I-TASSER results

Input Sequence in FASTA format

>protein (229 residues)
MLRADPVGPRITYYDDATGERIELSAVTLANWAAKTGNLLRDELAAGPASRVAILLPAHW
QTAAVLFGVWWIGAQAILDDSPADVALCTADRLAEADAVVNSAAVAGEVAVLSLDPFGRP
ATGLPVGVTDYATAVRVHGDQIVPEHNPGPVLAGRSVEQILRDCAASAAARGLTAADRVL
STASWAGPDELVDGLLAILAAGASLVQVANPDPAMLQRRIATEKVTRVL

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 \| \| \| \| \| \| \| \| \| \| \| MLRADPVGPRITYYDDATGERIELSAVTLANWAAKTGNLLRDELAAGPASRVAILLPAHWQTAAVLFGVWWIGAQAILDDSPADVALCTADRLAEADAVVNSAAVAGEVAVLSLDPFGRPATGLPVGVTDYATAVRVHGDQIVPEHNPGPVLAGRSVEQILRDCAASAAARGLTAADRVLSTASWAGPDELVDGLLAILAAGASLVQVANPDPAMLQRRIATEKVTRVL
Prediction	CCCCCCCCCEEEEHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHCCCCHHHHHHHHHHHHHCCEEHCCCCCCCEEEEHCCCCCCCHHHHHCCCCCCCEEEHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEHCCCCCCHHHHHHHHHHHHHCCEEEHCCCCCHHHHHHHHHHHCCCEHC
Conf.Score	9888999978999768999678774999999999999999998799999689998899888999999999988788679999876787454444554555545666766786577557888888987788765556778766789999876445679999999999999989998878998679887578999999998768789987999999999999998998659
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 \| \| \| \| \| \| \| \| \| \| \| MLRADPVGPRITYYDDATGERIELSAVTLANWAAKTGNLLRDELAAGPASRVAILLPAHWQTAAVLFGVWWIGAQAILDDSPADVALCTADRLAEADAVVNSAAVAGEVAVLSLDPFGRPATGLPVGVTDYATAVRVHGDQIVPEHNPGPVLAGRSVEQILRDCAASAAARGLTAADRVLSTASWAGPDELVDGLLAILAAGASLVQVANPDPAMLQRRIATEKVTRVL
Prediction	6345437210000025454232301232023002300410254241434110001013102000000000200010014555131210124323414322443433321100002213343451231021102203433130032344312202220320032023104437045310000013233331021001200100000000341316302510552502344
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCCEEEEHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHCCCCHHHHHHHHHHHHHCCEEHCCCCCCCEEEEHCCCCCCCHHHHHCCCCCCCEEEHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEHCCCCCCHHHHHHHHHHHHHCCEEEHCCCCCHHHHHHHHHHHCCCEHC
MLRADPVGPRITYYDDATGERIELSAVTLANWAAKTGNLLRDELAAGPASRVAILLPAHWQTAAVLFGVWWIGAQAILDDSPADVALCTADRLAEADAVVNSAAVAGEVAVLSLDPFGRPATGLPVGVTDYATAVRVHGDQIVPEHNPGPVLAGRSVEQILRDCAASAAARGLTAADRVLSTASWAGPDELVDGLLAILAAGASLVQVANPDPAMLQRRIATEKVTRVL

5keiA1

0.20

0.19

0.97

1.81

MUSTER

AARTWPDHIAVIDAD------HRHTYAELDRLADRAAAGIAGL-GIRPGDRVLVQLPNTAEFAVALFGLLRAGAVPVMCLPGHRALVVADTHRDLARELVRSHPDVRHVLVDGDAAEFLSWAEVTRAAPGPVPEIAPDPALVSGGTTGAPKLIPRTHQDYVYNATASAELCRLTADDVYLVALPAAHFPLACPGLLGAMTVGATTVFTTDPSPEAAFAAIDEHGVTATA

