.23	0.172	0.886
7	1brtA	0.810	2.17	0.174	0.877
8	1hkhA	0.808	2.18	0.174	0.877
9	3fobB	0.807	2.02	0.218	0.870
10	1zd4A2	0.777	3.60	0.154	0.935

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.29	66	1a8uA	BEZ	Rep, Mult	46,47,111,112,113,139,231,259,285
2	0.12	32	3f9cA	DFP	Rep, Mult	46,47,111,112,113,285,286
3	0.07	22	2wj6C	ZZ8	Rep, Mult	47,49,111,112,113,194,224,227,231,285
4	0.04	11	4etwA	ZMK	Rep, Mult	46,47,112,113,157,158,161,176,189,194,196,228,231,259,285
5	0.03	10	2cjpB	VPR	Rep, Mult	47,112,157,176,186,258,285,286
6	0.02	6	4o08A	PO6	Rep, Mult	47,48,176,177,284,285
7	0.01	2	2psjB	CEI	Rep, Mult	144,150,153,162,168,169,177,260,261,285
8	0.01	3	1cijA	BR	Rep, Mult	47,113,169,172,219,220,223
9	0.01	2	1ukbA	BEZ	Rep, Mult	55,191,194,203,286
10	0.01	2	1xqyA	III	Rep, Mult	184,187,188,191,203,211,220
11	0.01	2	2xuaH	SHF	Rep, Mult	46,47,160,176,179,180,216,224,259
12	0.01	2	2o2hA	DCE	Rep, Mult	147,148,258,259,285
13	0.01	4	1y37A	MG	Rep, Mult	85,86,87,90,227,230,235
14	0.01	2	3v1nA	HPK	Rep, Mult	45,46,51,52,55,56,195,203,208,212,286,289
15	0.01	2	1b6gA	GOL	Rep, Mult	25,80
16	0.00	1	1xrmA	III	Rep, Mult	209,212
17	0.00	1	1b6gA	GOL	Rep, Mult	6,7,10
18	0.00	1	1cijA	BR	Rep, Mult	182,184,204,213
19	0.00	1	1xrrA	PRO	Rep, Mult	187,191,220,226,227
20	0.00	1	2ocgA	MN	Rep, Mult	29,51,72,78

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.405	1zoiA	0.846	1.47	0.176	0.886	3.1.1.-	112,257,285
2	0.399	1a8qA	0.828	1.68	0.196	0.877	1.11.1.10	112,257,285
3	0.348	1a8sA	0.831	1.65	0.199	0.880	1.11.1.10	112,257
4	0.316	1mt3A	0.735	3.60	0.138	0.864	3.4.11.5	257,285
5	0.312	1dwoA	0.635	3.44	0.104	0.756	4.1.2.37	112,257,285
6	0.309	3e3aB	0.770	2.51	0.157	0.867	1.11.1.-	29,46,51,72
7	0.294	1a88B	0.843	1.54	0.194	0.886	1.11.1.10	NA
8	0.281	2ocgA	0.705	2.31	0.171	0.779	3.1.-.-	112,257,260,277,285
9	0.265	1va4A	0.825	1.66	0.212	0.873	3.1.1.2	112
10	0.247	1mj5A	0.737	3.04	0.142	0.867	3.8.1.5	285
11	0.206	2r11D	0.708	3.33	0.138	0.838	3.1.1.1	75
12	0.203	2og1A	0.774	2.70	0.183	0.880	3.7.1.8	NA
13	0.176	1u2eA	0.776	2.98	0.159	0.893	3.7.1.-	112,257,285
14	0.143	1ehyA	0.746	3.16	0.164	0.873	3.3.2.10	229,257,285
15	0.132	3hjuA	0.705	3.41	0.150	0.828	3.1.1.23	77,112
16	0.112	3bf7A	0.656	3.31	0.131	0.769	3.1.-.-	112
17	0.097	1qj4A	0.635	3.45	0.102	0.756	4.1.2.37	112,257,285
18	0.067	1i6wB	0.464	2.66	0.127	0.523	3.1.1.3	257
19	0.060	1a7uA	0.811	2.17	0.174	0.877	1.11.1.10	112,257,285
20	0.060	2psfA	0.756	3.14	0.124	0.893	1.13.12.5	285
21	0.060	2zjfA	0.772	3.67	0.155	0.929	3.3.2.3	293,300
22	0.060	1j1iA	0.721	2.47	0.181	0.808	3.7.1.8	54,112,260
23	0.060	2vavB	0.741	3.36	0.121	0.886	2.3.1.175	112,190
24	0.060	2pu5A	0.774	2.70	0.183	0.880	3.7.1.8	30
25	0.060	1c4xA	0.752	2.70	0.162	0.857	3.7.1.8	112
26	0.060	1iunB	0.749	2.79	0.167	0.857	3.7.1.9	257
