I-TASSER results

Input Sequence in FASTA format

>protein (145 residues)
MKLSNQKRHWPGYLFGRIRTSTLVLIAAFLAVWWIYETYRPQAPGPGDSPPTQVVPPGFV
PDPDYTWVPRTRVQPPTVKATPTTTSSTPPVSPPETTTDSAVPPPFELPPPFGPGTTTPT
PPAPLPQPGPGPTAGTYPKSEPPTR

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 \| \| \| \| \| \| \| MKLSNQKRHWPGYLFGRIRTSTLVLIAAFLAVWWIYETYRPQAPGPGDSPPTQVVPPGFVPDPDYTWVPRTRVQPPTVKATPTTTSSTPPVSPPETTTDSAVPPPFELPPPFGPGTTTPTPPAPLPQPGPGPTAGTYPKSEPPTR
Prediction	CCCCCCCCCCCCCCHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
Conf.Score	9888767776444344444478999999999998764568999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 \| \| \| \| \| \| \| MKLSNQKRHWPGYLFGRIRTSTLVLIAAFLAVWWIYETYRPQAPGPGDSPPTQVVPPGFVPDPDYTWVPRTRVQPPTVKATPTTTSSTPPVSPPETTTDSAVPPPFELPPPFGPGTTTPTPPAPLPQPGPGPTAGTYPKSEPPTR
Prediction	7535676441343123314232001131320111124426364454664444533444333636444345562553446454464775454644745574454454744444437454454545367744444446447665568
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140

                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCCCCCCCHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MKLSNQKRHWPGYLFGRIRTSTLVLIAAFLAVWWIYETYRPQAPGPGDSPPTQVVPPGFVPDPDYTWVPRTRVQPPTVKATPTTTSSTPPVSPPETTTDSAVPPPFELPPPFGPGTTTPTPPAPLPQPGPGPTAGTYPKSEPPTR

4nl6A

0.13

1.00

1.34

MUSTER

ASIDFKRETCVVVYTGREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKSDNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPICPDSLDDADALG

1mv3A

0.10

0.08

0.74

1.12

dPPAS

--------------------------------------DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEAAS

1mv3A

0.05

0.03

0.72

1.22

wdPPAS

-----------------------------------------DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASE

2w0cT

0.11

0.10

0.87

1.37

wMUSTER

--------------MANFLTKNFVWILAAGVGVWFYQKADNAAKTATKPIADFLAELQFLVNSNYVKFPNAGFVLTRDALQDDFIAYDDRI--KAWLGTHDRHKDFLAEILDHERRVKPVYRKLIGNIIDASTIRAASGVEL---

1mv3A

0.17

0.12

0.74

1.44

wPPAS

------------------------------------DG--SPAATPEIRVNHEPEPGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEPAAGAQEPGETAASEAASSSLPAVV

1mv3A

0.10

0.08

0.74

2.05

dPPAS2

--------------------------------------DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEAAS

1mv3A

0.10

0.08

0.74

1.61

PPAS

--------------------------------------DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEAAS

4hsrB1

0.14

1.00

0.62

Env-PPAS

GARDDSAAEGLRQMLGRMDASEVASAYNAFRRALTRLVTDRSGLEQAISHPFAAVAPGVSPQGQVWWAVPTLLRDDDAGMLKGWSWDQALSEALSVASQNLTGRSEHRPRFTHPLATQFPAWAGLLNPASRPINGLVPSAGPQAT

1zvoC

0.15

0.14

0.97

1.19

MUSTER

GTQSQPQRTFPEIQ-SYYMTSSQLSTPL----QWRQGEYKCVVQHTASKSKKEIFRWPESPKAQASSVPTAQPQAEGSLAKATTAPATTRNTGRGGEEKKKEKEKEEQEERETKTPECPSHTQPLGVYLLTPAVQDLWLRDKATF

3jbmA

0.13

0.12

0.94

1.05

dPPAS

VPDLLPRLGHAARIFQRYAVETLEFEI---------QPMCPANTGGGYVAGFLPDPTDNDHTFDALQATRGAVVAKWWESRTVRPQYTRTLLWTSSGKEQRLTSPGRLILLCVGNNTDVVNVSVLCRWSVRLSVPSLETPEETTA

