I-TASSER results

I-TASSER results for job id Rv2884

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (252 residues)
MPTGPTTGKWHPHEVWRYLLEVLLLTDEADLESALPELESFAQSVQRAPLDDPGAAKGAD
ADVAIIDARADLAAARRVCRRLTTSAPALAVVAVVAPANFVAVDGDWIFDDVLLNAAGGA
ELQARLRLAITRRRSTLAGTLQFGDLVLHPASYTASLGDRDLGLTLTEFKLMNFLVQHAG
RAFTRTRLMREVWGYECHGRIRTVDVHVRRLRAKLGAEHESMIDTVRGVGYMAVTPPQPR
WIISESILNRCK

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 \| \| \| \| \| \| \| \| \| \| \| \| MPTGPTTGKWHPHEVWRYLLEVLLLTDEADLESALPELESFAQSVQRAPLDDPGAAKGADADVAIIDARADLAAARRVCRRLTTSAPALAVVAVVAPANFVAVDGDWIFDDVLLNAAGGAELQARLRLAITRRRSTLAGTLQFGDLVLHPASYTASLGDRDLGLTLTEFKLMNFLVQHAGRAFTRTRLMREVWGYECHGRIRTVDVHVRRLRAKLGAEHESMIDTVRGVGYMAVTPPQPRWIISESILNRCK
Prediction	CCCCCCCCCCCCCCCCCCCEEEEEHCCCHHHHHHHHHHHCCCEEEHCCHHHHHHHHHHCCCCEEEEHCCCCCCCHHHHHHHHHHCCCCEEEEEHCCCCCEEEHCCCCCCCCEHCCCCCHHHHHHHHHHHHHCCCCCCCCEEEHCCEEEHCCEEEEEHCCEEHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHCCCCCCEEEEHCCCEEEHCCCCCCCCCCCCCCCCCCC
Conf.Score	999998877788888888758999879878999999985986899868899999999799989999678999988999999997599868998567776566466678874656899999999999999857899888859998999967858999999997698789999999998689768999999997698767766444677899999979999865887578578975888777765556445579
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 \| \| \| \| \| \| \| \| \| \| \| \| MPTGPTTGKWHPHEVWRYLLEVLLLTDEADLESALPELESFAQSVQRAPLDDPGAAKGADADVAIIDARADLAAARRVCRRLTTSAPALAVVAVVAPANFVAVDGDWIFDDVLLNAAGGAELQARLRLAITRRRSTLAGTLQFGDLVLHPASYTASLGDRDLGLTLTEFKLMNFLVQHAGRAFTRTRLMREVWGYECHGRIRTVDVHVRRLRAKLGAEHESMIDTVRGVGYMAVTPPQPRWIISESILNRCK
Prediction	855645544444664442011000031264015005624624131141165014305745000000102036330240032027634100000214554313000313040100122235001010201011355657430412503023631303167551702330030032005247201125301640452414433210001032015114776452010111020204337575544555435618
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCCCCCCCCCCCCEEEEEHCCCHHHHHHHHHHHCCCEEEHCCHHHHHHHHHHCCCCEEEEHCCCCCCCHHHHHHHHHHCCCCEEEEEHCCCCCEEEHCCCCCCCCEHCCCCCHHHHHHHHHHHHHCCCCCCCCEEEHCCEEEHCCEEEEEHCCEEHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHCCCCCCEEEEHCCCEEEHCCCCCCCCCCCCCCCCCCC
MPTGPTTGKWHPHEVWRYLLEVLLLTDEADLESALPELESFAQSVQRAPLDDPGAAKGADADVAIIDARADLAAARRVCRRLTTSAPALAVVAVVAPANFVAVDGDWIFDDVLLNAAGGAELQARLRLAITRRRSTLAGTLQFGDLVLHPASYTASLGDRDLGLTLTEFKLMNFLVQHAGRAFTRTRLMREVWGYECHGRIRTVDVHVRRLRAKLGAEHESMIDTVRGVGYMAVTPPQPRWIISESILNRCK

