I-TASSER results

I-TASSER results for job id Rv2700

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (216 residues)
MVAQITEGTAFDKHGRPFRRRNPRPAIVVVAFLVVVTCVMWTLALTRPPDVREAAVCNPP
PQPAGSAPTNLGEQVSRTDMTDVAPAKLSDTKVHVLNASGRGGQAADIAGALQDLGFAQP
TAANDPIYAGTRLDCQGQIRFGTAGQATAAALWLVAPCTELYHDSRADDSVDLALGTDFT
TLAHNDDIDAVLANLRPGATEPSDPALLAKIHANSC

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 \| \| \| \| \| \| \| \| \| \| MVAQITEGTAFDKHGRPFRRRNPRPAIVVVAFLVVVTCVMWTLALTRPPDVREAAVCNPPPQPAGSAPTNLGEQVSRTDMTDVAPAKLSDTKVHVLNASGRGGQAADIAGALQDLGFAQPTAANDPIYAGTRLDCQGQIRFGTAGQATAAALWLVAPCTELYHDSRADDSVDLALGTDFTTLAHNDDIDAVLANLRPGATEPSDPALLAKIHANSC
Prediction	CCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEHCCCHHHHHHHHHHHCCCCEEEHCCCCCCEEEEEHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCC
Conf.Score	988888888778888866556666345558899999999999874688877666566788888888888888888887777888899875799998699998869999999999899667778877767765568999997898589999999988996899778889879999879988788855777888766888999999889887656899
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 \| \| \| \| \| \| \| \| \| \| MVAQITEGTAFDKHGRPFRRRNPRPAIVVVAFLVVVTCVMWTLALTRPPDVREAAVCNPPPQPAGSAPTNLGEQVSRTDMTDVAPAKLSDTKVHVLNASGRGGQAADIAGALQDLGFAQPTAANDPIYAGTRLDCQGQIRFGTAGQATAAALWLVAPCTELYHDSRADDSVDLALGTDFTTLAHNDDIDAVLANLRPGATEPSDPALLAKIHANSC
Prediction	744424624544674343434442100000133332132110000345453544253645454665544544542456544635425256030202112544320440153047341524524444444645141302021246135003201340441313427454330100004406514447515531551556536344373055247568
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEHCCCHHHHHHHHHHHCCCCEEEHCCCCCCEEEEEHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCC
MVAQITEGTAFDKHGRPFRRRNPRPAIVVVAFLVVVTCVMWTLALTRPPDVREAAVCNPPPQPAGSAPTNLGEQVSRTDMTDVAPAKLSDTKVHVLNASGRGGQAADIAGALQDLGFAQPTAANDPIYAGTRLDCQGQIRFGTAGQATAAALWLVAPCTELYHDSRADDSVDLALGTDFTTLAHNDDIDAVLANLRPGATEPSDPALLAKIHANSC

2m5yA

0.17

0.09

0.54

1.07

MUSTER

--------------------------------------------------------GSSPNSEDDSSAISTMTTTTAAPTSTSVKPAAPRAEVRVYNISGTEGAAARTADRLKAAGFTVTDVGNLSLPDVAA----TTVYYTEVERATADAVGRTLGAAVELRLDQPPGVIVVVTG----------------------------------------

2m5yA

0.17

0.09

0.54

1.39

dPPAS

--------------------------------------------------------GSSPNSEDDSSAISTMTTTTAAPTSTSVKPAAPRAEVRVYNISGTEGAAARTADRLKAAGFTVTDVGNLSLPDVAA----TTVYYVEGERATADAVGRTLGAAVELRLPQPPGVIVVVTG----------------------------------------

2m5yA

0.17

0.09

0.54

2.32

wdPPAS

--------------------------------------------------------GSSPNSEDDSSAISTMTTTTAAPTSTSVKPAAPRAEVRVYNISGTEGAAARTADRLKAAGFTVTDVGNLSLPDVAA----TTVYYVEGERATADAVGRTLGAAVELRLPQPPGVIVVVTG----------------------------------------

2m5yA

0.17

0.09

0.53

1.47

wMUSTER

---------------------------------------------------------SSPNSEDDSSAISTMTTTTAAPTSTSVKPAAPRAEVRVYNISGTEGAAARTADRLKAAGFTVTDVGNLSLPDVAA----TTVYYTEVERATADAVGRTLGAAVELRLDQPPGVIVVVTG----------------------------------------

