Threading Zmax Znorm MUSTER 3.96 0.68 dPPAS 8.67 0.93 wdPPAS 9.54 1.03 wMUSTER 4.36 0.75 wPPAS 9.02 1.29 dPPAS2 8.87 0.84 PPAS 8.77 1.25 Env-PPAS 11.05 1.38 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=20200) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -0.79 0.61+-0.14 3.0+-2.2 16756 0.446 model2 -2.80 2281 0.059 model3 -2.42 3272 0.088 model4 -3.18 662 0.041 model5 -3.79 606 0.022 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).