I-TASSER results

I-TASSER results for job id Rv2926c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (207 residues)
MDLGGVRRRISLMARQHGPTAQRHVASPMTVDIARLGRRPGAMFELHDTVHSPARIGLEL
IAIDQGALLDLDLRVESVSEGVLVTGTVAAPTVGECARCLSPVRGRVQVALTELFAYPDS
ATDETTEEDEVGRVVDETIDLEQPIIDAVGLELPFSPVCRPDCPGLCPQCGVPLASEPGH
RHEQIDPRWAKLVEMLGPESDTLRGER

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 \| \| \| \| \| \| \| \| \| \| MDLGGVRRRISLMARQHGPTAQRHVASPMTVDIARLGRRPGAMFELHDTVHSPARIGLELIAIDQGALLDLDLRVESVSEGVLVTGTVAAPTVGECARCLSPVRGRVQVALTELFAYPDSATDETTEEDEVGRVVDETIDLEQPIIDAVGLELPFSPVCRPDCPGLCPQCGVPLASEPGHRHEQIDPRWAKLVEMLGPESDTLRGER
Prediction	CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHCCCCEEEEEEEHCCHHHHCCCCCCCCCCCCEEEEEEEEEHCCEEEEEEEEEEEEEEEHCCCCCCEEEEEEEEEEEEEHCCCCCCCCCCCCCCEEEHCCCEHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
Conf.Score	987776666555556778877778889836777788768995699999976757757654556788658999999997989999999999999985788997678999999999986887777888777657877985579999999999989986579987789888889987668876678899769999987766566655679
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 \| \| \| \| \| \| \| \| \| \| MDLGGVRRRISLMARQHGPTAQRHVASPMTVDIARLGRRPGAMFELHDTVHSPARIGLELIAIDQGALLDLDLRVESVSEGVLVTGTVAAPTVGECARCLSPVRGRVQVALTELFAYPDSATDETTEEDEVGRVVDETIDLEQPIIDAVGLELPFSPVCRPDCPGLCPQCGVPLASEPGHRHEQIDPRWAKLVEMLGPESDTLRGER
Prediction	673543344143125454445445472202010440374674515054416225514452350665440404030344542020303040403033112044162515040321023446645544442211204533020231022100010213101477053204614441565666676632326433560176667777778
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHCCCCEEEEEEEHCCHHHHCCCCCCCCCCCCEEEEEEEEEHCCEEEEEEEEEEEEEEEHCCCCCCEEEEEEEEEEEEEHCCCCCCCCCCCCCCEEEHCCCEHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
MDLGGVRRRISLMARQHGPTAQRHVASPMTVDIARLGRRPGAMFELHDTVHSPARIGLELIAIDQGALLDLDLRVESVSEGVLVTGTVAAPTVGECARCLSPVRGRVQVALTELFAYPDSATDETTEEDEVGRVVDETIDLEQPIIDAVGLELPFSPVCRPDCPGLCPQCGVPLASEPGHRHEQIDPRWAKLVEMLGPESDTLRGER

4csqA

0.14

0.08

0.55

1.09

dPPAS

---------GSHMTTQRYLLDELETADMLEID-----GLHAWRFELNENLLDQADLAAEADQPFASEDWVLAVESLDGRTRREWRFSYNAVMEAEPQADGESWRLTTGEGAYQLRCLGAVSASGEDE--------------------------------------------------------------------------------

2mvoA

0.15

0.10

0.66

1.08

wdPPAS

HHSSGLVPRGSGMKETAAKFERQHMDSP------DLGTDDDDK----TGGGRADPAHRSPVPLPSPTSNKQDISEANLAYLWPLTVD---HGTIEC----PSDNAVFVAPDGTTYALNDRAEKAGHPPITPIRAKGGYISLGALLSTTLNLC-----------KG------------------------------------------

2m9hA

0.19

0.02

0.13

1.19

dPPAS2

IQQQGYRGKNSVAARSPEKASNMENNE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

2ygdA

0.10

0.07

0.71

1.06

dPPAS

FGEHLLESDLFPTSTSLSPFYLRPPS------FLRAPSWFDTGLSEMRLEKDRFSVNLDVKHFSPEEL-----KVKVLGDVIEVHGKHEERQDE---------HGFISREFHRKYRIPADVD---PLTITSSLSSDGVL----------TVNGPRKQVSGPERTIPITREEKPAVTAAPKK--------------------------

2kk9A

0.13

0.01

0.11

1.13

dPPAS2

ASRKGLRRDLDASREAKKQVEKA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

2mvoA

0.10

0.07

0.68

1.00

dPPAS

HHSSGLVPRGSGMKETAAAKFERQHMDS---------PDLGTDDDDKTGGGRADPAHRSPVPLPSPTSNKQDISEANLAYLWPLTVDHGTIECLP-----SDNAVFVAPDGTTYALNDRAEKAGHPPITPIRAKGGGYISLGALLSTTLNLCGKG----------------------------------------------------