2m5yA

0.17

0.09

0.54

2.81

wPPAS

--------------------------------------------------------GSSPNSEDDSSAISTMTTTTAAPTSTSVKPAAPRAEVRVYNISGTEGAAARTADRLKAAGFTVTDVGNLSLPDVAA----TTVYYVEGERATADAVGRTLGAAVELRLPQPPGVIVVVTG----------------------------------------

2m5yA

0.17

0.09

0.54

4.15

dPPAS2

--------------------------------------------------------GSSPNSEDDSSAISTMTTTTAAPTSTSVKPAAPRAEVRVYNISGTEGAAARTADRLKAAGFTVTDVGNLSLPDVAA----TTVYYVEGERATADAVGRTLGAAVELRLPQPPGVIVVVTG----------------------------------------

2m5yA

0.17

0.09

0.54

2.04

PPAS

--------------------------------------------------------GSSPNSEDDSSAISTMTTTTAAPTSTSVKPAAPRAEVRVYNISGTEGAAARTADRLKAAGFTVTDVGNLSLPDVAA----TTVYYVEGERATADAVGRTLGAAVELRLPQPPGVIVVVTG----------------------------------------

2m5yA

0.17

0.09

0.54

1.75

Env-PPAS

--------------------------------------------------------GSSPNSEDDSSAISTMTTTTAAPTSTSVKPAAPRAEVRVYNISGTEGAAARTADRLKAAGFTVTDVGNLSLPDVAA----TTVYYTEVERATADAVGRTLGAAVELRLPQPPGVIVVVTG----------------------------------------

4ke2A

0.14

0.12

0.89

0.78

MUSTER

--------------------MNIDPAARAAAAAAASKAAVTAADAAAAAATIAASAASVAAATAADDAAASIATINAASAAAKSIAAAAAMAA----KDTAAAAASAAAAAVASAAKALETINVKAAYAAATTANTAAAAAAATTAAAAAAAKATIDNAAAAKAAAVATAVSDAAATAATAAAVAAATLEAAAAKAAATAVSAAAAAAAAAIAFAA

5gaoE

0.16

1.00

0.76

dPPAS

AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAR

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-3.31

Estimated TM-score = 0.35±0.12

Estimated RMSD = 13.4±4.1Å

Download Model 2

C-score=-4.09

Download Model 3

C-score=-4.43

Download Model 4

C-score=-4.66

Download Model 5

C-score=-4.66

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	2m5yA	0.502	1.54	0.164	0.532
2	5hb2C	0.426	5.76	0.053	0.745
3	5ijnC	0.419	5.25	0.022	0.676
4	3kdpA	0.419	5.34	0.054	0.690
5	3ba6A	0.415	5.64	0.043	0.713
6	4kf7A	0.414	4.77	0.069	0.620
7	1yvlB	0.402	4.74	0.038	0.611
8	2rfoA	0.399	5.57	0.039	0.667
9	1bg1A	0.395	4.62	0.055	0.602
10	1korB	0.380	4.99	0.067	0.579

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.10	5	1mz9E	VDY	Rep, Mult	29,33,36
2	0.06	3	2a69O	MG	Rep, Mult	116,117,197,198
3	0.06	3	1mz9B	VDY	Rep, Mult	33,36,40
4	0.04	2	2dqsA	PTY	Rep, Mult	102,106,113,123
5	0.02	1	3ar3A	PTY	Rep, Mult	108,111,115
6	0.02	1	1c6mA	KR	Rep, Mult	105,106,124,174
7	0.02	1	3ij4A	CS	Rep, Mult	177,178,180
8	0.02	1	2uwfA	CA	Rep, Mult	90,160
9	0.02	1	3namA	NA	Rep, Mult	152,153,156,157,159,160
10	0.02	1	3bwxA	CA	Rep, Mult	85,98
11	0.02	1	2agvA	BHQ	Rep, Mult	93,115,148,149,154,155
12	0.02	1	3fpsA	CZA	Rep, Mult	93,109,112,113,150
13	0.02	1	2wtfB	CA	Rep, Mult	91,168
14	0.02	1	3b04D	MG	Rep, Mult	94,97
15	0.02	1	2b0qA	MG	Rep, Mult	164,178
16	0.02	1	1ztzA	III	Rep, Mult	114,116
17	0.02	1	1l6l7	BOG	Rep, Mult	28,32

