I-TASSER results

I-TASSER results for job id Rv3238c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (244 residues)
MKRYLTIIYGAASYLVFLVAFGYAIGFVGDVVVPRTVDHAIAAPIGQAVVVNLVLLGVFA
VQHSVMARQGFKRWWTRFVPPSIERSTYVLLASVALLLLYWQWRTMPAVIWDVRQPAGRV
ALWALFWLGWATVLTSTFMINHFELFGLRQVYLAWRGKPYTEIGFQAHLLYRWVRHPIML
GFVVAFWATPMMTAGHLLFAIGATGYILVALQFEERDLLAALGDQYRDYRREVSMLLPWP
HRHT

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 \| \| \| \| \| \| \| \| \| \| \| \| MKRYLTIIYGAASYLVFLVAFGYAIGFVGDVVVPRTVDHAIAAPIGQAVVVNLVLLGVFAVQHSVMARQGFKRWWTRFVPPSIERSTYVLLASVALLLLYWQWRTMPAVIWDVRQPAGRVALWALFWLGWATVLTSTFMINHFELFGLRQVYLAWRGKPYTEIGFQAHLLYRWVRHPIMLGFVVAFWATPMMTAGHLLFAIGATGYILVALQFEERDLLAALGDQYRDYRREVSMLLPWPHRHT
Prediction	CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHCCHCEHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHCCCCCCCC
Conf.Score	9768899999999999999999999997566676556777666668899999999999999988775789999999986757899999999999999999998478875898668756899999999999999999999868999889999998657777887667766344445868999999999999988889999999999999987788999999987999999998696657888889
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 \| \| \| \| \| \| \| \| \| \| \| \| MKRYLTIIYGAASYLVFLVAFGYAIGFVGDVVVPRTVDHAIAAPIGQAVVVNLVLLGVFAVQHSVMARQGFKRWWTRFVPPSIERSTYVLLASVALLLLYWQWRTMPAVIWDVRQPAGRVALWALFWLGWATVLTSTFMINHFELFGLRQVYLAWRGKPYTEIGFQAHLLYRWVRHPIMLGFVVAFWATPMMTAGHLLFAIGATGYILVALQFEERDLLAALGDQYRDYRREVSMLLPWPHRHT
Prediction	6420000111330221132233333313333321322344343310201221133133113100100243014102422343110000021013102311310133320002043332322123333323323321023131021111220133245552564402331001211013121222333322233333222122133123101321144017423730450174041000234558
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHCCHCEHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHCCCCCCCC
MKRYLTIIYGAASYLVFLVAFGYAIGFVGDVVVPRTVDHAIAAPIGQAVVVNLVLLGVFAVQHSVMARQGFKRWWTRFVPPSIERSTYVLLASVALLLLYWQWRTMPAVIWDVRQPAGRVALWALFWLGWATVLTSTFMINHFELFGLRQVYLAWRGKPYTEIGFQAHLLYRWVRHPIMLGFVVAFWATPMMTAGHLLFAIGATGYILVALQFEERDLLAALGDQYRDYRREVSMLLPWPHRHT

4quvA

0.13

0.97

1.05

MUSTER

YDQLGPLLTVVNIFTFVFAGFLYFWGPFYDYFMGTALNYELHGTVTVPMLLVVGFQSFYLIDYFIHEEAVLTTWDIKHEKFGWMLCWGDLVWLPFTYTLQAQYLVHHTH----LPVWGIIAIVALNLAGYAIFRGANIQKHHFRRDPNRIVWGKPAKKTKQGSLLLTSGWWGIARHMNYFGDLMIALSWCLPAPIPYFHIVYFTILLLHREKRDDAMCLAKYGEDWLQYRKKVPRIVPKIY---

4a2nB

0.11

0.08

0.77

1.28

dPPAS

-----------------------------------------MNENLWKICFIVMFIIWVFVRKVYGTRAMKNKSKKKVRPNFEKSLVFLNFIGMVFLPLTAVFSSYLDSFNINLPDSIRLFALIVTFLNIGLFTKIHKDLGN---------NWSAILEIKDGHKLVKEGIYKNIRHAHLWLWVITQGIILSNWVVLIFGIVAWAILYFIRVPKEEELLIEEFGDEYIEYMGKTGRLFPK-----

4a2nB

0.14

0.11

0.77

3.30

wdPPAS

------------------------------------------MNENLWKICFIVMFIIWVFVRKVYGTRAMKNKSKKKVRPNFEKSLVFLNFIGMVFLPLTAVFSSYLDSFNINLP------DSIRLFALIVTFLNIGLFTKIHKDLGN--NWSAILEIKDGHKLVKEGIYKNIRHPMYAHLWLWVITQGIILWVVLIFGIVAWAILYFIRVPKEEELLIEE-DEYIEYMGKTGRLFPK-----

