Threading Zmax Znorm MUSTER 3.82 0.66 dPPAS 7.78 0.84 wdPPAS 6.74 0.72 wMUSTER 3.92 0.68 wPPAS 5.41 0.77 dPPAS2 12.56 1.20 PPAS 5.37 0.77 Env-PPAS 5.04 0.63 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=13539) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -3.18 0.36+-0.12 13.5+-4.0 3311 0.053 model2 -4.33 370 0.017 model3 -5.00 264 0.004 model4 -4.70 250 0.012 model5 -4.97 200 0.009 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).