27	0.060	1y37A	0.756	3.08	0.153	0.893	3.8.1.3	76
28	0.060	1azwA	0.722	3.49	0.160	0.873	3.4.11.5	NA
29	0.060	2vf2A	0.763	3.05	0.172	0.886	3.7.1.8	48,75,77
30	0.060	1m33A	0.724	2.52	0.151	0.815	3.1.1.1	NA
31	0.060	2qvbB	0.734	3.27	0.130	0.877	3.8.1.5	285
32	0.060	2v9zA	0.733	3.47	0.171	0.893	3.8.1.5	NA
33	0.060	2e3jA	0.774	3.63	0.155	0.929	3.3.2.3	NA
34	0.060	2pl5A	0.738	3.52	0.108	0.877	2.3.1.31	112,257,285
35	0.060	1qtrA	0.724	3.32	0.165	0.864	3.4.11.5	257,285
36	0.060	1a88A	0.843	1.54	0.194	0.886	1.11.1.10	112,257
37	0.060	3a2lA	0.731	3.20	0.126	0.873	3.8.1.5	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.41	0.820	2.17	0.17	0.89	4qesA	GO:0003723 GO:0003824 GO:0004601 GO:0005198 GO:0005576 GO:0005654 GO:0005829 GO:0005886 GO:0016020 GO:0016032 GO:0016491 GO:0017000 GO:0019012 GO:0019061 GO:0019062 GO:0019064 GO:0019065 GO:0019068 GO:0019070 GO:0019072 GO:0019076 GO:0019083 GO:0030666 GO:0030683 GO:0031904 GO:0039573 GO:0039660 GO:0042025 GO:0046761 GO:0055036 GO:0055114 GO:0075733 GO:0098869
1	0.38	0.828	1.68	0.20	0.88	1a8qA	GO:0003824 GO:0004601 GO:0016491 GO:0017000 GO:0055114 GO:0098869
2	0.34	0.705	3.41	0.15	0.83	3hjuA	GO:0004622 GO:0005654 GO:0005737 GO:0005789 GO:0005829 GO:0005886 GO:0006629 GO:0006631 GO:0006633 GO:0006954 GO:0009966 GO:0016020 GO:0016042 GO:0016787 GO:0019369 GO:0019433 GO:0019898 GO:0036155 GO:0042803 GO:0046464 GO:0047372 GO:0050727 GO:0051930 GO:0052689 GO:2000124
3	0.34	0.755	2.17	0.14	0.83	4ih4A	GO:0005634 GO:0005737 GO:0010223 GO:0016787 GO:1901601 GO:1902348
4	0.33	0.752	2.70	0.16	0.86	1c4xA	GO:0016787 GO:0018774
5	0.33	0.749	2.79	0.17	0.86	1iunB	GO:0003824 GO:0016787
6	0.33	0.656	3.31	0.13	0.77	3bf7A	GO:0005829 GO:0016787 GO:0016790 GO:0052689
7	0.32	0.768	2.90	0.17	0.87	4rncA	GO:0016787 GO:0052689
8	0.32	0.844	1.67	0.17	0.89	4dgqA	GO:0004601 GO:0016491 GO:0016691 GO:0055114 GO:0098869
9	0.31	0.742	2.58	0.13	0.83	3v48A	GO:0006212 GO:0016787 GO:0016811 GO:0019740
10	0.31	0.750	3.11	0.14	0.89	5esrA	GO:0003824 GO:0016787 GO:0018786
11	0.31	0.641	3.77	0.14	0.78	1y7iB	GO:0002376 GO:0006952 GO:0008152 GO:0009862 GO:0016298 GO:0016787 GO:0045087 GO:0080031
12	0.31	0.725	3.10	0.16	0.85	4g8bA	GO:0003824 GO:0016787 GO:0016788
13	0.31	0.741	3.28	0.17	0.89	4kajA	GO:0003824 GO:0009636 GO:0016787 GO:0018786
14	0.31	0.761	2.67	0.19	0.86	4x00A	GO:0016787
15	0.30	0.682	3.45	0.16	0.81	3qitB	GO:0003824 GO:0008152 GO:0016740 GO:0031177
16	0.30	0.746	3.23	0.13	0.89	5bovB	GO:0003824 GO:0016787
17	0.30	0.748	2.74	0.15	0.84	4ns4A	GO:0016787 GO:0016788
18	0.30	0.733	2.56	0.14	0.83	1m33A	GO:0005737 GO:0009102 GO:0016787 GO:0052689 GO:0090499
19	0.29	0.755	3.09	0.14	0.88	4b9aA	GO:0003824 GO:0009062 GO:0016298 GO:0016787
20	0.29	0.812	2.16	0.21	0.88	3fobA	GO:0003824 GO:0004601 GO:0009636 GO:0016491 GO:0016691 GO:0016787 GO:0019806 GO:0055114 GO:0098869