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	2qytA	0.332	4.68	0.088	0.495	1.1.1.169	NA
2	0.060	3degC	0.333	5.51	0.062	0.532	3.6.5.1	NA
3	0.060	2cseW	0.350	6.00	0.053	0.630	3.6.4.13	NA
4	0.060	2c9aA	0.222	5.48	0.062	0.384	3.1.3.48	96
5	0.060	1korD	0.382	4.96	0.066	0.579	6.3.4.5	98,100,134
6	0.060	2zxqA	0.361	5.75	0.043	0.620	3.2.1.97	100,104
7	0.060	3b8eA	0.434	5.38	0.063	0.704	3.6.3.9	NA
8	0.060	1mo7A	0.244	6.14	0.070	0.454	3.6.3.9	3,107,140
9	0.060	3g61A	0.354	5.93	0.043	0.620	3.6.3.44	151
10	0.060	2v5yA	0.331	5.32	0.033	0.551	3.1.3.48	93,170,174
11	0.060	3bg3A	0.325	5.57	0.072	0.551	6.4.1.1	NA
12	0.060	1j1zA	0.384	4.98	0.067	0.579	6.3.4.5	172
13	0.060	1k92A	0.374	5.33	0.073	0.593	6.3.4.5	NA
14	0.060	2qf7B	0.289	6.08	0.034	0.537	6.4.1.1	NA
15	0.060	1hn0A	0.343	6.25	0.023	0.630	4.2.2.20	128
16	0.060	1k1xA	0.283	5.99	0.045	0.523	2.4.1.25	103,176
17	0.060	1g0dA	0.333	5.87	0.056	0.593	2.3.2.13	NA
18	0.060	1qwlA	0.329	5.89	0.066	0.574	1.11.1.6	NA
19	0.060	3kvnX	0.335	5.62	0.042	0.569	3.1.1.1	96