4quvA

0.12

0.97

1.38

wMUSTER

YDQLGPLLTVVNIFTFVFAGFLYFWGPFYDYFMGTALN-ELHGTVTVPMLLVVGFQSFYLIDYFIH-EEAVLTTWDIKHEKFGWMLCWGDLVWLPFTYTLQAQYLVHHTH---LPVWGIIAIVALNLAGYAIFRGANIQKHHFRRDPNRIVWGKPAKKTKQGSLLLTSGWWGIARHMNYFGDLMIALSWCLPAPIPYFHIVYFTILLLHREKRDDAMCLAKYGEDWLQYRKKVPRIVPKIY---

4a2nB

0.14

0.11

0.77

3.75

wPPAS

------------------------------------------MNENLWKICFIVMFIIWVFVRKVYGTRAMKNKSKKKVRPNFEKSLVFLNFIGMVFLPLTAVFSSYLDSFNINLP------DSIRLFALIVTFLNIGLFTKIHKDLGNNWSA--ILEIKDGHKLVKEGIYKNIRHPMYAHLWLWVITQGIILWVVLIFGIVAWAILYFIRVPKEEELLIEE-DEYIEYMGKTGRLFP---K--

4a2nB

0.10

0.08

0.77

3.10

dPPAS2

-----------------------------------------MNENLWKICFIVMFIIWVFVRKVYGTRAMKNKSKKKVRPNFEKSLVFLNFIGMVFLPLTAVFSSYLDSFNINLPDSIRLFALIVTFLNIGLFTKIHKDLGN---------NWSAILEIKDGHKLVKEGIYKNIRHMYAHLWLWVITQGIILWVVLIFGIVAWAILYFIRVPKEEELLIEEFGDEYIEYMGKTGRLFPK-----

4a2nB

0.09

0.07

0.77

2.33

PPAS

-----------------------------------------MNENLWKICFIVMFIIWVFVRKVYGTRAMKNKSKKKVRPNFEKSLVFLNFIGMVFLPLTAVFSSYLDSFNINLP-------DSIRLFALIVTFLNIGLFTKIHKDLGNNWSA--ILEIKDGHKLVKEGIYKNIRHMYAHLWLWVITQGIILWVVLIFGIVAWAILYFIRVPKEEELLIEEFGDEYIEYMGKTGRLFPK-----

4a2nB

0.09

0.07

0.77

2.54

Env-PPAS

-----------------------------------------MNENLWKICFIVMFIIWVFVRKVYGTRAMKNKSKKKVRPNFEKSLVFLNFIGMVFLPLTAVFSSYLDSFNINLP-------DSIRLFALIVTFLNIGLFTKIHKDLGNNWSAILE--IKDGHKLVKEGIYKNIRHMYAHLWLWVITQGIILWVVLIFGIVAWAILYFIRVPKEEELLIEEFGDEYIEYMGKTGRLFPK-----

4a2nB

0.10

0.07

0.77

1.02

MUSTER

MN---ENLWKICFIVMFIIWVFVRKVYGTRAMKNKSKKKVRPNFEKSLVFLNFIGMVFLPLTAVFSS------------------------------YLDSFNINLP---------------DSIRLFALIVTFLNIGLFTKIHKDLGNNWSAILE--IKDGHKLVKEGIYKNIRHMYAHLWLWVITQGIILWVVLIFGIVAWAILYFIRVPKEEELLIEEFGDEYIEYMGKTGRLFPK-----

4quvA2

0.18

0.09

0.52

0.98

dPPAS

-----------------------------------------------------------------------------------------------------------------LPVWGIIAIVALNLAGYAIFRGANIQKHHFRRDPNRIVWGKPAKKTKQGSLLLTSGWWGIARHMNYFGDLMIALSWCLPAPIPYFHIVYFTILLLHREKRDDAMCLAKYGEDWLQYRKKVPRIVPKIY---

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-1.89

Estimated TM-score = 0.49±0.15

Estimated RMSD = 10.0±4.6Å

Download Model 2

C-score=-2.13

Download Model 3

C-score=-3.11

Download Model 4

C-score=-3.24

Download Model 5

C-score=-3.07

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	4quvA	0.822	2.95	0.126	0.975
2	4a2nB	0.592	3.36	0.118	0.717
3	4djiA	0.494	4.67	0.097	0.709
4	5ek8A	0.490	5.60	0.051	0.799
5	3rkoN	0.485	5.28	0.091	0.750
6	4he8L	0.483	5.21	0.069	0.750
7	5i6xA	0.481	4.99	0.063	0.713
8	3rkoL	0.479	5.24	0.068	0.750
9	1rsrB	0.476	5.51	0.057	0.754
10	4y9jA	0.474	5.75	0.054	0.775

