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I-TASSER results for job id Rv3000

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

 Input Sequence in FASTA format
 Predicted Secondary Structure
 Predicted Solvent Accessibility
 Predicted Normalized B-facotr
 Top 10 threading templates used by I-TASSER
 Top 1 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)
 Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)


 Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)


  Ligand binding sites

Rank C-score Cluster
size
PDB
Hit
Lig
Name
Download
Complex
Ligand Binding Site Residues
10.81 169 3bk7A ADP Rep, Mult 15,20,40,41,42,43,44,45,46
20.27 50 3puzA MG Rep, Mult 45,86,145,146
30.08 24 2ixfB ATP Rep, Mult 119,120,121,122,123,124,125
40.01 2 2d2fA MG Rep, Mult 38,39,40,41,42,44
50.01 3 1mv5B ATP Rep, Mult 16,18
60.01 2 1xf9B MG Rep, Mult 31,172
70.00 2 5d3mA ANP Rep, Mult 40,41,44,45,86,181
80.00 1 2olkB AT4 Rep, Mult 164,167,182
90.00 1 2ixfC ATP Rep, Mult 116,117,118,119,121
100.00 2 1q12B ATP Rep, Mult 131,148,149,156,157,158,159
110.00 1 3gd7A B44 Rep, Mult 89,91
120.00 1 1r0zA ATP Rep, Mult 3,6,8,40,41,42,43,44,45,46,86
130.00 2 3gd7D B44 Rep, Mult 89,91,92,97

Download the all possible binding ligands and detailed prediction summary.
Download the templates clustering results.
(a)C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)Cluster size is the total number of templates in a cluster.
(c)Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column.
Mult is the complex structures with all potential binding ligands in the cluster.

  Enzyme Commission (EC) numbers and active sites

RankCscoreECPDB
Hit
TM-scoreRMSDaIDENaCovEC NumberActive Site Residues
10.3803fvqB0.8632.070.2090.9643.6.3.3089,133,155
20.2872awnB0.8412.330.1850.9643.6.3.1986,155
30.2422awnA0.7232.550.2050.8453.6.3.1940,145,186
40.0601fx0A0.5043.660.0730.6393.6.3.14NA
50.0602qi9D0.8122.340.1580.9223.6.3.3348,155,178
60.0603eiqD0.4904.050.0820.6713.6.4.1340,45
70.0601xdmY0.4675.080.0670.7314.1.2.13NA
80.0602oemB0.5064.880.0960.7725.3.2.-155
90.0601fbaA0.4915.150.0510.8044.1.2.13NA
100.0603i62A0.5014.510.1100.7263.6.4.1321,45,151
110.0601bxnA0.4995.060.0620.7764.1.1.39NA
120.0603gd7A0.7563.260.1370.9683.6.3.49,3.6.3.1948,156
130.0601bxnE0.4995.060.0620.7764.1.1.39NA
140.0603iceC0.5014.260.0820.6853.6.1.-126
150.0601skyB0.4913.930.0490.6533.6.3.14125
160.0602zrpA0.5033.810.0990.6533.4.99.3743,45,87,182
170.0602hldK0.4345.070.0920.6993.6.3.14NA
180.0603g61A0.8891.900.2100.9773.6.3.44NA
190.0602db3A0.4974.690.1060.7263.6.4.13NA
200.0601xfbA0.4795.120.0700.7674.1.2.13NA
210.0601r0zC0.7912.330.1850.9133.6.3.4920,38,41,43,45,50,146
220.0601xdmB0.4674.950.0560.7224.1.2.13NA

(a)CscoreEC is the confidence score for the EC number prediction. CscoreEC values range in between [0-1];
where a higher score indicates a more reliable EC number prediction.
(b)TM-score is a measure of global structural similarity between query and template protein.
(c)RMSDa is the RMSD between residues that are structurally aligned by TM-align.
(d)IDENa is the percentage sequence identity in the structurally aligned region.
(e)Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided
by length of the query protein.

