I-TASSER results

Input Sequence in FASTA format

>protein (186 residues)
MALGAVATAVIINSGDSTSTKAIVGAPAPRTVISTSPRPTAPTSTSPHPSPSTLRPQLPP
ETVTTVAPPGTGPTTVPTRTPTAAPPQTAVPPPAPLNPRTVVYRVTGTKQLFDLVNVVYT
DARGFPVTDFNVSLPWTKMVVLNPGVQTESVVATSLYSRLNCSIVNTGAQTVVASTNNAI
IATCTR

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 \| \| \| \| \| \| \| \| \| MALGAVATAVIINSGDSTSTKAIVGAPAPRTVISTSPRPTAPTSTSPHPSPSTLRPQLPPETVTTVAPPGTGPTTVPTRTPTAAPPQTAVPPPAPLNPRTVVYRVTGTKQLFDLVNVVYTDARGFPVTDFNVSLPWTKMVVLNPGVQTESVVATSLYSRLNCSIVNTGAQTVVASTNNAIIATCTR
Prediction	CCEEHHHHEEEEHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEHCCCCCCCCCCCCCEEEHCCCCCCCCCCCEEHCCCEEEEHCCCCCCCEEEEEEHCCCEEEEEEHCCCEEEEEHCCCCCEEEHCC
Conf.Score	833355444555378998888888899998888999999999999999999999999999999999999999999999999999999999999999988655567888888887758997799987554547756656898578887665899986685689999779779987479986567669
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 \| \| \| \| \| \| \| \| \| MALGAVATAVIINSGDSTSTKAIVGAPAPRTVISTSPRPTAPTSTSPHPSPSTLRPQLPPETVTTVAPPGTGPTTVPTRTPTAAPPQTAVPPPAPLNPRTVVYRVTGTKQLFDLVNVVYTDARGFPVTDFNVSLPWTKMVVLNPGVQTESVVATSLYSRLNCSIVNTGAQTVVASTNNAIIATCTR
Prediction	410000000010223454444443444445544454554544464545455454565444644445445664444444445564444445644444534321131335444243020010237434424220202133404044644343120112344030202245244214445423333158
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180

                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCEEHHHHEEEEHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEHCCCCCCCCCCCCCEEEHCCCCCCCCCCCEEHCCCEEEEHCCCCCCCEEEEEEHCCCEEEEEEHCCCEEEEEHCCCCCEEEHCC
MALGAVATAVIINSGDSTSTKAIVGAPAPRTVISTSPRPTAPTSTSPHPSPSTLRPQLPPETVTTVAPPGTGPTTVPTRTPTAAPPQTAVPPPAPLNPRTVVYRVTGTKQLFDLVNVVYTDARGFPVTDFNVSLPWTKMVVLNPGVQTESVVATSLYSRLNCSIVNTGAQTVVASTNNAIIATCTR

5dfzB

0.11

0.99

0.95

MUSTER

VALRGYVIRTARVMAANPNLKNVFVQLEPTSYHMHSPNHGLKDNANVKPERKVVVSNSYEGDVESIEKSTFKILPPLRDYKEFGPIQEIVRSPNMGNLRGKLIATLMENEPNSITSSAVSPGETPTGSDQGVIKIWNLK-EIIVGEVYSSSLTYDCSSTVTQITMIPNFDAFAVSSKDGQVNHYQQ

1mv3A

0.10

0.97

1.17

dPPAS

-----DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEG

2lw3A

0.18

0.08

0.46

1.80

wdPPAS

--------------------------------------------------------------------------------------------------MHLTYEIFGP--PGTVADISYFDVNSEPQRVDGAVLPWSLHITTNDAAVMGNIVAQGNSDSIGCRITV-DGKVRAERVSNEAYTYCLV

5dfzB

0.11

0.99

1.13

wMUSTER

VALRGYVIRTARVMAANPNLKNVFVQLEPTSYHMHSPNHGLKDNANVKPERKVVVSNSYEGDVESIEK-TFKILPPLRDYKEFGPIQEIVRSPNMGNLRGKLIATLMENEPNSITSSAVSPGETPTGSDQGVIKIWNLK-EIIVGEVYSSSLTYDCSSTVTQITMIPNFDAFAVSSKDGQVNHYQQ

