Threading Zmax Znorm MUSTER 4.35 0.75 dPPAS 6.89 0.74 wdPPAS 6.65 0.72 wMUSTER 5.12 0.88 wPPAS 7.30 1.04 dPPAS2 12.17 1.16 PPAS 9.22 1.32 Env-PPAS 7.15 0.89 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=11034) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -1.57 0.52+-0.15 9.6+-4.6 7213 0.222 model2 -5.00 242 0.005 model3 -5.00 211 0.004 model4 -5.00 202 0.005 model5 -4.59 179 0.011 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).