3dlpX1

0.17

0.15

0.89

2.44

dPPAS

AATRAPDHCALAVPARG----LRLTHAELRARVEAVAARLHADG-LRPQQRVAVVAPNSADVVIAILALHRLGAVPALLNPRLKSAAVIAVGRQVADAIFQSGSGARIIFLGDLVRDGEPYSYGPPIEDPQREPAQPAFIFYTSGTTGLPKAAIIPQRAAESRVLFMSTQVGLGRHNVVLGLMPLYHVVGFFAVLVAALALDGTYVVVE--------------------

3vnqA1

0.16

0.15

0.94

3.73

wdPPAS

VAATAPERTALSAED------DRISYGRLDAWSDAVARTLLAE--VRPGDRVALRMSPGAEAIVAILAILKCGAAYVPVDLRNPVSRSDFILADSGASALIGEPHEGCAVTRVVRTAA--VAECKDAEAPGPGAEDMAYVIYTSGTTGNPKGVPVRHANVLALLAGAPSVFDFSGDDRWLLFHSLS-FDFSVWEIWGAFSTGAELVVLPARTPEQYLAVIIDRGVTV--

3vnqA1

0.16

0.15

0.94

3.20

wMUSTER

VAATAPERTALSAED------DRISYGRLDAWSDAVARTLLAE--VRPGDRVALRMSPGAEAIVAILAILKCGAAYVPVDLRNPVSRSDFILADSGASALIGEPHEGCAVTRVVRTAA--VAECKDAEAPGPGAEDMAYVIYTSGTTGNPKGVPVRHANVLALLAGAPSVFDFSGDDRWLLFHSLS-FDFSVWEIWGAFSTGAELVVLPARTPEQYLAVIIDRGVTV--

3vnqA1

0.16

0.15

0.94

3.96

wPPAS

LAATAPERTALSAED------DRISYGRLDAWSDAVARTLLAE--VRPGDRVALRMSPGAEAIVAILAILKCGAAYVPVDLRNPVSRSDFILADSGASALIGEPHEGCAVTRVVRTA--AVAECKDAEAPGPGAEDMAYVIYTSGTTGNPKGVPVRHANVLALLAGAPSVFDFSGDDRWLLFHSLS-FDFSVWEIWGAFSTGAELVVLPARTPEQYLAVIIDRGVTV--

3dlpX1

0.17

0.15

0.89

4.14

dPPAS2

AATRAPDHCALAVPARG----LRLTHAELRARVEAVAARLHADG-LRPQQRVAVVAPNSADVVIAILALHRLGAVPALLNPRLKSAAVIAVGRQVADAIFQSGSGARIIFLGDLVRDGEPYSYGPPIEDPQREPAQPAFIFYTSGTTGLPKAAIIPQRAAESRVLFMSTQVGLGRHNVVLGLMPLYHVVGFFAVLVAALALDGTYVVVE--------------------

3iplA1

0.13

0.12

0.91

3.01

PPAS

QAQQNGHHIAITD-----GQE-SYTYQNLYCEASLLAKRLKAY----QQSRVGLYIDNSIQSIILIHACWLANIEIAMINTRLTPNEMTNQMRSIDVQLILPLELRGFQIVSLDDESPSNILNTSFNLDDIAS-------MFTSGTTGPQKAVPQTFRNHYASAIGCKESLGFDRDTNWLSVLPIYH-ISGLSVLLRAVIEGFTVRIVDKFNAEQILTMIKNERITH--

5c5hA1

0.12

0.11

0.89

3.95

Env-PPAS

WRQVRGETIALRLND------EQLNWRELCARVDELASGFAVQG-VVEGSGVMLRAWNTPQTLLAWLALLQCGARVLPVNPQLPQPLLEELLPNLTLQF---------ALVPDGENTFPALTSLHIQLVEGAHAATWQPTTLTS-STGLPKAAVHTYQAHLASAQGVLSLIPFGDHDDWLLSLPLFH-VSGQGIMWKWLYAGARMTVRDKQPLEQMLA-----GCTH--

