Threading Zmax Znorm MUSTER 4.23 0.73 dPPAS 5.68 0.61 wdPPAS 5.12 0.55 wMUSTER 4.36 0.75 wPPAS 5.57 0.80 dPPAS2 10.35 0.99 PPAS 6.12 0.87 Env-PPAS 7.24 0.91 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=18549) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -4.11 0.28+-0.09 16.9+-2.8 2912 0.021 model2 -4.58 1145 0.013 model3 -4.89 1136 0.010 model4 -4.85 1029 0.010 model5 -5.00 807 0.009 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).