Threading Zmax Znorm MUSTER 15.07 2.60 dPPAS 44.35 4.77 wdPPAS 56.57 6.08 wMUSTER 18.67 3.22 wPPAS 36.65 5.24 dPPAS2 155.27 14.79 PPAS 30.48 4.35 Env-PPAS 68.05 8.51 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=4518) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 0.94 0.84+-0.08 4.9+-3.2 4037 0.412 model2 0.39 1710 0.240 model3 -2.11 150 0.020 model4 0.75 1870 0.342 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).