Threading Zmax Znorm MUSTER 4.77 0.82 dPPAS 7.36 0.79 wdPPAS 6.07 0.65 wMUSTER 4.84 0.83 wPPAS 5.04 0.72 dPPAS2 11.27 1.07 PPAS 5.52 0.79 Env-PPAS 6.09 0.76 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=20200) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -1.79 0.50+-0.15 7.9+-4.4 13944 0.207 model2 -3.65 2341 0.032 model3 -4.61 847 0.012 model4 -4.00 1539 0.023 model5 -2.70 5167 0.083 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).