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.07	3	2z1qA	FAD	Rep, Mult	182,185,186,204,207
2	0.06	2	4quvA	NDP	Rep, Mult	72,137,140,144,164,165,166,171,176,178,179,214,218,221,222,226,229
3	0.05	2	1k6lH	CDL	Rep, Mult	199,206
4	0.05	2	3ajoA	MG	Rep, Mult	212,215
5	0.02	1	1rsrB	UUU	Rep, Mult	93,97,186,188,196,199
6	0.02	1	4a2nB	SAH	Rep, Mult	147,151,152,155,158,159,163,165,166,171,176,214,218
7	0.02	1	3mkhA	FAD	Rep, Mult	119,121,187,188,189,199
8	0.02	1	3rkoN	LFA	Rep, Mult	129,132,133,136,183,184
9	0.02	1	4a2nB	CDL	Rep, Mult	134,138,142,145
10	0.02	1	3l1lA	ARG	Rep, Mult	61,66,67,129,130,133,134,137,181
11	0.02	1	2h61E	CA	Rep, Mult	234,237
12	0.02	1	1d4m1	MYR	Rep, Mult	223,224
13	0.02	1	1rsvA	AZI	Rep, Mult	94,97,186,203,206
14	0.02	1	1l0vO	MQ7	Rep, Mult	19,20
15	0.02	1	2nw8A	TRP	Rep, Mult	226,229

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	1xvgC	0.434	5.46	0.068	0.693	1.14.13.25	96,199
2	0.060	2bq1I	0.442	4.77	0.069	0.643	1.17.4.1	NA
3	0.060	1is2A	0.457	5.74	0.064	0.742	1.3.3.6	183,186
4	0.060	1biqB	0.474	5.47	0.061	0.750	1.17.4.1	NA
5	0.060	2iukB	0.415	6.74	0.054	0.787	1.13.11.12	NA
6	0.060	1prhA	0.439	5.52	0.032	0.709	1.14.99.1	NA
7	0.060	1mhyB	0.440	5.22	0.040	0.676	1.14.13.25	59,96,194
8	0.060	1bucA	0.434	5.36	0.043	0.672	1.3.99.2	129
9	0.060	1jk0A	0.436	4.62	0.059	0.623	1.17.4.1	NA
10	0.060	3b8cB	0.447	5.94	0.045	0.742	3.6.3.6	200,205,207
11	0.060	1aorB	0.462	5.92	0.058	0.787	1.2.7.5	178
12	0.060	1mhsA	0.466	5.74	0.046	0.754	3.6.3.6	NA
13	0.060	2fonB	0.452	5.80	0.048	0.742	1.3.3.6	51
14	0.060	3djlA	0.461	5.85	0.055	0.766	1.3.99.-	NA
15	0.060	1br2A	0.406	6.12	0.068	0.697	3.6.1.32	NA
16	0.060	1mhyD	0.442	5.37	0.075	0.693	1.14.13.25	NA
17	0.060	1ygeA	0.474	5.82	0.041	0.787	1.13.11.12	NA
18	0.060	2ix6A	0.454	5.35	0.059	0.697	1.3.3.6	NA
19	0.060	2jifA	0.436	5.42	0.044	0.668	1.3.99.-	129

