Threading Zmax Znorm MUSTER 8.58 1.48 dPPAS 15.85 1.70 wdPPAS 26.64 2.86 wMUSTER 11.55 1.99 wPPAS 33.40 4.77 dPPAS2 39.20 3.73 PPAS 23.58 3.37 Env-PPAS 36.22 4.53 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=9279) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.11 0.46+-0.15 11.7+-4.5 454 0.040 model2 -3.50 424 0.010 model3 -3.84 340 0.007 model4 -3.44 310 0.011 model5 -4.25 306 0.005 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).