Threading Zmax Znorm MUSTER 4.29 0.74 dPPAS 6.65 0.71 wdPPAS 5.25 0.56 wMUSTER 3.94 0.68 wPPAS 4.23 0.60 dPPAS2 11.15 1.06 PPAS 5.30 0.76 Env-PPAS 5.39 0.67 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=11295) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -3.22 0.35+-0.12 14.9+-3.6 3066 0.055 model2 -4.50 718 0.015 model3 -4.88 604 0.010 model4 -5.00 264 0.006 model5 -4.71 260 0.012 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).