  Gene Ontology (GO) terms

Homologous GO templates in PDB 
RankCscoreGOTM-scoreRMSDaIDENaCovPDB HitAssociated GO Terms
00.540.7912.480.190.901xmiC GO:0000166 GO:0005224 GO:0005254 GO:0005260 GO:0005524 GO:0005737 GO:0005765 GO:0005768 GO:0005769 GO:0005829 GO:0005886 GO:0006695 GO:0006810 GO:0006811 GO:0006821 GO:0006904 GO:0007585 GO:0009986 GO:0015106 GO:0015108 GO:0015701 GO:0016020 GO:0016021 GO:0016323 GO:0016324 GO:0016787 GO:0016887 GO:0017081 GO:0019869 GO:0019899 GO:0030165 GO:0030301 GO:0030660 GO:0031205 GO:0031901 GO:0034707 GO:0035774 GO:0042626 GO:0043225 GO:0043234 GO:0045921 GO:0048240 GO:0051454 GO:0055037 GO:0055085 GO:0060081 GO:0070062 GO:0071320 GO:1902161 GO:1902476 GO:1902943
10.510.7912.330.180.911r0zC GO:0000166 GO:0003254 GO:0005254 GO:0005260 GO:0005524 GO:0005737 GO:0005768 GO:0005769 GO:0005829 GO:0005886 GO:0006695 GO:0006810 GO:0006811 GO:0006821 GO:0006904 GO:0009986 GO:0015106 GO:0015108 GO:0015701 GO:0016020 GO:0016021 GO:0016324 GO:0016787 GO:0016887 GO:0019869 GO:0019899 GO:0030165 GO:0030301 GO:0031205 GO:0031901 GO:0034707 GO:0035774 GO:0042626 GO:0043234 GO:0045921 GO:0048240 GO:0051454 GO:0055037 GO:0055085 GO:0060081 GO:0070062 GO:0071320 GO:1902161 GO:1902476 GO:1902943
20.510.8342.530.160.971oxuA GO:0000166 GO:0005524 GO:0016887
30.490.8602.260.230.983b5wA GO:0000166 GO:0005319 GO:0005524 GO:0005886 GO:0006810 GO:0006869 GO:0008144 GO:0008289 GO:0015437 GO:0016020 GO:0016021 GO:0016787 GO:0016887 GO:0034040 GO:0042626 GO:0043190 GO:0055085 GO:1901264
40.480.8632.070.210.963fvqB GO:0000166 GO:0005524 GO:0005886 GO:0006810 GO:0006811 GO:0015408 GO:0015682 GO:0016020 GO:0016787 GO:0016887 GO:0043190 GO:0055072
50.470.8282.360.200.951mv5A GO:0000166 GO:0005524 GO:0005886 GO:0006810 GO:0006855 GO:0008559 GO:0016020 GO:0016021 GO:0016787 GO:0016887 GO:0042626 GO:0042908 GO:0046677 GO:0055085
60.460.8452.350.180.971b0uA GO:0000166 GO:0003333 GO:0005524 GO:0005886 GO:0006810 GO:0006865 GO:0015424 GO:0016020 GO:0016887
70.450.8882.040.200.982ghiA GO:0000166 GO:0005524 GO:0006810 GO:0016020 GO:0016021 GO:0016887 GO:0042626 GO:0055085
80.440.9061.750.230.984a82A GO:0000166 GO:0005524 GO:0005886 GO:0006810 GO:0016020 GO:0016021 GO:0016787 GO:0016887 GO:0042626 GO:0055085
90.440.8412.330.180.962awnB GO:0000166 GO:0005215 GO:0005524 GO:0005886 GO:0006810 GO:0008643 GO:0015423 GO:0015609 GO:0015768 GO:0016020 GO:0016787 GO:0016820 GO:0016887 GO:0031234 GO:0033613 GO:0042956 GO:0043190 GO:0055085 GO:1990060
100.440.8871.960.210.982ixfA GO:0000166 GO:0002250 GO:0002376 GO:0002481 GO:0002485 GO:0002489 GO:0002591 GO:0005524 GO:0005783 GO:0005789 GO:0006810 GO:0015031 GO:0015197 GO:0015433 GO:0015440 GO:0015833 GO:0016020 GO:0016021 GO:0016887 GO:0019885 GO:0030176 GO:0042270 GO:0042287 GO:0042288 GO:0042605 GO:0042626 GO:0042803 GO:0042825 GO:0043231 GO:0043531 GO:0046968 GO:0046978 GO:0046979 GO:0046980 GO:0046982 GO:0055085
110.440.8831.890.180.973vx4D GO:0000166 GO:0005524 GO:0006508 GO:0006810 GO:0008233 GO:0008234 GO:0016020 GO:0016021 GO:0016887 GO:0022885 GO:0042626 GO:0043213 GO:0055085
120.440.8881.920.220.984mrrA GO:0000166 GO:0005524 GO:0005886 GO:0006810 GO:0006811 GO:0016020 GO:0016021 GO:0016887 GO:0042626 GO:0046689 GO:0055085