3vnqA

0.16

0.15

0.95

1.76

MUSTER

VAATAPERTALSAED------DRISYGRLDAWSDAVARTLLAE--VRPGDRVALRMSPGAEAIVAILAILKCGAAYVPVDLRNPVSRSDFILADSGASALIGEPHEGCAVTRVVRTAA--VAECKDAEAPGPGAEDMAYVIYTSGTTGNPKGVPVRHANVLALLAGAPSVFDFSGDDRWLLFHSLS-FDFSVWEIWGAFSTGAELVVLPARTPEQYLAVIIDRGVTVIN

3iplA1

0.12

0.10

0.90

2.40

dPPAS

QAQQNGHHIAITDGQE------SYTYQNLYCEASLLAKRLKAY----QQSRVGLYIDNSIQSIILIHACWLANIEIAMINTRLTPN----------EMTNQMRSIDVQLIFCTLPLELRGFQSLDDESPSNILNTSFNLDDFTSGTTGPQKAVPQTFRNHYASAIGCKESLGFDRDTNWLSVLPIYH-ISGLSVLLRAVIEGFTVRIVDKFNAEQILTMIKNERITH--

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=0.71

Estimated TM-score = 0.81±0.09

Estimated RMSD = 4.2±2.8Å

Download Model 2

C-score=-1.31

Download Model 3

C-score=-2.27

Download Model 4

C-score=-2.63

Download Model 5

C-score=-3.07

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	3vnqA	0.910	1.60	0.151	0.956
2	1ry2A1	0.907	1.96	0.127	0.996
3	3t5bA	0.900	1.70	0.126	0.974
4	3b7wA1	0.897	2.00	0.128	0.991
5	1pg3B	0.896	2.09	0.171	0.996
6	5apbA	0.894	1.81	0.173	0.961
7	2vsqA	0.894	1.72	0.168	0.961
8	4d4gA	0.892	1.74	0.118	0.965
9	5es5A	0.891	1.76	0.158	0.965
10	4wd1A	0.887	2.05	0.164	0.983

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.20	13	1pg3B	COA	Rep, Mult	80,81,82,183,187,189,210
2	0.08	5	4l6v6	CLA	Rep, Mult	25,29
3	0.03	2	3rg2H	SVS	Rep, Mult	188,189,193
4	0.03	2	1t5dX	174	Rep, Mult	142,144,145,149,150
5	0.03	2	3rixA	923	Rep, Mult	32,59,61,69,115,116,117
6	0.03	2	3r44A	HIS	Rep, Mult	158,161
7	0.01	1	4kp4A	MG	Rep, Mult	38,41
8	0.01	1	2wd9A	IBP	Rep, Mult	77,78,152,153,154
9	0.01	1	4dg8A	BU3	Rep, Mult	183,184,229
10	0.01	1	1swiC	BNZ	Rep, Mult	29,33
11	0.01	1	4ogqE	1O2	Rep, Mult	29,33,36,37,44
12	0.01	1	3cw9A	AMP	Rep, Mult	143
13	0.01	1	5c5hB	MG	Rep, Mult	57,58,184
14	0.01	1	2qvzX	3BZ	Rep, Mult	166,191,192,193
15	0.01	1	1zs4B	NUC	Rep, Mult	32,35
16	0.01	1	2wd9C	IBP	Rep, Mult	60,62,63,207,209