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.18	0.502	1.54	0.16	0.53	2m5yA	GO:0016020 GO:0016021
1	0.06	0.399	5.57	0.04	0.67	2rfoA	GO:0000055 GO:0005634 GO:0005643 GO:0006606 GO:0006810 GO:0006999 GO:0015031 GO:0016020 GO:0016973 GO:0017056 GO:0031965 GO:0044612 GO:0044615 GO:0051028 GO:0051292
2	0.06	0.318	6.00	0.06	0.59	1mhsA	GO:0000166 GO:0005524 GO:0005886 GO:0005887 GO:0006754 GO:0006810 GO:0006811 GO:0008553 GO:0015992 GO:0016020 GO:0016021 GO:0016787 GO:0016887 GO:0043231 GO:0046872 GO:0051453 GO:1902600
3	0.06	0.431	5.95	0.05	0.77	5hb2C	GO:0005634 GO:0005643 GO:0006810 GO:0015031 GO:0016020 GO:0031965 GO:0051028
4	0.06	0.419	5.25	0.02	0.68	5ijnC	GO:0002230 GO:0005634 GO:0005635 GO:0005643 GO:0006406 GO:0006409 GO:0006606 GO:0006810 GO:0007077 GO:0010827 GO:0015031 GO:0016020 GO:0016032 GO:0016925 GO:0016973 GO:0017056 GO:0019083 GO:0031047 GO:0031965 GO:0034399 GO:0051028 GO:0051292 GO:0075733 GO:0098779 GO:0098792 GO:1900034
5	0.06	0.415	5.28	0.04	0.67	2qx5A	GO:0000055 GO:0005634 GO:0005643 GO:0006606 GO:0006810 GO:0006999 GO:0015031 GO:0016020 GO:0016973 GO:0017056 GO:0031965 GO:0044612 GO:0044615 GO:0051028 GO:0051292
6	0.06	0.301	5.54	0.06	0.51	2xsnD	GO:0001666 GO:0001963 GO:0001975 GO:0003007 GO:0004497 GO:0004511 GO:0005506 GO:0005634 GO:0005737 GO:0005739 GO:0005790 GO:0005829 GO:0006585 GO:0006631 GO:0006665 GO:0007507 GO:0007601 GO:0007605 GO:0007612 GO:0007613 GO:0007617 GO:0007626 GO:0008016 GO:0008021 GO:0008198 GO:0008199 GO:0009072 GO:0009414 GO:0009416 GO:0009635 GO:0009651 GO:0009653 GO:0009887 GO:0009898 GO:0010038 GO:0010043 GO:0010259 GO:0014070 GO:0014823 GO:0015842 GO:0016137 GO:0016491 GO:0016597 GO:0016714 GO:0017085 GO:0018963 GO:0019825 GO:0019899 GO:0019904 GO:0021987 GO:0030424 GO:0030425 GO:0030659 GO:0031410 GO:0031667 GO:0032355 GO:0032496 GO:0033076 GO:0033162 GO:0034617 GO:0035094 GO:0035176 GO:0035240 GO:0035690 GO:0035900 GO:0035902 GO:0042136 GO:0042214 GO:0042416 GO:0042418 GO:0042421 GO:0042423 GO:0042462 GO:0042493 GO:0042745 GO:0042755 GO:0043005 GO:0043025 GO:0043195 GO:0043204 GO:0043434 GO:0043473 GO:0045471 GO:0045472 GO:0046684 GO:0046872 GO:0048545 GO:0048596 GO:0050890 GO:0051412 GO:0051602 GO:0052314 GO:0055114 GO:0070848 GO:0071287 GO:0071312 GO:0071316 GO:0071333 GO:0071363
7	0.06	0.322	6.09	0.04	0.56	3ixzA	GO:0000166 GO:0000287 GO:0005391 GO:0005524 GO:0005886 GO:0005887 GO:0006810 GO:0006811 GO:0006813 GO:0006814 GO:0006883 GO:0008900 GO:0010107 GO:0010248 GO:0015991 GO:0015992 GO:0016020 GO:0016021 GO:0016787 GO:0030007 GO:0036376 GO:0043231 GO:0046872
8	0.06	0.290	4.61	0.04	0.43	4oetA	GO:0043190 GO:0055085
9	0.06	0.434	5.38	0.06	0.70	3b8eA	GO:0000166 GO:0002028 GO:0005391 GO:0005524 GO:0005886 GO:0005890 GO:0006810 GO:0006811 GO:0006813 GO:0006814 GO:0006883 GO:0010107 GO:0010248 GO:0015991 GO:0016020 GO:0016021 GO:0016787 GO:0030007 GO:0030955 GO:0031402 GO:0036376 GO:0042383 GO:0043231 GO:0046872 GO:0051117 GO:0086009 GO:0090662 GO:1990573
10	0.06	0.268	5.68	0.08	0.46	4lemC	GO:0000166 GO:0003842 GO:0004029 GO:0006537 GO:0006561 GO:0008152 GO:0016491 GO:0016620 GO:0040007 GO:0055114
11	0.06	0.251	6.13	0.05	0.47	3oaaD	GO:0000166 GO:0005524 GO:0005886 GO:0006754 GO:0006810 GO:0006811 GO:0015986 GO:0015991 GO:0015992 GO:0016020 GO:0016787 GO:0016820 GO:0033178 GO:0042777 GO:0045261 GO:0046034 GO:0046933 GO:0046961
12	0.06	0.316	5.61	0.07	0.53	3j09A	GO:0000166 GO:0005507 GO:0005524 GO:0005886 GO:0006810 GO:0006811 GO:0006812 GO:0006825 GO:0016020 GO:0016021 GO:0016787 GO:0019829 GO:0030001 GO:0046872 GO:0098655
13	0.06	0.262	5.33	0.03	0.43	1nrwA	GO:0005737 GO:0016311 GO:0016787 GO:0016791 GO:0044283 GO:0046872
14	0.06	0.283	5.48	0.07	0.48	4umvA	GO:0000166 GO:0005886 GO:0006812 GO:0016020 GO:0016021 GO:0016787 GO:0019829 GO:0030001 GO:0046872 GO:0098655
15	0.06	0.245	5.75	0.05	0.43	3skxA	GO:0000166 GO:0004008 GO:0005524 GO:0005886 GO:0006810 GO:0006811 GO:0006812 GO:0006825 GO:0016020 GO:0016021 GO:0016787 GO:0019829 GO:0046872 GO:0060003 GO:0098655
16	0.06	0.261	5.24	0.03	0.42	4dwoA	GO:0005737 GO:0016311 GO:0016787 GO:0016791 GO:0044283 GO:0046872
17	0.06	0.246	5.10	0.01	0.38	2rarA	GO:0005737 GO:0016311 GO:0016787 GO:0016791 GO:0044283 GO:0046872
18	0.06	0.308	5.81	0.04	0.54	3b8cA	GO:0000166 GO:0000287 GO:0005524 GO:0005886 GO:0005887 GO:0006754 GO:0006810 GO:0006811 GO:0008553 GO:0015991 GO:0015992 GO:0016020 GO:0016021 GO:0016787 GO:0016887 GO:0046872 GO:0051453

Consensus prediction of GO terms

Molecular Function	GO:0017056	GO:0008553	GO:0046872	GO:0005524
GO-Score	0.12	0.06	0.06	0.06
Biological Processes	GO:0045184	GO:0050658
GO-Score	0.36	0.36
Cellular Component	GO:0031224	GO:0005635	GO:0031090
GO-Score	0.38	0.36	0.36

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.