130.430.8812.050.200.981jj7A GO:0000166 GO:0002250 GO:0002376 GO:0002474 GO:0002481 GO:0002485 GO:0002489 GO:0002591 GO:0005524 GO:0005739 GO:0005783 GO:0005789 GO:0006810 GO:0006952 GO:0015031 GO:0015197 GO:0015440 GO:0015833 GO:0016020 GO:0016021 GO:0016032 GO:0016887 GO:0019060 GO:0019885 GO:0023029 GO:0030176 GO:0042270 GO:0042287 GO:0042288 GO:0042605 GO:0042626 GO:0042803 GO:0042825 GO:0043231 GO:0043531 GO:0043657 GO:0046967 GO:0046978 GO:0046979 GO:0046980 GO:0046982 GO:0055085
140.420.8722.200.240.983nhaA GO:0000139 GO:0000166 GO:0005524 GO:0005739 GO:0005740 GO:0005741 GO:0005743 GO:0005768 GO:0005783 GO:0005789 GO:0005794 GO:0005886 GO:0006779 GO:0006810 GO:0006879 GO:0007420 GO:0010008 GO:0015232 GO:0015439 GO:0015562 GO:0015886 GO:0016020 GO:0016021 GO:0016887 GO:0020037 GO:0031307 GO:0042626 GO:0043190 GO:0043588 GO:0055085 GO:0070062
150.410.8612.270.200.973b5jA GO:0000166 GO:0005524 GO:0005886 GO:0006508 GO:0006810 GO:0008233 GO:0008565 GO:0016020 GO:0016021 GO:0016787 GO:0016887 GO:0030253 GO:0030256 GO:0042626 GO:0055085
160.410.8192.440.180.952onkA GO:0000166 GO:0005524 GO:0005886 GO:0006810 GO:0015412 GO:0015689 GO:0016020 GO:0016787 GO:0016887
170.410.8092.210.170.914c3zA GO:0000166 GO:0005215 GO:0005524 GO:0005886 GO:0005887 GO:0006691 GO:0006810 GO:0009235 GO:0015420 GO:0015889 GO:0016020 GO:0016021 GO:0016323 GO:0016787 GO:0016887 GO:0035461 GO:0042493 GO:0042626 GO:0043225 GO:0055085 GO:0070062 GO:0098656
180.410.8792.150.220.983wmgA GO:0000166 GO:0005524 GO:0006810 GO:0016020 GO:0016021 GO:0016887 GO:0042626 GO:0055085
190.410.8132.730.130.961g6hA GO:0000166 GO:0005524 GO:0006810 GO:0006865 GO:0016887
200.400.7152.390.200.822awnC GO:0000166 GO:0005215 GO:0005524 GO:0005886 GO:0006810 GO:0008643 GO:0015423 GO:0015609 GO:0015768 GO:0016020 GO:0016787 GO:0016820 GO:0016887 GO:0031234 GO:0033613 GO:0042956 GO:0043190 GO:0055085 GO:1990060
210.400.8432.490.150.981ji0A GO:0000166 GO:0005524 GO:0015658 GO:0015803 GO:0016887
220.390.7713.200.180.942d2fA GO:0000166 GO:0005524 GO:0006810 GO:0016887 GO:0046872
230.390.8112.630.170.962d62A GO:0000166 GO:0005215 GO:0005524 GO:0006810 GO:0016820 GO:0016887 GO:0043190 GO:0055085
240.380.8931.900.210.984q4aA GO:0000166 GO:0005524 GO:0006810 GO:0006869 GO:0016020 GO:0016021 GO:0016887 GO:0034040 GO:0042626 GO:0046872 GO:0055085
250.370.7232.550.200.842awnA GO:0000166 GO:0005215 GO:0005524 GO:0005886 GO:0006810 GO:0008643 GO:0015423 GO:0015609 GO:0015768 GO:0016020 GO:0016787 GO:0016820 GO:0016887 GO:0031234 GO:0033613 GO:0042956 GO:0043190 GO:0055085 GO:1990060
260.370.8122.660.160.953gfoA GO:0000166 GO:0005524 GO:0005886 GO:0006810 GO:0006824 GO:0016020 GO:0016787 GO:0016887 GO:0043190
270.370.8542.260.200.973c41J GO:0000166 GO:0003333 GO:0005524 GO:0015424 GO:0015426 GO:0016887
280.370.9111.660.170.984pl0B GO:0000166 GO:0005524 GO:0005886 GO:0006810 GO:0015031 GO:0016020 GO:0016021 GO:0016887 GO:0030153 GO:0042626 GO:0043213 GO:0055085
290.360.8442.450.200.974huqB GO:0000166 GO:0005524 GO:0005886 GO:0006810 GO:0016020 GO:0016787 GO:0016887 GO:0043190
300.360.8812.070.200.983qf4B GO:0000166 GO:0005524 GO:0005886 GO:0006810 GO:0016020 GO:0016021 GO:0016887 GO:0042626 GO:0055085
310.360.8412.360.220.952yz2A GO:0000166 GO:0005524 GO:0005886 GO:0006810 GO:0016020 GO:0016787 GO:0016887 GO:0032217 GO:0032218