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.107	3ivrA	0.871	1.93	0.205	0.956	6.2.1.3	17,24
2	0.060	1ba3A	0.865	2.10	0.086	0.969	1.13.12.7	NA
3	0.060	1kolB	0.476	4.26	0.072	0.681	1.2.1.46	80
4	0.060	1amuA	0.873	1.71	0.130	0.943	5.1.1.11	NA
5	0.060	2dphA	0.479	4.04	0.078	0.677	1.2.99.4	NA
6	0.060	3l8cB	0.870	2.03	0.113	0.965	6.1.1.13	61
7	0.060	2d1rA	0.861	2.19	0.107	0.978	1.13.12.7	NA
8	0.060	2vk1A	0.470	4.96	0.050	0.712	4.1.1.1	NA
9	0.060	2vjyA	0.473	5.10	0.060	0.729	4.1.1.1	NA
10	0.060	3iplA	0.843	1.87	0.098	0.917	6.2.1.26	182
11	0.060	1ry2A	0.907	1.96	0.127	0.996	6.2.1.1	76
12	0.060	2djiA	0.468	5.18	0.044	0.760	1.2.3.3	76
13	0.060	2ji6A	0.474	5.26	0.063	0.773	4.1.1.8	NA
14	0.060	3etcB	0.881	2.19	0.106	0.987	6.2.1.-	NA
15	0.060	1jqkF	0.464	5.79	0.046	0.799	1.2.99.2	196,198
16	0.060	3fccA	0.858	2.00	0.096	0.952	6.1.1.13	NA
17	0.060	2dfvA	0.467	4.35	0.082	0.672	1.1.1.103	NA
18	0.060	1ozgA	0.467	5.21	0.083	0.760	2.2.1.6	NA
19	0.060	2v7bA	0.864	1.82	0.111	0.943	6.2.1.25	NA
20	0.060	2ihvA	0.465	5.46	0.067	0.747	2.5.1.66	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.22	0.894	2.09	0.09	0.99	3g7sA	GO:0003824 GO:0008152 GO:0016874
1	0.22	0.907	1.96	0.13	1.00	1ry2A	GO:0000166 GO:0003824 GO:0003987 GO:0005524 GO:0005634 GO:0005737 GO:0005739 GO:0005783 GO:0005829 GO:0006085 GO:0008152 GO:0016208 GO:0016573 GO:0016874 GO:0016880 GO:0019427 GO:0019654 GO:0043231
2	0.22	0.894	2.10	0.17	1.00	2p20A	GO:0000166 GO:0003824 GO:0003987 GO:0005524 GO:0006935 GO:0008152 GO:0016208 GO:0016874 GO:0019427 GO:0046872
3	0.21	0.885	1.78	0.12	0.97	4eatB	GO:0003824 GO:0005524 GO:0008152 GO:0016405 GO:0016874
4	0.21	0.892	1.76	0.12	0.97	4d56A	GO:0003824 GO:0008152
5	0.21	0.881	2.07	0.14	0.98	3dlpX	GO:0000166 GO:0003824 GO:0008152 GO:0016020 GO:0016021 GO:0016874 GO:0046872
6	0.21	0.894	1.72	0.17	0.96	2vsqA	GO:0003824 GO:0008152 GO:0009058 GO:0016788 GO:0016874 GO:0017000 GO:0030435 GO:0031177
7	0.21	0.891	1.93	0.15	0.98	5bsmA	GO:0000166 GO:0003824 GO:0005524 GO:0008152 GO:0009698 GO:0016207 GO:0016874
8	0.21	0.897	2.00	0.13	0.99	3b7wA	GO:0000166 GO:0003824 GO:0005524 GO:0005739 GO:0005759 GO:0006629 GO:0006631 GO:0008152 GO:0016874 GO:0036112 GO:0042593 GO:0046872 GO:0047760 GO:0070328
9	0.21	0.860	1.82	0.16	0.93	3wv5B	GO:0003824 GO:0008152
10	0.21	0.880	2.09	0.18	0.98	5ifiA	GO:0000166 GO:0003824 GO:0003987 GO:0005524 GO:0008152 GO:0016208 GO:0016874 GO:0019427