5l5gA

0.11

0.10

0.92

0.72

MUSTER

CKYRNLCTHDPTTCSFQEGRINVSEDCPQLVPTEEILIPVGEVKPITLKA--------RNLPQPQSGQRGYECVLSIQGAVHRVPALRFNSSSVQCQNSSYQYDGMSNLAVDFAVVWNGNFIIDNPQDLKVHLYKCAAQR-----SCGLCLKADHKFECERRCHQHCPSTSSPWLDWSSHNVKCSNPQ---ITEILTVSGPPEGGTR

5dz8A

0.10

0.07

0.70

0.99

dPPAS

VAFDIKAQAKGVAEYGNSITAKTKPDGSFEFNHDIDGVKTIGYGKLTGKVNHHYVANKDGVAQNAAVNQNIVFRVLTKDGRPIFEKAHNG---------NKTFAETLNKTLQLNLKYELKPHASSGNVEVFKIHDDWVHD----------------------THGSALVSYVNNN--------------------------------

2ygdA

0.10

0.07

0.67

0.92

wdPPAS

FDQ-GEHLLESDLFPTSTSLSPFYLRPP----LRAPSWFRLEKDRFSVNLDVK---HFSPEELK----------VKVLGDVIEVHGKHEERQD----------HGFISREFHRKYRIPADVD---PLTITSSLSSDGVL----------TVNGPRKQVSGPE---TIPITREEKPAVTAAPKK------------------------

4oj5A2

0.16

0.14

0.90

0.70

wMUSTER

GSLIGIHPQGTLVLTVRTPEQYNAVGDGIADDTSKLKEMLSDINNVPETLPDAAAVNSYMEQVA----VKIDLTLYRFTETLYIPPGVSIEITRECKQGLDPVDKNTAAISLMVYRKQPDGSKDVDDNGDAITCARK-IDINNL-----LITAPVKVIGGAGCKGLS--IGE--NTGSDITTARL-PR-----GLLQSASWGSENLR

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-4.13

Estimated TM-score = 0.28±0.09

Estimated RMSD = 15.5±3.4Å

Download Model 2

C-score=-4.31

Download Model 3

C-score=-4.04

Download Model 4

C-score=-3.72

Download Model 5

C-score=-4.76

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	2mvoA	0.479	3.31	0.103	0.599
2	4ui9A2	0.461	5.60	0.060	0.807
3	1e6yA	0.458	5.58	0.056	0.778
4	4h1gA	0.457	5.67	0.040	0.797
5	1e6vA	0.453	5.64	0.051	0.778
6	4cr2Z	0.452	5.17	0.070	0.734
7	3sqgA	0.449	5.68	0.051	0.778
8	1n7qA	0.447	5.80	0.055	0.797
9	2veoA	0.445	5.78	0.051	0.792
10	1sb3D	0.445	5.64	0.047	0.773

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.11	6	3wmnA	MQ8	Rep, Mult	149,153
2	0.07	4	3sqgD	M43	Rep, Mult	77,78,140,143,160
3	0.07	4	3gwzD	CA	Rep, Mult	143,147
4	0.06	3	3gtgA	ZN	Rep, Mult	96,99,159,170
5	0.04	2	5d91A	8K6	Rep, Mult	138,141
6	0.04	2	1ocoB	HEA	Rep, Mult	145,146
7	0.04	2	4lqhA	MG	Rep, Mult	142,143
8	0.02	1	3b08B	ZN	Rep, Mult	159,163,167,170
9	0.02	1	2xjmH	CO	Rep, Mult	183,186
10	0.02	1	1focA	HEM	Rep, Mult	159,163
11	0.02	1	1hbmA	NA	Rep, Mult	168,170,171,172,173