2lw3A

0.18

0.08

0.46

2.05

wPPAS

--------------------------------------------------------------------------------------------------MHLTYEIFGP--PGTVADISYFDVNSEPQRVDGAVLPWSLHITTNDAAVMGNIVAQGNSDSIGCRITV-DGKVRAERVSNEAYTYCLK

2lw3A

0.18

0.08

0.46

1.86

dPPAS2

--------------------------------------------------------------------------------------------------MHLTYEIFGP--PGTVADISYFDVNSEPQRVDGAVLPWSLHITTNDAAVMGNIVAQGNSDSIGCRITV-DGKVRAERVSNEAYTYCLV

1mv3A

0.11

0.10

0.91

1.54

PPAS

---------------DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEPAAGAQEPGETAASEAAS-AVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATD-ELQLKAGDVVLVIPFQNPMGVKES

2lw3A

0.18

0.08

0.46

1.56

Env-PPAS

--------------------------------------------------------------------------------------------------MHLTYEIFGP--PGTVADISYFDVNSEPQRVDGAVLPWSLHITTNDAAVMGNIVAQGNSDSIGCRITV-DGKVRAERVSNEAYTYCLV

4nl6A

0.11

0.09

0.87

0.86

MUSTER

REEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKSDNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPIC-PDSLDDADALGSMLISWY-----MSGYHTGYMGFRQNQKEGRCSHSLN-------------------

3jbmA

0.11

0.09

0.82

0.81

dPPAS

SGMSRISQAVLPAGTGTDGYVVVDATIVPDLLPRLGHAARIFQRYAVETLEFEIQPMCPANTGGLPDPTDNDHTFDALQATRGAVVAKWWESRTVRPQYTRTLLWTSSGKEQRLTSILLCVGNNTDVVNVSVLCRWSVRLSVPSLETPEETTA---------------------------------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-3.16

Estimated TM-score = 0.36±0.12

Estimated RMSD = 12.6±4.3Å

Download Model 2

C-score=-3.15

Download Model 3

C-score=-4.86

Download Model 4

C-score=-4.91

Download Model 5

C-score=-5.00

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	5dfzB	0.834	2.86	0.110	0.962
2	1hn0A	0.490	5.33	0.047	0.850
3	3greA1	0.482	3.59	0.115	0.602
4	3iytA	0.471	4.98	0.045	0.758
5	5a5uB	0.443	5.23	0.085	0.731
6	2q1fA	0.438	5.21	0.064	0.753
7	3ibjA	0.420	6.10	0.045	0.796
8	5fshA	0.419	5.02	0.030	0.667
9	4r5oA	0.419	4.80	0.059	0.650
10	1rw9A	0.412	5.26	0.047	0.699

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.07	3	3v4pA	CA	Rep, Mult	113,121,123,125,129
2	0.05	2	3ko2B	CA	Rep, Mult	15,16
3	0.05	2	2iwkA	IOD	Rep, Mult	116,161,162,177
4	0.05	2	2pltA	CA	Rep, Mult	135,138
5	0.02	1	1kyaA	CU	Rep, Mult	116,162,164
6	0.02	1	4di0A	FE	Rep, Mult	35,39
7	0.02	1	3pddA	CA	Rep, Mult	129,131,135
8	0.02	1	4eneA	DMU	Rep, Mult	6,10
9	0.02	1	2c11D	FUL	Rep, Mult	87,168
10	0.02	1	3i9dW	MG	Rep, Mult	43,46
11	0.02	1	2v8vD	URP	Rep, Mult	107,131
12	0.02	1	1hw9A	ADP	Rep, Mult	103,131
13	0.02	1	2z6iB	CA	Rep, Mult	9,12
14	0.02	1	3sfzA	GBL	Rep, Mult	130,131,160,162
15	0.02	1	1a34A	U	Rep, Mult	106,107
16	0.02	1	5ezmA	MPG	Rep, Mult	2,5