11	0.21	0.871	1.93	0.20	0.96	3ivrA	GO:0001676 GO:0003824 GO:0004467 GO:0008152 GO:0016874 GO:0102391
12	0.21	0.880	2.13	0.13	0.98	3tsyA	GO:0000166 GO:0003824 GO:0005524 GO:0005737 GO:0008152 GO:0009058 GO:0009698 GO:0016207 GO:0016740 GO:0016746 GO:0016747 GO:0016874
13	0.21	0.858	2.00	0.10	0.95	3fccA	GO:0000166 GO:0003824 GO:0005524 GO:0005737 GO:0008152 GO:0016874 GO:0016876 GO:0047473 GO:0070395
14	0.21	0.885	1.91	0.16	0.97	5es8B	GO:0003824 GO:0008152 GO:0009058 GO:0016742 GO:0016874 GO:0017000 GO:0031177
15	0.21	0.866	2.13	0.16	0.97	3rg2C	GO:0000166 GO:0003824 GO:0005524 GO:0005829 GO:0008152 GO:0008668 GO:0008908 GO:0009239 GO:0016020 GO:0016740 GO:0016746 GO:0016787 GO:0016874 GO:0019290 GO:0047527
16	0.21	0.880	2.21	0.11	0.99	4r0mA	GO:0003824 GO:0008152 GO:0016740 GO:0031177
17	0.21	0.852	2.10	0.12	0.95	4dg9A	GO:0000166 GO:0003824 GO:0008152
18	0.21	0.876	1.93	0.18	0.96	4zxjA	GO:0000166 GO:0003824 GO:0005524 GO:0005829 GO:0005886 GO:0008152 GO:0009058 GO:0009239 GO:0009366 GO:0016740 GO:0016779 GO:0016788 GO:0016874 GO:0031177 GO:0043041 GO:0047527
19	0.20	0.880	2.16	0.18	0.99	1ultA	GO:0000166 GO:0001676 GO:0003824 GO:0004467 GO:0005524 GO:0006629 GO:0006631 GO:0008152 GO:0016874 GO:0046872 GO:0102391
20	0.20	0.867	2.07	0.17	0.97	1md9A	GO:0000166 GO:0003824 GO:0005524 GO:0005737 GO:0008152 GO:0008668 GO:0016874 GO:0019290
21	0.10	0.867	1.82	0.16	0.94	3wv4A	GO:0003824 GO:0008152
22	0.09	0.834	2.30	0.13	0.94	4lgcA	GO:0003824 GO:0006629 GO:0008152 GO:0008202 GO:0016042 GO:0016874 GO:0030573
23	0.08	0.849	2.06	0.16	0.93	4gr4C	GO:0003824 GO:0008152 GO:0008168 GO:0016874 GO:0032259 GO:0055114
24	0.08	0.826	2.11	0.17	0.92	3nyqA	GO:0000166 GO:0003824 GO:0008152
25	0.08	0.844	1.97	0.10	0.93	4pzpA	GO:0000166 GO:0003824 GO:0005524 GO:0005737 GO:0008152 GO:0016874 GO:0016876 GO:0047473 GO:0070395
26	0.08	0.871	2.20	0.13	0.97	3iteB	GO:0003824 GO:0008152 GO:0031177
27	0.08	0.858	1.83	0.14	0.93	4gxqA	GO:0000166 GO:0003824 GO:0005524 GO:0008152 GO:0016020 GO:0016021 GO:0016405 GO:0016874 GO:0018858
28	0.08	0.878	1.98	0.13	0.97	5busA	GO:0000166 GO:0003824 GO:0005524 GO:0008152 GO:0008756 GO:0009234 GO:0016874
29	0.07	0.875	1.98	0.13	0.97	4fuqC	GO:0000166 GO:0003824 GO:0005524 GO:0008152 GO:0016874
30	0.07	0.864	1.82	0.11	0.94	2v7bA	GO:0003824 GO:0005524 GO:0008152 GO:0016020 GO:0016021 GO:0016405 GO:0016874 GO:0018858