21	0.29	0.843	1.54	0.19	0.89	1a88A	GO:0003824 GO:0004601 GO:0016491 GO:0016691 GO:0055114 GO:0098869
22	0.29	0.760	3.07	0.15	0.90	3b12A	GO:0003824 GO:0016787 GO:0018785
23	0.28	0.707	3.50	0.15	0.84	2yysA	GO:0006508 GO:0008233
24	0.28	0.759	2.28	0.16	0.83	4dnqI	GO:0010223 GO:0016787 GO:0016788 GO:1901601
25	0.28	0.763	2.18	0.15	0.84	2xuaH	GO:0016787 GO:0042952 GO:0047570
26	0.28	0.825	1.66	0.21	0.87	3heaA	GO:0003824 GO:0004064 GO:0004601 GO:0016491 GO:0016787 GO:0055114 GO:0098869
27	0.28	0.737	3.23	0.15	0.87	4pw0A	GO:0016787
28	0.27	0.808	2.18	0.17	0.88	1hkhA	GO:0003824 GO:0004601 GO:0098869
29	0.26	0.751	3.08	0.17	0.89	3u1tB	GO:0003824
30	0.26	0.770	2.51	0.16	0.87	3e3aB	GO:0003824 GO:0004601 GO:0009062 GO:0016298 GO:0016491 GO:0055114 GO:0098869
31	0.26	0.846	1.47	0.18	0.89	1zoiA
32	0.26	0.763	3.05	0.17	0.89	2vf2A	GO:0005618 GO:0005886 GO:0006629 GO:0006694 GO:0016042 GO:0016787 GO:0018774 GO:0019439 GO:0034820 GO:0044117 GO:0102296
33	0.25	0.735	3.60	0.14	0.86	1mt3A	GO:0004177 GO:0006508 GO:0008233 GO:0016787
34	0.25	0.774	3.44	0.15	0.93	4haiA	GO:0000287 GO:0003824 GO:0004301 GO:0005102 GO:0005737 GO:0005777 GO:0005829 GO:0006629 GO:0006805 GO:0006874 GO:0006954 GO:0008152 GO:0008217 GO:0009636 GO:0010628 GO:0015643 GO:0016311 GO:0016787 GO:0016791 GO:0017144 GO:0019373 GO:0019439 GO:0033885 GO:0042577 GO:0042632 GO:0042803 GO:0045909 GO:0046272 GO:0046839 GO:0046872 GO:0070062 GO:0072593 GO:0090181
35	0.25	0.754	3.28	0.13	0.89	4psuA	GO:0016787
36	0.24	0.726	2.66	0.15	0.82	4nmwA	GO:0005737 GO:0009102 GO:0016787 GO:0052689
37	0.24	0.773	2.87	0.17	0.88	4f0jA	GO:0003824 GO:0016787
38	0.24	0.722	2.77	0.18	0.83	3kxpA	GO:0016787 GO:0042803 GO:0042820 GO:0047411
39	0.24	0.690	3.50	0.16	0.82	3p2mA	GO:0052689
40	0.24	0.751	3.02	0.15	0.87	4ccyB	GO:0005737 GO:0016787 GO:0052689
41	0.23	0.534	2.89	0.17	0.61	4fhzA	GO:0016787
42	0.22	0.761	2.54	0.17	0.85	1womA	GO:0016787
43	0.22	0.732	3.35	0.12	0.87	2r11D	GO:0016787 GO:0052689
44	0.22	0.643	3.12	0.14	0.75	2wtmA
45	0.22	0.734	3.26	0.12	0.88	3afiB	GO:0003824 GO:0016787 GO:0018786 GO:0042206 GO:0042802
46	0.21	0.768	3.53	0.16	0.92	4ufoA	GO:0003824 GO:0016787
47	0.21	0.738	3.40	0.18	0.90	3sk0A	GO:0003824 GO:0009636 GO:0016787 GO:0018786
48	0.21	0.761	3.66	0.14	0.92	5aljA	GO:0000287 GO:0003824 GO:0004301 GO:0005102 GO:0005737 GO:0005777 GO:0005829 GO:0006629 GO:0006805 GO:0006874 GO:0006954 GO:0008152 GO:0008217 GO:0009636 GO:0010628 GO:0015643 GO:0016311 GO:0016787 GO:0016791 GO:0017144 GO:0019373 GO:0019439 GO:0033885 GO:0042577 GO:0042632 GO:0042803 GO:0045909 GO:0046272 GO:0046839 GO:0046872 GO:0070062 GO:0072593 GO:0090181
49	0.21	0.831	1.65	0.20	0.88	1a8sA	GO:0003824 GO:0004601 GO:0016491 GO:0016691 GO:0055114 GO:0098869