4kfcA

0.25

0.21

0.86

3.79

MUSTER

-----------------AMANVLIVEDEQAIRRFLRTALEMRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDGIEFIRDLRQAVPVIVLSARSEESDKIA-ALDAGADDYLSKPFGIGELQARLRVALRRHSAPDP-LVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLLAVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDRPRHFITATGIGYRFML-----------------

4kfcA

0.24

0.21

0.86

4.53

dPPAS

-----------------AMANVLIVEDEQAIRRFLRTALEMRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDGIEFIRDLRQAVPVIVLSARSEESDKI-AALDAGADDYLSKPFGIGELQARLRVALRRHSAPDP-LVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLLAVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPPRHFITATGIGYRFML-----------------

4kfcA

0.24

0.21

0.86

4.27

wdPPAS

-----------------AMANVLIVEDERRFLRTALEGDGMRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDGIEFIRDLRQAVPVIVLSARSEESDKI-AALDAGADDYLSKPFGIGELQARLRVALRRHSAPDP-LVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLLAVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPPRHFITATGIGYRFML-----------------

4kfcA

0.24

0.21

0.85

4.08

wMUSTER

------------------MANVLIVEDEQAIRRFLRTAL-MRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDGIEFIRDLRQAVPVIVLSARSEESDKI-AALDAGADDYLSKPFGIGELQARLRVALRRHSAPDP-LVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLLAVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPPRHFITATGIGYRFML-----------------

4kfcA

0.24

0.21

0.85

3.84

wPPAS

-----------------AMANVLIVEDEQAIRRFLRTAL-MRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDGIEFIRDLRQAVPVIVLSARSEESDKI-AALDAGADDYLSKPFGIGELQARLRVALRRHSAP-DPLVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLLAVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPPRHFITATGIGYRFML-----------------

4kfcA

0.24

0.21

0.86

4.28

dPPAS2

-----------------AMANVLIVEDEQAIRRFLRTALEMRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDGIEFIRDLRQAVPVIVLSARSEESDKI-AALDAGADDYLSKPFGIGELQARLRVALRRHSAPDP-LVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLLAVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPPRHFITATGIGYRFML-----------------

4kfcA

0.24

0.21

0.85

3.79

PPAS

-----------------AMANVLIVEDEQAIRRFLRTAL-MRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDGIEFIRDLRQAVPVIVLSARSEESDKI-AALDAGADDYLSKPFGIGELQARLRVALRRHSAP-DPLVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLLAVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDRPRHFITATGIGYRFML-----------------

4kfcA

0.24

0.21

0.86

4.76

Env-PPAS

-----------------AMANVLIVEDEQAIRRFLRTALEMRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDGIEFIRDLRQAVPVIVLSARSEESDKI-AALDAGADDYLSKPFGIGELQARLRVALRRHSAPDP-LVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLLAVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPPRHFITATGIGYRFML-----------------

1ys6B

0.27

0.23

0.86

3.62

MUSTER

------------------SPRVLVVDDDSDVLASLERGLRFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVSVVTALRAMVPVCVLSARSSVDDRVA-GLEAGADDYLVKPFVLAELVARVKALLRRRGSSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGPRLLHTVRGVGFVLRMQ----------------

2oqrA

0.30

0.26

0.85

4.23

dPPAS

------------------ATSVLIVEDEADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRARVPVIMVTARDSEIDKV-VGLELGADDYVTKPYSARELIARIRAVLRRGSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPPVHLVTVRGLGYKLE------------------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-0.19

Estimated TM-score = 0.69±0.12

Estimated RMSD = 6.2±3.8Å

Download Model 2

C-score=-1.72

Download Model 3

C-score=-2.29

Download Model 4

C-score=-4.12

Download Model 5

C-score=-4.40

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	4kfcA	0.839	0.89	0.245	0.857
2	4a0fA	0.540	4.93	0.052	0.782
3	1eftA	0.515	4.70	0.097	0.718
4	3agjA	0.511	4.71	0.107	0.714
5	4s04A	0.510	4.65	0.199	0.706
6	1wb1C	0.508	4.51	0.076	0.679
7	3p26A	0.508	5.13	0.099	0.730
8	2vycA	0.505	4.33	0.083	0.659
9	5iw7A	0.503	5.07	0.086	0.746
10	4zkdA	0.502	4.54	0.055	0.694