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-3.56

Estimated TM-score = 0.32±0.11

Estimated RMSD = 13.0±4.2Å

Download Model 2

C-score=-4.15

Download Model 3

C-score=-4.48

Download Model 4

C-score=-4.55

Download Model 5

C-score=-5.00

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	1mv3A	0.634	1.90	0.085	0.731
2	2eflA	0.392	3.71	0.031	0.566
3	1b8tA	0.388	4.24	0.055	0.614
4	2zuoM2	0.384	4.90	0.034	0.641
5	4xbmB	0.374	4.34	0.015	0.593
6	1q5cA	0.371	4.53	0.057	0.614
7	2ch7A	0.366	3.96	0.022	0.552
8	2efkA	0.366	4.01	0.073	0.566
9	3b43A	0.365	4.52	0.068	0.600
10	5ca8A	0.354	4.56	0.028	0.579

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.09	4	4fe1F	CLA	Rep, Mult	25,29
2	0.07	3	4v1fA	BQ1	Rep, Mult	31,32,35
3	0.05	2	3e0dA	CA	Rep, Mult	62,64
4	0.05	2	3fbyA	CA	Rep, Mult	62,64,66,68,70,73,76
5	0.05	2	2efbA	UUU	Rep, Mult	131,133,134
6	0.02	1	2j5mA	MAN	Rep, Mult	81,83
7	0.02	1	4h2sC	PNS	Rep, Mult	20,21
8	0.02	1	2cixA	MAN	Rep, Mult	85,87
9	0.02	1	2wl3A	CA	Rep, Mult	63,107
10	0.02	1	3pcaM	DHB	Rep, Mult	61,68
11	0.02	1	2wsc2	CLA	Rep, Mult	19,145
12	0.02	1	5er5A	ET	Rep, Mult	36,37
13	0.02	1	1lgb1	III	Rep, Mult	115,116,117,118,119,120,121,122,123,124,128,129,130,137,138
14	0.02	1	2w6dB	CPL	Rep, Mult	94,95,96,97,98