31	0.07	0.833	2.44	0.15	0.95	3t5aA	GO:0000166 GO:0003824 GO:0004321 GO:0005524 GO:0005886 GO:0006629 GO:0006631 GO:0006633 GO:0008152 GO:0008610 GO:0016874 GO:0044119 GO:0052170 GO:0052572 GO:0070566 GO:0071770
32	0.07	0.870	2.03	0.11	0.97	3l8cB	GO:0000166 GO:0003824 GO:0005524 GO:0005737 GO:0008152 GO:0016874 GO:0016876 GO:0047473 GO:0070395
33	0.07	0.843	1.87	0.10	0.92	3iplA	GO:0000166 GO:0003824 GO:0005524 GO:0008152 GO:0008756 GO:0009234 GO:0016874
34	0.07	0.888	1.69	0.12	0.96	3r44A	GO:0000166 GO:0001101 GO:0001676 GO:0003824 GO:0004321 GO:0004467 GO:0005524 GO:0005618 GO:0005829 GO:0005886 GO:0006629 GO:0006631 GO:0006633 GO:0008152 GO:0016020 GO:0016874 GO:0044119 GO:0102391
35	0.07	0.892	1.69	0.14	0.97	4wv3B	GO:0003824 GO:0005524 GO:0008152 GO:0016405 GO:0016874
36	0.07	0.873	1.71	0.13	0.94	1amuA	GO:0000166 GO:0003824 GO:0005524 GO:0008152 GO:0016853 GO:0016874 GO:0017000 GO:0047462
37	0.07	0.881	2.19	0.11	0.99	3etcB	GO:0003824 GO:0008152
38	0.07	0.823	2.00	0.12	0.91	5c5hB	GO:0000166 GO:0003824 GO:0005524 GO:0008152 GO:0008756 GO:0009234 GO:0016874
39	0.07	0.865	2.31	0.12	0.98	3a9vA	GO:0000166 GO:0003824 GO:0008152 GO:0016874
40	0.07	0.835	2.36	0.12	0.94	4dg8A	GO:0000166 GO:0003824 GO:0008152
41	0.07	0.860	1.93	0.11	0.95	5e7qA	GO:0003824 GO:0008152
42	0.07	0.864	2.10	0.10	0.96	3e7wA	GO:0000166 GO:0003824 GO:0005524 GO:0005737 GO:0008152 GO:0016874 GO:0016876 GO:0047473 GO:0070395
43	0.07	0.861	2.20	0.11	0.98	2d1sA	GO:0000166 GO:0003824 GO:0004497 GO:0005524 GO:0005777 GO:0008152 GO:0008218 GO:0016491 GO:0046872 GO:0047077 GO:0055114
44	0.07	0.874	2.23	0.12	0.98	3kxwA	GO:0003824 GO:0008152
45	0.07	0.831	2.38	0.13	0.95	4oxiA	GO:0003824 GO:0008152
46	0.07	0.854	2.71	0.16	0.99	3pbkA	GO:0003824 GO:0008152
47	0.07	0.836	2.41	0.12	0.94	4ir7A	GO:0003824 GO:0008152 GO:0016874
48	0.07	0.855	2.45	0.14	0.98	5d6jA	GO:0003824 GO:0008152 GO:0016874

Consensus prediction of GO terms

Molecular Function	GO:0005524	GO:0016879	GO:0043169	GO:0016208	GO:0003987
GO-Score	0.52	0.44	0.44	0.39	0.39
Biological Processes	GO:0018393	GO:0006113	GO:0016570	GO:0042330	GO:0042221	GO:0019427
GO-Score	0.44	0.44	0.44	0.44	0.44	0.39
Cellular Component	GO:0043231	GO:0012505	GO:0044444
GO-Score	0.44	0.44	0.44

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv3268

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]