Threading Zmax Znorm MUSTER 4.51 0.78 dPPAS 6.78 0.73 wdPPAS 10.40 1.12 wMUSTER 6.16 1.06 wPPAS 10.83 1.55 dPPAS2 13.78 1.31 PPAS 9.29 1.33 Env-PPAS 9.93 1.24 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=2259) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -3.44 0.33+-0.11 15.6+-3.3 423 0.028 model2 -3.65 258 0.023 model3 -3.87 249 0.018 model4 -4.00 249 0.016 model5 -4.29 195 0.012 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).