320.350.8642.180.180.974ry2A GO:0005524 GO:0006508 GO:0006810 GO:0008233 GO:0008234 GO:0016020 GO:0016021 GO:0016887 GO:0022885 GO:0042626 GO:0043213 GO:0055085
330.350.7742.510.180.902pzgA GO:0000166 GO:0005224 GO:0005254 GO:0005260 GO:0005524 GO:0005737 GO:0005765 GO:0005768 GO:0005769 GO:0005829 GO:0005886 GO:0006695 GO:0006810 GO:0006811 GO:0006821 GO:0006904 GO:0007585 GO:0009986 GO:0015106 GO:0015108 GO:0015701 GO:0016020 GO:0016021 GO:0016323 GO:0016324 GO:0016787 GO:0016887 GO:0017081 GO:0019869 GO:0019899 GO:0030165 GO:0030301 GO:0030660 GO:0031205 GO:0031901 GO:0034707 GO:0035774 GO:0042626 GO:0043225 GO:0043234 GO:0045921 GO:0048240 GO:0051454 GO:0055037 GO:0055085 GO:0060081 GO:0070062 GO:0071320 GO:1902161 GO:1902476 GO:1902943
340.350.8841.970.210.984m1mA GO:0000086 GO:0000166 GO:0002481 GO:0002485 GO:0002489 GO:0002591 GO:0005524 GO:0005886 GO:0006810 GO:0006855 GO:0008559 GO:0009986 GO:0015893 GO:0016020 GO:0016021 GO:0016787 GO:0016887 GO:0042623 GO:0042626 GO:0042908 GO:0046581 GO:0055085 GO:0070062 GO:0072089
350.350.8911.990.230.994mycA GO:0000166 GO:0005524 GO:0005739 GO:0005743 GO:0006810 GO:0006811 GO:0006879 GO:0016020 GO:0016021 GO:0016887 GO:0022857 GO:0042626 GO:0044281 GO:0055072 GO:0055085
360.350.8482.410.210.964huqA GO:0000166 GO:0005524 GO:0005886 GO:0006810 GO:0016020 GO:0016787 GO:0016887 GO:0043190
370.340.8522.470.240.975jszB GO:0000166 GO:0005524 GO:0005886 GO:0006810 GO:0016020 GO:0016787 GO:0016887 GO:0043190
380.340.8592.370.190.975d3mA GO:0000166 GO:0005524 GO:0005886 GO:0006810 GO:0016020 GO:0016787 GO:0016887 GO:0043190
390.340.8632.390.210.984u02A GO:0000166 GO:0003333 GO:0005524 GO:0015424 GO:0016887
400.340.8462.710.190.984mkiA GO:0000166 GO:0005524 GO:0005886 GO:0006810 GO:0016020 GO:0016787 GO:0016887 GO:0043190
410.340.8262.660.170.974hziA GO:0000166 GO:0005524 GO:0016887
420.340.7872.330.250.905dgxA GO:0000166 GO:0005319 GO:0005524 GO:0005886 GO:0006810 GO:0006869 GO:0016020 GO:0016021 GO:0016787 GO:0016887 GO:0034040 GO:0042626 GO:0043190 GO:0055085
430.330.7563.260.140.973gd7A GO:0000166 GO:0005215 GO:0005224 GO:0005254 GO:0005260 GO:0005524 GO:0005737 GO:0005765 GO:0005768 GO:0005769 GO:0005829 GO:0005886 GO:0006695 GO:0006810 GO:0006811 GO:0006821 GO:0006904 GO:0007585 GO:0008643 GO:0009986 GO:0015106 GO:0015108 GO:0015423 GO:0015609 GO:0015701 GO:0015768 GO:0016020 GO:0016021 GO:0016323 GO:0016324 GO:0016787 GO:0016820 GO:0016887 GO:0017081 GO:0019869 GO:0019899 GO:0030165 GO:0030301 GO:0030660 GO:0031205 GO:0031234 GO:0031901 GO:0033613 GO:0034707 GO:0035774 GO:0042626 GO:0042956 GO:0043190 GO:0043225 GO:0043234 GO:0045921 GO:0048240 GO:0051454 GO:0055037 GO:0055085 GO:0060081 GO:0070062 GO:0071320 GO:1902161 GO:1902476 GO:1902943 GO:1990060
440.330.8632.120.200.965eumA GO:0000166 GO:0005319 GO:0005524 GO:0005886 GO:0006810 GO:0006869 GO:0016020 GO:0016021 GO:0016787 GO:0016887 GO:0034040 GO:0042626 GO:0043190 GO:0055085
450.330.8012.710.170.951v43A GO:0000166 GO:0005215 GO:0005524 GO:0006810 GO:0016820 GO:0016887 GO:0043190 GO:0055085
460.320.8402.300.150.954dblC GO:0000166 GO:0005524 GO:0005829 GO:0005886 GO:0006810 GO:0015420 GO:0015889 GO:0016020 GO:0016787 GO:0016887 GO:0019898 GO:0031234 GO:0035461 GO:0043190
470.320.8582.110.200.964ymsA GO:0000166 GO:0003333 GO:0005524 GO:0015424 GO:0016887