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	5r1rA	0.201	4.67	0.041	0.345	1.17.4.1	NA
2	0.060	1l1lA	0.234	3.54	0.014	0.331	1.17.4.2	NA
3	0.060	1ekjG	0.237	3.69	0.080	0.338	4.2.1.1	NA
4	0.060	1wd9A	0.190	3.96	0.047	0.283	3.5.3.15	NA
5	0.060	1mc0A	0.201	4.36	0.083	0.324	3.1.4.17	84
6	0.060	1n1hA	0.235	3.46	0.034	0.317	2.7.7.48	NA
7	0.060	2dewX	0.238	4.55	0.025	0.393	3.5.3.15	NA
8	0.060	3daxA	0.238	3.72	0.020	0.338	1.14.13.17	NA
9	0.060	2ofgX	0.257	3.97	0.016	0.372	3.6.3.5	NA
10	0.060	3b43A	0.365	4.52	0.068	0.600	2.7.11.1	131,133
11	0.060	2d4eC	0.239	4.17	0.063	0.359	1.2.1.60	NA
12	0.060	2pziA	0.256	3.86	0.103	0.393	2.7.11.1	NA
13	0.060	1eulA	0.204	5.06	0.022	0.379	3.6.3.8	NA
14	0.060	2q3zA	0.232	4.31	0.019	0.379	2.3.2.13	NA
15	0.060	1uxvA	0.233	4.32	0.077	0.352	1.2.1.9	129
16	0.060	1p1jA	0.234	4.07	0.019	0.365	5.5.1.4	NA
17	0.060	2vkzG	0.254	4.69	0.021	0.421	2.3.1.38,3.1.2.14	NA
18	0.060	1qrjB	0.239	3.28	0.033	0.324	3.1.26.4	129
19	0.060	3hz3A	0.238	4.91	0.056	0.421	2.4.1.5	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.07	0.634	1.90	0.09	0.73	1mv3A	GO:0005634 GO:0005737 GO:0006897 GO:0006997 GO:0007275 GO:0008283 GO:0015629 GO:0016020 GO:0016032 GO:0030018 GO:0030100 GO:0030154 GO:0030315 GO:0030424 GO:0031674 GO:0033268 GO:0042692 GO:0042802 GO:0043065 GO:0043194 GO:0045664 GO:0048156 GO:0048711 GO:0051015 GO:0060987 GO:0060988 GO:0070063 GO:0071156
1	0.06	0.165	4.80	0.01	0.26	2vgeA	GO:0000122 GO:0003215 GO:0003229 GO:0003714 GO:0005634 GO:0005654 GO:0005737 GO:0005913 GO:0006351 GO:0006355 GO:0006915 GO:0008134 GO:0009791 GO:0030054 GO:0031076 GO:0035264 GO:0042633 GO:0042802 GO:0045171 GO:0045597 GO:0048871 GO:0060048 GO:0098609 GO:0098641 GO:1901796
2	0.06	0.179	3.51	0.02	0.25	1agsA	GO:0004364 GO:0005737 GO:0005829 GO:0006749 GO:0008152 GO:0016740 GO:0030855 GO:0070062 GO:1901687
3	0.06	0.170	4.27	0.00	0.24	4a63B	GO:0002039 GO:0005070 GO:0005634 GO:0005654 GO:0005737 GO:0005739 GO:0006915 GO:0007049 GO:0007165 GO:0017124 GO:0042802 GO:0042981 GO:0045786 GO:0048471 GO:0051059 GO:0072332 GO:1900119 GO:1900740 GO:1901216 GO:1901796
4	0.06	0.134	4.41	0.09	0.21	2jt4A	GO:0000147 GO:0003779 GO:0005634 GO:0005737 GO:0005768 GO:0005856 GO:0005886 GO:0005938 GO:0006897 GO:0008092 GO:0010008 GO:0016020 GO:0030041 GO:0030479 GO:0030674 GO:0042802 GO:0043130
5	0.06	0.158	3.82	0.03	0.23	4igzA	GO:0005200 GO:0005634 GO:0005737 GO:0005886 GO:0005925 GO:0007015 GO:0007155 GO:0008093 GO:0008307 GO:0015629 GO:0016020 GO:0016324 GO:0016477 GO:0030018 GO:0030027 GO:0030054 GO:0042995 GO:0044822 GO:0046872 GO:0048471 GO:0061049
6	0.06	0.155	4.59	0.05	0.26	1griA	GO:0000165 GO:0005070 GO:0005088 GO:0005154 GO:0005168 GO:0005634 GO:0005654 GO:0005730 GO:0005737 GO:0005768 GO:0005794 GO:0005829 GO:0005886 GO:0005911 GO:0007173 GO:0007265 GO:0007267 GO:0007411 GO:0008180 GO:0008286 GO:0008543 GO:0009967 GO:0012506 GO:0014066 GO:0016020 GO:0016032 GO:0016303 GO:0017124 GO:0019901 GO:0019903 GO:0019904 GO:0030154 GO:0030838 GO:0031295 GO:0031623 GO:0036092 GO:0038095 GO:0038096 GO:0038128 GO:0042059 GO:0042770 GO:0042802 GO:0043408 GO:0043547 GO:0043560 GO:0044822 GO:0046854 GO:0046875 GO:0046934 GO:0048015 GO:0048646 GO:0050900 GO:0060670 GO:0070062 GO:0070436 GO:0071479 GO:2000379
7	0.06	0.146	4.54	0.09	0.23	1uffA	GO:0005070 GO:0005089 GO:0005509 GO:0005737 GO:0005813 GO:0006897 GO:0009967 GO:0030154 GO:0035023 GO:0043547 GO:0046872 GO:0070062 GO:1903861
8	0.06	0.137	4.39	0.09	0.22	4esrA	GO:0001738 GO:0001947 GO:0002092 GO:0005737 GO:0005813 GO:0005814 GO:0005829 GO:0005856 GO:0005911 GO:0005912 GO:0005929 GO:0007169 GO:0007417 GO:0010842 GO:0016192 GO:0030030 GO:0030054 GO:0030862 GO:0030902 GO:0031513 GO:0034613 GO:0035844 GO:0035845 GO:0036038 GO:0036064 GO:0039008 GO:0039023 GO:0042384 GO:0042802 GO:0042995 GO:0043066 GO:0045944 GO:0050795 GO:0060271 GO:0065001 GO:0070121 GO:0070986 GO:0071599 GO:0072372