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	2e1qA	0.404	6.17	0.049	0.744	1.17.3.2,1.17.1.4	NA
2	0.060	1djnA	0.420	5.75	0.103	0.734	1.5.8.2,1.5.99.7	NA
3	0.060	5acnA	0.428	5.98	0.026	0.778	4.2.1.3	NA
4	0.060	2pdaA	0.422	5.74	0.027	0.734	1.2.7.1	121
5	0.060	1yscA	0.428	5.39	0.063	0.725	3.4.16.5	NA
6	0.060	2v4wD	0.330	6.27	0.070	0.623	2.3.3.10	84,154
7	0.060	2pahA	0.324	6.77	0.034	0.671	1.14.16.1	NA
8	0.060	2tmdA	0.419	5.89	0.074	0.754	1.5.8.2	NA
9	0.060	1c7sA	0.363	6.32	0.045	0.715	3.2.1.52	NA
10	0.060	2j5wA	0.426	5.75	0.067	0.730	1.16.3.1	NA
11	0.060	1e6yA	0.458	5.58	0.056	0.778	2.8.4.1	152
12	0.060	1asqA	0.432	5.47	0.048	0.734	1.10.3.3	92
13	0.060	2e52A	0.428	5.56	0.045	0.730	3.1.21.4	142
14	0.060	2p4qA	0.424	5.98	0.042	0.778	1.1.1.44	152
15	0.060	2gtqA	0.421	4.73	0.050	0.652	3.4.11.2	NA
16	0.060	1j0mA	0.357	5.94	0.038	0.642	4.2.2.12	193
17	0.060	2vn7A	0.435	6.08	0.069	0.807	3.2.1.3	NA
18	0.060	1ayxA	0.425	5.81	0.074	0.763	3.2.1.3	NA
19	0.060	1ug9A	0.419	5.81	0.048	0.749	3.2.1.70	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.07	0.457	5.67	0.04	0.80	4h1gA	GO:0000166 GO:0003777 GO:0005215 GO:0005363 GO:0005524 GO:0005874 GO:0006810 GO:0007018 GO:0008017 GO:0015768
1	0.07	0.453	5.64	0.05	0.78	1e6vA	GO:0015948 GO:0016740 GO:0046872 GO:0050524
2	0.07	0.457	5.59	0.05	0.78	1e6yA	GO:0015948 GO:0016740 GO:0046872 GO:0050524
3	0.07	0.453	5.76	0.07	0.78	1hbmA	GO:0015948 GO:0016740 GO:0046872 GO:0050524
4	0.06	0.414	5.58	0.06	0.71	4qvhA	GO:0000287 GO:0005215 GO:0005363 GO:0005886 GO:0006810 GO:0006974 GO:0008643 GO:0008897 GO:0009239 GO:0009366 GO:0015768 GO:0016740 GO:0016780 GO:0019540 GO:0030288 GO:0034289 GO:0042597 GO:0042956 GO:0043190 GO:0055052 GO:0060326 GO:1901982 GO:1990060
5	0.06	0.393	5.75	0.06	0.69	4nufA	GO:0000122 GO:0003677 GO:0003707 GO:0003714 GO:0005215 GO:0005363 GO:0005634 GO:0005737 GO:0006351 GO:0006355 GO:0006810 GO:0007219 GO:0008134 GO:0009749 GO:0010628 GO:0010629 GO:0015768 GO:0019904 GO:0031100 GO:0032024 GO:0032403 GO:0042803 GO:0042974 GO:0042975 GO:0043234 GO:0043401 GO:0043433 GO:0045892 GO:0046965 GO:0046966
6	0.06	0.434	5.26	0.05	0.73	3py7A	GO:0001725 GO:0003677 GO:0005178 GO:0005215 GO:0005363 GO:0005654 GO:0005737 GO:0005829 GO:0005856 GO:0005875 GO:0005886 GO:0005925 GO:0005938 GO:0006351 GO:0006355 GO:0006810 GO:0006936 GO:0006974 GO:0007155 GO:0007160 GO:0007165 GO:0007172 GO:0007173 GO:0007179 GO:0008013 GO:0008270 GO:0008643 GO:0015768 GO:0016032 GO:0017166 GO:0019901 GO:0030027 GO:0030054 GO:0030288 GO:0032403 GO:0034289 GO:0034614 GO:0042025 GO:0042597 GO:0042956 GO:0043190 GO:0044204 GO:0046872 GO:0048010 GO:0055052 GO:0060326 GO:0060396 GO:1901982 GO:1990060
7	0.06	0.323	5.97	0.05	0.57	4aouA	GO:0000166 GO:0000287 GO:0004450 GO:0006099 GO:0006102 GO:0016491 GO:0016616 GO:0046872 GO:0051287 GO:0055114
8	0.06	0.349	6.20	0.06	0.66	4blbB	GO:0000122 GO:0001501 GO:0001843 GO:0001947 GO:0003281 GO:0003714 GO:0004871 GO:0005215 GO:0005363 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0005929 GO:0006355 GO:0006508 GO:0006810 GO:0006974 GO:0007165 GO:0007275 GO:0007368 GO:0008013 GO:0008134 GO:0008643 GO:0015768 GO:0019901 GO:0021513 GO:0021775 GO:0021776 GO:0030288 GO:0034289 GO:0035904 GO:0042597 GO:0042956 GO:0042992 GO:0042994 GO:0043190 GO:0043433 GO:0043588 GO:0045668 GO:0045879 GO:0055052 GO:0060326 GO:0060976 GO:0072372 GO:0097542 GO:0097546 GO:1901621 GO:1901982 GO:1990060 GO:2000059
