Threading Zmax Znorm MUSTER 8.36 1.44 dPPAS 6.63 0.71 wdPPAS 7.33 0.79 wMUSTER 4.74 0.82 wPPAS 7.61 1.09 dPPAS2 11.63 1.11 PPAS 6.51 0.93 Env-PPAS 8.16 1.02 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=15546) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -0.66 0.63+-0.14 4.9+-3.2 12730 0.525 model2 -1.83 2313 0.162 model3 -3.51 702 0.030 model4 -0.60 11836 0.556 model5 -5.00 46 0.002 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).