9	0.06	0.140	3.97	0.09	0.21	2kbtA	GO:0005576 GO:0005618 GO:0009405 GO:0016020 GO:0019864
10	0.06	0.134	3.22	0.02	0.18	2yuoA	GO:0005096 GO:0005622 GO:0005737 GO:0005829 GO:0005921 GO:0006886 GO:0007049 GO:0007050 GO:0012505 GO:0017137 GO:0030695 GO:0031338 GO:0032483 GO:0032486 GO:0045732 GO:0048227 GO:0090630
11	0.06	0.132	3.63	0.04	0.19	2oi3A	GO:0000166 GO:0002376 GO:0002522 GO:0002758 GO:0004672 GO:0004713 GO:0004715 GO:0005102 GO:0005524 GO:0005634 GO:0005737 GO:0005764 GO:0005794 GO:0005829 GO:0005856 GO:0005884 GO:0005886 GO:0005901 GO:0005925 GO:0006468 GO:0006887 GO:0006909 GO:0006954 GO:0007155 GO:0007169 GO:0007229 GO:0007498 GO:0008284 GO:0008360 GO:0016020 GO:0016023 GO:0016032 GO:0016301 GO:0016310 GO:0016740 GO:0018108 GO:0019221 GO:0030054 GO:0030133 GO:0030154 GO:0030838 GO:0031234 GO:0031410 GO:0031663 GO:0038083 GO:0038096 GO:0042995 GO:0043066 GO:0043299 GO:0045087 GO:0045728 GO:0046777 GO:0050690 GO:0050727 GO:0050764 GO:0051090 GO:0060333 GO:0071801 GO:2000251
12	0.06	0.142	5.31	0.07	0.28	1x2qA	GO:0005654 GO:0005737 GO:0005768 GO:0005829 GO:0006810 GO:0006886 GO:0006914 GO:0015031 GO:0016020 GO:0016197 GO:0031901 GO:0033565 GO:0036258 GO:0042059 GO:0043231
13	0.06	0.119	3.48	0.00	0.17	2ed0A	GO:0003677 GO:0005737 GO:0005829 GO:0005856 GO:0006928 GO:0007010 GO:0008093 GO:0008154 GO:0016032 GO:0016477 GO:0016601 GO:0017124 GO:0018108 GO:0019900 GO:0030027 GO:0030175 GO:0031209 GO:0031625 GO:0032403 GO:0042995 GO:0048365 GO:0070064 GO:2000601
14	0.06	0.130	3.41	0.00	0.19	2i0nA	GO:0000166 GO:0000902 GO:0001891 GO:0003774 GO:0003779 GO:0005524 GO:0005737 GO:0005829 GO:0005856 GO:0006909 GO:0008017 GO:0009847 GO:0016020 GO:0016459 GO:0030048 GO:0030175 GO:0030898 GO:0031252 GO:0031589 GO:0043621 GO:0046847 GO:0051015
15	0.06	0.134	3.39	0.00	0.19	2drkA	GO:0000166 GO:0003774 GO:0005524 GO:0016459
16	0.06	0.126	4.64	0.11	0.21	2dl7A
17	0.06	0.126	4.61	0.05	0.21	1pnjA	GO:0001678 GO:0001953 GO:0005068 GO:0005158 GO:0005159 GO:0005168 GO:0005634 GO:0005737 GO:0005801 GO:0005829 GO:0005911 GO:0005942 GO:0005943 GO:0006468 GO:0006810 GO:0007162 GO:0007165 GO:0008134 GO:0008286 GO:0008625 GO:0008630 GO:0014065 GO:0015031 GO:0016020 GO:0019903 GO:0030183 GO:0030335 GO:0032760 GO:0032869 GO:0033120 GO:0034644 GO:0034976 GO:0035014 GO:0036312 GO:0042993 GO:0043066 GO:0043125 GO:0043548 GO:0043551 GO:0043559 GO:0043560 GO:0045671 GO:0045944 GO:0046326 GO:0046854 GO:0046935 GO:0046982 GO:0048009 GO:0050821 GO:0051492 GO:0051531 GO:0060396 GO:0090003 GO:0090004 GO:1900103 GO:1990578 GO:2001275
18	0.06	0.128	4.20	0.00	0.20	2k9gA	GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005911 GO:0005925 GO:0006897 GO:0006915 GO:0007010 GO:0007267 GO:0008360 GO:0016020 GO:0016477 GO:0017124 GO:0030054 GO:0030139 GO:0030659 GO:0031410 GO:0042059 GO:0043005 GO:0045202

Consensus prediction of GO terms

Molecular Function	GO:0005515
GO-Score	0.46
Biological Processes	GO:1901796	GO:0071156	GO:0048711	GO:0016032	GO:0045664	GO:0008283	GO:0030100	GO:0042692	GO:0060988	GO:0006997	GO:0006749	GO:0000147	GO:0098609	GO:0030041	GO:0035264	GO:1901216	GO:1901687	GO:0009791	GO:0003215	GO:0003229	GO:0000122	GO:0031076	GO:0060048	GO:1900119	GO:0030855	GO:1900740	GO:0042633	GO:0072332	GO:0048871
GO-Score	0.12	0.07	0.07	0.07	0.07	0.07	0.07	0.07	0.07	0.07	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06
Cellular Component	GO:0043231
GO-Score	0.46

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv3103c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]