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	1ri6A	0.365	4.14	0.057	0.511	3.1.1.31	NA
2	0.060	2madH	0.380	4.97	0.053	0.608	1.4.99.3	113
3	0.060	1n1hA	0.291	6.10	0.040	0.538	2.7.7.48	NA
4	0.060	1cb8A	0.328	5.88	0.040	0.624	4.2.2.5	186
5	0.060	3l4uA	0.372	5.33	0.034	0.656	3.2.1.20,3.2.1.3	112
6	0.060	1hn0A	0.490	5.33	0.047	0.850	4.2.2.20	NA
7	0.060	2z8yP	0.363	4.97	0.039	0.597	2.3.1.169	NA
8	0.060	1gthA	0.324	6.34	0.051	0.645	1.3.1.2	154
9	0.060	2ajtA	0.368	5.66	0.031	0.667	5.3.1.4	NA
10	0.060	2j62A	0.259	5.34	0.033	0.430	3.2.1.52	NA
11	0.060	3ecqB	0.365	5.51	0.053	0.634	3.2.1.97	NA
12	0.060	2vumA	0.392	5.82	0.046	0.720	2.7.7.6	NA
13	0.060	1j0mA	0.369	4.93	0.053	0.602	4.2.2.12	NA
14	0.060	2wanA	0.375	5.22	0.068	0.624	3.2.1.41	154
15	0.060	2zxqA	0.395	5.23	0.063	0.688	3.2.1.97	113
16	0.060	1i8qA	0.367	5.65	0.028	0.672	4.2.2.1	134
17	0.060	2q1fA	0.438	5.21	0.064	0.753	4.2.2.21	NA
18	0.060	1rw9A	0.412	5.26	0.047	0.699	4.2.2.5	116
19	0.060	2pmzQ	0.291	5.47	0.023	0.521	2.7.7.6	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.17	0.834	2.86	0.11	0.96	5dfzB	GO:0000011 GO:0000166 GO:0004672 GO:0004674 GO:0005524 GO:0005643 GO:0005768 GO:0005770 GO:0005794 GO:0006468 GO:0006623 GO:0006810 GO:0006914 GO:0010008 GO:0015031 GO:0016020 GO:0016236 GO:0016301 GO:0016310 GO:0016740 GO:0030242 GO:0032968 GO:0034271 GO:0034272 GO:0043130 GO:0045053 GO:0045324 GO:0048017 GO:0071561
1	0.06	0.393	4.55	0.05	0.57	2h9lA	GO:0000123 GO:0001501 GO:0005622 GO:0005634 GO:0005654 GO:0005671 GO:0006351 GO:0006355 GO:0016568 GO:0018024 GO:0031175 GO:0035064 GO:0035097 GO:0035948 GO:0042800 GO:0043966 GO:0043981 GO:0043982 GO:0043984 GO:0043995 GO:0043996 GO:0044666 GO:0046972 GO:0048188 GO:0051568 GO:0071339
2	0.06	0.371	4.40	0.04	0.54	4j0xB	GO:0000154 GO:0005634 GO:0005654 GO:0005730 GO:0006364 GO:0030515 GO:0030529 GO:0031167 GO:0031428 GO:0032040 GO:0042254
3	0.06	0.383	5.44	0.04	0.68	3sfzA	GO:0000166 GO:0001666 GO:0001843 GO:0005524 GO:0005634 GO:0005737 GO:0005829 GO:0006915 GO:0006919 GO:0007275 GO:0007420 GO:0007568 GO:0007584 GO:0008635 GO:0008656 GO:0010659 GO:0030154 GO:0030900 GO:0031072 GO:0034349 GO:0042802 GO:0042981 GO:0043293 GO:0043531 GO:0051260 GO:0051402 GO:0070059 GO:0070062 GO:0071560 GO:0097190 GO:1902510 GO:2001235
4	0.06	0.366	4.25	0.06	0.51	3ow8C	GO:0005634 GO:0005654 GO:0005737 GO:0006351 GO:0006355 GO:0016055 GO:0016593 GO:0032968 GO:0035327 GO:0045638 GO:0045944 GO:0051571 GO:0055087 GO:0080182 GO:2001162
