Threading Zmax Znorm MUSTER 8.31 1.43 dPPAS 13.26 1.43 wdPPAS 14.85 1.60 wMUSTER 10.68 1.84 wPPAS 12.24 1.75 dPPAS2 26.36 2.51 PPAS 11.34 1.62 Env-PPAS 5.83 0.73 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=1506) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -0.24 0.68+-0.12 7.6+-4.3 753 0.485 model2 -2.50 272 0.051 model3 -1.57 155 0.129 model4 -1.92 109 0.090 model5 -2.19 84 0.070 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).