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.42	61	1peyA	MN	Rep, Mult	27,67,69,115
2	0.19	31	1wb3C	DXC	Rep, Mult	68,69,75,91,93
3	0.10	16	1f4vA	III	Rep, Mult	95,97,98,101,105,109,110,111,112,113,114,125,128
4	0.02	4	1gxpA	NUC	Rep, Mult	166,167,168,193,198,199,200,203,206,207,210,227
5	0.01	2	3myyA	BEF	Rep, Mult	45,46,51,55
6	0.01	2	1ffwA	PON	Rep, Mult	27,28,29
7	0.01	2	1zdmA	XE	Rep, Mult	25,26,35,65,66,67,91
8	0.01	2	3p27A	GDP	Rep, Mult	26,27,28,31,32,33,34
9	0.01	3	3gwgA	MG	Rep, Mult	31,115
10	0.01	2	2z33A	NUC	Rep, Mult	185,202,205,209,212,225,227,228,231
11	0.01	2	3cw2B	III	Rep, Mult	94,96,100,102,105,112,113,114,117,118,120,121,129
12	0.00	1	1wb1A	UUU	Rep, Mult	93,115,116
13	0.00	1	2a9rA	MG	Rep, Mult	24,26,32,45,46,47
14	0.00	1	3olvA	BEF	Rep, Mult	47,51
15	0.00	1	2pmuB	GLY	Rep, Mult	190,191,193,194
16	0.00	1	2flkA	CXS	Rep, Mult	119,120,123
17	0.00	1	1xhfB	BF2	Rep, Mult	83,85
18	0.00	1	3chyA	SO4	Rep, Mult	111,112,125,128
19	0.00	1	1nxtA	XE	Rep, Mult	76,77,80,107