5	0.06	0.340	4.01	0.07	0.47	4v6iAa	GO:0001403 GO:0001965 GO:0004871 GO:0005092 GO:0005737 GO:0007186 GO:0010255 GO:0017148 GO:0022627 GO:0050790 GO:2001125
6	0.06	0.349	4.33	0.05	0.49	1b9xA	GO:0001750 GO:0003924 GO:0004871 GO:0005622 GO:0005765 GO:0005834 GO:0007165 GO:0007186 GO:0007191 GO:0007200 GO:0008283 GO:0016020 GO:0016056 GO:0022400 GO:0032403 GO:0043209 GO:0050909 GO:0051020 GO:0060041 GO:0070062 GO:0071380 GO:0071870 GO:0097381 GO:1903561
7	0.06	0.361	4.38	0.04	0.51	5em2A	GO:0000463 GO:0000466 GO:0005634 GO:0005654 GO:0005730 GO:0006364 GO:0030687 GO:0042254 GO:0042273 GO:0043021
8	0.06	0.365	4.20	0.07	0.50	4u7aA	GO:0000463 GO:0000466 GO:0005634 GO:0005654 GO:0005730 GO:0006364 GO:0030687 GO:0042254 GO:0042273 GO:0043021 GO:0070180 GO:0070545
9	0.06	0.331	4.00	0.08	0.46	5a1uD	GO:0000139 GO:0005198 GO:0005737 GO:0005794 GO:0005829 GO:0006810 GO:0006886 GO:0006888 GO:0006890 GO:0006891 GO:0015031 GO:0016020 GO:0016192 GO:0030117 GO:0030126 GO:0030663 GO:0031410 GO:1901998
10	0.06	0.345	4.54	0.04	0.52	2ovqB	GO:0000209 GO:0001944 GO:0004842 GO:0005634 GO:0005654 GO:0005730 GO:0005737 GO:0005829 GO:0006974 GO:0007062 GO:0010868 GO:0010883 GO:0016032 GO:0016567 GO:0019005 GO:0030332 GO:0030674 GO:0031146 GO:0031398 GO:0031625 GO:0032876 GO:0032880 GO:0034644 GO:0042802 GO:0043234 GO:0045741 GO:0045746 GO:0050816 GO:0050821 GO:0051443 GO:0055088 GO:0070374 GO:0097027 GO:1901800 GO:1902806 GO:1903146 GO:1903378 GO:1903955 GO:1990452 GO:2000060 GO:2000346 GO:2000639
11	0.06	0.256	5.25	0.02	0.44	5ceiA	GO:0000166 GO:0004672 GO:0004674 GO:0004693 GO:0005524 GO:0005634 GO:0005654 GO:0006351 GO:0006355 GO:0006367 GO:0006468 GO:0008353 GO:0016301 GO:0016310 GO:0016592 GO:0016740 GO:0045944 GO:0051726
12	0.06	0.342	3.78	0.03	0.46	3jb9L	GO:0005634 GO:0005681 GO:0005682 GO:0006397 GO:0008380 GO:0045292
13	0.06	0.262	5.06	0.02	0.44	4azfA	GO:0000151 GO:0000166 GO:0000287 GO:0004672 GO:0004674 GO:0004712 GO:0004713 GO:0005524 GO:0005634 GO:0005654 GO:0005737 GO:0006468 GO:0006915 GO:0006974 GO:0007224 GO:0016301 GO:0016310 GO:0016740 GO:0018108 GO:0030145 GO:0030529 GO:0042771 GO:0043130 GO:0045725 GO:0051534 GO:1901796