9	0.06	0.323	5.97	0.04	0.59	1v8jA	GO:0000166 GO:0000775 GO:0000776 GO:0000777 GO:0003777 GO:0005524 GO:0005634 GO:0005694 GO:0005737 GO:0005856 GO:0005871 GO:0005874 GO:0005881 GO:0007018 GO:0007019 GO:0007049 GO:0007059 GO:0007067 GO:0007080 GO:0008017 GO:0015630 GO:0016020 GO:0016887 GO:0030951 GO:0035371 GO:0051010 GO:0051301 GO:0051983
10	0.06	0.359	5.55	0.04	0.63	4ifpA	GO:0000166 GO:0002376 GO:0005215 GO:0005363 GO:0005524 GO:0005622 GO:0005634 GO:0005737 GO:0005829 GO:0006810 GO:0006915 GO:0006919 GO:0006954 GO:0006974 GO:0008643 GO:0008656 GO:0015768 GO:0019899 GO:0019904 GO:0030288 GO:0032495 GO:0034289 GO:0042597 GO:0042742 GO:0042956 GO:0042981 GO:0043190 GO:0045087 GO:0050718 GO:0050727 GO:0051402 GO:0055052 GO:0060326 GO:0061702 GO:0072558 GO:1901982 GO:1990060
11	0.06	0.317	6.23	0.07	0.60	2h58A	GO:0000166 GO:0003777 GO:0005524 GO:0005737 GO:0005794 GO:0005813 GO:0005815 GO:0005856 GO:0005871 GO:0005874 GO:0005912 GO:0005915 GO:0007017 GO:0007018 GO:0007030 GO:0007601 GO:0008017 GO:0008569 GO:0016020 GO:0016887 GO:0030054 GO:0030659 GO:0031410 GO:0045218 GO:0070062 GO:0090136
12	0.06	0.388	5.64	0.06	0.67	1y4cA	GO:0005215 GO:0005363 GO:0006810 GO:0006974 GO:0008643 GO:0015768 GO:0030288 GO:0034289 GO:0042597 GO:0042956 GO:0043190 GO:0055052 GO:0060326 GO:1901982 GO:1990060
13	0.06	0.358	5.90	0.03	0.64	1a0dA	GO:0000287 GO:0005737 GO:0005975 GO:0006098 GO:0009045 GO:0016853 GO:0042732 GO:0046872
14	0.06	0.367	6.05	0.03	0.69	4w7sA	GO:0000166 GO:0000384 GO:0000395 GO:0003676 GO:0003723 GO:0004004 GO:0004386 GO:0005524 GO:0005634 GO:0005682 GO:0005737 GO:0006397 GO:0006413 GO:0007059 GO:0008380 GO:0010468 GO:0010501 GO:0016787 GO:0036464
15	0.06	0.339	6.23	0.03	0.65	4aoyA	GO:0000287 GO:0004450 GO:0006099 GO:0006102 GO:0016491 GO:0016616 GO:0046872 GO:0051287 GO:0055114
16	0.06	0.299	6.18	0.03	0.58	4hs7A	GO:0005363 GO:0015768
17	0.06	0.362	6.07	0.03	0.66	5azaA	GO:0004576 GO:0005215 GO:0005363 GO:0006486 GO:0006810 GO:0006974 GO:0008643 GO:0015768 GO:0016020 GO:0016021 GO:0016740 GO:0030288 GO:0034289 GO:0042597 GO:0042956 GO:0043190 GO:0055052 GO:0060326 GO:1901982 GO:1990060
18	0.06	0.344	5.78	0.08	0.60	4c57A	GO:0000166 GO:0004672 GO:0004674 GO:0005524 GO:0005737 GO:0005794 GO:0005829 GO:0005925 GO:0006468 GO:0006898 GO:0007029 GO:0007030 GO:0007049 GO:0010977 GO:0016020 GO:0016301 GO:0016310 GO:0016740 GO:0030054 GO:0030332 GO:0031982 GO:0043231 GO:0048471 GO:0072318 GO:0072583 GO:0072600 GO:0090002 GO:0090160

Consensus prediction of GO terms

Molecular Function	GO:0050497	GO:0043169
GO-Score	0.37	0.37
Biological Processes	GO:0009061	GO:0015975	GO:0015947	GO:0043447
GO-Score	0.37	0.37	0.37	0.37
Cellular Component	GO:0055052	GO:0030288	GO:0005874	GO:0009366	GO:1990060
GO-Score	0.07	0.07	0.07	0.07	0.07

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.