480.320.6372.140.200.722awnD GO:0000166 GO:0005215 GO:0005524 GO:0005886 GO:0006810 GO:0008643 GO:0015423 GO:0015609 GO:0015768 GO:0016020 GO:0016787 GO:0016820 GO:0016887 GO:0031234 GO:0033613 GO:0042956 GO:0043190 GO:0055085 GO:1990060
490.310.7952.300.200.901f3oA GO:0000166 GO:0005524 GO:0006810 GO:0016887
500.300.8512.280.130.964p33A GO:0000166 GO:0005524 GO:0005737 GO:0005886 GO:0006810 GO:0015437 GO:0015920 GO:0016020 GO:0016787 GO:0016887 GO:0032403 GO:0043190 GO:0055085
510.300.8232.740.170.964rvcA GO:0000166 GO:0005524 GO:0016887
520.290.8042.920.220.971z47A GO:0000166 GO:0005215 GO:0005524 GO:0006810 GO:0016820 GO:0016887 GO:0043190 GO:0055085
530.280.8422.440.180.964yerA GO:0000166 GO:0005524 GO:0016887 GO:0043215 GO:1900753
540.280.8492.570.190.984g1uC GO:0000166 GO:0005524 GO:0005886 GO:0006810 GO:0015439 GO:0015886 GO:0016020 GO:0016787 GO:0016887 GO:0043190
550.270.8472.150.230.944ayxA GO:0000166 GO:0005215 GO:0005524 GO:0005739 GO:0005743 GO:0006810 GO:0016020 GO:0016021 GO:0016887 GO:0032592 GO:0042626 GO:0042803 GO:0055085
560.260.8522.460.180.982ihyB GO:0005524 GO:0016887
570.260.8582.200.240.973tuzC GO:0000166 GO:0003333 GO:0005524 GO:0005886 GO:0006810 GO:0006865 GO:0009276 GO:0015424 GO:0015821 GO:0016020 GO:0016787 GO:0016887 GO:0042626 GO:0043190 GO:0048473 GO:0048474 GO:0055085
580.250.7543.090.180.922pjzA GO:0005524 GO:0016887
590.250.7933.090.140.984wbsB GO:0000166 GO:0005524 GO:0016887 GO:0043190 GO:0055085
600.230.7872.410.210.902pcjA GO:0000166 GO:0005524 GO:0005886 GO:0006810 GO:0016020 GO:0016787 GO:0016887 GO:0042953 GO:0042954 GO:0043190
610.220.6212.800.160.744q7kA GO:0000166 GO:0005524 GO:0006810 GO:0006869 GO:0016020 GO:0016021 GO:0016887 GO:0034040 GO:0042626 GO:0046872 GO:0055085
620.220.8911.910.190.984f4cA GO:0000166 GO:0005524 GO:0006810 GO:0006855 GO:0008559 GO:0010038 GO:0015562 GO:0016020 GO:0016021 GO:0016324 GO:0016787 GO:0016887 GO:0042626 GO:0042908 GO:0045087 GO:0050829 GO:0055085 GO:0093002
630.210.8522.480.170.984fwiB GO:0000166 GO:0005524 GO:0006810 GO:0015833 GO:0016887 GO:0046872 GO:0051536 GO:0051539
640.200.8532.280.180.974tquS GO:0000166 GO:0005524 GO:0005886 GO:0006810 GO:0016020 GO:0016887
650.180.8242.460.200.962yyzA GO:0000166 GO:0005215 GO:0005524 GO:0006810 GO:0016820 GO:0016887 GO:0043190 GO:0055085
660.160.8312.650.140.961vplA GO:0005524 GO:0016887
670.160.8222.690.190.972it1A GO:0000166 GO:0005524 GO:0016887
680.160.8282.600.190.962zu0C GO:0000166 GO:0005524 GO:0005737 GO:0005829 GO:0006810 GO:0016226 GO:0016887
690.140.7752.430.170.905c73A GO:0000166 GO:0005524 GO:0006810 GO:0016021 GO:0016887 GO:0042626 GO:0055085
700.140.7252.530.180.841sgwA GO:0005524 GO:0016887
710.130.6813.180.140.843qf7A GO:0000166 GO:0005524 GO:0006281 GO:0006974 GO:0016787 GO:0046872
720.120.7682.760.190.912nq2C GO:0000166 GO:0005524 GO:0006810 GO:0016887
730.090.8182.590.170.953d31A GO:0000166 GO:0005524 GO:0016887
740.070.7633.330.190.961g291 GO:0000166 GO:0005215 GO:0005524 GO:0005886 GO:0006810 GO:0008643 GO:0015423 GO:0015768 GO:0016020 GO:0016787 GO:0016820 GO:0016887 GO:0043190 GO:0046872 GO:0055085
750.070.8042.790.220.983b5xA GO:0000166 GO:0005319 GO:0005524 GO:0005886 GO:0006810 GO:0006869 GO:0016020 GO:0016021 GO:0016787 GO:0016887 GO:0034040 GO:0042626 GO:0043190 GO:0055085