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	2vk1A	0.482	5.31	0.077	0.734	4.1.1.1	NA
2	0.060	1etuA	0.227	5.78	0.052	0.369	3.6.5.3	NA
3	0.060	1f60A	0.487	4.87	0.046	0.714	3.6.5.3	NA
4	0.060	3ey9A	0.461	5.10	0.057	0.686	1.2.2.2	194
5	0.060	2ji8A	0.448	5.49	0.041	0.730	4.1.1.8	31
6	0.060	1zpdA	0.484	5.06	0.072	0.730	4.1.1.1	NA
7	0.060	2wvhA	0.481	5.17	0.071	0.730	4.1.1.1	26
8	0.060	1d2eA	0.470	5.08	0.095	0.722	3.6.5.3	NA
9	0.060	1ovmA	0.476	5.08	0.068	0.726	4.1.1.74	168
10	0.060	3dnyT	0.468	5.07	0.074	0.671	3.6.5.3	67
11	0.060	1ob2A	0.497	4.60	0.078	0.694	3.6.1.48	NA
12	0.060	2djiA	0.466	5.47	0.038	0.722	1.2.3.3	104,130
13	0.060	2vycA	0.505	4.33	0.083	0.659	4.1.1.19	NA
14	0.060	1wdlA	0.452	5.40	0.047	0.702	5.3.3.8,5.1.2.3,4.2.1.17,1.1.1.35	75,105
15	0.060	1ybhA	0.458	5.43	0.077	0.714	2.2.1.6	219
16	0.060	2x58A	0.441	5.81	0.055	0.718	5.3.3.8,4.2.1.17,1.1.1.35	89,130
17	0.060	2ji6A	0.453	5.18	0.055	0.698	4.1.1.8	NA
18	0.060	2vbiA	0.474	5.19	0.066	0.722	4.1.1.1	NA
19	0.060	1ovmC	0.474	5.23	0.080	0.722	4.1.1.74	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.36	0.442	1.78	0.13	0.47	2jk1A	GO:0000160 GO:0000166 GO:0003677 GO:0005524 GO:0005737 GO:0006351 GO:0006355 GO:0008134 GO:0043565
1	0.36	0.429	2.06	0.14	0.47	1dbwB	GO:0000160 GO:0003677 GO:0005737 GO:0006351 GO:0006355 GO:0009399 GO:0046872
2	0.27	0.445	2.51	0.15	0.50	1l5yB	GO:0000160 GO:0000166 GO:0003677 GO:0005524 GO:0005737 GO:0006351 GO:0006355 GO:0008134 GO:0043565
3	0.25	0.444	2.92	0.07	0.51	1yioA	GO:0000160 GO:0003677 GO:0005622 GO:0006351 GO:0006355 GO:0046872
4	0.23	0.459	2.70	0.19	0.52	1ys6B	GO:0000160 GO:0000287 GO:0003677 GO:0005509 GO:0005737 GO:0005829 GO:0005886 GO:0006351 GO:0006355 GO:0044110
5	0.23	0.447	1.71	0.13	0.47	4knyB	GO:0000160 GO:0000986 GO:0001131 GO:0003677 GO:0005737 GO:0006351 GO:0006355
6	0.22	0.442	2.15	0.11	0.48	2v0nA	GO:0000160 GO:0000166 GO:0004871 GO:0005525 GO:0005737 GO:0007049 GO:0007165 GO:0016740 GO:0030154 GO:0046872 GO:0052621
7	0.22	0.450	1.44	0.13	0.47	3cfyA	GO:0000160 GO:0000166 GO:0003677 GO:0005524 GO:0005622 GO:0006351 GO:0006355 GO:0008134 GO:0043565
8	0.21	0.442	2.36	0.10	0.48	3lufB	GO:0000160 GO:0005622 GO:0046872
9	0.20	0.466	3.30	0.22	0.54	2gwrA	GO:0000160 GO:0003677 GO:0005737 GO:0005886 GO:0006351 GO:0006355 GO:0006468 GO:0044117 GO:0045893 GO:0046872
10	0.18	0.440	2.04	0.11	0.48	1i3cA	GO:0000160 GO:0005622
11	0.17	0.476	2.64	0.13	0.54	1a04A	GO:0000160 GO:0000166 GO:0003677 GO:0005524 GO:0005829 GO:0006351 GO:0006355 GO:0010468 GO:0042128 GO:0090352
12	0.16	0.452	2.18	0.08	0.50	3breB	GO:0000160 GO:0005622
13	0.15	0.444	3.20	0.09	0.52	2hqrA	GO:0000160 GO:0003677 GO:0005622 GO:0006351 GO:0006355
14	0.15	0.466	4.79	0.17	0.64	5ed4E	GO:0000160 GO:0003677 GO:0005622 GO:0005886 GO:0006351 GO:0006355 GO:0006979 GO:0009247 GO:0009405 GO:0010628 GO:0044315 GO:0045892 GO:0045893 GO:0046889
15	0.14	0.472	3.18	0.13	0.56	3q9sA	GO:0000160 GO:0003677 GO:0005622 GO:0006351 GO:0006355
16	0.14	0.443	1.99	0.14	0.48	3t8yB	GO:0000156 GO:0000160 GO:0004871 GO:0005737 GO:0006935 GO:0007165 GO:0008984 GO:0016787
17	0.07	0.502	4.66	0.08	0.69	3sy8B	GO:0000160 GO:0005622 GO:0045892 GO:0046872
18	0.07	0.477	3.72	0.09	0.58	4gvpA	GO:0000160 GO:0003677 GO:0005737 GO:0006351 GO:0006355 GO:0046677
19	0.07	0.440	3.21	0.18	0.53	1s8nA	GO:0000160 GO:0003723 GO:0005618 GO:0005622 GO:0005886 GO:0006351 GO:0006355 GO:0031564 GO:0040007

Consensus prediction of GO terms

Molecular Function	GO:0005524	GO:0043565	GO:0008134	GO:0046872
GO-Score	0.53	0.53	0.53	0.52
Biological Processes	GO:0000160	GO:0006355	GO:0044403	GO:0040007	GO:0009399
GO-Score	0.83	0.83	0.45	0.45	0.36
Cellular Component	GO:0044444	GO:0071944	GO:0016020
GO-Score	0.45	0.45	0.34

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.