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.28	0.822	2.95	0.13	0.98	4quvA	GO:0000166 GO:0006696 GO:0016020 GO:0016021 GO:0016126 GO:0016491 GO:0016628 GO:0050613 GO:0050661 GO:0055114
1	0.21	0.592	3.36	0.12	0.72	4a2nB	GO:0004671 GO:0006481 GO:0016020 GO:0016021
2	0.07	0.494	4.67	0.10	0.71	4djiA	GO:0003333 GO:0005886 GO:0005887 GO:0006810 GO:0006865 GO:0015171 GO:0015179 GO:0015297 GO:0015807 GO:0016020 GO:0016021 GO:0051454 GO:1902475
3	0.07	0.483	5.20	0.07	0.75	4he8F	GO:0005886 GO:0008137 GO:0016020 GO:0016021 GO:0016491 GO:0042773 GO:0048038 GO:0055114
4	0.07	0.490	5.60	0.05	0.80	5ek8A	GO:0016702 GO:0046872 GO:0055114
5	0.07	0.445	5.86	0.07	0.74	5fnoA	GO:0005576 GO:0016491 GO:0016702 GO:0046872 GO:0050584 GO:0051213 GO:0055114
6	0.07	0.445	5.53	0.07	0.73	4he8G	GO:0005886 GO:0008137 GO:0016020 GO:0016021 GO:0016491 GO:0042773 GO:0048038 GO:0055114
7	0.07	0.419	6.77	0.07	0.80	2iujA	GO:0006633 GO:0016491 GO:0016702 GO:0031408 GO:0046872 GO:0051213 GO:0055114
8	0.07	0.448	5.67	0.03	0.73	1no3A	GO:0005737 GO:0006629 GO:0006631 GO:0006633 GO:0016491 GO:0016702 GO:0031408 GO:0046872 GO:0051213 GO:0055114
9	0.07	0.477	5.40	0.04	0.77	2iukA	GO:0005737 GO:0006629 GO:0006631 GO:0006633 GO:0016491 GO:0016702 GO:0031408 GO:0046872 GO:0051213 GO:0055114
10	0.07	0.444	5.43	0.08	0.70	4he8I	GO:0005886 GO:0006810 GO:0008137 GO:0016020 GO:0016021 GO:0016491 GO:0042773 GO:0048038 GO:0050136 GO:0055114
11	0.07	0.443	5.65	0.02	0.73	3vf1A	GO:0005506 GO:0016491 GO:0016702 GO:0046872 GO:0051213 GO:0055114
12	0.07	0.442	5.64	0.04	0.70	4nreA	GO:0005506 GO:0005509 GO:0005622 GO:0005634 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0006629 GO:0006915 GO:0008285 GO:0008289 GO:0010744 GO:0016020 GO:0016165 GO:0016491 GO:0016702 GO:0019369 GO:0019372 GO:0019898 GO:0030336 GO:0030850 GO:0030856 GO:0035360 GO:0036403 GO:0043651 GO:0045618 GO:0045786 GO:0045926 GO:0046872 GO:0050473 GO:0051122 GO:0051213 GO:0055114 GO:0070062 GO:0090197
13	0.07	0.438	5.77	0.05	0.72	3rdeA	GO:0001503 GO:0002820 GO:0004052 GO:0005506 GO:0005546 GO:0005737 GO:0005811 GO:0005829 GO:0005886 GO:0006629 GO:0006631 GO:0006646 GO:0008289 GO:0010811 GO:0016020 GO:0016491 GO:0016702 GO:0019369 GO:0019372 GO:0030282 GO:0030838 GO:0031234 GO:0034976 GO:0035358 GO:0035963 GO:0042060 GO:0043277 GO:0043651 GO:0046872 GO:0050473 GO:0051213 GO:0055114 GO:0070374 GO:0071277 GO:1901074 GO:2001303
14	0.06	0.420	5.05	0.06	0.66	3lrbA	GO:0003333 GO:0005886 GO:0006810 GO:0006865 GO:0015171 GO:0015297 GO:0016020 GO:0016021
15	0.06	0.452	4.36	0.05	0.63	3ob6B	GO:0003333 GO:0005886 GO:0005887 GO:0006810 GO:0006865 GO:0015171 GO:0015179 GO:0015181 GO:0015297 GO:0015807 GO:0016020 GO:0016021 GO:0051454 GO:1902475 GO:1903826
16	0.06	0.462	5.10	0.05	0.68	3gi9C	GO:0003333 GO:0005886 GO:0005887 GO:0015171 GO:0015179 GO:0015297 GO:0015807 GO:0016020 GO:0016021 GO:1902475
17	0.06	0.427	5.71	0.05	0.71	2p0mA	GO:0001503 GO:0002820 GO:0004052 GO:0005506 GO:0005546 GO:0005737 GO:0005811 GO:0005829 GO:0005886 GO:0006629 GO:0006631 GO:0006646 GO:0008289 GO:0010811 GO:0016020 GO:0016491 GO:0016702 GO:0019369 GO:0019372 GO:0030282 GO:0030838 GO:0031234 GO:0034976 GO:0035358 GO:0035963 GO:0042060 GO:0043277 GO:0043651 GO:0046872 GO:0050473 GO:0051122 GO:0051213 GO:0055114 GO:0070374 GO:0071277 GO:1901074 GO:2001303
18	0.06	0.474	5.82	0.04	0.79	1ygeA	GO:0005737 GO:0006629 GO:0006631 GO:0006633 GO:0016165 GO:0016491 GO:0016702 GO:0031408 GO:0046872 GO:0051213 GO:0055114

Consensus prediction of GO terms

Molecular Function	GO:0000166	GO:0050662	GO:0016627	GO:0008757	GO:0003880
GO-Score	0.57	0.57	0.57	0.42	0.42
Biological Processes	GO:0016126	GO:1902653	GO:0016129	GO:0044108	GO:0008204	GO:0097384	GO:0018410	GO:0006479	GO:0055114
GO-Score	0.57	0.57	0.57	0.57	0.57	0.57	0.42	0.42	0.38
Cellular Component	GO:0016021
GO-Score	0.51

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.