50	0.20	0.609	3.29	0.12	0.72	5hk8A	GO:0005737 GO:0005829 GO:0010150 GO:0015996 GO:0016787 GO:0016788 GO:0033310 GO:0035560 GO:0042803 GO:0052689 GO:0070988 GO:0080030 GO:0080032
51	0.20	0.772	3.28	0.13	0.91	4opmA	GO:0004806 GO:0016787
52	0.19	0.731	3.11	0.16	0.87	4k2aC	GO:0003824 GO:0016787 GO:0018786
53	0.19	0.721	2.47	0.18	0.81	1j1iA	GO:0016787
54	0.16	0.776	2.98	0.16	0.89	1u2eA	GO:0003824 GO:0005737 GO:0016787 GO:0018771 GO:0019380 GO:0019439 GO:0019622 GO:0042803 GO:0052823
55	0.16	0.735	3.19	0.14	0.87	2wm2C	GO:0016491 GO:0016702 GO:0019439 GO:0050586 GO:0051213 GO:0055114
56	0.16	0.755	2.90	0.13	0.87	3qyjA	GO:0003824
57	0.16	0.774	2.70	0.18	0.88	2og1A	GO:0003824 GO:0016787 GO:0016823 GO:0018771 GO:0018774 GO:0019439
58	0.16	0.774	3.63	0.15	0.93	2e3jA	GO:0003824 GO:0016787
59	0.15	0.749	2.88	0.15	0.86	4i3fA	GO:0016787
60	0.15	0.766	2.41	0.18	0.85	3om8B	GO:0016787 GO:0042952 GO:0047570
61	0.15	0.762	3.26	0.12	0.90	3vvlB	GO:0004414 GO:0005737 GO:0008652 GO:0009001 GO:0009086 GO:0016740 GO:0016746 GO:0017000
62	0.14	0.747	3.04	0.10	0.87	4io0A	GO:0003824 GO:0008152 GO:0016787 GO:0016798 GO:0047405
63	0.14	0.740	3.09	0.18	0.88	2xt0A	GO:0003824
64	0.14	0.735	3.48	0.13	0.87	3wmrA	GO:0006508 GO:0008233 GO:0016787
65	0.13	0.750	3.33	0.15	0.90	1be0A	GO:0003824 GO:0009636 GO:0016787 GO:0018786 GO:0019260
66	0.13	0.722	3.49	0.16	0.87	1azwA	GO:0004177 GO:0005737 GO:0006508 GO:0008233 GO:0016787
67	0.13	0.724	3.32	0.17	0.86	1qtrA	GO:0004177 GO:0005737 GO:0006508 GO:0008233 GO:0016787
68	0.10	0.630	3.61	0.11	0.76	2wfmA	GO:0009820 GO:0016787 GO:0050529 GO:0052689
69	0.09	0.552	2.52	0.15	0.62	3trdA	GO:0016787
70	0.07	0.768	3.61	0.15	0.93	1cqzB	GO:0000287 GO:0003824 GO:0004301 GO:0005102 GO:0005737 GO:0005777 GO:0005829 GO:0006629 GO:0008152 GO:0009636 GO:0010628 GO:0015643 GO:0016311 GO:0016787 GO:0016791 GO:0019439 GO:0033885 GO:0042577 GO:0042632 GO:0042803 GO:0046272 GO:0046839 GO:0046872 GO:0070062 GO:0090181
71	0.07	0.487	3.07	0.12	0.57	3og9A	GO:0016787

Consensus prediction of GO terms

Molecular Function	GO:0004601	GO:0003723	GO:0039660	GO:0042803	GO:0004622	GO:0047372	GO:0018774
GO-Score	0.64	0.41	0.41	0.34	0.34	0.34	0.33
Biological Processes	GO:0098869	GO:0055114	GO:0017000	GO:0019061	GO:0019070	GO:0019083	GO:0046761	GO:0019062	GO:0019064	GO:0019072	GO:0075733	GO:0039573	GO:0019065	GO:0006633	GO:0051930	GO:0019369	GO:0019433	GO:0036155	GO:2000124	GO:1902348	GO:0010223	GO:1901601
GO-Score	0.64	0.64	0.64	0.41	0.41	0.41	0.41	0.41	0.41	0.41	0.41	0.41	0.41	0.34	0.34	0.34	0.34	0.34	0.34	0.34	0.34	0.34
Cellular Component	GO:0005654	GO:0005829	GO:0005886	GO:0005576	GO:0055036	GO:0030666	GO:0031904	GO:0042025	GO:0019898	GO:0005789
GO-Score	0.61	0.61	0.61	0.41	0.41	0.41	0.41	0.41	0.34	0.34

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv3312c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]