Consensus prediction of GO terms
 
Molecular Function GO:0005524 GO:0030165 GO:0015106 GO:0005260 GO:0019869 GO:0019899 GO:0005224 GO:0043225 GO:0008144 GO:0008289 GO:0034040 GO:0015437 GO:0015408
GO-Score 0.97 0.78 0.78 0.78 0.78 0.78 0.54 0.54 0.49 0.49 0.49 0.49 0.48
Biological Processes GO:0071320 GO:0060081 GO:0006904 GO:0051454 GO:0048240 GO:1902476 GO:0045921 GO:0030301 GO:1902943 GO:0015701 GO:0035774 GO:0006695 GO:1902161 GO:0007585 GO:0003254 GO:1901264 GO:0015682 GO:0055072
GO-Score 0.78 0.78 0.78 0.78 0.78 0.78 0.78 0.78 0.78 0.78 0.78 0.78 0.78 0.54 0.51 0.49 0.48 0.48
Cellular Component GO:0005829 GO:0031205 GO:0031901 GO:0055037 GO:0009986 GO:0034707 GO:0070062 GO:0016324 GO:0043190 GO:0030660 GO:0016323 GO:0005765
GO-Score 0.78 0.78 0.78 0.78 0.78 0.78 0.78 0.78 0.73 0.54 0.54 0.54

(a)CscoreGO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)TM-score is a measure of global structural similarity between query and template protein.
(c)RMSDa is the RMSD between residues that are structurally aligned by TM-align.
(d)IDENa is the percentage sequence identity in the structurally aligned region.
(e)Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on CscoreGO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]



Please cite the following articles when you use the I-TASSER server:
1. J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2. J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.