14	0.06	0.229	5.37	0.06	0.38	3d9vA	GO:0000139 GO:0000166 GO:0001726 GO:0003383 GO:0004672 GO:0004674 GO:0005524 GO:0005737 GO:0005794 GO:0005814 GO:0005829 GO:0005856 GO:0005886 GO:0006468 GO:0006915 GO:0006921 GO:0006939 GO:0007159 GO:0007165 GO:0007249 GO:0007266 GO:0016020 GO:0016301 GO:0016310 GO:0016525 GO:0016740 GO:0017048 GO:0017049 GO:0022614 GO:0030027 GO:0030036 GO:0030155 GO:0030866 GO:0032059 GO:0032060 GO:0032091 GO:0032956 GO:0032970 GO:0035509 GO:0035556 GO:0042995 GO:0043524 GO:0045616 GO:0046872 GO:0048010 GO:0048013 GO:0050900 GO:0050901 GO:0051451 GO:0051492 GO:0051493 GO:0051893 GO:0051894 GO:0090002 GO:1903140 GO:1903347 GO:2000114 GO:2000145
15	0.06	0.299	5.56	0.04	0.52	2i6lA	GO:0000165 GO:0000166 GO:0004672 GO:0004674 GO:0004707 GO:0005524 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0006468 GO:0007049 GO:0007165 GO:0016301 GO:0016310 GO:0016740 GO:0019901 GO:0046982
16	0.06	0.298	6.25	0.05	0.58	3pvuA	GO:0000166 GO:0002029 GO:0002031 GO:0003108 GO:0004672 GO:0004674 GO:0004703 GO:0005524 GO:0005737 GO:0005829 GO:0005886 GO:0006468 GO:0006886 GO:0007165 GO:0007186 GO:0007213 GO:0009966 GO:0016020 GO:0016301 GO:0016310 GO:0016740 GO:0018105 GO:0031694 GO:0031755 GO:0045988 GO:0047696 GO:0060048
17	0.06	0.301	5.52	0.04	0.54	1blxA	GO:0000082 GO:0000166 GO:0000307 GO:0001726 GO:0001954 GO:0002244 GO:0003323 GO:0004672 GO:0004674 GO:0004693 GO:0005524 GO:0005634 GO:0005654 GO:0005737 GO:0005813 GO:0005815 GO:0005829 GO:0005856 GO:0006468 GO:0007049 GO:0007050 GO:0007219 GO:0008285 GO:0009615 GO:0010468 GO:0010628 GO:0014002 GO:0016301 GO:0016310 GO:0016740 GO:0021542 GO:0021670 GO:0030097 GO:0030154 GO:0030332 GO:0033077 GO:0042063 GO:0042127 GO:0042995 GO:0043697 GO:0045596 GO:0045638 GO:0045646 GO:0045656 GO:0045668 GO:0045786 GO:0048146 GO:0048699 GO:0050680 GO:0051301 GO:0060218 GO:1904628 GO:2000145 GO:2000773
18	0.06	0.303	5.35	0.03	0.51	3nr9B	GO:0000166 GO:0004672 GO:0004674 GO:0004712 GO:0004713 GO:0005524 GO:0005634 GO:0005654 GO:0006468 GO:0010033 GO:0010212 GO:0016301 GO:0016310 GO:0016607 GO:0016740 GO:0018108 GO:0032526 GO:0043484 GO:0045721 GO:0046777

Consensus prediction of GO terms

Molecular Function	GO:0032550	GO:0035639	GO:0032559	GO:0016773	GO:0032182	GO:0016301
GO-Score	0.45	0.45	0.45	0.35	0.35	0.35
Biological Processes	GO:0034243	GO:0045944	GO:0032786	GO:0006796	GO:0007033	GO:0034067	GO:0035556	GO:0006914	GO:0016197	GO:0006464	GO:0072666	GO:0048308	GO:0007031	GO:0032507	GO:0006605
GO-Score	0.45	0.45	0.45	0.35	0.35	0.35	0.35	0.35	0.35	0.35	0.35	0.35	0.35	0.35	0.35
Cellular Component	GO:0031981	GO:0005774	GO:0044440	GO:0035032	GO:0005635	GO:0044232
GO-Score	0.36	0.35	0.35	0.35	0.35	0.35

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv3209

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]